CK935253

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: S6PD_MALDO (NADP-dependent D-sorbitol-6-phosphate dehydrogenase OS=Malus domestica GN=S6PDH PE=2 SV=1)

HSP 1 Score: 241.121 bits (614), Expect = 1.685e-104
Identity = 114/160 (71.25%), Postives = 132/160 (82.50%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYLVH+P+ TKH  +G T S L  D VL+ID TISL+ TW  ME  VS+GLVRSIG+SNY++FLTRDCLAYSK+KP V+QFETHPYFQRDSLVKFC KHG+  TAHTPLGGA AN + FG+VS LDDPVL  +A+KY ++VAQI LRWGIQR TAVI
Sbjct:  101 YLDLYLVHYPMPTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKTAVI 260          

HSP 2 Score: 160.229 bits (404), Expect = 1.685e-104
Identity = 68/97 (70.10%), Postives = 92/97 (94.85%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVLEACKDSLKKLQLD 359
            +TL++G++MP+IGLG+WR+++  ++++I+NAIKIGYRH DCAA Y++EA+VGEALAEAF TGLVKRE+LFITTK+WNSDHGHV+EACK+SL+KLQ+D
Sbjct:    4 VTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFKTGLVKREELFITTKIWNSDHGHVVEACKNSLEKLQID 100          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: A1A1A_DANRE (Alcohol dehydrogenase [NADP+] A OS=Danio rerio GN=akr1a1a PE=2 SV=2)

HSP 1 Score: 120.553 bits (301), Expect = 3.596e-50
Identity = 67/160 (41.88%), Postives = 90/160 (56.25%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P+A    G G        DG ++ D T     TW AME LV  GL ++IG+SN++     D L+ +K KPVVNQ E HPY  +  LV  C    + VTA++PLG         G    LDDP + G+A+ Y +T AQ+++RW IQR    I
Sbjct:  105 YLDLYLIHWPMAF---GRGDELIPRHPDGTIQYDDT-HYRDTWAAMEKLVDQGLAKAIGLSNFNAKQIDDILSIAKHKPVVNQVECHPYLVQAELVSHCWSRNLTVTAYSPLGSPDRPWVTPGEALLLDDPRVVGIAKSYNKTPAQVIIRWHIQRGVVCI 260          

HSP 2 Score: 99.3673 bits (246), Expect = 3.596e-50
Identity = 48/99 (48.48%), Postives = 66/99 (66.67%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQL 356
            ITL+ G +MP +GLG W+     ++  ++ A+  GYRHIDCAA Y NE EVGEAL E    G  ++R+D+F+T+KLWN+ H    V EAC+ SL  L+L
Sbjct:    5 ITLSTGQRMPTVGLGTWKSAPGQVKQAVLAALDCGYRHIDCAAAYSNEREVGEALTERLGPGKSLRRDDIFVTSKLWNTKHHPDDVEEACRRSLSDLRL 103          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: ALDR_RABIT (Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3)

HSP 1 Score: 121.709 bits (304), Expect = 1.764e-49
Identity = 70/162 (43.21%), Postives = 97/162 (59.88%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P   KH   G+    LDA G +    T  L+T W AME LV  GLV+SIG+SN++       L     K KP VNQ E HPY  ++ L+++C   GI VTA++PLG            S L+DP +K +A+K+K+T AQ+++R+ +QRN  VI
Sbjct:  104 YLDLYLIHWPTGFKH---GSEYFPLDAAGNVIPSDTDFLDT-WEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVVI 261          

HSP 2 Score: 95.9005 bits (237), Expect = 1.764e-49
Identity = 48/99 (48.48%), Postives = 63/99 (63.64%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSLKKLQLD 359
            + L NG KMPI+GLG W+     + + +  AI +GYRHIDCA  Y+NE EVG AL E     +VKRE+LFI +KLW + H    V  AC+ +L  L+LD
Sbjct:    5 LVLYNGAKMPILGLGTWKSPPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQEKLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLD 103          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1A1_CHICK (Alcohol dehydrogenase [NADP+] OS=Gallus gallus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 5.089e-49
Identity = 67/160 (41.88%), Postives = 93/160 (58.13%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P A +    G      + DG +  D T   + TW AME LV  GL ++IG+SN++     D L+ + VKP V Q E HPY  ++ L+  CQK G+ VTA++PLG      +       L++P +K LAEKYK++ AQI+LRW  QR    I
Sbjct:  108 YLDLYLMHWPHAFER---GDNLFPKNPDGTMRYDYT-DYKDTWKAMEKLVEKGLAKAIGLSNFNSRQIDDVLSVATVKPAVLQVECHPYLAQNELIAHCQKRGLVVTAYSPLGSPDRMWKHPDEPVLLEEPGIKKLAEKYKKSPAQILLRWQAQRKVVTI 263          

HSP 2 Score: 97.0561 bits (240), Expect = 5.089e-49
Identity = 45/100 (45.00%), Postives = 67/100 (67.00%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            + L NG K+P+IGLG W+ +   +++ +  A+ +GYRH+DCAA Y NEAE+G+A  E      ++KREDLF+T+KLWN+ H    V  A + +L  L+LD
Sbjct:    8 VALYNGQKIPLIGLGTWKSEPGQVKEAVKYALSVGYRHVDCAAAYSNEAEIGDAFQECVGPNKVIKREDLFVTSKLWNTKHHPEDVEPALRKTLADLKLD 107          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1A1_PIG (Alcohol dehydrogenase [NADP+] OS=Sus scrofa GN=AKR1A1 PE=1 SV=2)

HSP 1 Score: 120.939 bits (302), Expect = 8.646e-49
Identity = 66/160 (41.25%), Postives = 95/160 (59.38%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P A +    G      +ADG +  D T   + TW A+E LV+ GLVR++G+SN+      D L+ + V+P V Q E HPY  ++ L+  CQ  G+ VTA++PLG +            L++PV++ LAEKY R+ AQI+LRW +QR    I
Sbjct:  106 YLDLYLMHWPYAFER---GDNPFPKNADGTIRYDAT-HYKDTWKALEALVAKGLVRALGLSNFSSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPVVQALAEKYNRSPAQILLRWQVQRKVICI 261          

HSP 2 Score: 94.3597 bits (233), Expect = 8.646e-49
Identity = 48/100 (48.00%), Postives = 65/100 (65.00%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            + L+ G KMP+IGLG W+ +   ++  I  A+ +GYRHIDCAA Y NE E+GEAL E    G  V RE+LF+T+KLWN+ H    V  A + +L  LQL+
Sbjct:    6 VLLHTGQKMPLIGLGTWKSEPGQVKAAIKYALTVGYRHIDCAAIYGNELEIGEALTETVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLE 105          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: ALDR_PIG (Aldose reductase OS=Sus scrofa GN=AKR1B1 PE=1 SV=2)

HSP 1 Score: 120.553 bits (301), Expect = 1.127e-48
Identity = 68/162 (41.98%), Postives = 96/162 (59.26%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P   K    G     LD DG +  D +  +ET W AME+LV  GLV++IG+SN++       L     K KP VNQ E HPY  ++ L+++C+  GI VTA++PLG            S L+DP +K +A KY +T AQ+++R+ +QRN  VI
Sbjct:  104 YLDLYLIHWPTGFKP---GKDPFPLDGDGNVVPDESDFVET-WEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVI 261          

HSP 2 Score: 94.3597 bits (233), Expect = 1.127e-48
Identity = 48/99 (48.48%), Postives = 63/99 (63.64%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            + L  G KMPI+GLG W+     + + +  AI +GYRHIDCA  Y+NE EVG  L E     +VKREDLFI +KLW +DH    V  AC+ +L+ L+LD
Sbjct:    5 LVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQEKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLD 103          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: ALDR_HUMAN (Aldose reductase OS=Homo sapiens GN=AKR1B1 PE=1 SV=3)

HSP 1 Score: 117.087 bits (292), Expect = 1.469e-48
Identity = 71/166 (42.77%), Postives = 98/166 (59.04%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADG-VLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P   K    G     LD  G V+  DT I    TW AME+LV  GLV++IGISN+     ++ L +  L Y   KP VNQ E HPY  ++ L+++CQ  GI VTA++PLG            S L+DP +K +A K+ +T AQ+++R+ +QRN  VI
Sbjct:  104 YLDLYLIHWPTGFKP---GKEFFPLDESGNVVPSDTNIL--DTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKY---KPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVI 261          

HSP 2 Score: 97.4413 bits (241), Expect = 1.469e-48
Identity = 49/99 (49.49%), Postives = 65/99 (65.66%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            + LNNG KMPI+GLG W+     + + +  AI +GYRHIDCA  Y+NE EVG A+ E     +VKRE+LFI +KLW + H  G V  AC+ +L  L+LD
Sbjct:    5 LLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLD 103          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: XYL1_TRIRE (NAD(P)H-dependent D-xylose reductase OS=Trichoderma reesei GN=xyl1 PE=3 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 4.239e-48
Identity = 69/167 (41.32%), Postives = 90/167 (53.89%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTT-DSALDADGVLEI--DTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGA----VANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            Y DL+LVHFP A ++             DG  E+    T +L+ TW AME LV  GL RSIG+SNY      D L Y+++KP   Q E HPY Q+  LV   Q  GI VTA++  G      +           +D PV+K LA+K++RT AQ++LRW  QR  AVI
Sbjct:  105 YFDLFLVHFPAALEYVDPSVRYPPGWFYDGKSEVRWSKTTTLQQTWGAMERLVDKGLARSIGVSNYQAQSVYDALIYARIKPATLQIEHHPYLQQPDLVSLAQTEGIVVTAYSSFGPTGFMELDMPRAKSVAPLMDSPVIKALADKHRRTPAQVLLRWATQRGIAVI 271          

HSP 2 Score: 92.4337 bits (228), Expect = 4.239e-48
Identity = 42/80 (52.50%), Postives = 54/80 (67.50%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH 308
            + LN+G+ MP +G G+W++D +   D + NAIK GYR  D A DY NE E GE +A A   GLVKREDLFI +KLW + H
Sbjct:    6 LKLNSGYDMPQVGFGLWKVDNAVCADTVYNAIKAGYRLFDGACDYGNEKECGEGVARAIKDGLVKREDLFIVSKLWQTFH 85          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1A1_BOVIN (Alcohol dehydrogenase [NADP+] OS=Bos taurus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 4.239e-48
Identity = 65/160 (40.62%), Postives = 96/160 (60.00%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P A +    G +    +ADG +  D+T   ET W A+E LV+ GLVR++G+SN++     D L+ + V+P V Q E HPY  ++ L+  CQ   + VTA++PLG +            L +PV+  LAEK+ R+ AQI+LRW +QR  + I
Sbjct:  106 YLDLYLMHWPYAFER---GDSPFPKNADGTIRYDSTHYKET-WRALEALVAKGLVRALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCQARNLEVTAYSPLGSSDRAWRDPEEPVLLKEPVVLALAEKHGRSPAQILLRWQVQRKVSCI 261          

HSP 2 Score: 97.8265 bits (242), Expect = 4.239e-48
Identity = 51/100 (51.00%), Postives = 66/100 (66.00%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            I L+ G KMP+IGLG W+ D   ++  I  A+ +GYRHIDCAA Y NE E+GEAL E    G LV RE+LF+T+KLWN+ H    V  A + +L  LQL+
Sbjct:    6 ILLHTGQKMPLIGLGTWKSDPGQVKAAIKYALSVGYRHIDCAAIYGNETEIGEALKENVGPGKLVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLE 105          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 114.775 bits (286), Expect = 9.388e-48
Identity = 70/163 (42.94%), Postives = 93/163 (57.06%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADG-VLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            YLDLYL+H+P   K    G     LDA G V+  DT      TW AME LV  GLV++IG+SN++       L     K KP VNQ E HPY  ++ L+++C   GI VTA++PLG            S L+DP +K +A KY +T AQ+++R+ IQRN  VI
Sbjct:  104 YLDLYLIHWPTGFKP---GPDYFPLDASGNVIPSDT--DFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVI 261          

HSP 2 Score: 97.0561 bits (240), Expect = 9.388e-48
Identity = 49/99 (49.49%), Postives = 63/99 (63.64%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSLKKLQLD 359
            + LNNG KMP +GLG W+     + + +  AI +GYRHIDCA  Y+NE EVG AL E     +VKR+DLFI +KLW +  D   V  AC+ +L  LQLD
Sbjct:    5 LELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLD 103