FC929031

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: SMUF1_HUMAN (E3 ubiquitin-protein ligase SMURF1 OS=Homo sapiens GN=SMURF1 PE=1 SV=2)

HSP 1 Score: 126.716 bits (317), Expect = 1.580e-28
Identity = 87/285 (30.53%), Postives = 145/285 (50.88%), Query Frame = 2

Query:   17 YGLFKETSD--HLLYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISE-LELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYLEPLFCIQRAAGSAS---------EEALDRLPTSATCMNLLKLPP 835
            YGLF+ ++D  ++L  NP S  I+  HL +FHF+G ++  A+F G  ++  F   F  +L  K   L+DL S+DPEL++ L+++   E DI+  L+  F + +N +G   + EL P G+N+ VT EN   ++ L  N R    I  Q     +GF +LI +  +  F++ E                 + NT  +    ++  ++  FW+ +++F  E + + L+FVTG +R PL GFK       +Q + G+A          +   D LP + TC N + +PP
Sbjct:  460 YGLFQYSTDNIYMLQINPDSS-INPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWI--LENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKE-LELIIGGLDKIDLNDWKSNTR-LKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFK------ALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPP 733          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: ITCH_MOUSE (E3 ubiquitin-protein ligase Itchy OS=Mus musculus GN=Itch PE=1 SV=2)

HSP 1 Score: 126.716 bits (317), Expect = 1.580e-28
Identity = 84/270 (31.11%), Postives = 126/270 (46.67%), Query Frame = 2

Query:   41 DHLLYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISELELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYL-----EPLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            ++ L  NP S  I+  HL++F F+G  +A A+F G  +D  F+  F  ++  K   L DL S+DPE Y  LI++K    +   LE+YF +     GE    +L P G NI VT EN   +I +V+  RL+  + +Q+  F  GF +++ + ++  F+  E                 R        Y      I  FW+ +K    E + + L+FVTG  R P+ GF  L        FCI++          + LP S TC N L LPP
Sbjct:  580 NYCLQINPAS-YINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRH--AIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKE------NWLPRSHTCFNRLDLPP 840          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: SMUF1_MOUSE (E3 ubiquitin-protein ligase SMURF1 OS=Mus musculus GN=Smurf1 PE=1 SV=2)

HSP 1 Score: 126.331 bits (316), Expect = 2.064e-28
Identity = 87/285 (30.53%), Postives = 145/285 (50.88%), Query Frame = 2

Query:   17 YGLFKETSDHL--LYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISE-LELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYLEPLFCIQRAAGSAS---------EEALDRLPTSATCMNLLKLPP 835
            YGLF+ ++D++  L  NP S  I+  HL +FHF+G ++  A+F G  ++  F   F  +L  K   L+DL S+DPEL++ L+++   E DI+  L+  F + +N +G   + EL P G+N+ VT EN   ++ L  N R    I  Q     +GF +LI +  +  F++ E                 + NT  +    ++  ++  FW+ +++F  E + + L+FVTG +R PL GFK       +Q + G+A          +   D LP + TC N + +PP
Sbjct:  434 YGLFQYSTDNIYTLQINPDSS-INPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWI--LENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKE-LELIIGGLDKIDLNDWKSNTR-LKHCVADSNIVRWFWQAVETFDEERRARLLQFVTGSTRVPLQGFK------ALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPP 707          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: WWP1_MOUSE (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Mus musculus GN=Wwp1 PE=1 SV=2)

HSP 1 Score: 125.946 bits (315), Expect = 2.695e-28
Identity = 87/271 (32.10%), Postives = 129/271 (47.60%), Query Frame = 2

Query:   38 SDHLLYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISELELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYL-----EPLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            +++ L  NP S  I+  HL +F F+G  +A A+F G  +D  F+  F  ++  K   + DL S+D E Y  LI+++    +   LE+YF +     G+ T  +L  GG NI VT EN   +I L++  R +  +++Q+  FL GF +++   W+  F+E E                 R NT Y   Y      I  FW+ +K    E + + L+FVTG  R PL GF  L        FCI++            LP S TC N L LPP
Sbjct:  633 NNYCLQINPAS-TINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQR-NTVY-RHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDT------WLPRSHTCFNRLDLPP 894          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: WWP1_HUMAN (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Homo sapiens GN=WWP1 PE=1 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 2.695e-28
Identity = 87/271 (32.10%), Postives = 129/271 (47.60%), Query Frame = 2

Query:   38 SDHLLYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISELELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYL-----EPLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            +++ L  NP S  I+  HL +F F+G  +A A+F G  +D  F+  F  ++  K   + DL S+D E Y  LI+++    +   LE+YF +     G+ T  +L  GG NI VT EN   +I L++  R +  +++Q+  FL GF +++   W+  F+E E                 R NT Y   Y      I  FW+ +K    E + + L+FVTG  R PL GF  L        FCI++            LP S TC N L LPP
Sbjct:  637 NNYCLQINPAS-TINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDMEILGKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQR-NTVY-RHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLPLGGFAELMGSNGPQKFCIEKVGKDT------WLPRSHTCFNRLDLPP 898          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: HECW1_MOUSE (E3 ubiquitin-protein ligase HECW1 OS=Mus musculus GN=Hecw1 PE=2 SV=2)

HSP 1 Score: 125.946 bits (315), Expect = 2.695e-28
Identity = 90/285 (31.58%), Postives = 142/285 (49.82%), Query Frame = 2

Query:    5 FDVQYGLFKETSD--HLLYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISE-LELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYLE-----PLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            F+  YGLF+ +++  + +  +P S  + E +L++F F G +L  A+    L+D  F   F   L +    L+DL  LD E ++ L ++K  + +I++ L+L F +    +G+ TE EL  GG N +VT +N   +I  +   R+   + QQ+   LRGF +++    +++F+  E                 R NT Y GGYH  H VI  FW  ++ F+ E + + L+FVTG S  P  GF  L        FCI++     S      LP + TC N L LPP
Sbjct: 1306 FNPYYGLFEYSANDTYTVQISPMSAFV-ENYLEWFRFSGRILGLALIHQYLLDAFFTRPFYKGLLKLPCDLSDLEYLDEEFHQSLQWMK--DNNITDILDLTFTVNEEVFGQVTERELKSGGANTQVTEKNKKEYIERMVKWRVERGVVQQTEALLRGFYEVVDSRLVSVFDARELELVIAGTAEIDLNDW-RNNTEYRGGYHDGHLVIRWFWAAVERFNNEQRLRLLQFVTGTSSVPYEGFAALRGSNGLRRFCIEKWGKITS------LPRAHTCFNRLDLPP 1580          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: SUDX_DROME (E3 ubiquitin-protein ligase Su(dx) OS=Drosophila melanogaster GN=Su(dx) PE=1 SV=1)

HSP 1 Score: 124.79 bits (312), Expect = 6.005e-28
Identity = 83/275 (30.18%), Postives = 129/275 (46.91%), Query Frame = 2

Query:   26 FKETSDHLLYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISELELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYL-----EPLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            +   +++ L  NP S  ++  HLQ+F F+G  +A A++ G  +   F   F  ++  K   + D+ ++DPE Y  LI++K    D   LEL+F +     G+    EL   G+  RVT EN   +I L++  R+   I QQ+  FL GF +++  +W+  F+E E                 R NT Y   Y+     +  FW+ ++    E + + L+FVTG  R P+ GF  L        FCI++            LP S TC N L LPP
Sbjct:  660 YANKNNYSLQINPAS-YVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQR-NTIY-RHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKET------WLPRSHTCFNRLDLPP 925          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: SMUF2_MOUSE (E3 ubiquitin-protein ligase SMURF2 OS=Mus musculus GN=Smurf2 PE=2 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 1.024e-27
Identity = 89/281 (31.67%), Postives = 142/281 (50.53%), Query Frame = 2

Query:   17 YGLFKETSDHL--LYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADISE-LELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYLE-----PLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            YGLF+ + D +  L  NP S  ++ +HL +FHF+G ++  A+F G  +D  F   F  +L  K   L+D+  +DP+L+  L+++   E DI+  L+  F + +N YGE  + EL P GK+I VT EN   ++ L  N R    I  Q     +GF ++I +  +  F+E E                 + NT  +     +  V++ FW+ ++ F  E + + L+FVTG SR PL GFK L+      LF I +      +   + LP + TC N + +PP
Sbjct:  454 YGLFQYSRDDIYTLQINPDSA-VNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWI--LENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKE-LELIICGLGKIDVSDWKVNTR-LKHCTPDSNVVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQI-----DACTNNLPKAHTCFNRIDIPP 724          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: SMUF2_DANRE (E3 ubiquitin-protein ligase SMURF2 OS=Danio rerio GN=smurf2 PE=2 SV=1)

HSP 1 Score: 123.25 bits (308), Expect = 1.747e-27
Identity = 87/281 (30.96%), Postives = 142/281 (50.53%), Query Frame = 2

Query:   17 YGLFKETSDHL--LYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADIS-ELELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYLE-----PLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            YGLF+ + D +  L  NP S  ++ +HL +FHF+G ++  A+F G  +D  F   F  +L  K   L+D+ S+DP+L+  L+++   + DI+  L+  F + +N YGE  + EL P GK+I VT +    ++ L  N R    I  Q     +GF ++I +  +  F+E E                 + NT  +     +  +++ FW  ++S+  E + + L+FVTG SR PL GFK L+      LF I +   S      + LP + TC N + +PP
Sbjct:  471 YGLFQYSRDDIYTLQINPDSA-VNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWI--LDNDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTQDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKE-LELIVCGLGKIDINDWKSNTR-LKHCTPDSNIVKWFWRAVESYDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDAST-----NNLPKAHTCFNRIDIPP 741          

BLAST of FC929031 vs. ExPASy Swiss-Prot
Match: SMUF2_HUMAN (E3 ubiquitin-protein ligase SMURF2 OS=Homo sapiens GN=SMURF2 PE=1 SV=1)

HSP 1 Score: 121.709 bits (304), Expect = 5.083e-27
Identity = 87/281 (30.96%), Postives = 141/281 (50.18%), Query Frame = 2

Query:   17 YGLFKETSDHL--LYPNPGSGMIHEQHLQFFHFLGILLAKAMFEGILVDIPFATFFLSKLKRKYNYLNDLPSLDPELYRHLIFLKHYEADIS-ELELYFVILNNEYGEQTEEELLPGGKNIRVTNENVITFIHLVSNHRLNFQIRQQSSHFLRGFQQLIQKDWINMFNEHEXXXXXXXXXXXXXXXXXRQNTNYVGGYHSEHYVIEMFWEVLKSFSLENQKKFLKFVTGCSRGPLLGFKYLE-----PLFCIQRAAGSASEEALDRLPTSATCMNLLKLPP 835
            YGLF+ + D +  L  NP S  ++ +HL +FHF+G ++  A+F G  +D  F   F  +L  K   L+D+  +DP+L+  L+++   E DI+  L+  F + +N YGE  + EL P GK+I V  EN   ++ L  N R    I  Q     +GF ++I +  +  F+E E                 + NT  +     +  +++ FW+ ++ F  E + + L+FVTG SR PL GFK L+      LF I +      +   + LP + TC N + +PP
Sbjct:  454 YGLFQYSRDDIYTLQINPDSA-VNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWI--LENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKE-LELIICGLGKIDVNDWKVNTR-LKHCTPDSNIVKWFWKAVEFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQI-----DACTNNLPKAHTCFNRIDIPP 724