CB294009

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK3_CAEBR (Glycogen synthase kinase-3 OS=Caenorhabditis briggsae GN=gsk-3 PE=3 SV=1)

HSP 1 Score: 160.999 bits (406), Expect = 4.603e-39
Identity = 78/155 (50.32%), Postives = 113/155 (72.90%), Query Frame = 2

Query:  170 DKEMSAAVVDGSDHVTGHIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            +K++ +  +     VT  + S    G + + +  ISY  ++V+G GSFG+VF AK   T E VAIKKVLQD+R+KNRELQ+MR ++HPN++ LK+ F+S+  +K+EL+LNL++EYVPE++YRV +HYS   Q +P+IYVKLY YQ+ R LAYIH+
Sbjct:    2 NKQLLSCSLKSGKQVTMVVASVATDGVDQQVE--ISYYDQKVIGNGSFGVVFLAKLSTTNEMVAIKKVLQDKRFKNRELQIMRKLNHPNIVKLKYFFYSSGDKKDELYLNLILEYVPETVYRVARHYSKQRQSIPMIYVKLYMYQLLRSLAYIHS 154          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK3A_RAT (Glycogen synthase kinase-3 alpha OS=Rattus norvegicus GN=Gsk3a PE=1 SV=1)

HSP 1 Score: 156.762 bits (395), Expect = 8.681e-38
Identity = 72/130 (55.38%), Postives = 104/130 (80.00%), Query Frame = 2

Query:  245 GKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            G+  E  Q ++Y   +V+G GSFG+V+QA+  ET E VAIKKVLQD+R+KNRELQ+MR +DH N++ L++ F+S+  +K+EL+LNLV+EYVPE++YRV +H++ A   +P+IYVK+Y YQ+FR LAYIH+
Sbjct:  108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHS 237          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK3A_HUMAN (Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2)

HSP 1 Score: 156.762 bits (395), Expect = 8.681e-38
Identity = 71/130 (54.62%), Postives = 104/130 (80.00%), Query Frame = 2

Query:  245 GKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            G+  E  Q ++Y   +V+G GSFG+V+QA+  ET E VAIKKVLQD+R+KNRELQ+MR +DH N++ L++ F+S+  +K+EL+LNLV+EYVPE++YRV +H++ A   +P++YVK+Y YQ+FR LAYIH+
Sbjct:  108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHS 237          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK3A_MOUSE (Glycogen synthase kinase-3 alpha OS=Mus musculus GN=Gsk3a PE=1 SV=2)

HSP 1 Score: 155.606 bits (392), Expect = 1.934e-37
Identity = 71/130 (54.62%), Postives = 103/130 (79.23%), Query Frame = 2

Query:  245 GKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            G+  E  Q ++Y   +V+G GSFG+V+QA+  ET E VAIKKVLQD+R+KNRELQ+MR +DH N++ L++ F+S+  +K+EL+LNLV+EYVPE++YRV +H++ A    P+IY+K+Y YQ+FR LAYIH+
Sbjct:  108 GQGPERSQEVAYTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHS 237          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: SGG_DROME (Protein kinase shaggy OS=Drosophila melanogaster GN=sgg PE=1 SV=2)

HSP 1 Score: 153.295 bits (386), Expect = 9.598e-37
Identity = 71/141 (50.35%), Postives = 107/141 (75.89%), Query Frame = 2

Query:  218 GHIISTTIG--GKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            G  I+T +   G+  +  Q +SY   +V+G GSFG+VFQAK  +TGE VAIKKVLQDRR+KNRELQ+MR ++H N++ L + F+S+  +++E+FLNLV+EY+PE++Y+V + Y+   Q +P+ +++LY YQ+FR LAYIH+
Sbjct:  585 GSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHS 725          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK3_DICDI (Glycogen synthase kinase-3 OS=Dictyostelium discoideum GN=gskA PE=1 SV=2)

HSP 1 Score: 142.51 bits (358), Expect = 1.694e-33
Identity = 66/120 (55.00%), Postives = 96/120 (80.00%), Query Frame = 2

Query:  272 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFSTTRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            + Y+ E V+G GSFG+V QA   +T E VAIKKVLQD+RYKNRELQ+M++++H N++SLK+ F+ T+  +E++LNLV+EYVP+++YRV +HYS + Q +P I+VKLY YQ+ R + YIH+
Sbjct:   54 VCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFY-TSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHS 172          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK3H_DROME (Putative glycogen synthase kinase-3 homolog OS=Drosophila melanogaster GN=gskt PE=2 SV=1)

HSP 1 Score: 142.124 bits (357), Expect = 2.213e-33
Identity = 66/121 (54.55%), Postives = 96/121 (79.34%), Query Frame = 2

Query:  272 ISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            ISY   +VVG GSFG+VFQAK + + E VAIKKVLQDRR+KNRELQ+MR + H N+I+LK  FFS+  +++E++LNLVME++PE++Y+V + Y+ A Q +P+ +V+LY YQ+ R + Y+H+
Sbjct:   31 ISYTDAKVVGNGSFGVVFQAKMVPSNEMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHS 151          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK3_SCHPO (Protein kinase gsk3 OS=Schizosaccharomyces pombe GN=gsk3 PE=1 SV=3)

HSP 1 Score: 136.732 bits (343), Expect = 9.297e-32
Identity = 66/136 (48.53%), Postives = 96/136 (70.59%), Query Frame = 2

Query:  224 IISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST-TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIH 628
            I  T   G  GE KQ +SY + +VVG+GSFG+V Q   +E+    AIK+VLQD+R+KNRELQ+MR+M HPN++ L   +++T    +E++LNLV+E++PE++YR  + Y+     MP++ VKLY YQ+ R LAYIH
Sbjct:   15 IKETARDGSTGEVKQ-LSYTSSKVVGSGSFGVVMQVHLIESDSKAAIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIH 149          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: MRK1_YEAST (Serine/threonine-protein kinase MRK1 OS=Saccharomyces cerevisiae GN=MRK1 PE=1 SV=2)

HSP 1 Score: 134.806 bits (338), Expect = 3.533e-31
Identity = 61/136 (44.85%), Postives = 92/136 (67.65%), Query Frame = 2

Query:  221 HIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFSTTRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIH 628
            H   T +  KN      ISY    VVG GSFG+V     +ET + VAIKKVLQDRRYKNREL+ M+++ HPN + L++ F+    ++E++LNLV++Y+P+S+Y+ L+H+ +   +MP + +K Y YQ+F+ L Y+H
Sbjct:  145 HDRKTDVDRKNHGGTIDISYPTTEVVGHGSFGVVVTTVIIETNQKVAIKKVLQDRRYKNRELETMKMLCHPNTVGLQYYFYEKDEEDEVYLNLVLDYMPQSLYQRLRHFVNLKMQMPRVEIKFYAYQLFKALNYLH 280          

BLAST of CB294009 vs. ExPASy Swiss-Prot
Match: GSK31_SCHPO (Protein kinase gsk31 OS=Schizosaccharomyces pombe GN=gsk31 PE=1 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 2.143e-28
Identity = 69/159 (43.40%), Postives = 102/159 (64.15%), Query Frame = 2

Query:  161 MADDKEMSAAVVDGSDHVTGHIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVISLKHCFFST--TRKNELFLNLVMEYVPESMYRVLKHYSSANQRMPLIYVKLYTYQIFRGLAYIHT 631
            M+DD  +   VV  +D  TG              K+TISY   RV+G+GSFG+V QAK + T   +A+K+VLQD+RYKNRELQ+MR + HPN+I L   FF T    K+E  L L++EY+PE+++  ++ Y+   + +P + +KLY +Q+FR LAY+H+
Sbjct:    1 MSDDSHLETKVV--TDGTTGE-------------KKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRELQIMRAISHPNIIKL-IAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHS 143