CX671670

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: WNK1_MOUSE (Serine/threonine-protein kinase WNK1 OS=Mus musculus GN=Wnk1 PE=1 SV=1)

HSP 1 Score: 224.172 bits (570), Expect = 7.331e-58
Identity = 109/240 (45.42%), Postives = 158/240 (65.83%), Query Frame = 3

Query:  129 GRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRD--EDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKDPEVKE 842
            GR+ +++  +G G+ K VY+  D E  +EVAW +++ R         +R   E  +LK L + NI+  +  W    + +  +  +TE+ TSG L+ Y K+ + + +K L+ W +QILKGL +LHT  P +IHRDL C N+F+ G TG VKIGDLG+A +   S  A S++GTPEFMAPE+Y+E Y E VD+Y+FGMC+LEM T E PYSEC N A+IY++V+SG +P + +K+  PEVKE
Sbjct:  218 GRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSER--QRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASF-AKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKE 454          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: WNK1_HUMAN (Serine/threonine-protein kinase WNK1 OS=Homo sapiens GN=WNK1 PE=1 SV=1)

HSP 1 Score: 224.172 bits (570), Expect = 7.331e-58
Identity = 109/240 (45.42%), Postives = 158/240 (65.83%), Query Frame = 3

Query:  129 GRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRD--EDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKDPEVKE 842
            GR+ +++  +G G+ K VY+  D E  +EVAW +++ R         +R   E  +LK L + NI+  +  W    + +  +  +TE+ TSG L+ Y K+ + + +K L+ W +QILKGL +LHT  P +IHRDL C N+F+ G TG VKIGDLG+A +   S  A S++GTPEFMAPE+Y+E Y E VD+Y+FGMC+LEM T E PYSEC N A+IY++V+SG +P + +K+  PEVKE
Sbjct:  218 GRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSER--QRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASF-AKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKE 454          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: NRBP_PONAB (Nuclear receptor-binding protein OS=Pongo abelii GN=NRBP1 PE=2 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 6.467e-30
Identity = 90/266 (33.83%), Postives = 133/266 (50.00%), Query Frame = 3

Query:   81 DPSDKDSEPFIETDPTGRYGRYNELLGSGAVKKV---YRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRD--EDRNTLNFITEVCTSGNLREYRKK----HRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDE--DYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKDPEVKEF 845
            +   +D    +E  P GR+ +  E +    V  +   Y A D EEG+EV WN+V+     +     E++ +    L  L + NI+  H  W D  E++  + FITE  +SG+L+++ KK    H+ ++ KA K+W  QIL  L+YLH+ +P +IH +L C  +F+  N G +KIG +    I     +         F APE Y E  + T  VDIYSFGMC LEM  LEI      N    Y  V       A+  ++DP  +EF
Sbjct:   46 EEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHN-GLIKIGSVAPDTINNHVKTCREEQKNLHFFAPE-YGEVTNVTTAVDIYSFGMCALEMAVLEIQ----GNGESSY--VPQEAISSAIQLLEDPLQREF 303          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: NRBP_MACFA (Nuclear receptor-binding protein OS=Macaca fascicularis GN=NRBP1 PE=2 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 6.467e-30
Identity = 90/266 (33.83%), Postives = 133/266 (50.00%), Query Frame = 3

Query:   81 DPSDKDSEPFIETDPTGRYGRYNELLGSGAVKKV---YRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRD--EDRNTLNFITEVCTSGNLREYRKK----HRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDE--DYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKDPEVKEF 845
            +   +D    +E  P GR+ +  E +    V  +   Y A D EEG+EV WN+V+     +     E++ +    L  L + NI+  H  W D  E++  + FITE  +SG+L+++ KK    H+ ++ KA K+W  QIL  L+YLH+ +P +IH +L C  +F+  N G +KIG +    I     +         F APE Y E  + T  VDIYSFGMC LEM  LEI      N    Y  V       A+  ++DP  +EF
Sbjct:   46 EEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHN-GLIKIGSVAPDTINNHVKTCREEQKNLHFFAPE-YGEVTNVTTAVDIYSFGMCALEMAVLEIQ----GNGESSY--VPQEAISSAIQLLEDPLQREF 303          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: NRBP_HUMAN (Nuclear receptor-binding protein OS=Homo sapiens GN=NRBP1 PE=1 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 6.467e-30
Identity = 90/266 (33.83%), Postives = 133/266 (50.00%), Query Frame = 3

Query:   81 DPSDKDSEPFIETDPTGRYGRYNELLGSGAVKKV---YRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRD--EDRNTLNFITEVCTSGNLREYRKK----HRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDE--DYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKDPEVKEF 845
            +   +D    +E  P GR+ +  E +    V  +   Y A D EEG+EV WN+V+     +     E++ +    L  L + NI+  H  W D  E++  + FITE  +SG+L+++ KK    H+ ++ KA K+W  QIL  L+YLH+ +P +IH +L C  +F+  N G +KIG +    I     +         F APE Y E  + T  VDIYSFGMC LEM  LEI      N    Y  V       A+  ++DP  +EF
Sbjct:   46 EEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADIKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHN-GLIKIGSVAPDTINNHVKTCREEQKNLHFFAPE-YGEVTNVTTAVDIYSFGMCALEMAVLEIQ----GNGESSY--VPQEAISSAIQLLEDPLQREF 303          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: NRBP_MOUSE (Nuclear receptor-binding protein OS=Mus musculus GN=Nrbp1 PE=1 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 8.446e-30
Identity = 82/231 (35.50%), Postives = 121/231 (52.38%), Query Frame = 3

Query:   81 DPSDKDSEPFIETDPTGRYGRYNELLGSGAVKKV---YRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRD--EDRNTLNFITEVCTSGNLREYRKK----HRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHSMLGTPEFMAPELYDE--DYTELVDIYSFGMCVLEMVTLEI 740
            +   +D    +E  P GR+ +  E +    V  +   Y A D EEG+EV WN+V+     +     E++ +    L  L + NI+  H  W D  E++  + FITE  +SG+L+++ KK    H+ ++ KA K+W  QIL  L+YLH+ +P +IH +L C  +F+  N G +KIG +    I     +         F APE Y E  + T  VDIYSFGMC LEM  LEI
Sbjct:   46 EEESEDESEILEESPCGRWQKRREEVNQRNVPGIDSAYLAMDTEEGVEVVWNEVQFSERKNYKLQEEKVRAVFDNLIQLEHLNIVKFHKYWADVKENKARVIFITEYMSSGSLKQFLKKTKKNHKTMNEKAWKRWCTQILSALSYLHSCDPPIIHGNLTCDTIFIQHN-GLIKIGSVAPDTINNHVKTCREEQKNLHFFAPE-YGEVTNVTTAVDIYSFGMCALEMAVLEI 274          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: NRBP_DROME (Nuclear receptor-binding protein homolog OS=Drosophila melanogaster GN=Madm PE=1 SV=1)

HSP 1 Score: 125.561 bits (314), Expect = 3.548e-28
Identity = 83/250 (33.20%), Postives = 131/250 (52.40%), Query Frame = 3

Query:   66 PAVNSDPSDKDSEPFIETDPTGRYGRYNELLGSGAVKK---VYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDE---DRNTLNFITEVCTSGNLREYRKKHRH----VSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAI-----VGKSHSAHSMLGTPEFMAPELYDED-YTELVDIYSFGMCVLEMVTLEIPYSECDNVA 767
            P  + D S+ +SE  +E  P GR+ +  E +    V     V+ A D EEG+EV WN+V+  +  +  +  E++      L  L ++NI+  H  W D    +R  + FITE  +SG+L+++ K+ +     + +++ ++W  QIL  L+YLH+  P +IH +L C ++F+  N G VKIG +   A+      G+        G   F APE    D  T  +DIY+FGMC LEM  LEI  S  ++ A
Sbjct:   83 PRESGDDSEDESE-ILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYASLQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVVFITEYMSSGSLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCSPPIIHGNLTCDSIFIQHN-GLVKIGSVVPDAVHYSVRRGRERERERERGAHYFQAPEYGAADQLTAALDIYAFGMCALEMAALEIQPSNSESTA 330          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: NRBP_DROPS (Nuclear receptor-binding protein homolog OS=Drosophila pseudoobscura pseudoobscura GN=Madm PE=3 SV=2)

HSP 1 Score: 120.553 bits (301), Expect = 1.141e-26
Identity = 84/254 (33.07%), Postives = 131/254 (51.57%), Query Frame = 3

Query:   66 PAVNSDPSDKDSEPFIETDPTGRYGRYNELLGSGAVKK---VYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDE---DRNTLNFITEVCTSGNLREYRKKHRH----VSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAI---VGKSHSAHSM------LGTPEFMAPEL-YDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVA 767
            P  + D S+ +SE  +E  P GR+ +  E +    V     V+ A D EEG+EV WN+V+     +  +  E++      L  L ++NI+  H  W D    +R  + FITE  +SG+L+++ K+ +     + +++ ++W  QIL  L+YLH+  P +IH +L C ++F+  N G VKIG +   A+   V +     S        G   F APE    E  T  +DIY+FGMC LEM  LEI  S  ++ A
Sbjct:   96 PRESGDDSEDESE-ILEESPCGRWLKRREEVDQRDVPGIDCVHLAMDTEEGVEVVWNEVQYANMQELKSQEEKMRQVFDNLLQLDHQNIVKFHRYWTDTQQAERPRVIFITEYMSSGSLKQFLKRTKRNAKRLPLESWRRWCTQILSALSYLHSCTPPIIHGNLTCDSIFIQHN-GLVKIGSVVPDAVHYSVRRQWDRESAREQERERGAHYFQAPEYGAAEQLTAALDIYAFGMCALEMAALEIQPSNSESTA 347          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: M3K2_MOUSE (Mitogen-activated protein kinase kinase kinase 2 OS=Mus musculus GN=Map3k2 PE=1 SV=2)

HSP 1 Score: 117.087 bits (292), Expect = 1.262e-25
Identity = 70/235 (29.79%), Postives = 128/235 (54.47%), Query Frame = 3

Query:  141 RYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAM-IERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVA----AIVGKSHSAHSMLGTPEFMAPELYD-EDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKD 827
            R  +LLG GA  +VY  +D + G E+A  QV+      + +  +  L  E++LLK L ++ I+  +   RD    TL+   E+   G++++  K +  ++    +K+++QIL+G++YLH++   ++HRD+  +N+ +  +TG +K+GD G +     I        S+ GTP +M+PE+   E Y    DI+S    V+EM+T + P++E + +A I+K  +    P     + D
Sbjct:  357 RLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSN--MIVHRDIKGANI-LRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSD 588          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: M3K3_HUMAN (Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens GN=MAP3K3 PE=1 SV=2)

HSP 1 Score: 116.316 bits (290), Expect = 2.153e-25
Identity = 70/235 (29.79%), Postives = 127/235 (54.04%), Query Frame = 3

Query:  141 RYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAM-IERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVA----AIVGKSHSAHSMLGTPEFMAPELYD-EDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKD 827
            R  +LLG GA  +VY  +D + G E+A  QV+      + +  +  L  E++LLK L ++ I+  +   RD    TL    E    G++++  K +  ++    +K+++QIL+G++YLH++   ++HRD+  +N+ +  + G VK+GD G +     I        S+ GTP +M+PE+   E Y    D++S G  V+EM+T + P++E + +A I+K  +    P   + I +
Sbjct:  363 RRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMSYLHSN--MIVHRDIKGANI-LRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISE 594