EY659707

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: SMUF2_DANRE (E3 ubiquitin-protein ligase SMURF2 OS=Danio rerio GN=smurf2 PE=2 SV=1)

HSP 1 Score: 223.787 bits (569), Expect = 1.132e-57
Identity = 120/304 (39.47%), Postives = 178/304 (58.55%), Query Frame = 1

Query:   31 RVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCPWR-FPALQ 936
            R+      I E+SY Q+     +DL  RL V F+GEEG+D GG+ REW  LLS  + +    LF    ++  T Q NP+S    EHLSYF FVGR++G A+F G  +D  FT  FYK +LG  +T  D+E++DPD   +L W+L+NDI+ VLD TF ++ +          ++  +EL P G++I VT++ K +YV L    R    I  Q  A  +GF E+IP  L+  F+++ELEL++  L  ID++D ++NT     +  S +++  W  V+ + +E +ARLL  VTG S+ P + F ALQ
Sbjct:  411 RIEVSREEIFEESYRQVMKMRPKDLWKRLMVKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILDNDITGVLDHTFCVEHN-------AYGEIIQHELKPNGKSIPVTQDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKELELIVCGLGKIDINDWKSNTRLKHCTPDSNIVKWFWRAVESYDEERRARLLQFVTGSSRVPLQGFKALQ 707          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: ITCH_MOUSE (E3 ubiquitin-protein ligase Itchy OS=Mus musculus GN=Itch PE=1 SV=2)

HSP 1 Score: 221.09 bits (562), Expect = 7.340e-57
Identity = 118/307 (38.44%), Postives = 177/307 (57.65%), Query Frame = 1

Query:    1 CGPVRNSSKTRVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCP 915
            C  +      ++      + EDS+ Q+   S QDL  RL V F GEEG+D GG+ REW+ LLS  + +    LF   G ++   Q NP S    +HL YF+F+GR +  ALF G+ +D  F+  FYK IL   V   D+E+IDP+++ +L W+ EN+I +  L++ FS+D    K IL E   +  ++L P G NI VTEENK +Y+ +VAE RL+  +  Q  AF EGF E++P + +  F+ +ELE+L+  + +IDL+D + +  Y  Y+  S  I   W+ V+    E++ RLL  VTG  + P
Sbjct:  500 CQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVD----KEILGE---IKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLP 799          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: ITCH_HUMAN (E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens GN=ITCH PE=1 SV=2)

HSP 1 Score: 221.09 bits (562), Expect = 7.340e-57
Identity = 118/307 (38.44%), Postives = 177/307 (57.65%), Query Frame = 1

Query:    1 CGPVRNSSKTRVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCP 915
            C  +      ++      + EDS+ Q+   S QDL  RL V F GEEG+D GG+ REW+ LLS  + +    LF   G ++   Q NP S    +HL YF+F+GR +  ALF G+ +D  F+  FYK IL   V   D+E+IDP+++ +L W+ EN+I +  L++ FS+D    K IL E   +  ++L P G NI VTEENK +Y+ +VAE RL+  +  Q  AF EGF E++P + +  F+ +ELE+L+  + +IDL+D + +  Y  Y+  S  I   W+ V+    E++ RLL  VTG  + P
Sbjct:  539 CQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVD----KEILGE---IKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLP 838          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: WWP2_MOUSE (NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Mus musculus GN=Wwp2 PE=2 SV=1)

HSP 1 Score: 219.55 bits (558), Expect = 2.136e-56
Identity = 114/300 (38.00%), Postives = 176/300 (58.67%), Query Frame = 1

Query:   22 SKTRVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCP 915
            S  ++      + EDS+ Q+      DL  RL +  +GEEG+D GG+ REW+ LLS  + +    LF   G N    Q NP S    +HL+YF+F+GR +  AL+ G+ +D  FT  FYK +L  + T  D+E+IDP+++ ++ W+ EN++ +  L+L F  D +    IL    +VT +EL  GG NI+VTEENK +Y+ L+ + R T  +  Q  AFL+GF E+ P E +  F+++ELEL++  + +ID+ D + N  Y  Y+ +S  IQ  W+VV+    E++ RLL  VTG  + P
Sbjct:  513 SHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELFFIQDME----IL---GKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLP 805          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: SUDX_DROME (E3 ubiquitin-protein ligase Su(dx) OS=Drosophila melanogaster GN=Su(dx) PE=1 SV=1)

HSP 1 Score: 218.394 bits (555), Expect = 4.758e-56
Identity = 113/300 (37.67%), Postives = 174/300 (58.00%), Query Frame = 1

Query:   22 SKTRVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCP 915
            S  ++      + EDSY+Q+      +L  RL + F+GEEG+D GG++REW+ LLS  + +    LF     N  + Q NP S    +HL YFKF+GR +  AL+ G+ +   FT  FYK +L  K+T  DIE IDP+++ +L W+ +N+I +  L+L FS+D +          Q+  +EL   G   +VTEENK +Y+ L+ E R+T  I  Q   FLEGF E++P E +  F+++ELEL++  + D+D++D + NT Y  Y+  S  +   W+ V+    E++ARLL  VTG  + P
Sbjct:  592 SHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEV-------LGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVP 884          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: HECW2_MOUSE (E3 ubiquitin-protein ligase HECW2 OS=Mus musculus GN=Hecw2 PE=2 SV=1)

HSP 1 Score: 218.009 bits (554), Expect = 6.214e-56
Identity = 120/301 (39.87%), Postives = 186/301 (61.79%), Query Frame = 1

Query:   25 KTRVRCKNSXILEDSYNQLRMRSTQDLNP-RLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEY-SGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCPW 918
            K ++  +   +LED++NQ+   S +DL   +L V F GEEG+D  G +RE++ L+SR +F+    LF    N++ T Q +P S +   H  +F+F GR++G AL    LLD  FTR FYK +L +     D+E +D ++ ++L+WM +NDI D+LDLTF+++  EE        Q+T+ EL PGG NI VTE+NK +Y++ + + R+   +  Q  + + GF E++   L+S+F+ +ELEL+I+   +IDL+D R NTEY  GY     VI+  W  V+RF+ E++ RLL  VTG S  P+
Sbjct: 1221 KLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVN--EEVF-----GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPY 1514          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: HECW2_HUMAN (E3 ubiquitin-protein ligase HECW2 OS=Homo sapiens GN=HECW2 PE=1 SV=2)

HSP 1 Score: 217.624 bits (553), Expect = 8.116e-56
Identity = 120/301 (39.87%), Postives = 185/301 (61.46%), Query Frame = 1

Query:   25 KTRVRCKNSXILEDSYNQLRMRSTQDLNP-RLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVGNES-TFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDVLDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEY-SGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCPW 918
            K ++  +   +LED++NQ+   S +DL   +L V F GEEG+D  G +RE++ L+SR +F+    LF    N++ T Q +P S +   H  +F+F GR++G AL    LLD  FTR FYK +L +     D+E +D ++ ++L+WM +NDI D+LDLTF+++  EE        Q+T+ EL PGG NI VTE+NK +Y++ + + R+   +  Q  + + GF E++   L+S+F+ +ELEL+I+   +IDL D R NTEY  GY     VI+  W  V+RF+ E++ RLL  VTG S  P+
Sbjct: 1215 KLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHDILDLTFTVN--EEVF-----GQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPY 1508          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: WWP2_HUMAN (NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens GN=WWP2 PE=1 SV=2)

HSP 1 Score: 216.468 bits (550), Expect = 1.808e-55
Identity = 113/300 (37.67%), Postives = 176/300 (58.67%), Query Frame = 1

Query:   22 SKTRVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCP 915
            S  ++      + EDS+ Q+      DL  RL +  +GEEG+D GG+ REW+ LLS  + +    LF   G N    Q NP S    +HL+YF+F+GR +  AL+ G+ +D  FT  FYK +L  + T  D+E+IDP+++ ++ W+ EN++ +  L+L F  D +    IL    +VT +EL  GG +I+VTEENK +Y+ L+ + R T  +  Q  AFL+GF E+ P E +  F+++ELEL++  + +ID+ D + +T Y  Y+  S  IQ  W+VV+    E++ RLL  VTG  + P
Sbjct:  513 SHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEGLDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRFIAMALYHGKFIDTGFTLPFYKRMLNKRPTLKDLESIDPEFYNSIVWIKENNLEECGLELYFIQDME----IL---GKVTTHELKEGGESIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDGFNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKSTIYRHYTKNSKQIQWFWQVVKEMDNEKRIRLLQFVTGTCRLP 805          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: WWP1_MOUSE (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Mus musculus GN=Wwp1 PE=1 SV=2)

HSP 1 Score: 216.468 bits (550), Expect = 1.808e-55
Identity = 115/300 (38.33%), Postives = 176/300 (58.67%), Query Frame = 1

Query:   22 SKTRVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCP 915
            S  ++      + EDS+ Q+      DL  RL V F+GEEG+D GGL REW+ LLS  + +    LF   G N    Q NP S    +HLSYF F+GR +  ALF G+ +D  F+  FYK +L  K+T  D+E+ID +++ +L W+ +N+I +  L++ FS+D +    IL    +VT ++L  GG NI VTEENK +Y+ L+ E R +  ++ Q  AFL+GF E++P + +  F+++ELE+++  + ++DL D + NT Y  Y+  S  I   W+ V+    E + RLL  VTG  + P
Sbjct:  561 SHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDME----IL---GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLP 853          

BLAST of EY659707 vs. ExPASy Swiss-Prot
Match: WWP1_HUMAN (NEDD4-like E3 ubiquitin-protein ligase WWP1 OS=Homo sapiens GN=WWP1 PE=1 SV=1)

HSP 1 Score: 216.468 bits (550), Expect = 1.808e-55
Identity = 115/300 (38.33%), Postives = 176/300 (58.67%), Query Frame = 1

Query:   22 SKTRVRCKNSXILEDSYNQLRMRSTQDLNPRLTVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTVG-NESTFQPNPNSVYQTEHLSYFKFVGRVVGKALFDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYFKNLKWMLENDISDV-LDLTFSIDADEEKLILYERAQVTDYELIPGGRNIKVTEENKHQYVDLVAEHRLTTAIRPQINAFLEGFTELIPGELISIFNDQELELLISALPDIDLDDMRANTEYSGYSAASPVIQCLWEVVQRFSKEEKARLLHLVTGPSKCP 915
            S  ++      + EDS+ Q+      DL  RL V F+GEEG+D GGL REW+ LLS  + +    LF   G N    Q NP S    +HLSYF F+GR +  ALF G+ +D  F+  FYK +L  K+T  D+E+ID +++ +L W+ +N+I +  L++ FS+D +    IL    +VT ++L  GG NI VTEENK +Y+ L+ E R +  ++ Q  AFL+GF E++P + +  F+++ELE+++  + ++DL D + NT Y  Y+  S  I   W+ V+    E + RLL  VTG  + P
Sbjct:  565 SHVKINVSRQTLFEDSFQQIMALKPYDLRRRLYVIFRGEEGLDYGGLAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASTINPDHLSYFCFIGRFIAMALFHGKFIDTGFSLPFYKRMLSKKLTIKDLESIDTEFYNSLIWIRDNNIEECGLEMYFSVDME----IL---GKVTSHDLKLGGSNILVTEENKDEYIGLMTEWRFSRGVQEQTKAFLDGFNEVVPLQWLQYFDEKELEVMLCGMQEVDLADWQRNTVYRHYTRNSKQIIWFWQFVKETDNEVRMRLLQFVTGTCRLP 857