EY701066

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: ERG24_ARATH (Delta(14)-sterol reductase OS=Arabidopsis thaliana GN=FK PE=1 SV=2)

HSP 1 Score: 244.973 bits (624), Expect = 1.841e-70
Identity = 121/195 (62.05%), Postives = 145/195 (74.36%), Query Frame = 1

Query:   76 MDLGFLLHAIIPSVDSAAILITFLTYLAIAGSILPGKVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYMNFISATVISDRGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHVTGNLMHDWWFGIQLNPQFMAIDLKFFFVRAGMMGWLLINLSVLAKSIQDGTLSRSMILYQLFGEAYMLDYFIYE 660
            MDLG LL    PS+ S  +L+ +  YLA+AG ILPGKV+ G +L DG++L Y CN                 +  +S  V++DRG ELLS TFIF VLVT ALYV G  S NK SSLKPHV+GNL+HDWWFGIQLNPQFM+IDLKFFFVRAGMMGWLLINLS+LAKS+QDG+LS+SMILYQ+F   Y+LDYF++E
Sbjct:    5 MDLGVLL----PSLQSVYVLVFYFVYLAVAGEILPGKVIRGVLLSDGSQLRYRCNGLLALILLVAILGICAKLGIVSPLVVADRGLELLSATFIFCVLVTLALYVTGRSSSNKGSSLKPHVSGNLVHDWWFGIQLNPQFMSIDLKFFFVRAGMMGWLLINLSILAKSVQDGSLSQSMILYQIFCALYILDYFVHE 195          

HSP 2 Score: 42.3578 bits (98), Expect = 1.841e-70
Identity = 19/32 (59.38%), Postives = 23/32 (71.88%), Query Frame = 3

Query:  669 VTSRWDIMAERSGFMWVFGDGVGVPVAVGIQG 764
            +TS WDI+AER GFM VFGD + +P    IQG
Sbjct:  198 MTSTWDIIAERLGFMLVFGDLLWIPFTFSIQG 229          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: ERG24_DICDI (Delta(14)-sterol reductase OS=Dictyostelium discoideum GN=erg24 PE=3 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 4.821e-17
Identity = 56/202 (27.72%), Postives = 95/202 (47.03%), Query Frame = 1

Query:   73 KMDLGFLLHAII----PSVDSAAILITFLTYLAIAGSILPGKVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYMNFISATVISDRGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHVTGNLMHDWWFGIQLNPQFMAIDLKFFF-VRAGMMGWLLINLSVLAKSIQ-DGTLSRSMILYQLFGEAYMLDYFIYE 660
            K  L  L H +I    P+ ++A I  ++  + A    ++PG+ V G+ L  G RL Y  N                Y     AT++ D    +++   I+S + T  L +       K    +  ++G+  +D+W G   NP+  + DLK F   R G++ W+L+N S+ AK ++  G +S S+IL   F   Y+ DY+ +E
Sbjct:   83 KAFLAQLYHYVITYAYPTKEAAIIYFSWFGFQAFLQHVVPGRKVLGSPLPGGARLEYTLNGWASWWITLIVIPIAIYFGLFKATILIDNYAPMMTVVNIWSFVFTFLLKIHA-----KLKGEEERMSGHFFYDFWMGFARNPRIGSFDLKLFCEARPGLILWVLMNFSIAAKQLEVYGEISLSVILVCCFHFWYIADYYYHE 279          

HSP 2 Score: 25.409 bits (54), Expect = 4.821e-17
Identity = 11/32 (34.38%), Postives = 18/32 (56.25%), Query Frame = 3

Query:  648 FYL*GSVVTSRWDIMAERSGFMWVFGDGVGVP 743
            +Y     + +  DI+ E+ G+M V+GD   VP
Sbjct:  275 YYYHEEAILTTMDIITEKFGYMLVYGDLSWVP 306          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: LBR_MOUSE (Lamin-B receptor OS=Mus musculus GN=Lbr PE=1 SV=2)

HSP 1 Score: 69.707 bits (169), Expect = 1.239e-13
Identity = 53/163 (32.52%), Postives = 80/163 (49.08%), Query Frame = 1

Query:  172 ILP-GKVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYMNFISATVISDRGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHVTGNLMHDWWFGIQLNPQFMAIDLKFFF-VRAGMMGWLLINLSVL---AKSIQDGTLSRSMILYQLFGEAYMLD 645
            +LP GKV  G  L DG RL Y  N                +   +    +     +L      FSVL+++ LYV   R+  +   L P  +GN ++D++ G +LNP+  A DLKFF  +R G++GW++INL +L    K  +    S +MIL   F   Y++D
Sbjct:  285 LLPVGKVAEGTPLVDGRRLQYRLNGLYAFILTSAALGAAVFWG-VELCYLYTHFLQLALAATGFSVLLSAYLYVRSLRAPREE--LSPASSGNAVYDFFIGRELNPRLGAFDLKFFCELRPGLIGWVVINLVMLLMEMKIQERAAPSLAMILVNSFQLLYVVD 444          

HSP 2 Score: 26.9498 bits (58), Expect = 1.239e-13
Identity = 13/26 (50.00%), Postives = 15/26 (57.69%), Query Frame = 3

Query:  684 DIMAERSGFMWVFGDGVGVPVAVGIQ 761
            DIM +  GFM  FGD V VP    +Q
Sbjct:  457 DIMHDGFGFMLAFGDLVWVPFTYSLQ 482          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: ERG24_ASCIM (Delta(14)-sterol reductase OS=Ascobolus immersus GN=ERG3 PE=3 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 9.364e-13
Identity = 58/195 (29.74%), Postives = 96/195 (49.23%), Query Frame = 1

Query:   88 FLLHAIIPSVDSAAILITFLTYLAIAGSILPGKVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYM---NFISATVISDRGFELLSTTFIFSVLVTSALYVAGCR--SRNKSSSLKP-HVTGNLMHDWWFGIQLNPQFMA-IDLK-FFFVRAGMMGWLLINLSVLAKSIQ-DGTLSRSMILYQLFGEAYMLD 645
            F LHA + +V +  +L+  L Y      +LP ++  G VL+DG+RL Y CN                 +    +   + ++D   +L S + +FS  ++  +Y+   R   + K   L P    GN +HD+W G +LNP+    +D+K    +R G+MGW+L NL+   K     G +S S++L  LF   Y++D
Sbjct:   61 FSLHATL-AVAAYYLLLVALMY------VLPAEIAEGVVLKDGSRLKYRCNAFTTFLVFFTFLGTMTVLEGPTWWFWSYLTDNFAQLQSASIVFSYAMSLWVYIRSYRPMPKGKEVILSPVGFKGNHIHDFWMGRELNPRIGEWLDIKQLHELRPGLMGWILFNLAWTVKQYNTHGFVSDSIVLVNLFETWYVVD 248          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: LBR_RAT (Lamin-B receptor OS=Rattus norvegicus GN=Lbr PE=1 SV=1)

HSP 1 Score: 67.781 bits (164), Expect = 1.302e-12
Identity = 53/175 (30.29%), Postives = 82/175 (46.86%), Query Frame = 1

Query:  151 YLAIAGSILP-GKVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYMNFISATVISDRGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHVTGNLMHDWWFGIQLNPQFMAIDLKFFF-VRAGMMGWLLINLSVL---AKSIQDGTLSRSMILYQLFGEAYMLDYFIYE 660
            +L    S+LP GKVV G  L DG RL Y  N                + + I    +     +      +FSV+++  LY    +       L P  +GN ++D++ G +LNP+  A DLKFF  +R G++GW++INL +L    K  +    S +M L   F   Y++D   +E
Sbjct:  272 FLQALFSLLPVGKVVEGTPLVDGRRLKYRLNGLYAFILTSAAVGTAVFWD-IELYYLYTHFLQFALAAIVFSVVLSVYLYARSLKVPR--DELSPASSGNAVYDFFIGRELNPRIGAFDLKFFCELRPGLIGWVVINLVMLLAEMKVQERSAPSLAMTLVNSFQLLYVVDALWFE 443          

HSP 2 Score: 25.409 bits (54), Expect = 1.302e-12
Identity = 12/26 (46.15%), Postives = 15/26 (57.69%), Query Frame = 3

Query:  684 DIMAERSGFMWVFGDGVGVPVAVGIQ 761
            DI+ +  GFM  FGD V VP    +Q
Sbjct:  451 DIIHDGFGFMLAFGDLVWVPFTYSLQ 476          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: LBR_PONAB (Lamin-B receptor OS=Pongo abelii GN=LBR PE=2 SV=1)

HSP 1 Score: 64.6994 bits (156), Expect = 2.301e-11
Identity = 54/164 (32.93%), Postives = 83/164 (50.61%), Query Frame = 1

Query:  172 ILP-GKVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYMNFISATVISD-RGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHVTGNLMHDWWFGIQLNPQFMAIDLKFFF-VRAGMMGWLLINLSVL--AKSIQDGTL-SRSMILYQLFGEAYMLD 645
            +LP GKVV G  L DG RL Y  N                +       V S    F L +T  +F V+++  LY+   ++    + L P  +GN ++D++ G +LNP+    DLK+F  +R G++GW++INL +L     IQD  + S +MIL   F   Y++D
Sbjct:  274 LLPIGKVVEGTPLIDGRRLKYRLNGFYAFILTSAVIGTSLFQGVEFHYVYSHFLQFALAAT--VFCVVLSVYLYMRSLKAPR--NDLSPASSGNAVYDFFIGRELNPRIGTFDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSLAMILVNSFQLLYVVD 433          

HSP 2 Score: 24.2534 bits (51), Expect = 2.301e-11
Identity = 12/26 (46.15%), Postives = 14/26 (53.85%), Query Frame = 3

Query:  684 DIMAERSGFMWVFGDGVGVPVAVGIQ 761
            DI+ +  GFM  FGD V VP     Q
Sbjct:  446 DIIHDGFGFMLAFGDLVWVPFIYSFQ 471          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: LBR_HUMAN (Lamin-B receptor OS=Homo sapiens GN=LBR PE=1 SV=2)

HSP 1 Score: 64.6994 bits (156), Expect = 2.301e-11
Identity = 54/164 (32.93%), Postives = 83/164 (50.61%), Query Frame = 1

Query:  172 ILP-GKVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYMNFISATVISD-RGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHVTGNLMHDWWFGIQLNPQFMAIDLKFFF-VRAGMMGWLLINLSVL--AKSIQDGTL-SRSMILYQLFGEAYMLD 645
            +LP GKVV G  L DG RL Y  N                +       V S    F L +T  +F V+++  LY+   ++    + L P  +GN ++D++ G +LNP+    DLK+F  +R G++GW++INL +L     IQD  + S +MIL   F   Y++D
Sbjct:  274 LLPIGKVVEGTPLIDGRRLKYRLNGFYAFILTSAVIGTSLFQGVEFHYVYSHFLQFALAAT--VFCVVLSVYLYMRSLKAPR--NDLSPASSGNAVYDFFIGRELNPRIGTFDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSLAMILVNSFQLLYVVD 433          

HSP 2 Score: 24.2534 bits (51), Expect = 2.301e-11
Identity = 12/26 (46.15%), Postives = 14/26 (53.85%), Query Frame = 3

Query:  684 DIMAERSGFMWVFGDGVGVPVAVGIQ 761
            DI+ +  GFM  FGD V VP     Q
Sbjct:  446 DIIHDGFGFMLAFGDLVWVPFIYSFQ 471          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: ERG24_SCHPO (Delta(14)-sterol reductase OS=Schizosaccharomyces pombe GN=erg24 PE=2 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 3.920e-11
Identity = 49/191 (25.65%), Postives = 87/191 (45.55%), Query Frame = 1

Query:  109 PSVDSAAILITFLTY--LAIAGSILPGKVVPGAVLQD-GTRLHYLCNXXXXXXXXXXXXXXXXYMNFISAT-VISDRGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHVTGNLMHDWWFGIQLNPQFMAIDLKFFF-VRAGMMGWLLINLSVLAKS--IQDGTLSRSMILYQLFGEAYMLDYFIYE 660
            P  D  ++++  L +  L +      GK   G  + D GTRL Y  N                Y+   S    I D   +L+   ++FSV++ +  YV     + + +  K   +GN++ DW+ G  LNP+    D+K F  +R G++ W++ +++       +  G ++ SM+L  +F   Y+LD  I E
Sbjct:   59 PLFDQKSLILYLLWFSTLTLLWKCTNGKWAKGTPIDDKGTRLLYKINGFNSACLILGVVCTSIYLLGASCMEFIWDNFLQLMFAAYVFSVVLCTFCYVQSFFGKQQLA--KGGTSGNILFDWFIGRSLNPRIGNFDIKCFCELRPGLILWVVFDIAFACHQYLVLGGRITDSMVLVIIFHTWYVLDSLINE 247          

HSP 2 Score: 27.335 bits (59), Expect = 3.920e-11
Identity = 21/58 (36.21%), Postives = 28/58 (48.28%), Query Frame = 3

Query:  663 SVVTSRWDIMAERSGFMWVFGDGVGVPVAVGIQGLVALA*AGGSSELGLWKPIA*RCV 836
            S V +  DI  +  G+M  FGD V VP    +Q   A   A    +LGL K +A  C+
Sbjct:  248 SAVLTTMDITTDGFGYMLSFGDLVWVPFLYSLQ---ARYLAFHPVDLGLVKTLAILCL 302          

BLAST of EY701066 vs. ExPASy Swiss-Prot
Match: ERG24_MOUSE (Delta(14)-sterol reductase OS=Mus musculus GN=Tm7sf2 PE=2 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 8.577e-11
Identity = 59/201 (29.35%), Postives = 97/201 (48.26%), Query Frame = 1

Query:   94 LHAIIPSVDSA----AILITFLTY-LAIAGSILPG-KVVPGAVLQDGTRLHYLCNXXXXXXXXXXXXXXXXYMNFISATV---ISDRGFELLSTTFIFSVLVTSALYVAGCRSRNKSSSLKPHV-TGNLMHDWWFGIQLNPQFMAIDLKFFF-VRAGMMGWLLINLSVLAKSIQ-DGTLSRSMILYQLFGEAYMLDYFIYE 660
            L A +P ++      A+L+ F+   L +A  +LP  KV  G  L+D +RL Y  N                 +      +   +    F    T+FIFS+L+ +   VA       +S+L P   +GN M+D++ G +LNP+  + D K+F  +R G++GW+ INL++L +  +  G+ S +M L   F   Y+ D   YE
Sbjct:   47 LPAYLPGLEELWSPWALLLLFIWLGLQVALYLLPARKVAEGLELKDKSRLRYPINGFQALVLTALLMGLGVSVGLPLGALPGMLLPLAFATTLTSFIFSLLLYAKALVA------PASALAPGGNSGNSMYDFFLGRELNPRLGSFDFKYFCELRPGLIGWVFINLALLMQEAELRGSPSLAMWLVNGFQLLYVGDALWYE 241          

HSP 2 Score: 26.1794 bits (56), Expect = 8.577e-11
Identity = 13/31 (41.94%), Postives = 17/31 (54.84%), Query Frame = 3

Query:  669 VTSRWDIMAERSGFMWVFGDGVGVPVAVGIQ 761
            V +  DI+ +  GFM VFGD   VP    +Q
Sbjct:  244 VLTTMDIIHDGFGFMLVFGDLAWVPFTYSLQ 274