FC877817

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_ARATH (Probable phosphoribosylformylglycinamidine synthase, chloroplastic OS=Arabidopsis thaliana GN=At1g74260 PE=1 SV=1)

HSP 1 Score: 420.239 bits (1079), Expect = 8.244e-117
Identity = 221/315 (70.16%), Postives = 248/315 (78.73%), Query Frame = 2

Query:    2 GEVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXX-AKGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSLFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNSSHSVEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKSRCEPSWKLSFTPSLTDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGGLVMLMFL-ICKKWSA 940
            GEVVKAPGNLVIS YVTCPDITKTVTP                AKGKRRLGGSALAQVF Q+GN+ PDL+DVPYLK VF+ VQ LI + LVSAGHDISDGGL+V ALEM+FAGN GI LDL S G SLF+TLF+EELGLVLE+SK+NLD V +KL    V+AEIIG V  S  +E+KVDG+THL+EKTS LRDMWE+TSF+LEK QRLASCVE EKEGLK R EP+WKLSF PS T+  YM+    PKVAVIREEGSNGDREMSAAFYAAGFEPWDV +SDL+ G I+LD+FRGIVFVGG      L   K W+A
Sbjct:  874 GEVVKAPGNLVISAYVTCPDITKTVTPDLKLGGDDGILLHVDLAKGKRRLGGSALAQVFGQIGNDCPDLDDVPYLKNVFDGVQALIAENLVSAGHDISDGGLVVTALEMAFAGNKGINLDLASNGISLFETLFSEELGLVLEISKTNLDAVMEKLRAFDVTAEIIGNVTDSPLIEVKVDGITHLSEKTSFLRDMWEDTSFQLEKLQRLASCVEMEKEGLKFRHEPNWKLSFIPSSTNNNYMSQGMIPKVAVIREEGSNGDREMSAAFYAAGFEPWDVTVSDLLAGDITLDQFRGIVFVGGFSYADVLDSAKGWAA 1188          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_HUMAN (Phosphoribosylformylglycinamidine synthase OS=Homo sapiens GN=PFAS PE=1 SV=3)

HSP 1 Score: 252.292 bits (643), Expect = 2.973e-66
Identity = 144/317 (45.43%), Postives = 185/317 (58.36%), Query Frame = 2

Query:    5 EVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXX-AKGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSLFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNSS--HS-VEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKSRCEPSWKLSFTPSLTDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGGLVMLMFL-ICKKWSA 940
            E V+APG+LVIS Y  CPDIT TVTP                + G+ RLGG+ALAQ F Q+G   PDL+    L R F   Q L+ D L+ +GHD+SDGGL+ C LEM+FAGN G+ +D+      +   LFAEE GLVLEV + +L  V K+  DA +    +G    +  H+ V + V+G   L E    LR +WEETSF+L++ Q    CV  E+ GL+ R  PS+ L  T              P+VA++REEGSNGDREM+ AF+ AGFE WDV M DL +GAI LD FRG+ FVGG      L   K W+A
Sbjct:  815 ETVRAPGSLVISAYAVCPDITATVTPDLKHPEGRGHLLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLKDRLLCSGHDVSDGGLVTCLLEMAFAGNCGLQVDVPVPRVDVLSVLFAEEPGLVLEVQEPDLAQVLKRYRDAGLHCLELGHTGEAGPHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDRLQAEPRCVAEEERGLRERMGPSYCLPPTFPKASVPREPGGPSPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAA 1131          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_MOUSE (Phosphoribosylformylglycinamidine synthase OS=Mus musculus GN=Pfas PE=2 SV=1)

HSP 1 Score: 241.891 bits (616), Expect = 4.018e-63
Identity = 140/317 (44.16%), Postives = 182/317 (57.41%), Query Frame = 2

Query:    5 EVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXX-AKGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSLFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEII---GQVNSSHSVEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKSRCEPSWKLSFTPSLTDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGGLVMLMFL-ICKKWSA 940
            E V+APG+LVIS Y  CPDIT TVTP                + G+ RLGG+ALAQ F Q+G   PDL+    L R F   Q L+ +  + +GHD+SDGGL+ C LEM+FAGN GI +D+ + G      LFAEE GLVLEV ++++  V ++   A +    +   G+        I V+    + E    LR +WEETSF+L+  Q    CV  EK+GLK R  PS+ L  T  +           P+VA++REEGSNGDREM+ AF+ AGFE WDV M DL +GAI LD FRG+ FVGG      L   K W+A
Sbjct:  814 ETVQAPGSLVISAYAVCPDITATVTPDLKHPGGKGHLLYVPLSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFHITQGLLKECRLCSGHDVSDGGLVTCLLEMAFAGNCGIEVDVPAPGIHALPVLFAEEPGLVLEVQEADVAGVRQRYESAGLRCLELGHTGEAGPQAMARISVNKAVVVEEPVGELRALWEETSFQLDLLQAEPRCVIEEKQGLKERTGPSYYLPPTFPVASVPCKPGGPVPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIRLDTFRGVAFVGGFSYADVLGSAKGWAA 1130          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_DICDI (Phosphoribosylformylglycinamidine synthase OS=Dictyostelium discoideum GN=purL PE=3 SV=1)

HSP 1 Score: 227.254 bits (578), Expect = 1.024e-58
Identity = 144/325 (44.31%), Postives = 188/325 (57.85%), Query Frame = 2

Query:    5 EVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXXAKG--KRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNS------LFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQV--------NSSHSVE----IKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKSRCE-----PSWKLSFTPS-LTDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDE-FRGIVFVGG 898
            E+VKAPG LV+S YV C DIT TVTP                 G     +GGSAL QVF+QVGN+ P   + P LK  F  +Q L+  +L+SAGHD SDGGL+   +EMS +GN G+ ++L    NS      + + LF+EELG VLE+ KSN   V   L    V  ++IG          N++ S E    +KV      N K S L   WEETS++LE  Q   + VESE + L  R       P++ +++  S ++ E  + A   PKVAVIREEGSNGDREM+AAF+ AGF+ +DV MSDL+NG I LDE F+G+ FVGG
Sbjct:  817 ELVKAPGALVVSTYVPCDDITLTVTPDLKLSSKDDSVILYLDLGCANNFIGGSALTQVFNQVGNDEPH-HNTPLLKNTFMAIQKLVKQQLISAGHDRSDGGLITTLIEMSLSGNRGLEINLPDTHNSDQSPLSIIKLLFSEELGAVLEIKKSNQQIVLDILKQFNVPTQVIGNTSCNNNNNNNNNGSDEDLFIVKVGDKLIYNIKLSQLSKQWEETSYQLELLQANPTFVESEMKNLLKRATGKGKGPNYNMTYKISPISKELALLANKAPKVAVIREEGSNGDREMAAAFHFAGFQAFDVTMSDLLNGNIQLDERFKGVAFVGG 1140          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_CAEEL (Probable phosphoribosylformylglycinamidine synthase OS=Caenorhabditis elegans GN=F10F2.2 PE=2 SV=2)

HSP 1 Score: 202.986 bits (515), Expect = 2.069e-51
Identity = 129/338 (38.17%), Postives = 190/338 (56.21%), Query Frame = 2

Query:    2 GEVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXXAKG--KRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDE---------LVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSL--FQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNSSHS----VEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKS------RCEPSWKLSFTPS-LTDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGGLVMLMFL-ICKKWSA 940
            GEVVK+PG LV+S Y  C ++TK V P                    K RLGGSALAQV+ Q+G++ PD+E+   + +VF  VQ L+  E         ++ AGHDISDGGLL   LEM+FAGN  I +D+     ++     LFAEE G++LEVS  N + V     +A +  + IG+ ++       V+I V+G   +NEK   LR+ WE     L +FQ     ++  +E  ++      +C+  W   + P+ + +E+Y +    P+VA+IREEGSNGDREM++AF  AGF+ +DV M+D++ G  +L+ +RG+ FVGG      L   K W+A
Sbjct:  808 GEVVKSPGTLVLSAYAPCTNVTKVVNPSLKAVPGSKILWIKIGSSEEKMRLGGSALAQVYSQIGDDCPDIENFSEISKVFSIVQQLLNREELAGPLRKPIILAGHDISDGGLLTAILEMAFAGNVSIDIDIKPPNQNIKPIDILFAEECGILLEVS--NPENVLHIFSEAGIKCQEIGKASAVFGPDAHVKIHVNGHLEINEKLVDLREEWELVGDRLGEFQTNPKSLKEAREVRRTCQKINYKCDFDWY--YNPAFIHNEQYFSTA--PRVAIIREEGSNGDREMASAFTLAGFQTFDVTMTDILAGH-TLEAYRGVAFVGGFSYADVLGSAKGWAA 1138          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_SHEDO (Phosphoribosylformylglycinamidine synthase OS=Shewanella denitrificans (strain OS217 / ATCC BAA-1090 / DSM 15013) GN=purL PE=3 SV=1)

HSP 1 Score: 191.815 bits (486), Expect = 4.769e-48
Identity = 115/300 (38.33%), Postives = 169/300 (56.33%), Query Frame = 2

Query:   11 VKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXX-AKGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSLFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNSSHSVEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKSRCEP--SWKLSFTPSL-TDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGG 898
            V +P +LVI+ +    DI  TVTP                + GK RLGGS LAQVF  +G+ +PDL+D   LK  FE +Q L+ D+ + A HD SDGGL     EM+FAGN G  +DL++   S    LF EELG V++VS++  + ++ +   A V+   IG +   + + +K        ++ S LR +W +TS++++  +    C   E    +S  +P  + KL+F PS      Y+     PK+A++RE+G N   EM+AAF  AGFE  DV MSD+++G ISLDEF+G+V  GG
Sbjct:  792 VTSPMSLVITAFGVVQDIRNTVTPELRSDKGDTALLLLDLSHGKTRLGGSCLAQVFSSLGDVAPDLDDSTTLKGFFEVMQTLVADQSILAYHDRSDGGLFTTVTEMAFAGNTGAEIDLSALQGSDLARLFNEELGAVIQVSQAQAEAITAQFIAAGVACHAIGGLTEHNKLVVKDGSRVVFQQQRSELRRLWSQTSYKMQALRDNPDCALEEFSLKQSETDPGLTVKLNFDPSQDVAAPYILKGIAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDILSGRISLDEFQGLVACGG 1091          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_DROME (Phosphoribosylformylglycinamidine synthase OS=Drosophila melanogaster GN=ade2 PE=1 SV=2)

HSP 1 Score: 191.045 bits (484), Expect = 8.135e-48
Identity = 120/319 (37.62%), Postives = 163/319 (51.10%), Query Frame = 2

Query:    2 GEVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXXA--KGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSL--------------FQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNS---SHSVEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKSRCEPSWKLSFTPSLTDEKYMNATSKP-KVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGG 898
            GE +K+PG LVIS Y  CPD+   VTP                  +   RLGGSALAQ + Q G ++P+L     L + F   Q L+GD L+ AGHD+SDGGLLVC LEM+  G  G+ +DL+     L                 LFAEE G V+EV  ++L+ V      A V    +G          V +K      L++   +L   WE TS+ELEK Q    C E+E   L+ R  P ++     ++  E  +  +S P +VAV+REEG N +REM A    A FE  DV MSDL+ G  S+ ++RG++F GG
Sbjct:  822 GETIKSPGTLVISTYAPCPDVRLKVTPDLKGPGAGSKTSLLWINLENSARLGGSALAQAYAQQGKDTPNLTRSDVLGKAFAVTQSLLGDGLIQAGHDVSDGGLLVCVLEMAIGGLSGLRVDLSEPLAKLKNFDKSVEKLNRPELAVLFAEECGWVVEVLDTDLERVRSTYEKAGVPNYYLGVTEGFGLDSRVVLKNGKSELLDQPLRVLYKKWERTSYELEKLQANPECAEAEYNSLEYRQAPQYR--GPQNVQAELTLKRSSAPVRVAVLREEGVNSEREMMACLLRANFEVHDVTMSDLLQGTASVSQYRGLIFPGG 1138          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_SHESR (Phosphoribosylformylglycinamidine synthase OS=Shewanella sp. (strain MR-7) GN=purL PE=3 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 1.062e-47
Identity = 116/302 (38.41%), Postives = 173/302 (57.28%), Query Frame = 2

Query:    5 EVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXX-AKGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSLFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNSSHSVEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCV--ESEKEGLKSRCEPSWKLSFTPSL-TDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGG 898
            + V AP +LVIS +    DI  TVTP                  GK RLGGS LAQV+ ++G+ +PDL+D   L+  FET+Q L+  + V A HD SDGGL    +EM+FAGN G+ +DL++   +  + LF EELG VL+VS+++ + ++ +   A V   +IG + +   V IK       +E    LR +W ET++ ++  +   +C   E + +  K+    +  LSF PS      Y+   + PK+A++RE+G N   EM+AAF  AGFE  DV MSD+++G ISL+EF+G+V  GG
Sbjct:  790 KTVTAPMSLVISAFGVVQDIRNTVTPELRSDKGETSLLLVDLGAGKNRLGGSCLAQVYGELGDIAPDLDDAALLRGFFETMQKLVAKKSVIAYHDRSDGGLFTTLVEMAFAGNTGLAIDLSALQGTDVERLFNEELGGVLQVSRADAELIAAQFAQAGVPCHMIGSLANDQRVTIKDGAREVFSETRVALRTLWSETTYRMQALRDNPACALEEFKLKQDKTDLGLTVNLSFDPSEDVAAPYILKGAAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDILSGRISLEEFQGLVACGG 1091          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_SHESM (Phosphoribosylformylglycinamidine synthase OS=Shewanella sp. (strain MR-4) GN=purL PE=3 SV=1)

HSP 1 Score: 190.274 bits (482), Expect = 1.388e-47
Identity = 115/302 (38.08%), Postives = 173/302 (57.28%), Query Frame = 2

Query:    5 EVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXX-AKGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSLFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNSSHSVEIKVDGLTHLNEKTSLLRDMWEETSFELEKFQRLASCVESEKEGLKSRCE--PSWKLSFTPSL-TDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGG 898
            + V AP +LVIS +    DI  TVTP                  GK RLGGS LAQV+ ++G+ +PDL+D   L+  FET+Q L+  + V A HD SDGGL    +EM+FAGN G+++DL++   +  + LF EELG VL+VS+++ + ++ +   A V   +IG + +   V IK       +E    LR +W ET++ ++  +   +C   E +  +   +   +  LSF PS      Y+   + PK+A++RE+G N   EM+AAF  AGFE  DV MSD+++G ISL+EF+G+V  GG
Sbjct:  790 KTVTAPMSLVISAFGVVQDIRNTVTPELRSDKGETSLLLVDLGAGKNRLGGSCLAQVYGELGDIAPDLDDAALLRGFFETMQKLVAKKSVIAYHDRSDGGLFTTLVEMAFAGNTGLSIDLSALQGTDVERLFNEELGGVLQVSRADAELIAAQFAQAGVPCHMIGTLANDQRVTIKDGAREVFSETRVALRTLWSETTYRMQALRDNPACALEEFKLKQDETDLGLTVNLSFDPSEDVAAPYILKGAAPKMAILREQGVNSHVEMAAAFDRAGFESLDVHMSDILSGRISLEEFQGLVACGG 1091          

BLAST of FC877817 vs. ExPASy Swiss-Prot
Match: PUR4_SHEON (Phosphoribosylformylglycinamidine synthase OS=Shewanella oneidensis GN=purL PE=3 SV=1)

HSP 1 Score: 186.422 bits (472), Expect = 2.004e-46
Identity = 114/303 (37.62%), Postives = 172/303 (56.77%), Query Frame = 2

Query:    5 EVVKAPGNLVISVYVTCPDITKTVTPXXXXXXXXXXXXXXX-AKGKRRLGGSALAQVFDQVGNESPDLEDVPYLKRVFETVQDLIGDELVSAGHDISDGGLLVCALEMSFAGNYGITLDLNSEGNSLFQTLFAEELGLVLEVSKSNLDTVSKKLHDAAVSAEIIGQVNSSHSVEIKVDGLTHLNEKTSL-LRDMWEETSFELEKFQRLASCVESEKEGLKSRCE--PSWKLSFTPSL-TDEKYMNATSKPKVAVIREEGSNGDREMSAAFYAAGFEPWDVIMSDLINGAISLDEFRGIVFVGG 898
            + V +P +LVI+ +    DI  TVTP                  G+ RLGGS LAQV+ ++G+ +PDL+D   L+  FET+Q L+ ++LV A HD SDGGL    +EM+FAGN G+ +D+     +  + LF EELG VL+VS+ N   ++ +   A V   +IG +     + IK DG   +   T + LR +W ET++ ++  +   +C   E +  +   +   +  LSF PS      Y+   + PK+A++RE+G N   EM+AAF  AGFE  DV MSD+++G ISL+EF+G+V  GG
Sbjct:  790 KTVTSPMSLVITAFGVVQDIRNTVTPELRSDKGETSLLLVDLGAGQNRLGGSCLAQVYGELGDVAPDLDDAALLRGFFETMQKLVANKLVIAYHDRSDGGLFTTLVEMAFAGNIGLDIDVEDLQGTDLERLFNEELGAVLQVSRDNAAKIAAQFAIAGVPCHVIGTLADDQCITIK-DGAREIFSDTRVALRTVWSETTYRMQAMRDNPACALEEFKLKQDETDLGLTVNLSFDPSEDVAAPYILKGAAPKMAILREQGVNSHVEMAAAFDRAGFESRDVHMSDILSGRISLEEFQGLVACGG 1091