CK740116

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP1_HUMAN (Poly [ADP-ribose] polymerase 1 OS=Homo sapiens GN=PARP1 PE=1 SV=4)

HSP 1 Score: 104.76 bits (260), Expect = 3.186e-29
Identity = 50/91 (54.95%), Postives = 63/91 (69.23%), Query Frame = 2

Query:  170 KYLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            KY+  THA TH  + LE+ ++F +EREGE  ++  + ++L NR LLWHGSR TNF GIL+Q           TGYMFGKGIYFAD+VSKSA
Sbjct:  816 KYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPF-KQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSA 905          

HSP 2 Score: 44.2838 bits (103), Expect = 3.186e-29
Identity = 24/56 (42.86%), Postives = 37/56 (66.07%), Query Frame = 3

Query:    6 KSKVKMLEALQDIEIASRLV--GFDVDSDDSLDEKYKKLRCDIAPLPHDSEDYQLI 167
            ++KV+ML+ L DIE+A  L+  G D  S D +D  Y+KL+ DI  +  DSE+ ++I
Sbjct:  759 QAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEII 814          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP2_HUMAN (Poly [ADP-ribose] polymerase 2 OS=Homo sapiens GN=PARP2 PE=1 SV=2)

HSP 1 Score: 100.908 bits (250), Expect = 3.211e-29
Identity = 48/91 (52.75%), Postives = 66/91 (72.53%), Query Frame = 2

Query:  170 KYLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            +YL +THAPTH+D+++ L ++F +E++GE + F   +  L NRMLLWHGSR++N+VGIL+            TGYMFGKGIYFAD+ SKSA
Sbjct:  384 QYLQSTHAPTHSDYTMTLLDLFEVEKDGEKEAF---REDLHNRMLLWHGSRMSNWVGILSHGLRIAPPEAPITGYMFGKGIYFADMSSKSA 471          

HSP 2 Score: 48.1358 bits (113), Expect = 3.211e-29
Identity = 23/53 (43.40%), Postives = 38/53 (71.70%), Query Frame = 3

Query:   12 KVKMLEALQDIEIASRLVGFDVDSDDS-LDEKYKKLRCDIAPLPHDSEDYQLI 167
            K+++LEAL DIEIA +LV  ++ S +  LD+ Y+ L C + PL H+S ++++I
Sbjct:  330 KIQLLEALGDIEIAIKLVKTELQSPEHPLDQHYRNLHCALRPLDHESYEFKVI 382          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP1_XENLA (Poly [ADP-ribose] polymerase 1 (Fragment) OS=Xenopus laevis GN=parp1 PE=2 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 7.033e-29
Identity = 49/90 (54.44%), Postives = 63/90 (70.00%), Query Frame = 2

Query:  173 YLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            Y+  THA TH  + LE+ E+F ++REGE+ ++  + ++L NR LLWHGSR TNF GIL+Q           TGYMFGKGIYFAD+VSKSA
Sbjct:  800 YVKNTHADTHNAYDLEVLEIFKIDREGEYQRYKPF-KQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSA 888          

HSP 2 Score: 42.743 bits (99), Expect = 7.033e-29
Identity = 23/56 (41.07%), Postives = 37/56 (66.07%), Query Frame = 3

Query:    6 KSKVKMLEALQDIEIASRLV--GFDVDSDDSLDEKYKKLRCDIAPLPHDSEDYQLI 167
            ++KV+ML+ L DIE+A  L+  G D    D +D KY+K++ DI  +  DSE+ ++I
Sbjct:  742 QAKVQMLDNLLDIEVAYSLLRGGADDGEKDPIDVKYEKIKTDIKVVAKDSEESRII 797          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP1_CHICK (Poly [ADP-ribose] polymerase 1 OS=Gallus gallus GN=PARP1 PE=1 SV=2)

HSP 1 Score: 103.219 bits (256), Expect = 3.423e-28
Identity = 49/91 (53.85%), Postives = 63/91 (69.23%), Query Frame = 2

Query:  170 KYLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            +Y+  THA TH  + L++ E+F +EREGE  ++  + ++L NR LLWHGSR TNF GIL+Q           TGYMFGKGIYFAD+VSKSA
Sbjct:  813 QYVKNTHAATHNAYDLKVVEIFRIEREGESQRYKPF-KQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSA 902          

HSP 2 Score: 42.3578 bits (98), Expect = 3.423e-28
Identity = 26/57 (45.61%), Postives = 39/57 (68.42%), Query Frame = 3

Query:    6 KSKVKMLEALQDIEIA-SRLVGFDVDSD-DSLDEKYKKLRCDIAPLPHDSEDYQLIE 170
            ++KV+ML+ L DIE+A S L G + D D D +D  Y+KLR DI  +  DSE+ ++I+
Sbjct:  756 QAKVQMLDNLLDIEVAYSLLRGGNEDGDKDPIDINYEKLRTDIKVVDKDSEEAKIIK 812          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP2_ARATH (Poly [ADP-ribose] polymerase 2 OS=Arabidopsis thaliana GN=PARP2 PE=2 SV=1)

HSP 1 Score: 96.2857 bits (238), Expect = 1.677e-27
Identity = 45/90 (50.00%), Postives = 60/90 (66.67%), Query Frame = 2

Query:  173 YLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            Y+  THA TH+ +++E+ ++F   R  E D+F  +    KNRMLLWHGSR+TN+ GIL+Q           TGYMFGKG+YFAD+ SKSA
Sbjct:  441 YMENTHAKTHSGYTVEIAQLFRASRAVEADRFQQFSSS-KNRMLLWHGSRLTNWAGILSQGLRIAPPEAPVTGYMFGKGVYFADMFSKSA 529          

HSP 2 Score: 46.9802 bits (110), Expect = 1.677e-27
Identity = 21/55 (38.18%), Postives = 38/55 (69.09%), Query Frame = 3

Query:    6 KSKVKMLEALQDIEIASRLVGFDVD-SDDSLDEKYKKLRCDIAPLPHDSEDYQLI 167
            K K++M+EAL +IE+A++L+  D    DD L   Y++L C + P+ +DSE++ ++
Sbjct:  384 KQKIEMVEALGEIELATKLLSVDPGLQDDPLYYHYQQLNCGLTPVGNDSEEFSMV 438          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PRP2B_ORYSJ (Poly [ADP-ribose] polymerase 2-B OS=Oryza sativa subsp. japonica GN=PARP2-B PE=3 SV=2)

HSP 1 Score: 92.4337 bits (228), Expect = 2.185e-27
Identity = 42/90 (46.67%), Postives = 60/90 (66.67%), Query Frame = 2

Query:  173 YLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            YL  TH  THT +++++ ++F + R GE ++F  +     NRMLLWHGSR+TN+ GIL+Q           +G+MFGKG+YFAD+ SKSA
Sbjct:  407 YLTNTHGKTHTGYTVDIVQIFKVSRLGEMERFQKFA-SAGNRMLLWHGSRLTNWAGILSQGLRIAPPEAPISGFMFGKGVYFADMFSKSA 495          

HSP 2 Score: 50.447 bits (119), Expect = 2.185e-27
Identity = 26/57 (45.61%), Postives = 39/57 (68.42%), Query Frame = 3

Query:    6 KSKVKMLEALQDIEIASRLVGFDV-DSDDSLDEKYKKLRCDIAPLPHDSEDYQLIES 173
            K+K++M+EAL +IEIA +L+  D  D D  L  +YK+  CD  PL  DSE+Y +I++
Sbjct:  350 KAKLEMVEALSEIEIAIKLLEDDSSDQDHPLYARYKQFCCDFTPLEVDSEEYSMIKT 406          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP_DROME (Poly [ADP-ribose] polymerase OS=Drosophila melanogaster GN=Parp PE=2 SV=1)

HSP 1 Score: 101.679 bits (252), Expect = 1.421e-21
Identity = 49/91 (53.85%), Postives = 63/91 (69.23%), Query Frame = 2

Query:  170 KYLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            +Y+  THA TH  + L++ +VF + R+GE  +F  + +KL NR LLWHGSR+TNFVGIL+            TGYMFGKGIYFAD+VSKSA
Sbjct:  798 QYVKNTHASTHKSYDLKIVDVFKVSRQGEARRFKPF-KKLHNRKLLWHGSRLTNFVGILSHGLRIAPPEAPPTGYMFGKGIYFADMVSKSA 887          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP_SARPE (Poly [ADP-ribose] polymerase OS=Sarcophaga peregrina PE=1 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 7.054e-21
Identity = 48/91 (52.75%), Postives = 62/91 (68.13%), Query Frame = 2

Query:  170 KYLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKSA 442
            KY+  THA TH  + LE+ ++F + R+GE  ++  + +KL NR LLWHGSR+TNF GIL+            TGYMFGKGIYFAD+VSKSA
Sbjct:  801 KYVKNTHAETHKLYDLEVVDIFKVARQGEARRYKPF-KKLHNRRLLWHGSRLTNFAGILSHGLKIAPPEAPVTGYMFGKGIYFADMVSKSA 890          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PME1_CAEEL (Poly(ADP-ribose) polymerase pme-1 OS=Caenorhabditis elegans GN=pme-1 PE=2 SV=1)

HSP 1 Score: 80.8777 bits (198), Expect = 9.920e-20
Identity = 43/90 (47.78%), Postives = 53/90 (58.89%), Query Frame = 2

Query:  170 KYLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGKGIYFADLVSKS 439
            +YL  TH  TH D  +EL ++  L R+ E  KF   +R + NR LLWHGS   NF GIL Q           +GYMFGKG+YFAD+ SKS
Sbjct:  745 QYLKNTHGATH-DLKVELIDILKLNRDNESSKF---KRHIGNRRLLWHGSGKMNFAGILGQGLRIAPPEAPVSGYMFGKGVYFADMFSKS 830          

HSP 2 Score: 36.1946 bits (82), Expect = 9.920e-20
Identity = 23/60 (38.33%), Postives = 33/60 (55.00%), Query Frame = 3

Query:    6 KSKVKMLEALQDIEIA-SRLVGFDVDSDDSL-----DEKYKKLRCDIAPLPHDSEDYQLI 167
            K K  ML AL DI+ A  ++ G DV +  SL     D  Y+KL+C + PL    +D+ +I
Sbjct:  684 KEKNNMLNALLDIKFAYDQISGGDVPASTSLGIDPVDINYQKLKCIMEPLQQGCDDWNMI 743          

BLAST of CK740116 vs. ExPASy Swiss-Prot
Match: PARP1_ONCMA (Poly [ADP-ribose] polymerase 1 (Fragment) OS=Oncorhynchus masou GN=parp1 PE=2 SV=2)

HSP 1 Score: 83.5741 bits (205), Expect = 4.005e-16
Identity = 39/79 (49.37%), Postives = 51/79 (64.56%), Query Frame = 2

Query:  170 KYLHTTHAPTHTDWSLELEEVFSLEREGEFDKFSSYQRKLKNRMLLWHGSRVTNFVGILTQDXXXXXXXXXXTGYMFGK 406
            +Y+  THA TH  ++L +EE+F + REGE+ K+  +Q  L NR LLWHGSR TN+ GIL+Q           TGYMFGK
Sbjct:   58 QYVKNTHAATHNTYTLVVEEIFKIVREGEYQKYRPFQ-DLPNRQLLWHGSRATNYAGILSQGLRIAPPEAPVTGYMFGK 135