EY685039

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_ARATH (DNA topoisomerase 1 OS=Arabidopsis thaliana GN=TOP1 PE=1 SV=1)

HSP 1 Score: 329.331 bits (843), Expect = 2.051e-89
Identity = 165/209 (78.95%), Postives = 187/209 (89.47%), Query Frame = 1

Query:    1 QNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 627
            + DDLFD+LDT+KLNAHLKEL+PGLTAKVFRTYNASITLD ML++ T DGDV  KI VYQ+ANKEVAIICNHQRTVSKTH AQ+ +LT +IE+LK VLK+L+ +LDRAKKGKPPL + SDGK+ R+L P A E+K+AQ +AKIEKMERDM TKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIF KSLL KFAWAMDV+PE+RF
Sbjct:  706 KTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLDEMLSQETKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTHGAQIEKLTARIEELKEVLKELKTNLDRAKKGKPPL-EGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMDVEPEYRF 913          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_DAUCA (DNA topoisomerase 1 OS=Daucus carota GN=TOP1 PE=2 SV=1)

HSP 1 Score: 305.834 bits (782), Expect = 2.428e-82
Identity = 166/234 (70.94%), Postives = 184/234 (78.63%), Query Frame = 1

Query:    7 DDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGM-----LNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPE----------------------ALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDVDPEFRF 627
            DDLFD+LDT+KLNAHLKELMPGLTAKVFRTYNASITLD M     L++ T  GDVA K+ VYQ ANKEVAIICNHQRTVSK+HSAQM RL EKIE+LKG+LK+L+ DL R  KGKPPL K+SDGK KRNL  +                      ++ +K+AQTN KIEKMERD +TKEDLKTVALGTSKINYLDPRITVAWCKRH+VPIEKIFNKSLLAKFAWAMDV   FRF
Sbjct:  558 DDLFDQLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMVRCKLLSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMVRLNEKIEELKGLLKELQEDLTRVNKGKPPL-KNSDGKPKRNLNLKRYKGKLLKLIQKLRKWSETRRLSVTKKIAQTNTKIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAMDVVLIFRF 790          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_RAT (DNA topoisomerase 1 OS=Rattus norvegicus GN=Top1 PE=2 SV=1)

HSP 1 Score: 185.652 bits (470), Expect = 3.662e-46
Identity = 107/209 (51.20%), Postives = 135/209 (64.59%), Query Frame = 1

Query:    7 DDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDV-DPEFRF 627
            DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+   KFAWA+D+ D ++ F
Sbjct:  564 DDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_MOUSE (DNA topoisomerase 1 OS=Mus musculus GN=Top1 PE=1 SV=2)

HSP 1 Score: 185.267 bits (469), Expect = 4.782e-46
Identity = 107/209 (51.20%), Postives = 135/209 (64.59%), Query Frame = 1

Query:    7 DDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDV-DPEFRF 627
            DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+   KFAWA+D+ D ++ F
Sbjct:  564 DDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_CRIGR (DNA topoisomerase 1 OS=Cricetulus griseus GN=TOP1 PE=2 SV=1)

HSP 1 Score: 185.267 bits (469), Expect = 4.782e-46
Identity = 107/209 (51.20%), Postives = 135/209 (64.59%), Query Frame = 1

Query:    7 DDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDV-DPEFRF 627
            DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+   KFAWA+D+ D ++ F
Sbjct:  564 DDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_CERAE (DNA topoisomerase 1 OS=Cercopithecus aethiops GN=TOP1 PE=2 SV=1)

HSP 1 Score: 184.496 bits (467), Expect = 8.158e-46
Identity = 106/209 (50.72%), Postives = 135/209 (64.59%), Query Frame = 1

Query:    7 DDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDV-DPEFRF 627
            DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D ++  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+   KFAWA+D+ D ++ F
Sbjct:  564 DDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_HUMAN (DNA topoisomerase 1 OS=Homo sapiens GN=TOP1 PE=1 SV=2)

HSP 1 Score: 184.111 bits (466), Expect = 1.065e-45
Identity = 106/209 (50.72%), Postives = 135/209 (64.59%), Query Frame = 1

Query:    7 DDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDV-DPEFRF 627
            DDLFD+L+T  LN HL++LM GLTAKVFRTYNASITL   L + T  D ++  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R DL  AK     +MKD+  K+      +A++R   Q    + K+E     +E+ K +ALGTSK+NYLDPRITVAWCK+  VPIEKI+NK+   KFAWA+D+ D ++ F
Sbjct:  562 DDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDLKSAK-ADAKVMKDAKTKKVVESKKKAVQRLEEQ----LMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_CAEEL (DNA topoisomerase 1 OS=Caenorhabditis elegans GN=top-1 PE=2 SV=1)

HSP 1 Score: 181.8 bits (460), Expect = 5.288e-45
Identity = 101/213 (47.42%), Postives = 132/213 (61.97%), Query Frame = 1

Query:    4 NDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGD-VAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDV----DPEFRF 627
            +DDLFD+LDTA LN HL+ LM GLT KVFRTYNASITL   L K T   D VA KI  Y RAN++VAI+CNHQR VSK     M +L +KI+D K  +K+    L                K  R    E  ++K  +   +++K++     K++ K +ALGTSK+NY+DPRITVAWCK+ EVP+EK+F K+   KF WA+D+    D E+ F
Sbjct:  610 SDDLFDRLDTATLNDHLRSLMDGLTVKVFRTYNASITLQEQLIKLTNPKDNVAAKILSYNRANRQVAILCNHQRAVSKGFDESMQKLEQKIKDKKKEVKEAEAAL----------------KSARGAEKEKAQKKYDRLKEQLKKLKISRTDKDENKQIALGTSKLNYIDPRITVAWCKKFEVPLEKVFTKTHREKFRWAIDMTNSSDEEYVF 806          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1_DROME (DNA topoisomerase 1 OS=Drosophila melanogaster GN=Top1 PE=1 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.440e-42
Identity = 101/213 (47.42%), Postives = 130/213 (61.03%), Query Frame = 1

Query:    1 QNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRA--KKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMDV-DPEFRF 627
            + DDLFD+L+T  LN HLKELM GLTAKVFRTYNAS TL   L+  T     V  K+  Y RAN+ VAI+CNHQR+V K+H   M  L EKI+  +  ++    +      KKGK                   LER   Q    ++K+E     +++ KT+ALGTSK+NYLDPRI+VAWCK+H+VPIEKIFNK+   KF WA+ + D  +RF
Sbjct:  782 EGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRDEKKGKQ------------------LERLRDQ----LKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 972          

BLAST of EY685039 vs. ExPASy Swiss-Prot
Match: TOP1M_MOUSE (DNA topoisomerase I, mitochondrial OS=Mus musculus GN=Top1mt PE=2 SV=1)

HSP 1 Score: 172.17 bits (435), Expect = 4.190e-42
Identity = 93/201 (46.27%), Postives = 127/201 (63.18%), Query Frame = 1

Query:    7 DDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAQTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPIEKIFNKSLLAKFAWAMD 606
            DDLFD L T+ LN HL++LM GLTAKVFRTYNAS+TL   L   T  +  V  K+  Y RAN+ VA++CNHQR V KT    M  L +KIE  K  + + +V+L +A+     L    D K K  L  +   R++ +   ++ ++      KE+ K VALGT+K+NYLDPRI++AWCKR  VP+EKI+NK+   +FAWA +
Sbjct:  391 DDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKKAQVAEAQVELQKAETD---LRMRGDSKPKSFLQKQ---RRLLKLEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPVEKIYNKTQRERFAWAFN 585