EY756514

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: DYR1A_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 6.717e-18
Identity = 46/101 (45.54%), Postives = 69/101 (68.32%), Query Frame = 1

Query:   37 VCHRDVKPQNLLV-DPLTHQVKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTP 336
            + H D+KP+N+L+ +P    +K+ DFGS+  L  G+    YI SR+YR+PE++ G   Y  +ID+WS GC+L E+  G+PLF G N VDQ+ +I++VLG P
Sbjct:  283 IIHCDLKPENILLCNPKRSAIKIVDFGSSCQL--GQRIYQYIQSRFYRSPEVLLGMP-YDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIP 380          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: CDK8_AEDAE (Cell division protein kinase 8 OS=Aedes aegypti GN=Cdk8 PE=3 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 6.717e-18
Identity = 73/216 (33.80%), Postives = 109/216 (50.46%), Query Frame = 1

Query:   16 YIHTVPGVCHRDVKPQNLLVDPLTHQ---VKLCDFGSAKVL---VKGEANIS-YICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLF---------PGENAVDQLVEIIKVLGTPTR---EEIRCMNPNYT---DFRFPQ------IKAHPWHKVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFFDELREPNARLPNGRPFP 579
            Y+H+   V HRD+KP N+LV    ++   VK+ D G A++    +K  A++   + + +YRAPEL+ GA  YT +IDIW+ GC+ AELL  +P+F               DQL  I  V+G P     E+IR M  ++T   DF+         +K    HK+   +   +A  L  +LL   P+ R T+ +A   P+F E   P A +  G P P
Sbjct:  141 YLHS-NWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYANCSLVKYMERHKI---KPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIP 352          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: HIPK2_MOUSE (Homeodomain-interacting protein kinase 2 OS=Mus musculus GN=Hipk2 PE=1 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 8.772e-18
Identity = 50/104 (48.08%), Postives = 70/104 (67.31%), Query Frame = 1

Query:   34 GVCHRDVKPQNL-LVDPLT--HQVKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTP 336
            G+ H D+KP+N+ LVDP    ++VK+ DFGSA  + K   + +Y+ SRYYRAPE+I G   +  +ID+WS GCV+AEL LG PL+PG +  DQ+  I +  G P
Sbjct:  319 GLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCS-TYLQSRYYRAPEIILGLP-FCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLP 420          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: HIPK2_MESAU (Homeodomain-interacting protein kinase 2 OS=Mesocricetus auratus GN=Hipk2 PE=1 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 8.772e-18
Identity = 50/104 (48.08%), Postives = 70/104 (67.31%), Query Frame = 1

Query:   34 GVCHRDVKPQNL-LVDPLT--HQVKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTP 336
            G+ H D+KP+N+ LVDP    ++VK+ DFGSA  + K   + +Y+ SRYYRAPE+I G   +  +ID+WS GCV+AEL LG PL+PG +  DQ+  I +  G P
Sbjct:  319 GLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCS-TYLQSRYYRAPEIILGLP-FCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLP 420          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: HIPK2_HUMAN (Homeodomain-interacting protein kinase 2 OS=Homo sapiens GN=HIPK2 PE=1 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 8.772e-18
Identity = 50/104 (48.08%), Postives = 70/104 (67.31%), Query Frame = 1

Query:   34 GVCHRDVKPQNL-LVDPLT--HQVKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTP 336
            G+ H D+KP+N+ LVDP    ++VK+ DFGSA  + K   + +Y+ SRYYRAPE+I G   +  +ID+WS GCV+AEL LG PL+PG +  DQ+  I +  G P
Sbjct:  319 GLIHADLKPENIMLVDPSRQPYRVKVIDFGSASHVSKAVCS-TYLQSRYYRAPEIILGLP-FCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLP 420          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: YAK1_YEAST (Dual specificity protein kinase YAK1 OS=Saccharomyces cerevisiae GN=YAK1 PE=1 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 1.146e-17
Identity = 48/99 (48.48%), Postives = 67/99 (67.68%), Query Frame = 1

Query:   43 HRDVKPQNLLV-DPLTHQVKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTP 336
            H D+KP+N+L+  P   ++K+ DFGS+    +     +YI SR+YRAPE+I G   Y+TSID+WS GC++AEL LG P+FPG +  +QL  II  LG P
Sbjct:  494 HCDLKPENILLCAPDKPELKIIDFGSS--CEEARTVYTYIQSRFYRAPEIILGIP-YSTSIDMWSLGCIVAELFLGIPIFPGASEYNQLTRIIDTLGYP 589          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: CDK9_SCHPO (Serine/threonine-protein kinase cdk9 OS=Schizosaccharomyces pombe GN=cdk9 PE=1 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 1.146e-17
Identity = 58/184 (31.52%), Postives = 96/184 (52.17%), Query Frame = 1

Query:   37 VCHRDVKPQNLLVDPLTHQV-KLCDFGSAKVLVKGE-AN-------------ISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQ-IKAHPWH----KVFHKRMPPEAIDLASRLLQYSPSLRCTALEACAHPFF 528
            + HRD+K  NLL+D   H + K+ DFG A+V+ +   AN                + +R+YR+PEL+ G   YTT+ID+WS GC++AE+  G+P+  G + +DQL +I ++ G+PT+  +    PN+      + +++ P H    +        E   L   +L  +P  R +A  A  H +F
Sbjct:  162 ILHRDLKAANLLID--NHGILKIADFGLARVITEESYANKNPGLPPPNRREYTGCVVTRWYRSPELLLGERRYTTAIDMWSVGCIMAEMYKGRPILQGSSDLDQLDKIFRLCGSPTQATM----PNWEKLPGCEGVRSFPSHPRTLETAFFTFGKEMTSLCGAILTLNPDERLSASMALEHEYF 339          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: MBK2_CAEEL (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 OS=Caenorhabditis elegans GN=mbk-2 PE=1 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.496e-17
Identity = 70/205 (34.15%), Postives = 95/205 (46.34%), Query Frame = 1

Query:   43 HRDVKPQNLLVDPLTHQ-VKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMN-----------PNY-TDFRFPQ---IKAHPWHKVFHKRMPPEA---------------IDLASRLLQYSPSLRCTALEACAHPFFDELREPNARLPN 564
            H D+KP+N+L+       +K+ DFGS+      +   +YI SR+YRAPE+I G T+Y   ID+WS GC+LAELL G PL PGE+  DQL  II++LG P  + +               P Y T    P    + A    K    R PP +               +D   R L + P  R T  +A  H +         RLPN
Sbjct:  585 HCDLKPENVLLKQQGRSGIKVIDFGSS--CFDDQRIYTYIQSRFYRAPEVILG-TKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALIIELLGMPPPKSLETAKRARTFITSKGYPRYCTATSMPDGSVVLAGARSKRGKMRGPPASRSWSTALKNMGDELFVDFLKRCLDWDPETRMTPAQALKHKWL------RRRLPN 780          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: Y7597_DROME (Cell division cycle 2-like protein kinase CG7597 OS=Drosophila melanogaster GN=CG7597 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.954e-17
Identity = 60/186 (32.26%), Postives = 91/186 (48.92%), Query Frame = 1

Query:   43 HRDVKPQNLLVDPLTHQVKLCDFGSAKVLVKGEANISY---ICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPNYTDFRFPQIKAHPWHKVFHKR-------MPPEAIDLASRLLQYSPSLRCTALEACAHPFFDELRE---PNARLP 561
            HRD+K  N+L++    +VKL DFG A++    +    Y   + + +YR PEL+ G   Y  SID+WS GC+L EL + +PLF     + QL  I K+ G+P    +  + PN    + P        K   +R       MP  A+DL  ++L   P  R TA +A   P+  ++     P  +LP
Sbjct:  934 HRDIKCSNILMNN-RGKVKLADFGLARLYNADDRERPYTNKVITLWYRPPELLLGEERYGPSIDVWSCGCILGELFVKRPLFQANAEMAQLETISKICGSP----VPAVWPNV--IKLPLFHTLKQKKTHRRRLREDFEFMPAPALDLLDKMLDLDPDKRITAEDALRSPWLRKINPDEMPTPQLP 1112          

BLAST of EY756514 vs. ExPASy Swiss-Prot
Match: HIPK3_RAT (Homeodomain-interacting protein kinase 3 OS=Rattus norvegicus GN=Hipk3 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.954e-17
Identity = 50/104 (48.08%), Postives = 70/104 (67.31%), Query Frame = 1

Query:   34 GVCHRDVKPQNL-LVDPLT--HQVKLCDFGSAKVLVKGEANISYICSRYYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTP 336
            G+ H D+KP+N+ LVDP+   ++VK+ DFGSA  + K   + +Y+ SRYYRAPE+I G   +  +ID+WS GCV+AEL LG PL+PG    DQ+  I +  G P
Sbjct:  317 GLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKTVCS-TYLQSRYYRAPEIILGLP-FCEAIDMWSLGCVIAELFLGWPLYPGALEYDQIRYISQTQGLP 418