EY753338

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_DICDI (Dihydropyrimidine dehydrogenase [NADP+] OS=Dictyostelium discoideum GN=pyd1 PE=2 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 2.199e-20
Identity = 57/161 (35.40%), Postives = 84/161 (52.17%), Query Frame = 2

Query:  251 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIGWENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLL 733
            D+S+ + G++ PNPF + S  P T+  +++R+F++GWG  V KT SLD   V NV+PR  R     +    GQ   + NI LIS++      K +   K    DR  +  +     K    +L    E +G D IE+N S  HGM E+ MG A GQ+  L+
Sbjct:  530 DISVEMCGMKFPNPFGLASATPATSAAMIRRSFEQGWGFAVTKTFSLDKDLVTNVSPRIVRGTTSGHHFGPGQ-GAFLNIELISEKTCHYWCKAIGELKRDFPDRIVIASIMCGFNKEDWTQLAKMAEASGADGIELNLSCPHGMGEKGMGLACGQDTELV 689          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_RAT (Dihydropyrimidine dehydrogenase [NADP+] OS=Rattus norvegicus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.872e-20
Identity = 61/177 (34.46%), Postives = 91/177 (51.41%), Query Frame = 2

Query:  251 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKFWGGIKQKL 766
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NI LIS++       ++   K    D   +  +  S  K    EL    E +G DA+E+N S  HGM ER MG A GQ+  L++     ++Q +
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKNDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQSV 702          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_PONAB (Dihydropyrimidine dehydrogenase [NADP+] OS=Pongo abelii GN=DPYD PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.872e-20
Identity = 65/194 (33.51%), Postives = 99/194 (51.03%), Query Frame = 2

Query:  230 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKFWGGIKQ 760
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NI LIS++      +++   K    D   +  +  S  K    EL  + E++G DA+E+N S  HGM ER MG A GQ+  L++     ++Q
Sbjct:  513 ASVSAKPELPLFYTAIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQ 700          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_MOUSE (Dihydropyrimidine dehydrogenase [NADP+] OS=Mus musculus GN=Dpyd PE=2 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.872e-20
Identity = 61/175 (34.86%), Postives = 90/175 (51.43%), Query Frame = 2

Query:  251 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKFWGGIKQ 760
            D+S+ + GL+ PNPF + S  P T+  +++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NI LIS++       ++   K    D   +  +  S  K    EL    E +G DA+E+N S  HGM ER MG A GQ+  L++     ++Q
Sbjct:  532 DISVEMAGLRFPNPFGLASATPATSTPMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPLYGPGQSSFLNIELISEKTAAYWCHSVTELKADFPDNILIASIMCSYNKSDWMELSKMAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQ 700          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_HUMAN (Dihydropyrimidine dehydrogenase [NADP+] OS=Homo sapiens GN=DPYD PE=1 SV=2)

HSP 1 Score: 98.9821 bits (245), Expect = 3.751e-20
Identity = 65/194 (33.51%), Postives = 99/194 (51.03%), Query Frame = 2

Query:  230 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKFWGGIKQ 760
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NI LIS++      +++   K    D   +  +  S  K    EL  + E++G DA+E+N S  HGM ER MG A GQ+  L++     ++Q
Sbjct:  513 ASVSAKPELPLFYTPIDLVDISVEMAGLKFINPFGLASATPATSTSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIIR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTELAKKSEDSGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQ 700          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_DANRE (Dihydropyrimidine dehydrogenase [NADP+] OS=Danio rerio GN=dpyd PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 8.356e-20
Identity = 58/167 (34.73%), Postives = 88/167 (52.69%), Query Frame = 2

Query:  251 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLK 736
            D+S+ + G++ PNPF + S PP T+  +++RAF++GWG  + KT  LD   V NV+PR  R      G+  G I G     + NI LIS++      K++   K        +  +  S  +    EL    +E+  DA+E+N S  HGM ER MG A GQ+  L++
Sbjct:  532 DISVEMCGIKFPNPFGLASAPPTTSAAMIRRAFEQGWGFALTKTFGLDKDLVTNVSPRIVR------GTTSGHIFGPGQGSFLNIELISEKTAAYWCKSVAELKADFPKNIIIASIMCSYNQADWTELAKMAQESQADALELNLSCPHGMGERGMGLACGQDPELVR 692          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_PIG (Dihydropyrimidine dehydrogenase [NADP+] OS=Sus scrofa GN=DPYD PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.425e-19
Identity = 65/194 (33.51%), Postives = 98/194 (50.52%), Query Frame = 2

Query:  230 ASASAEP------------DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKFWGGIKQ 760
            AS SA+P            D+S+ + GL+  NPF + S  P T+ ++++RAF+ GWG  + KT SLD   V NV+PR  R      G+  G + G     + NI LIS++      +++   K    D   +  +  S  K    EL  + E +G DA+E+N S  HGM ER MG A GQ+  L++     ++Q
Sbjct:  513 ASVSAKPELPLFYTPVDLVDISVEMAGLKFINPFGLASAAPTTSSSMIRRAFEAGWGFALTKTFSLDKDIVTNVSPRIVR------GTTSGPMYGPGQSSFLNIELISEKTAAYWCQSVTELKADFPDNIVIASIMCSYNKNDWMELSRKAEASGADALELNLSCPHGMGERGMGLACGQDPELVRNICRWVRQ 700          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_CAEEL (Dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis elegans GN=dpyd-1 PE=2 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 1.861e-19
Identity = 66/203 (32.51%), Postives = 101/203 (49.75%), Query Frame = 2

Query:  245 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKF--WGGIKQKLLFLVGQRDS*HTDLTRVALAKR 832
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NI LIS++  E   + +   K     +  +  +     K    EL  + EE G D +E+N S  HGM E+ MG A GQ+  ++K+   W     K+ F      +  TD+  +A A R
Sbjct:  544 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVIASIMCVYNKADWIELATKSEEAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPN-ITDVREIARAAR 739          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: DPYD_CAEBR (Probable dihydropyrimidine dehydrogenase [NADP+] OS=Caenorhabditis briggsae GN=dpyd-1 PE=3 SV=2)

HSP 1 Score: 93.2041 bits (230), Expect = 2.058e-18
Identity = 65/203 (32.02%), Postives = 100/203 (49.26%), Query Frame = 2

Query:  245 EPDLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIG-----WENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKF--WGGIKQKLLFLVGQRDS*HTDLTRVALAKR 832
            E D+S+ + G++  NPF + S PP T+  + +RAF++GWG ++ KT  LD   V NV+PR  R      GS  G + G     + NI LIS++  E   + +   K     +  +  +     K    EL  + E  G D +E+N S  HGM E+ MG A GQ+  ++K+   W     K+ F      +  TD+  +A A R
Sbjct:  554 EVDISVDMCGVKFENPFGLASAPPTTSGPMCRRAFEQGWGFILTKTYGLDKDLVTNVSPRIVR------GSTSGPLYGPNQGSFMNIELISEKSCEYWLQCIRELKRDHPTKIVVASIMCVYNKEDWIELATKSEAAGADILELNLSCPHGMGEKGMGLACGQSPEIVKEICRWVRACVKIPFFPKMTPN-ITDVREIARAAR 749          

BLAST of EY753338 vs. ExPASy Swiss-Prot
Match: YEIA_ECOLI (Uncharacterized protein yeiA OS=Escherichia coli (strain K12) GN=yeiA PE=3 SV=3)

HSP 1 Score: 92.0485 bits (227), Expect = 4.585e-18
Identity = 66/196 (33.67%), Postives = 99/196 (50.51%), Query Frame = 2

Query:  251 DLSITVNGLQMPNPFVIGSGPPGTNYTVMKRAFDEGWGAVVAKTVSLDAAKVINVTPRYARLRAGANGSAKGQIIGWENIXLISDRPLEQC*KNLNN*KHCIRDRFSLLQLWKSITKLHGEELIDRVEETGIDAIEVNFSWSHGMPERKMGAAVGQNCRLLKKFWGGIKQ-KLLFLVGQRDS*HTDLTRVALAKRK 835
            DLSIT  G++ PNPF + S P G  Y +  +A+D GWG VV KT+    A    V+PR+  L     G      IG++N+  I++ PLE+    L   K    D+  +  +     +   EEL   V+E G D IE NFS    M    MG+ VGQ+  L++K+   +K+   L ++ +      D+  VALA ++
Sbjct:    5 DLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGVVFKTIGFFIAN--EVSPRFDHLVKEDTG-----FIGFKNMEQIAEHPLEENLAALRRLKEDYPDKVLIASIMGE-NEQQWEELARLVQEAGADMIECNFSCPQ-MTSHAMGSDVGQSPELVEKYCRAVKRGSTLPMLAKMTPNIGDMCEVALAAKR 191