EY674160

BLAST of EY674160 vs. ExPASy Swiss-Prot
Match: FYV1_HUMAN (1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo sapiens GN=PIKFYVE PE=1 SV=2)

HSP 1 Score: 73.9442 bits (180), Expect = 2.958e-17
Identity = 44/133 (33.08%), Postives = 70/133 (52.63%), Query Frame = 2

Query:   50 LQRVREDEFASFDKFALHYFKHMNESFDSGNQTCLAKVLGIYQGTIKQPKSGKEMRHDLMVMDNLTFERNITRQYDLKRALHARYNTTVDGSGD---VLLDQNFCNDMNSSPLYVSITA*LILHTNCLQ*HHF 439
            L+++   E  SF  FA HYF ++  +      T LAK+LG+Y+   K  ++  E + DL+VM+NL + R + + +DLK +L  R   T  G      VLLD+N    +  +PLY+   +  +L T+     HF
Sbjct: 1876 LKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHF 2008          

HSP 2 Score: 36.1946 bits (82), Expect = 2.958e-17
Identity = 21/39 (53.85%), Postives = 24/39 (61.54%), Query Frame = 1

Query:  460 MDYSLLVGCAYSAAGSLVCGIIDYLRLIPGDKHLETWVK 576
            +DYSLLVG     +  LV GIIDY+R    DK LE  VK
Sbjct: 2015 IDYSLLVG-RDDTSNELVVGIIDYIRTFTWDKKLEMVVK 2052          

BLAST of EY674160 vs. ExPASy Swiss-Prot
Match: FYV1_MOUSE (1-phosphatidylinositol-3-phosphate 5-kinase OS=Mus musculus GN=Pikfyve PE=1 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 4.997e-17
Identity = 44/133 (33.08%), Postives = 70/133 (52.63%), Query Frame = 2

Query:   50 LQRVREDEFASFDKFALHYFKHMNESFDSGNQTCLAKVLGIYQGTIKQPKSGKEMRHDLMVMDNLTFERNITRQYDLKRALHARYNTTVDGSGD---VLLDQNFCNDMNSSPLYVSITA*LILHTNCLQ*HHF 439
            L+++   E  SF  FA HYF ++  +      T LAK+LG+Y+   K  ++  E + DL+VM+NL + R + + +DLK +L  R   T  G      VLLD+N    +  +PLY+   +  +L T+     HF
Sbjct: 1875 LKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDNPLYIRSHSKSVLRTSIHSDAHF 2007          

HSP 2 Score: 36.1946 bits (82), Expect = 4.997e-17
Identity = 21/39 (53.85%), Postives = 24/39 (61.54%), Query Frame = 1

Query:  460 MDYSLLVGCAYSAAGSLVCGIIDYLRLIPGDKHLETWVK 576
            +DYSLLVG     +  LV GIIDY+R    DK LE  VK
Sbjct: 2014 IDYSLLVG-RDDTSNELVVGIIDYIRTFTWDKKLEMVVK 2051          

BLAST of EY674160 vs. ExPASy Swiss-Prot
Match: FAB1_YEAST (1-phosphatidylinositol-3-phosphate 5-kinase FAB1 OS=Saccharomyces cerevisiae GN=FAB1 PE=1 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 6.484e-17
Identity = 38/113 (33.63%), Postives = 64/113 (56.64%), Query Frame = 2

Query:   50 LQRVREDEFASFDKFALHYFKHMNESFDSGNQTCLAKVLGIYQGTIKQP-KSGKEMRHDLMVMDNLTFERNITRQYDLKRALHARYNTTVDGSGDVLLDQNFCNDMNSSPLYV 385
            ++ +   E  +F KFA  YF++M ++      T LAKV G YQ  +K    S K  + D+++M+NL +E+  TR +DLK ++  R+      + +VLLD+N    +  SP++V
Sbjct: 2058 IKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQIQVKSSISSSKSYKMDVIIMENLFYEKKTTRIFDLKGSMRNRHVEQTGKANEVLLDENMVEYIYESPIHV 2170          

HSP 2 Score: 38.5058 bits (88), Expect = 6.484e-17
Identity = 19/39 (48.72%), Postives = 26/39 (66.67%), Query Frame = 1

Query:  460 MDYSLLVGCAYSAAGSLVCGIIDYLRLIPGDKHLETWVK 576
            MDYSL++G   +   +L  GIID++R    DK LE+WVK
Sbjct: 2195 MDYSLVIGID-NEGYTLTVGIIDFIRTFTWDKKLESWVK 2232          

BLAST of EY674160 vs. ExPASy Swiss-Prot
Match: FAB1_SCHPO (1-phosphatidylinositol-3-phosphate 5-kinase fab1 OS=Schizosaccharomyces pombe GN=fab1 PE=2 SV=2)

HSP 1 Score: 64.3142 bits (155), Expect = 3.135e-16
Identity = 38/125 (30.40%), Postives = 68/125 (54.40%), Query Frame = 2

Query:   50 LQRVREDEFASFDKFALHYFKHMNESFDSGNQTCLAKVLGIYQGTIKQPKSGKEMRHDLMVMDNLTFERNITRQYDLKRALHARYNTTVDGSGDVLLDQNFCNDMNSSPLYVSITA*LILHTNCL 424
            L R+  D   +F   A  YF ++++ F     T L K+ G Y+  I+ P +G   + D+M+M+N+ ++   +R +DLK ++  R+  +     +VLLD+N    +  SP++VS     +LH +CL
Sbjct: 1715 LSRLESDSLLNF---APAYFDYISKVFFHELPTALTKIFGFYRVDIRNPTTGTICKTDIMIMENVFYDECPSRIFDLKGSMRNRHVESTGKVDEVLLDENLVELIYESPIFVSEQLKSLLH-SCL 1835          

HSP 2 Score: 42.3578 bits (98), Expect = 3.135e-16
Identity = 23/47 (48.94%), Postives = 30/47 (63.83%), Query Frame = 1

Query:  436 LSLNLTHEMDYSLLVGCAYSAAGSLVCGIIDYLRLIPGDKHLETWVK 576
            L L+  + MDYSL+VG  Y+    L  GIID++R    DK LE+WVK
Sbjct: 1840 LFLSKLNIMDYSLIVGIDYTKK-ELYVGIIDFIRTYTWDKKLESWVK 1885          

BLAST of EY674160 vs. ExPASy Swiss-Prot
Match: FYV1_DICDI (1-phosphatidylinositol-3-phosphate 5-kinase OS=Dictyostelium discoideum GN=pip5k3 PE=3 SV=1)

HSP 1 Score: 63.929 bits (154), Expect = 4.499e-14
Identity = 40/110 (36.36%), Postives = 63/110 (57.27%), Query Frame = 2

Query:   50 LQRVREDEFASFDKFALHYFKHMNESFDSGNQTCLAKVLGIYQGTIKQPKSGKEMRHDLMVMDNLTFERNITRQYDLKRALHARYNTTVDGSGDVLLDQNFCNDMNSSPL 379
            L++V   E  SF  FA  YF+++ +SF +   T L K+LG++    K   +GK ++ DL+VM+NL   + I++ YDLK +L  R    V    +VLLD+N      +SP+
Sbjct: 2395 LKQVSRIELESFLDFAPLYFEYICKSFLNQIPTALCKILGVFTVRWKD-SNGKALKKDLIVMENLFHSKCISKTYDLKGSLRGR---LVKNESEVLLDENLLQASFASPI 2500          

HSP 2 Score: 35.4242 bits (80), Expect = 4.499e-14
Identity = 22/45 (48.89%), Postives = 27/45 (60.00%), Query Frame = 1

Query:  442 LNLTHEMDYSLLVGCAYSAAGSLVCGIIDYLRLIPGDKHLETWVK 576
            L+  + MDYSLL G   + +  LV GIIDY+R    DK LE  VK
Sbjct: 2521 LSSLNVMDYSLLSGID-NQSNQLVVGIIDYMRKFTWDKALEMKVK 2564          

BLAST of EY674160 vs. ExPASy Swiss-Prot
Match: FYV1_DROME (Putative 1-phosphatidylinositol-3-phosphate 5-kinase OS=Drosophila melanogaster GN=fab1 PE=1 SV=2)

HSP 1 Score: 57.3806 bits (137), Expect = 1.355e-12
Identity = 36/113 (31.86%), Postives = 60/113 (53.10%), Query Frame = 2

Query:   50 LQRVREDEFASFDKFALHYFKHMNESFDSGNQTCLAKVLGIYQGTIKQPKSGKEMRHDLMVMDNLTFERNITRQYDLKRALHARYNTTVDGSGD-VLLDQNFCNDMNSSPLYV 385
            L+ +   +   F+ FA  YF++++        T LAK+ G+++ ++K+  S  E    +MVM+NL +  NI  ++DLK +   R     +  G+ VLLD+N      S PLYV
Sbjct: 1592 LKEMNSRDMTIFEPFAPKYFEYIDRCQQQQQPTLLAKIFGVFRVSVKKKDSFVE--RSVMVMENLFYGCNIENKFDLKGSERNRLVDPSNQQGEIVLLDENLVQMSWSKPLYV 1702          

HSP 2 Score: 36.965 bits (84), Expect = 1.355e-12
Identity = 21/39 (53.85%), Postives = 25/39 (64.10%), Query Frame = 1

Query:  460 MDYSLLVGCAYSAAGSLVCGIIDYLRLIPGDKHLETWVK 576
            MDYSLLVG      G LV GIIDY+R    DK +E+ +K
Sbjct: 1727 MDYSLLVGLD-KKNGVLVLGIIDYIRTFTLDKRVESIIK 1764