CX671670

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: M3K4_HUMAN (Mitogen-activated protein kinase kinase kinase 4 OS=Homo sapiens GN=MAP3K4 PE=1 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 3.329e-18
Identity = 69/249 (27.71%), Postives = 124/249 (49.80%), Query Frame = 3

Query:  126 TGRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSA-----HSMLGTPEFMAPELYD----EDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKDPEVKEF 845
            T ++ R N++ G G   KVY     + G  +A  +++ +   +D   I+    E+++ + + + N++   Y   +  R  +    E C  G L E  +      V  ++ +SKQI   +N LH H   ++HRD+  +N+F+  ++G +K+GD G +  +  +        +S LGT  +MAPE+      E +    DI+S G  V+EMVT + P+ E ++  +I  KV  G +P    ++  PE K+F
Sbjct: 1339 TFKWQRGNKI-GEGQYGKVYTCISVDTGELMAMKEIRFQP--NDHKTIKETADELKIFEGIKHPNLV--RYFGVELHREEMYIFMEYCDEGTLEEVSRLGLQEHV--IRLYSKQITIAINVLHEHG--IVHRDIKGANIFLT-SSGLIKLGDFGCSVKLKNNAQTMPGEVNSTLGTAAYMAPEVITRAKGEGHGRAADIWSLGCVVIEMVTGKRPWHEYEHNFQIMYKVGMGHKPPIPERL-SPEGKDF 1576          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK4_PONAB (Serine/threonine-protein kinase PLK4 OS=Pongo abelii GN=PLK4 PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 5.678e-18
Identity = 64/218 (29.36%), Postives = 110/218 (50.46%), Query Frame = 3

Query:  141 RYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKH-RHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAH-SMLGTPEFMAPELYDEDYTEL-VDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKV 785
            +   LLG G+   VYRA     G+EVA   +  +       M++R+ +EV++   L + +I+ L+  +  ED N +  + E+C +G +  Y K   +  S    + +  QI+ G+ YLH+H   ++HRDL  SN+ +  N   +KI D G+A  +   H  H ++ GTP +++PE+       L  D++S G C+   + +  P  + D V     KV
Sbjct:   13 KVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMY-KAGMVQRVQNEVKIHCQLKHPSILELYNYF--EDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG--ILHRDLTLSNLLLTRNM-NIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLG-CMFYTLLIGRPPFDTDTVKNTLNKV 223          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK4_HUMAN (Serine/threonine-protein kinase PLK4 OS=Homo sapiens GN=PLK4 PE=1 SV=3)

HSP 1 Score: 91.6633 bits (226), Expect = 5.678e-18
Identity = 64/218 (29.36%), Postives = 110/218 (50.46%), Query Frame = 3

Query:  141 RYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKH-RHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAH-SMLGTPEFMAPELYDEDYTEL-VDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKV 785
            +   LLG G+   VYRA     G+EVA   +  +       M++R+ +EV++   L + +I+ L+  +  ED N +  + E+C +G +  Y K   +  S    + +  QI+ G+ YLH+H   ++HRDL  SN+ +  N   +KI D G+A  +   H  H ++ GTP +++PE+       L  D++S G C+   + +  P  + D V     KV
Sbjct:   13 KVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMY-KAGMVQRVQNEVKIHCQLKHPSILELYNYF--EDSNYVYLVLEMCHNGEMNRYLKNRVKPFSENEARHFMHQIITGMLYLHSHG--ILHRDLTLSNLLLTRNM-NIKIADFGLATQLKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLG-CMFYTLLIGRPPFDTDTVKNTLNKV 223          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK3_MOUSE (Serine/threonine-protein kinase PLK3 OS=Mus musculus GN=Plk3 PE=1 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 5.678e-18
Identity = 68/241 (28.22%), Postives = 118/241 (48.96%), Query Frame = 3

Query:   66 PAVNSDPSDKDSEPFIETDP-TGRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAA-IVGKSHSAHSMLGTPEFMAPE-LYDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYK 779
            P V + P   D    + TDP +GR      LLG G   + Y A D E GI  A   +  ++    P   E++ +E+ L + L +++I+   + + D D   +    E+C+  +L    K    +    ++ + +QIL GL YL  H+  ++HRDL   N F+  N  ++K+GD G+AA +        ++ GTP ++APE L  + +    D++S G CV+  +    P  E  ++ + Y+
Sbjct:   38 PEVLAGPRAPDPPGRLITDPLSGRTYTKGRLLGKGGFARCYEATDTESGIAYAVKVIP-QSRVAKPHQREKILNEIELHRDLQHRHIVRFSHHFEDADN--IYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYL--HQRGILHRDLKLGNFFITDNM-ELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPEADVWSLG-CVMYTLLCGSPPFETADLKETYR 271          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK1_XENTR (Serine/threonine-protein kinase PLK1 OS=Xenopus tropicalis GN=plk1 PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 5.678e-18
Identity = 70/248 (28.23%), Postives = 120/248 (48.39%), Query Frame = 3

Query:   66 PAVNSDPSDKDSEPFIETDPTGRYGRY--NELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVG-KSHSAHSMLGTPEFMAPE-LYDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQ 797
            P +    S     P I  DP  R  RY     LG G   K Y   D E   EV   ++  +T    P   +++  E+ + ++L +++++  H  + D D   +  + E+C   +L E  K+ + V+    + + KQ + G  YLH++   VIHRDL   N+F+N    +VKIGD G+A  V        ++ GTP ++APE L  + ++  VDI+S G C++  + +  P  E   + + Y ++   +
Sbjct:   19 PGIPGSSSSVKEIPEILVDPRTRR-RYLRGRFLGKGGFAKCYEITDLESR-EVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRHVVGFHGFFEDND--FVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTILGCQYLHSNR--VIHRDLKLGNLFLNDEM-EVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLGKKGHSFEVDIWSIG-CIMYTLLVGKPPFETSCLKETYMRIKKNE 258          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PLK1_XENLA (Serine/threonine-protein kinase PLK1 OS=Xenopus laevis GN=plk1 PE=1 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 5.678e-18
Identity = 70/248 (28.23%), Postives = 120/248 (48.39%), Query Frame = 3

Query:   66 PAVNSDPSDKDSEPFIETDPTGRYGRY--NELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVG-KSHSAHSMLGTPEFMAPE-LYDEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQ 797
            P +    S     P I  DP  R  RY     LG G   K Y   D E   EV   ++  +T    P   +++  E+ + ++L +++++  H  + D D   +  + E+C   +L E  K+ + V+    + + KQ + G  YLH++   VIHRDL   N+F+N    +VKIGD G+A  V        ++ GTP ++APE L  + ++  VDI+S G C++  + +  P  E   + + Y ++   +
Sbjct:   19 PGIPGSSSAVKEIPEILVDPRTRR-RYLRGRFLGKGGFAKCYEITDLESR-EVFAGKIVPKTMLLKPHQKDKMTMEIAIQRSLDHRHVVGFHGFFEDND--FVYVVLELCRRRSLLELHKRRKAVTEPEARYYLKQTISGCQYLHSNR--VIHRDLKLGNLFLNDEM-EVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLGKKGHSFEVDIWSIG-CIMYTLLVGKPPFETSCLKETYMRIKKNE 258          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: NEK4_MOUSE (Serine/threonine-protein kinase Nek4 OS=Mus musculus GN=Nek4 PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 5.678e-18
Identity = 70/240 (29.17%), Postives = 121/240 (50.42%), Query Frame = 3

Query:  144 YNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREYRK----KHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHS--AHSMLGTPEFMAPELY-DEDYTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSGQRPDALNKIKDPEVKE 842
            Y  ++G G+  +V     + +G +    ++ LR              E +LL  L + NI++    W   D   L  +   C  G+L  YRK    K + +    + +W  QI   L YLH  E  ++HRDL   NVF+   T  +K+GDLG+A ++ ++H   A +++GTP +M+PEL+ ++ Y    D+++ G CV EM TL+  ++  D  + +Y ++  G+ P  + K+   E+ E
Sbjct:    8 YMRVVGRGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAE--QEAQLLSQLKHPNIVTYKESWEGGD-GLLYIVMGFCEGGDL--YRKLKEQKGQLLPESQVVEWFVQIAMALQYLH--EKHILHRDLKTQNVFLT-RTNIIKVGDLGIARVL-ENHGDMASTLIGTPYYMSPELFSNKPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVY-RIIEGKLP-PMPKVYSTELAE 236          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: M3K15_HUMAN (Mitogen-activated protein kinase kinase kinase 15 OS=Homo sapiens GN=MAP3K15 PE=1 SV=2)

HSP 1 Score: 91.6633 bits (226), Expect = 5.678e-18
Identity = 63/205 (30.73%), Postives = 101/205 (49.27%), Query Frame = 3

Query:  153 LLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISLHYVWRDEDRNTLNFITEVCTSGNLREY-RKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVA-AIVGKSHSAHSMLGTPEFMAPELYDE---DYTELVDIYSFGMCVLEMVTLEIPYSE 752
            +LG G    VY   D    + +A  ++  R    D    + L  E+ L K L ++NI+   Y+    +   +    E    G+L    R K   +    +K ++KQIL+GL YLH ++  ++HRD+   NV VN  +G VKI D G +  + G +    +  GT ++MAPE+ D+    Y    DI+S G  ++EM T + P+ E
Sbjct:  657 VLGKGTYGIVYAGRDLSNQVRIAIKEIPER----DSRYSQPLHEEIALHKYLKHRNIVQ--YLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKYLHENQ--IVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHE 853          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PAK2_RAT (Serine/threonine-protein kinase PAK 2 OS=Rattus norvegicus GN=Pak2 PE=1 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 7.416e-18
Identity = 78/242 (32.23%), Postives = 120/242 (49.59%), Query Frame = 3

Query:  120 DPTGRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISL--HYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHS-MLGTPEFMAPELYDED-YTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSG----QRPDALNKI 821
            DP  +Y RY E +G GA   V+ A D   G EVA  Q+ L+         E + +E+ ++K L N NI++    Y+  DE    L  + E    G+L +   +   +    +    ++ L+ L +LH ++  VIHRD+   NV + G  G VK+ D G  A +    S  S M+GTP +MAPE+     Y   VDI+S G+  +EMV  E PY   + +  +Y   ++G    Q P+ L+ I
Sbjct:  244 DPKKKYTRY-EKIGQGASGTVFTATDVALGQEVAIKQINLQK----QPKKELIINEILVMKELKNPNIVNFLDSYLVGDE----LFVVMEYLAGGSLTDVVTE-TCMDEAQIAAVCRECLQALEFLHANQ--VIHRDIKSDNVLL-GMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPI 472          

BLAST of CX671670 vs. ExPASy Swiss-Prot
Match: PAK2_RABIT (Serine/threonine-protein kinase PAK 2 OS=Oryctolagus cuniculus GN=PAK2 PE=2 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 7.416e-18
Identity = 78/242 (32.23%), Postives = 120/242 (49.59%), Query Frame = 3

Query:  120 DPTGRYGRYNELLGSGAVKKVYRAFDQEEGIEVAWNQVKLRTFCDDPAMIERLFSEVRLLKTLANKNIISL--HYVWRDEDRNTLNFITEVCTSGNLREYRKKHRHVSVKALKKWSKQILKGLNYLHTHEPCVIHRDLNCSNVFVNGNTGQVKIGDLGVAAIVGKSHSAHS-MLGTPEFMAPELYDED-YTELVDIYSFGMCVLEMVTLEIPYSECDNVAKIYKKVSSG----QRPDALNKI 821
            DP  +Y RY E +G GA   V+ A D   G EVA  Q+ L+         E + +E+ ++K L N NI++    Y+  DE    L  + E    G+L +   +   +    +    ++ L+ L +LH ++  VIHRD+   NV + G  G VK+ D G  A +    S  S M+GTP +MAPE+     Y   VDI+S G+  +EMV  E PY   + +  +Y   ++G    Q P+ L+ I
Sbjct:  244 DPKKKYTRY-EKIGQGASGTVFTATDVALGQEVAIKQINLQK----QPKKELIINEILVMKELKNPNIVNFLDSYLVGDE----LFVVMEYLAGGSLTDVVTE-TCMDEAQIAAVCRECLQALEFLHANQ--VIHRDIKSDNVLL-GMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPI 472