EY688437

BLAST of EY688437 vs. ExPASy Swiss-Prot
Match: TYDP1_HUMAN (Tyrosyl-DNA phosphodiesterase 1 OS=Homo sapiens GN=TDP1 PE=1 SV=2)

HSP 1 Score: 110.923 bits (276), Expect = 8.001e-30
Identity = 65/132 (49.24%), Postives = 87/132 (65.91%), Query Frame = 3

Query:  186 VLLQFSSLGSL---DEKWM-AELXXXXXXXXXEDKTPLGIGEPL-IVWPTVEDVRCSLEGYAAGNAIPSPQKNVDK-DFLKKYWAKWKASHTGRSRAMPHIKTFARYNGQ--KLAWFLLTSANLSKAAWGAL 557
            V+ QFSS+GSL   + KW+ +E          E KTP     PL +++P+VE+VR SLEGY AG ++P   +  +K ++L  Y+ KW A  +GRS AMPHIKT+ R +    K+AWFL+TSANLSKAAWGAL
Sbjct:  394 VVGQFSSVGSLGADESKWLCSEFKESMLTLGKESKTPGKSSVPLYLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQNWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKIAWFLVTSANLSKAAWGAL 525          

HSP 2 Score: 39.2762 bits (90), Expect = 8.001e-30
Identity = 18/22 (81.82%), Postives = 20/22 (90.91%), Query Frame = 1

Query:  559 QKNNSQLMIRSYELGVLILPSA 624
            +KN +QLMIRSYELGVL LPSA
Sbjct:  526 EKNGTQLMIRSYELGVLFLPSA 547          

BLAST of EY688437 vs. ExPASy Swiss-Prot
Match: TYDP1_RAT (Tyrosyl-DNA phosphodiesterase 1 OS=Rattus norvegicus GN=Tdp1 PE=2 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 2.299e-29
Identity = 65/132 (49.24%), Postives = 86/132 (65.15%), Query Frame = 3

Query:  186 VLLQFSSLGSL---DEKWM-AELXXXXXXXXXEDKTPLGIGEPL-IVWPTVEDVRCSLEGYAAGNAIPSPQKNVDKD-FLKKYWAKWKASHTGRSRAMPHIKTFARYNGQ--KLAWFLLTSANLSKAAWGAL 557
            V+ QFSS+GSL   + KW+ +E          E +TP     PL +++P+VE+VR SLEGY AG ++P   +  +K  +L  Y+ KW A  +GRS AMPHIKT+ R +    KLAWFL+TSANLSKAAWGAL
Sbjct:  395 VVGQFSSIGSLGPDESKWLCSEFKESLLAVREEGRTPGRSAVPLHLIYPSVENVRTSLEGYPAGGSLPYGIQTAEKQRWLHPYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKLAWFLVTSANLSKAAWGAL 526          

HSP 2 Score: 39.2762 bits (90), Expect = 2.299e-29
Identity = 18/22 (81.82%), Postives = 20/22 (90.91%), Query Frame = 1

Query:  559 QKNNSQLMIRSYELGVLILPSA 624
            +KN +QLMIRSYELGVL LPSA
Sbjct:  527 EKNGAQLMIRSYELGVLFLPSA 548          

BLAST of EY688437 vs. ExPASy Swiss-Prot
Match: TYDP1_MOUSE (Tyrosyl-DNA phosphodiesterase 1 OS=Mus musculus GN=Tdp1 PE=2 SV=2)

HSP 1 Score: 107.457 bits (267), Expect = 8.600e-29
Identity = 63/129 (48.84%), Postives = 83/129 (64.34%), Query Frame = 3

Query:  195 QFSSLGSL---DEKWM-AELXXXXXXXXXEDKTPLGIGEPL-IVWPTVEDVRCSLEGYAAGNAIPSPQKNVDKD-FLKKYWAKWKASHTGRSRAMPHIKTFARYNGQ--KLAWFLLTSANLSKAAWGAL 557
            QFSS+GSL   + KW+ +E          E + P     PL +++P+VE+VR SLEGY AG ++P   +  +K  +L  Y+ KW A  +GRS AMPHIKT+ R +    KLAWFL+TSANLSKAAWGAL
Sbjct:  398 QFSSIGSLGPDESKWLCSEFKDSLLALREEGRPPGKSAVPLHLIYPSVENVRTSLEGYPAGGSLPYSIQTAEKQRWLHSYFHKWSAETSGRSNAMPHIKTYMRPSPDFSKLAWFLVTSANLSKAAWGAL 526          

HSP 2 Score: 39.2762 bits (90), Expect = 8.600e-29
Identity = 18/22 (81.82%), Postives = 20/22 (90.91%), Query Frame = 1

Query:  559 QKNNSQLMIRSYELGVLILPSA 624
            +KN +QLMIRSYELGVL LPSA
Sbjct:  527 EKNGTQLMIRSYELGVLFLPSA 548          

BLAST of EY688437 vs. ExPASy Swiss-Prot
Match: TYDP1_DROME (Probable tyrosyl-DNA phosphodiesterase OS=Drosophila melanogaster GN=gkt PE=2 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 1.055e-17
Identity = 52/131 (39.69%), Postives = 75/131 (57.25%), Query Frame = 3

Query:  180 LDVLLQFSSLGSLDEKWMAELXXXXXXXXXEDKTPLGIGEPL----IVWPTVEDVRCSLEGYAAGNAIPSPQKNVDKD-FLKKYWAKWKASHTGRSRAMPHIKTFARYN--GQKLAWFLLTSANLSKAAWG 551
            + V+ Q SS+GSL     A +         +D TP+G    +    +++P+  +V  S +G   G  +P  +   DK  +LK Y  +WK+S   RSRAMPHIK++ R+N   Q + WF+LTSANLSKAAWG
Sbjct:  379 IPVVCQSSSIGSLGANVQAWIQQDFVNSLKKDSTPVGKLRQMPPFKMIYPSYGNVAGSHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSDRFRSRAMPHIKSYTRFNLEDQSVYWFVLTSANLSKAAWG 509          

HSP 2 Score: 21.1718 bits (43), Expect = 1.055e-17
Identity = 9/14 (64.29%), Postives = 10/14 (71.43%), Query Frame = 1

Query:  577 LMIRSYELGVLILP 618
            L I +YE GVL LP
Sbjct:  521 LRIANYEAGVLFLP 534          

BLAST of EY688437 vs. ExPASy Swiss-Prot
Match: TYDP1_CAEEL (Probable tyrosyl-DNA phosphodiesterase OS=Caenorhabditis elegans GN=F52C12.1 PE=2 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 8.655e-17
Identity = 37/83 (44.58%), Postives = 56/83 (67.47%), Query Frame = 3

Query:  306 IVWPTVEDVRCSLEGYAAGNAIPSPQK-NVDKDFLKKYWAKWKASHTGRSRAMPHIKTFARYNGQKLAWFLLTSANLSKAAWG 551
            +V+P+VEDVR S +GYA G ++P     +  + +L+    KW+++   R+ A+PH KT+ +Y+ +   W LLTSANLSKAAWG
Sbjct:  302 LVFPSVEDVRTSCQGYAGGCSVPYRNSVHARQKWLQGNMCKWRSNAKRRTNAVPHCKTYVKYDKKVAIWQLLTSANLSKAAWG 384          

HSP 2 Score: 28.8758 bits (63), Expect = 8.655e-17
Identity = 13/20 (65.00%), Postives = 16/20 (80.00%), Query Frame = 1

Query:  553 HSQKNNSQLMIRSYELGVLI 612
            +  KN  QLMIRS+E+GVLI
Sbjct:  389 NKSKNVEQLMIRSWEMGVLI 408          

BLAST of EY688437 vs. ExPASy Swiss-Prot
Match: TYDP1_SCHPO (Probable tyrosyl-DNA phosphodiesterase OS=Schizosaccharomyces pombe GN=SPCP31B10.05 PE=2 SV=1)

HSP 1 Score: 67.0106 bits (162), Expect = 1.803e-12
Identity = 48/131 (36.64%), Postives = 68/131 (51.91%), Query Frame = 3

Query:  195 QFSSLGSLDEK--WMAELXXXXXXXXXEDKTPLGIGEPLIVWPTVEDVRCSLEGYAAGNAI------PSPQKNVDKDFLKKYWAKWKASHTGRSRAMPHIKTFARYN--GQKLAWFLLTSANLSKAAWGAL 557
            Q SS+GS   K  ++AEL          D      G    ++PTV++V+ S+ G+ +G++I       +    V+     K   KW A   GR R  PHIKT+ R++  G+ L W L+TSANLSK AWG L
Sbjct:  312 QCSSMGSFGPKQEYIAELT---------DGFGCQRGNWKFLFPTVKEVQQSMLGWQSGSSIHFNILGKTAASQVETLKKGKNLCKWVAMKAGRQRVAPHIKTYMRFSNDGELLRWVLVTSANLSKPAWGTL 433          

HSP 2 Score: 24.6386 bits (52), Expect = 1.803e-12
Identity = 13/24 (54.17%), Postives = 15/24 (62.50%), Query Frame = 1

Query:  553 HSQKNNSQ--LMIRSYELGVLILP 618
            H  K+ S   L IRSYE GVL+ P
Sbjct:  436 HKAKSRSTRGLRIRSYEAGVLLYP 459