EY756567

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: SERA_METTH (D-3-phosphoglycerate dehydrogenase OS=Methanobacterium thermoautotrophicum GN=serA PE=3 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 2.814e-27
Identity = 74/221 (33.48%), Postives = 112/221 (50.68%), Query Frame = 1

Query:  178 VTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFE---EDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV*IHNQLQGTSL 831
            VT E I+ A  L+++  AGVG D++D+      G+ V     S  ++VAE  +  +L L R        V  G+W      +   +L GKT+G +G GRIG  ++ R K F  +++ +D     P + KE   +      DL+T+L + DIV ++ PLT +TR +  +D    MK    IVN ARG I+D  A+  A   G IAG + DV      +G+ L
Sbjct:   55 VTREVIEAAPRLKIIARAGVGVDNVDVKAATDRGIMVINAPESTSITVAEHSIGLMLALARKIAIADRSVKEGKWEKN--RFMGIELNGKTLGIIGMGRIGSQVVVRTKAFGMDIMVYD-----PYISKEAAEEMGVTVTDLETLLRESDIVTIHVPLTPETRHLISEDEFKLMKDTAFIVNCARGGIIDEDALYRALKDGEIAGAALDVFEEEPPEGSPL 268          

HSP 2 Score: 25.0238 bits (53), Expect = 2.814e-27
Identity = 9/25 (36.00%), Postives = 15/25 (60.00%), Query Frame = 2

Query:  818 KGHPWRYMPNQAMTPHVSGTTXDAQ 892
            +G P   + N  +TPH+  +T +AQ
Sbjct:  264 EGSPLLELENVVLTPHIGASTSEAQ 288          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: SERA_METJA (D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1)

HSP 1 Score: 122.094 bits (305), Expect = 4.494e-27
Identity = 73/228 (32.02%), Postives = 127/228 (55.70%), Query Frame = 1

Query:  115 ELEKHIPDLHVLISTPFHPAYVTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            EL + I D  VL+        VT + I+KA+ L+++  AGVG D+ID+      G+ V     ++ +SVAE  +  +L   RN       +  GEW+     ++  +L GKT+G +G GRIG+ +++R K F  N++ +D   +  ++ +  G +  +D++ +  + D + ++ PLT KTR +  +++IA MKK  +IVN ARG ++D +A+ +A   G I   + DV
Sbjct:   34 ELLEKIKDADVLVVRS--GTKVTRDVIEKAEKLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASLKRGEWDRK--RFKGIELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPY-IPKEVAESMGVELVDDINELCKRADFITLHVPLTPKTRHIIGREQIALMKKNAIIVNCARGGLIDEKALYEALKEGKIRAAALDV 256          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: GYAR_THELI (Glyoxylate reductase OS=Thermococcus litoralis GN=gyaR PE=1 SV=1)

HSP 1 Score: 120.168 bits (300), Expect = 1.708e-26
Identity = 69/212 (32.55%), Postives = 114/212 (53.77%), Query Frame = 1

Query:  178 VTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYR-----AYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            V  E ++ A  L+++    VG D+ID+      G+ V    G    + A+     +L + R  +     V SGEW  + V +       Y L+GKT+G VG GRIG+ L +R K F   ++Y+ R +  P+ E+E GA++  D +T+L + D + ++ PLT++T  M  +  +  MK   +++N +RGA++DT A++ A   G IAG   DV
Sbjct:   57 VDKELLENAPKLKIIAQYAVGYDNIDIEEATKRGIYVTNTPGVLTDATADLAFALLLAVARRIVEADAFVRSGEWKKSEVGWHPLMFLGYGLKGKTLGIVGFGRIGQALAKRAKGFGMKIIYYSRTRK-PEAEEEIGAEYV-DFETLLKESDFISLHVPLTKETYHMIGEKELKLMKPNAILINTSRGAVVDTNALIKALKEGWIAGAGLDV 266          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: SERA_MYCTU (D-3-phosphoglycerate dehydrogenase OS=Mycobacterium tuberculosis GN=serA PE=1 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.446e-25
Identity = 76/234 (32.48%), Postives = 121/234 (51.71%), Query Frame = 1

Query:  100 EGPDCE-LEKHIPDLHVLISTPFHPAYVTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            +GPD + L   +P+   L+        V AE +  A  L+++  AGVG D++D++     G+ V     SN+ S AE  L  +L   R        +    W  +  ++   ++ GKTVG VG GRIG+L+ QR+  F   ++ +D   + P    + G +    LD +L + D + V+ P T +T G+ DK+ +AK K GV+IVN ARG ++D  A+ DA + GH+     DV
Sbjct:   30 DGPDRDKLLAAVPEADALLVRS--ATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHTWKRS--SFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPY-VSPARAAQLGIELLS-LDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDV 257          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: SERA_MYCBO (D-3-phosphoglycerate dehydrogenase OS=Mycobacterium bovis GN=serA PE=3 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.446e-25
Identity = 76/234 (32.48%), Postives = 121/234 (51.71%), Query Frame = 1

Query:  100 EGPDCE-LEKHIPDLHVLISTPFHPAYVTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            +GPD + L   +P+   L+        V AE +  A  L+++  AGVG D++D++     G+ V     SN+ S AE  L  +L   R        +    W  +  ++   ++ GKTVG VG GRIG+L+ QR+  F   ++ +D   + P    + G +    LD +L + D + V+ P T +T G+ DK+ +AK K GV+IVN ARG ++D  A+ DA + GH+     DV
Sbjct:   30 DGPDRDKLLAAVPEADALLVRS--ATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHTWKRS--SFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPY-VSPARAAQLGIELLS-LDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDV 257          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: SERA_MYCLE (D-3-phosphoglycerate dehydrogenase OS=Mycobacterium leprae GN=serA PE=3 SV=1)

HSP 1 Score: 115.546 bits (288), Expect = 4.206e-25
Identity = 75/234 (32.05%), Postives = 121/234 (51.71%), Query Frame = 1

Query:  100 EGPD-CELEKHIPDLHVLISTPFHPAYVTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            +GPD  +L   +P+   L+        V AE +  A  L+++  AGVG D++D++     G+ V     SN+ S AE  L  +L   R        + +  W  +  ++   ++ GKTVG VG GRIG+L+  R+  F  +++ +D   + P    + G +     D +L + D + V+ P T +T G+ DK+ +AK K GV+IVN ARG ++D  A+ DA  SGH+     DV
Sbjct:   30 DGPDRTKLLAAVPEADALLVRS--ATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRS--SFSGTEIFGKTVGVVGLGRIGQLVAARIAAFGAHVIAYDPY-VAPARAAQLGIELMS-FDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEVALADAVRSGHVRAAGLDV 257          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: GYAR_AERPE (Glyoxylate reductase OS=Aeropyrum pernix GN=gyaR PE=3 SV=2)

HSP 1 Score: 108.612 bits (270), Expect = 4.245e-25
Identity = 68/212 (32.08%), Postives = 109/212 (51.42%), Query Frame = 1

Query:  178 VTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYR-----AYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            +  + + +A  L+++    VG D+ID+      G+ V    G    + AE     IL   R  +   H V  GEW      +        +L GKT+G +G GRIG  + +  K F   ++YH R +   ++EKE GA++   L+ +L + DI+ ++ PLT++TR +  +  +  MKK  ++VN  RGAI+DT A+V A   G IA  + DV
Sbjct:   58 IDCDLLSQAPRLRIVAQMAVGFDNIDVECATRLGIYVTNTPGVLTEATAEFTWALILAAARRVVEADHFVRWGEWWRLRTGWHPMMMLGVELRGKTLGILGMGRIGSRVAEIGKAFGMRIIYHSRSRKR-EIEKELGAEYRS-LEDLLRESDILSIHLPLTDETRHLIGESELKLMKKTAILVNTGRGAIVDTGALVKALREGWIAAAALDV 267          

HSP 2 Score: 26.9498 bits (58), Expect = 4.245e-25
Identity = 11/37 (29.73%), Postives = 17/37 (45.95%), Query Frame = 2

Query:  794 MFESTTSSKGHPWRYMPNQAMTPHVSGTTXDAQLRYA 904
            +FE    +  HP     N  + PH +  T + +LR A
Sbjct:  267 VFEEEPLNPNHPLTAFKNVVLAPHAASATRETRLRMA 303          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: GYAR_KORCO (Glyoxylate reductase OS=Korarchaeum cryptofilum (strain OPF8) GN=gyaR PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.224e-24
Identity = 69/227 (30.40%), Postives = 118/227 (51.98%), Query Frame = 1

Query:  124 KHIPDLHVLISTPFHPAYVTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAG--VAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            + + D   L+S    P  + AE  + A  L+++    VG D+ID+      G+ V    G    + A+     ++   R  +     V  G+W VA   +    YD+ G+T+G VG GRIG  + +R K F   +LY+D ++ +   EKE G ++   L+ +L + D V ++ PLTE+T  M  ++++ +MK+  ++VN +RG ++D +A+  A   G IAG   DV
Sbjct:   41 ERVKDCDALVSLLTDP--IDAEVFEAAPKLRIVAQYAVGYDNIDVKEATKRGIYVTNTPGVLTETTADFAFALLMAAARRVVEADRYVREGKWKVAWHPMMMLGYDVYGRTLGIVGMGRIGAAVARRAKGFGMRILYYDSIRRE-DFEKELGVEYVP-LEKLLEESDFVSLHVPLTEETYHMIGEEQLRRMKRTAILVNTSRGKVVDQKALYKALKEGWIAGAGLDV 263          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: SERA_PANTR (D-3-phosphoglycerate dehydrogenase OS=Pan troglodytes GN=PHGDH PE=2 SV=1)

HSP 1 Score: 112.849 bits (281), Expect = 2.726e-24
Identity = 69/207 (33.33%), Postives = 109/207 (52.66%), Query Frame = 1

Query:  178 VTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            VTA+ I  A+ LQ++  AG G D++DL      G+ V      N +S AE     I+ L R        +  G+W      +   +L GKT+G +G GRIG+ +  R++ F    + +D + + P++    G + +  L+ + P CD + V+TPL   T G+ + +  A+ KKGV +VN ARG I+D  A++ A  SG  AG + DV
Sbjct:   59 VTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERK--KFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPI-ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDV 261          

BLAST of EY756567 vs. ExPASy Swiss-Prot
Match: SERA_HUMAN (D-3-phosphoglycerate dehydrogenase OS=Homo sapiens GN=PHGDH PE=1 SV=4)

HSP 1 Score: 112.849 bits (281), Expect = 2.726e-24
Identity = 69/207 (33.33%), Postives = 109/207 (52.66%), Query Frame = 1

Query:  178 VTAERIKKAKNLQLLLTAGVGSDHIDLNXXXXXGLTVAEVTGSNVVSVAEDELMRILILVRNFLPGHHQVISGEWNVAGVAYRAYDLEGKTVGTVGCGRIGKLLLQRLKPFNCNLLYHDRVKMDPQLEKETGAKFEEDLDTMLPKCDIVVVNTPLTEKTRGMFDKDRIAKMKKGVLIVNNARGAIMDTQAVVDACSSGHIAGYSGDV 798
            VTA+ I  A+ LQ++  AG G D++DL      G+ V      N +S AE     I+ L R        +  G+W      +   +L GKT+G +G GRIG+ +  R++ F    + +D + + P++    G + +  L+ + P CD + V+TPL   T G+ + +  A+ KKGV +VN ARG I+D  A++ A  SG  AG + DV
Sbjct:   59 VTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERK--KFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPI-ISPEVSASFGVQ-QLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDV 261