EY660133

BLAST of EY660133 vs. ExPASy Swiss-Prot
Match: NICA_ARATH (Nicastrin OS=Arabidopsis thaliana GN=At3g52640/At3g52650 PE=2 SV=1)

HSP 1 Score: 290.041 bits (741), Expect = 1.193e-77
Identity = 152/270 (56.30%), Postives = 185/270 (68.52%), Query Frame = 3

Query:   12 QKFPQAEFAPYPSINYEWNSMGSGIMLKAYDFPVFLLSESSTSMLQEVADKNEKVMNGYTTSVAEFDLVMQTTKAGTHDSESCLKEQTCLPLGGYSVWSSLPPINMSLSYQSKPIILLVASMDSASFFRDKSLGADSPIXXXXXXXXXXXXXXRVDGWNDLNKQLVFLVLTGEAWGYLGSRRFLHELDMQSDGVSGLNSSLIEMVLEIXXXXXXXXXXXXTFFTHTTGVSSAXNDALDAXKRAQVHLNLKTLKSYRL-ILKSWDPPSSLM 818
            ++FPQA+F+PY ++ Y+WNS  S IM + Y+FPV+LLSES  S + E+  K +     YT+ VAEF++VM+TTKAGTH+SE+CL+E TCLPLGGYSVWSSLPPI++S S   KP++L VASMD+ASFFRDKS GADSPI              RVDG ++L KQLVFLVLTGE WGYLGSRRFLHELD+ SD V+GL+++ IE VLEI            TFF H T VSS  N  LDA K AQ  L  K +K           PPSSLM
Sbjct:  138 KRFPQAQFSPYENVEYKWNSAASSIMWRNYNFPVYLLSESGISAVHEILSKKKMKHGTYTSDVAEFNMVMETTKAGTHNSEACLQEGTCLPLGGYSVWSSLPPISVSSSNNRKPVVLTVASMDTASFFRDKSFGADSPISGLVALLGAVDALSRVDGISNLKKQLVFLVLTGETWGYLGSRRFLHELDLHSDAVAGLSNTSIETVLEIGSVGKGLSGGINTFFAHKTRVSSVTNMTLDALKIAQDSLASKNIKILSADTANPGIPPSSLM 407          

BLAST of EY660133 vs. ExPASy Swiss-Prot
Match: NICA_DICDI (Nicastrin OS=Dictyostelium discoideum GN=ncstn PE=3 SV=2)

HSP 1 Score: 97.4413 bits (241), Expect = 1.135e-19
Identity = 58/186 (31.18%), Postives = 92/186 (49.46%), Query Frame = 3

Query:   15 KFPQAEFAPYPSINYEWNSMGSGIMLKAYDFPVFLLSESSTSMLQEVADKNEKVMNGYTTSVAEFDLVMQTTKAGTHDSESCLKEQTCLPLGGYSVWSSLPPINMSLSYQSKPIILLVASMDSASFFRDKSLGADSPIXXXXXXXXXXXXXXRVDGWNDLNKQLVFLVLTGEAWGYLGSRRFLHEL 572
            ++P  +F  YP  N  WN  G G     + FP+F L   ++ +++ ++  N      Y    AE D  MQ    G  ++E+CL+   C P+GG S+WSS   +      QSKPIIL++  +D+ +FFRD + G D                  VD     +K+++F +   E WGY+GS  F+++L
Sbjct:  127 QYPIKQFGLYPDSNLNWNPNGDGFTYMNFPFPMFALELKTSIIIRNLSTINRD--GKYPAYGAELDSFMQ----GAINAETCLRRGFCEPVGGQSIWSSFSEV----IDQSKPIILVMLPIDATAFFRDLATGTDQSGYALTVLLSMLNTLQGVDK-TKWDKEVIFAMWNSERWGYVGSTNFVNDL 301          

BLAST of EY660133 vs. ExPASy Swiss-Prot
Match: NICA_MOUSE (Nicastrin OS=Mus musculus GN=Ncstn PE=1 SV=2)

HSP 1 Score: 75.8702 bits (185), Expect = 3.537e-13
Identity = 45/185 (24.32%), Postives = 89/185 (48.11%), Query Frame = 3

Query:   63 WNSMGSGIMLKAYDFPVFLLS-ESSTSMLQEVADKNEKVMNGYTTSVAEFDLVMQTTKAGTHDSESCLK------------EQTCLPLGGYSVWSSLPPINMSLSYQSKPIILLVAS-MDSASFFRDKSLGADSPIXXXXXXXXXXXXXXRVDGWNDLNKQLVFLVLTGEAWGYLGSRRFLHELD 575
            WN +G+G+  + + FP+FLL  E+ T ++++    +    NG   S     + + +       + +C++            E  C PL  Y+VWS L PIN S+  +    +++ A+ +DS SFF + + GA+S +              +      L++ ++F+   GE + Y+GS R +++++
Sbjct:  163 WNELGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLGQNGSAPSFPLCAMQLFSHMHAVISTATCMRRSFIQSTFSINPEIVCDPLSDYNVWSMLKPINTSVGLEPDVRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALHKAPDVTTLSRNVMFVFFQGETFDYIGSSRMVYDME 347          

BLAST of EY660133 vs. ExPASy Swiss-Prot
Match: NICA_HUMAN (Nicastrin OS=Homo sapiens GN=NCSTN PE=1 SV=2)

HSP 1 Score: 73.9442 bits (180), Expect = 1.344e-12
Identity = 48/189 (25.40%), Postives = 91/189 (48.15%), Query Frame = 3

Query:   60 EWNSMGSGIMLKAYDFPVFLL-SESSTSMLQEVADKNEKVMNGYTTSVAEFDLVMQTTKAGTH---DSESCLK------------EQTCLPLGGYSVWSSLPPINMSLSYQSKPIILLVAS-MDSASFFRDKSLGADSPIXXXXXXXXXXXXXXRVDGWNDLNKQLVFLVLTGEAWGYLGSRRFLHELD 575
            +WNS+G+G+  + + FP+FLL  E+ T ++++    +    NG   S   F L      +  H    + +C++            E  C PL  Y+VWS L PIN + + +    +++ A+ +DS SFF + + GA+S +              +      L + ++F+   GE + Y+GS R +++++
Sbjct:  163 QWNSLGNGLAYEDFSFPIFLLEDENETKVIKQCYQDHNLSQNG---SAPTFPLCAMQLFSHMHAVISTATCMRRSSIQSTFSINPEIVCDPLSDYNVWSMLKPINTTGTLKPDDRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALQKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDME 348          

BLAST of EY660133 vs. ExPASy Swiss-Prot
Match: NICA_RAT (Nicastrin OS=Rattus norvegicus GN=Ncstn PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.107e-12
Identity = 45/185 (24.32%), Postives = 86/185 (46.49%), Query Frame = 3

Query:   63 WNSMGSGIMLKAYDFPVFLLS-ESSTSMLQEVADKNEKVMNGYTTSVAEFDLVMQTTKAGTHDSESCLK------------EQTCLPLGGYSVWSSLPPINMSLSYQSKPIILLVAS-MDSASFFRDKSLGADSPIXXXXXXXXXXXXXXRVDGWNDLNKQLVFLVLTGEAWGYLGSRRFLHELD 575
            WN +G+G+    + FP+FLL  E+ T ++++    +    NG   S     + + +       + +C++            E  C PL  Y+VWS L PIN S   +    +++ A+ +DS SFF + + GA+S +              +      L + ++F+   GE + Y+GS R +++++
Sbjct:  163 WNELGNGLAYDDFSFPIFLLEDENETKVIKQCYQDHNLGQNGSAPSFPLCAMQLFSHMHAVISTATCMRRSFIQSTFSINPEIVCDPLSDYNVWSMLKPINTSGGLEPDVRVVVAATRLDSRSFFWNVAPGAESAVASFVTQLAAAEALHKAPDVTTLPRNVMFVFFQGETFDYIGSSRMVYDME 347