BQ622993

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: AK1C4_HUMAN (Aldo-keto reductase family 1 member C4 OS=Homo sapiens GN=AKR1C4 PE=1 SV=2)

HSP 1 Score: 143.28 bits (360), Expect = 1.014e-33
Identity = 85/209 (40.67%), Postives = 122/209 (58.37%), Query Frame = 1

Query:    4 MPVIGLGT-AVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAKPSEKLQSLIPKED-----LVPLDYKGVWEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTI--PPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLG 606
            MPV+G GT A  +   N        AI+ G+RH D+A  Y  E  +G AI   +  G +  R+D+F T+KLW       +V PAL+ SL+ LQ+DYVDLYL+H+P++ KP E   + +PK++        +D    WE ME+C+  GL K IGVSNF+ +++E +L    +   P  NQVE +P   Q +L +FCKSK I++ A S LG
Sbjct:   16 MPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK-REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE---TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALG 220          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: AK1D1_HUMAN (3-oxo-5-beta-steroid 4-dehydrogenase OS=Homo sapiens GN=AKR1D1 PE=1 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 1.729e-33
Identity = 84/212 (39.62%), Postives = 125/212 (58.96%), Query Frame = 1

Query:    4 MPVIGLGTAVDKKDENVMKCA--VMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAKPSEKLQSLIPKEDLVPLDYK-----GVWEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTI--PPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLGAA 612
            +P+IGLGT  + K      CA  V  AI  GYRH D A  Y  E  +GEAI E +  G +  R+D+F   KLW  +   ++V P L+++LR LQ+DYVDLY+I  P++ KP ++   + P+++     Y        WEAME C+  GL K +GVSNF+ +++E +L    +   P  NQVE +P + Q +L +FC+   I++TA+SPLG +
Sbjct:   18 IPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR-REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDE---IYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTS 225          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: AKCL2_RAT (1,5-anhydro-D-fructose reductase OS=Rattus norvegicus GN=Akr1e2 PE=2 SV=1)

HSP 1 Score: 142.124 bits (357), Expect = 2.258e-33
Identity = 84/208 (40.38%), Postives = 118/208 (56.73%), Query Frame = 1

Query:    1 EMPVIGLGTAVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAKPSEKLQSLIPKEDLVP--LDYKGVWEAMEECQRLGLTKFIGVSNFSSKKIEALL--AFSTIPPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLGAA 612
            ++P +GLGT   K     +  AV  AI LGYRHFD A  Y  E  +G  I E +K G++  R +LFI +KLW     + LV  A   +L  L +DY+DLYLIHWP+  KP +K   L     ++P    +   WEAME+    GL K IGVSNF+ ++++ LL      I P  NQ+E +P   Q+ L +FC  +++ VTA+ PLG +
Sbjct:    3 QIPTVGLGTW--KASPGEVTDAVKVAINLGYRHFDCAYLYHNESEVGMGIKEKIKEGVVK-RDELFIVSKLWCTYHKQSLVKTACINTLEALNLDYLDLYLIHWPMGFKPGDKDIPLDRSGKVIPSHTSFLDTWEAMEDLVIEGLVKNIGVSNFNHEQLDRLLNKPGLRIKPITNQIECHPYLNQKSLIDFCHGRNVSVTAYRPLGGS 207          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: YBN4_SCHPO (Uncharacterized oxidoreductase C8E4.04 OS=Schizosaccharomyces pombe GN=SPBC8E4.04 PE=2 SV=1)

HSP 1 Score: 141.354 bits (355), Expect = 3.852e-33
Identity = 84/219 (38.36%), Postives = 132/219 (60.27%), Query Frame = 1

Query:    1 EMPVIGLGTAVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVP-ALKKSLRTLQMDYVDLYLIHWPIS--AKPSEKLQSLIPKEDLVPLDYKGV-----WEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTIPPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLGAAGSSWGTN 633
            ++P IGLGT    KDE   K AV  A+K GYRH DTA  YG E+ +GE I E+        R D+++T+KLW N AHR  +VP AL+K+L+ L ++Y+D YLIHWP +  + P E     +P+ +   L Y+ V     W+AMEE    G  ++IG+SNF+++ ++ +L  + + P+++Q+E++P   Q +  E  K   I V+A+SPL     ++ ++
Sbjct:   22 KIPSIGLGTWRSGKDET--KNAVCAALKAGYRHIDTAHIYGNEKEIGEGIRESG-----VPRTDIWVTSKLWCN-AHRAGLVPLALEKTLQDLNLEYIDAYLIHWPFALLSGPEE-----LPRNEKGELIYEDVPIEETWQAMEELLETGKVRYIGISNFNNEYLDRVLKIAKVKPTIHQMELHPYLPQTEYLEKHKKLQIHVSAYSPLANQNDAYNSD 227          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 140.969 bits (354), Expect = 5.030e-33
Identity = 75/203 (36.95%), Postives = 125/203 (61.58%), Query Frame = 1

Query:    1 EMPVIGLGTAVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAK-PSEKLQSLIPKEDLVPLDYKGVWEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTIPPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLG 606
            ++P++G GT   K +  ++  AV  A+  GYRH D A+ Y  E+ +GEA  +         R+D+FIT+KLW     ++ V PAL+++L  L + Y+DLYL+HWP++ +  S  +Q+    ++ V +  +  WE ME+    GL K IG+SNF+ + +  +L+++ I P+ NQVE++P   Q +L++FC   +I +TA+SPLG
Sbjct:   12 KIPLVGFGTW--KAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFVSI--RETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLG 210          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: ALRB_DICDI (Aldose reductase B OS=Dictyostelium discoideum GN=alrB PE=3 SV=2)

HSP 1 Score: 140.584 bits (353), Expect = 6.570e-33
Identity = 83/208 (39.90%), Postives = 119/208 (57.21%), Query Frame = 1

Query:    4 MPVIGLGTAVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPIS---AKPSEKLQSLIPKED----LVPLDYKGVWEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTIPPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLG 606
            +P+IGLGT    K   V   AV  A+K GYRH D A+ Y  E+ +G A+ E    G +  R+D+F  +KLW +  H  LV    +K+L  L ++Y+DLYLIHWPI+   A PS      +   D    L  +  +  W+ ME+    GL K IGVSNF+ + +  LL ++ I P++NQVE++P   Q  L+ FC    I++TA+SPLG
Sbjct:   17 IPMIGLGTYNGAKVGEVGD-AVKVALKSGYRHIDGAAIYMNEKEIGHALKEVFAEGEIK-REDIFYVSKLWNSCHHASLVRKHCEKTLEDLGLEYLDLYLIHWPIAFENADPSGTTTQPLRDSDGEPVLAAVSIRETWQEMEKLVEYGLVKSIGVSNFNVQNLVDLLTYAKIKPAINQVEVHPYLSQPNLKYFCDRYGIVLTAYSPLG 222          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: AKCL2_PIG (1,5-anhydro-D-fructose reductase OS=Sus scrofa GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 140.198 bits (352), Expect = 8.580e-33
Identity = 86/214 (40.19%), Postives = 125/214 (58.41%), Query Frame = 1

Query:    1 EMPVIGLGTAVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAKPSEKLQSLIPKEDLV---PLDYKGVWEAMEECQRLGLTKFIGVSNFSSKKIEALLAFST--IPPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLGAAGSSWG 627
            ++PV+GLGT      E  +  AV  AI  GYRHFD A  Y  E  +G  I   +  G++  R+DLFI +KLW     + LV  A  +SL+ L++ Y+DLYLIHWP+  KP E +   + +  ++     D+   WEAME+    GL + IGVSNF+ +++E LL      + P  NQ+E +P   Q++L  FC+S+++ VTA+ PLG  GSS G
Sbjct:    3 KIPVLGLGTWQAAPGE--VTEAVKVAIDTGYRHFDCAYLYHNENEVGVGIQAKIDEGVVR-REDLFIVSKLWCTCHKKSLVKSACTRSLKALKLQYLDLYLIHWPMGFKPGE-VDLPVDRSGMIVASNTDFLDTWEAMEDLVIEGLVRAIGVSNFNHEQLERLLNKPNLRVKPVTNQIECHPYLTQKKLISFCQSRNVSVTAYRPLG--GSSEG 210          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 139.428 bits (350), Expect = 1.464e-32
Identity = 83/221 (37.56%), Postives = 129/221 (58.37%), Query Frame = 1

Query:    4 MPVIGLGTAVDKKDENVMKCAVME---AIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAKPSEKLQSLIPKED-----LVPLDYKGVWEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTIP--PSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLGAAGSSWGTNQ 636
            +PV+G GT     +EN+ K ++     AI +G+RH D +  Y  E  +G+AI   ++ G +  R+D+F T+KLW      +LV P+L+ SLR L +DYVDLYLIH+P+S KP ++   L+P+++     L  +D    WEAME+C+  GL K IGVSNF+ +++E +L    +   P  NQVE +    Q +L  +CK   I++ A+  LG     +  N+
Sbjct:   16 IPVLGFGTYAT--EENLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTVK-REDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLKPGDE---LLPQDEHGNLILDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGTQRYKYCINE 230          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: XYL1_PICST (NAD(P)H-dependent D-xylose reductase OS=Pichia stipitis GN=XYL1 PE=3 SV=1)

HSP 1 Score: 138.658 bits (348), Expect = 2.496e-32
Identity = 86/217 (39.63%), Postives = 123/217 (56.68%), Query Frame = 1

Query:    1 EMPVIGLGTAVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAKPSEKLQSLIPKEDLVP----------LDYKGV-----WEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTIPPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLG 606
            +MP +G G    K D +     +  AIK GYR FD A +Y  E+ +G  + +A+  G++  R+DLF+T+KLW N  H D V  AL ++L  LQ+DYVDL+LIH+P++ K        +P E+  P           DY+ V     W+A+E+  + G  + IGVSNF    +  LL  +TI PSV QVE +P  QQ +L EF +S+ I VTA+S  G
Sbjct:   11 DMPAVGFGCW--KVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEGIVK-REDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFK-------FVPLEEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFG 217          

BLAST of BQ622993 vs. ExPASy Swiss-Prot
Match: GRE3_YEAST (NADPH-dependent aldose reductase GRE3 OS=Saccharomyces cerevisiae GN=GRE3 PE=1 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 3.261e-32
Identity = 90/221 (40.72%), Postives = 121/221 (54.75%), Query Frame = 1

Query:    1 EMPVIGLGTAVDKKDENVMKCAVMEAIKLGYRHFDTASEYGTERALGEAIDEALKLGLLTTRQDLFITTKLWLNDAHRDLVVPALKKSLRTLQMDYVDLYLIHWPISAKPSEKLQSLIPKEDLVPLDY--------KG-----------VWEAMEECQRLGLTKFIGVSNFSSKKIEALLAFSTIPPSVNQVEMNPAWQQRQLREFCKSKSIIVTAFSPLG 606
            +MP++GLG    K D+ V    + EAIKLGYR FD A +YG E+ +GE I +A+  GL++ R+D+F+ +KLW N  H D V  ALKK+L  + +DY+DLY IH+PI+ K        +P E+  P  +        KG            + A+EEC   GL K IGVSNF    I+ LL    I P   Q+E +P   Q  L EFCK   I V A+S  G
Sbjct:   12 KMPLVGLGCW--KIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVS-RKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK-------YVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFG 222