CX043274

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR_ORYSJ (Probable methylenetetrahydrofolate reductase OS=Oryza sativa subsp. japonica GN=Os03g0815200 PE=2 SV=1)

HSP 1 Score: 510.76 bits (1314), Expect = 3.818e-144
Identity = 242/275 (88.00%), Postives = 255/275 (92.73%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQFMRPRSRDKKLHEEWAVP 827
            DPPHGQDKFVQ+ GGFACALDLV+HIR+ YGDYFGITVAGYPE HPD I     A+ E+Y +DL YLK+KVDAGADLIITQLFYDTD+FLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLG EMCKKILA GIKTLHLYTLNMEKSAL IL+NLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSY+SRT+GWDQYP GRWGDSRNPSYGAL+D+QF RPR R KKL EEWAVP
Sbjct:  113 DPPHGQDKFVQVAGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQSTEGATPEAYSNDLAYLKQKVDAGADLIITQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGTEMCKKILATGIKTLHLYTLNMEKSALGILMNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYISRTLGWDQYPHGRWGDSRNPSYGALTDYQFTRPRGRGKKLQEEWAVP 387          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR2_ARATH (Methylenetetrahydrofolate reductase 2 OS=Arabidopsis thaliana GN=MTHFR2 PE=1 SV=2)

HSP 1 Score: 505.753 bits (1301), Expect = 1.228e-142
Identity = 232/275 (84.36%), Postives = 256/275 (93.09%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQFMRPRSRDKKLHEEWAVP 827
            DPPHGQDKFVQ++GGF CALDLV HIRS YGDYFGITVAGYPE HPD IG +G+ASNE+YQSDL YLKKK+DAGADLI+TQLFYDTD+FLKFVNDCRQIGI+CPIVPGIMPINNY+GFLRMTGFCKTKIP E+ AALEPIKDNEEAVKAYGIHLG EMCKK+LAHG+K+LHLYTLNMEKSALAIL+NLG+I+ESKISRSLPWR P NVFR KEDVRPIFWANRPKSY+SRT GW+ +P+GRWGDSR+ SYGALSDHQF RPR+RDKKL +EW VP
Sbjct:  113 DPPHGQDKFVQVEGGFDCALDLVNHIRSKYGDYFGITVAGYPEAHPDVIGENGLASNEAYQSDLEYLKKKIDAGADLIVTQLFYDTDIFLKFVNDCRQIGISCPIVPGIMPINNYRGFLRMTGFCKTKIPVEVMAALEPIKDNEEAVKAYGIHLGTEMCKKMLAHGVKSLHLYTLNMEKSALAILMNLGMIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWEDFPQGRWGDSRSASYGALSDHQFSRPRARDKKLQQEWVVP 387          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR1_MAIZE (Methylenetetrahydrofolate reductase 1 OS=Zea mays PE=2 SV=1)

HSP 1 Score: 504.212 bits (1297), Expect = 3.574e-142
Identity = 234/275 (85.09%), Postives = 254/275 (92.36%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQFMRPRSRDKKLHEEWAVP 827
            DPPHGQDKFVQ++GGFACALDLV+HIR+ YGDYFGITVAGYPE HPD I  +G A+ E+Y +DL YLK+KVDAGADLI+TQLFYDTD+FLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIP+EITAAL+PIKDNEEAV+ YGIHLG EMCKKILA GIKTLHLYTLNM+KSA+ IL+NLGLIEESK+SR LPWRP TNVFRVKEDVRPIFWANRPKSYL RT+GWDQYP GRWGDSRNPSYGAL+DHQF RPR R KKL EEWAVP
Sbjct:  113 DPPHGQDKFVQVEGGFACALDLVQHIRAKYGDYFGITVAGYPEAHPDAIQGEGGATLEAYSNDLAYLKRKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPSEITAALDPIKDNEEAVRQYGIHLGTEMCKKILATGIKTLHLYTLNMDKSAIGILMNLGLIEESKVSRPLPWRPATNVFRVKEDVRPIFWANRPKSYLKRTLGWDQYPHGRWGDSRNPSYGALTDHQFTRPRGRGKKLQEEWAVP 387          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR1_ARATH (Methylenetetrahydrofolate reductase 1 OS=Arabidopsis thaliana GN=MTHFR1 PE=1 SV=1)

HSP 1 Score: 483.797 bits (1244), Expect = 4.999e-136
Identity = 223/275 (81.09%), Postives = 246/275 (89.45%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHGIKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQFMRPRSRDKKLHEEWAVP 827
            DPPHGQDKFVQ++GGFACALDLV HIRS YGDYFGITVAGYPE HPD I  DG+A+ ESYQSDL YLKKKVDAGADLI+TQLFYDTD+FLKFVNDCRQIGI CPIVPGIMPI+NYKGFLRM GFCKTKIPAE+TAALEPIKDN+EAVKAYGIH   EMCKKILAHGI +LHLYTLN++KSA+ IL+NLGLI+ESKISRSLPWR P NVFR KEDVRPIFWANRPKSY+SRT GW+ +P GRWGDS + +Y  LSD+QF RP+ RDKKL +EW VP
Sbjct:  113 DPPHGQDKFVQVEGGFACALDLVNHIRSKYGDYFGITVAGYPEAHPDVIEADGLATPESYQSDLAYLKKKVDAGADLIVTQLFYDTDIFLKFVNDCRQIGINCPIVPGIMPISNYKGFLRMAGFCKTKIPAELTAALEPIKDNDEAVKAYGIHFATEMCKKILAHGITSLHLYTLNVDKSAIGILMNLGLIDESKISRSLPWRRPANVFRTKEDVRPIFWANRPKSYISRTKGWNDFPHGRWGDSHSAAYSTLSDYQFARPKGRDKKLQQEWVVP 387          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR_HUMAN (Methylenetetrahydrofolate reductase OS=Homo sapiens GN=MTHFR PE=1 SV=3)

HSP 1 Score: 259.996 bits (663), Expect = 1.174e-68
Identity = 127/269 (47.21%), Postives = 178/269 (66.17%), Query Frame = 3

Query:   21 DKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHG-IKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQ--FMRPRSRDKKLHEEW 818
            D++ + +GGF  A+DLVKHIRS +GDYF I VAGYP+GHP+           S+++DL +LK+KV AGAD IITQLF++ D F +FV  C  +GITCPIVPGI PI  Y    ++    K ++P EI   +EPIKDN+ A++ YGI L   +C+++LA G +  LH YTLN E +   +L  LG+  E    R LPW    +  R +EDVRPIFWA+RPKSY+ RT  WD++P GRWG+S +P++G L D+   +++ +S  ++L + W
Sbjct:  163 DQWEEEEGGFNYAVDLVKHIRSEFGDYFDICVAGYPKGHPEA---------GSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKLSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCQELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW 421          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR_MACFA (Methylenetetrahydrofolate reductase OS=Macaca fascicularis GN=MTHFR PE=2 SV=1)

HSP 1 Score: 255.758 bits (652), Expect = 2.214e-67
Identity = 126/269 (46.84%), Postives = 176/269 (65.43%), Query Frame = 3

Query:   21 DKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHG-IKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQ--FMRPRSRDKKLHEEW 818
            D++ + +GGF  A+DLVKHIRS +GDYF + VAGYP+GHP+           S+++DL +LK+KV AGAD IITQLF++ D F +FV  C  +GITCPIVPGI PI  Y    ++    K ++P EI   +EPIKDN+ A++ YGI L   +C ++LA G +  LH YTLN E +   +L  LG+  E    R LPW    +  R +EDVRPIFWA+RPKSY+ RT  WD++P GRWG+S +P++G L D+   +++ +S  + L + W
Sbjct:  163 DQWEEEEGGFNYAVDLVKHIRSEFGDYFDLCVAGYPKGHPEA---------GSFEADLKHLKEKVSAGADFIITQLFFEADTFFRFVKACTDMGITCPIVPGIFPIQGYHSLRQLVKQSKLEVPQEIKDVIEPIKDNDAAIRNYGIELAVSLCHELLASGLVPGLHFYTLNREMATTEVLKRLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPRELLLKMW 421          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR_BOVIN (Methylenetetrahydrofolate reductase OS=Bos taurus GN=MTHFR PE=2 SV=1)

HSP 1 Score: 255.373 bits (651), Expect = 2.892e-67
Identity = 124/270 (45.93%), Postives = 181/270 (67.04%), Query Frame = 3

Query:   21 DKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHG-IKTLHLYTLNMEKSALAILLNLGL-IEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQ--FMRPRSRDKKLHEEW 818
            D++ + +GGF  A DLVKHIR+ +GDYF + VAGYP+GHP+          ES+++DL +LK+KV AGAD IITQLF++ + F +FV  C +IGITCP++PGI PI  Y    ++    K ++P +I   +EPIKDN+ A++ YGI     +C+++LA G +  LH YTLN E + + +L  LGL IE+ +  R LPW    +  R  EDVRPIFWA+RPKSY+ RT  WD++P GRWG+S +P++G L D+   +++ +S  ++L + W
Sbjct:  162 DQWEEEEGGFNYATDLVKHIRNEFGDYFDVCVAGYPKGHPE---------GESFEADLKHLKEKVAAGADFIITQLFFEAETFFRFVKACSEIGITCPVLPGIFPIQGYHSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQAVSLCQELLASGLVPGLHFYTLNREVATIEVLKRLGLWIEDPR--RPLPWALSAHPKRRVEDVRPIFWASRPKSYIYRTQEWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMW 420          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR_MOUSE (Methylenetetrahydrofolate reductase OS=Mus musculus GN=Mthfr PE=2 SV=1)

HSP 1 Score: 251.906 bits (642), Expect = 3.197e-66
Identity = 122/263 (46.39%), Postives = 171/263 (65.02%), Query Frame = 3

Query:   39 QGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHG-IKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDHQ--FMRPRSRDKKLHEEW 818
            +GGF+ A DLVKHIR+ + DYF I VAGYP GHPD          ES++ DL +LK+KV AGAD IITQLF++   F  FV  C +IGI+CPI+PGI PI  Y    ++    K ++P +I   +EPIKDN+ A++ YGI L   +C+++L  G +  LH YTLN E + + +L  LG+  E    R LPW    +  R +EDVRPIFWA+RPKSY+ RT  WD++P GRWG+S +P++G L D+   +++ +S  ++L + W
Sbjct:  168 EGGFSYATDLVKHIRTEFADYFDICVAGYPRGHPDA---------ESFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQGYTSLRQLVKLSKLEVPQKIKDVIEPIKDNDAAIRNYGIELAVRLCRELLDSGLVPGLHFYTLNREVATMEVLKQLGMWTEDP-RRPLPWALSAHPKRREEDVRPIFWASRPKSYIYRTQDWDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPREELLKMW 420          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR2_YEAST (Methylenetetrahydrofolate reductase 2 OS=Saccharomyces cerevisiae GN=MET13 PE=1 SV=2)

HSP 1 Score: 234.572 bits (597), Expect = 5.282e-61
Identity = 124/283 (43.82%), Postives = 173/283 (61.13%), Query Frame = 3

Query:    3 DPPHGQDKFVQIQGGFACALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHG-IKTLHLYTLNMEKSALAILLNLGLI-EESKISRS----LPWRPPTNVFRVKEDVRPIFWANRPKSYLSRTVGW--DQYPRGRWGDSRNPSYGALSDHQFMRPRSRDKKLHEEWAVP 827
            DPP   + +  ++GGF  A DL+K+I+S YGD+F I VAGYPE HP+         N+  + DL YLK+K+DAG D IITQ+FYD D F+ + +  R  G+  PI+PGIMPI  Y  FLR   + +  IP   ++ L+PIKD++E V+  G +L  EMC+K+L  G +  LH+YT+N+EK+ L IL  L ++  ES+ +      LPWR   N  R  E+VRPIFW  RP SY++RT  W  D++P GR+GDS +P++G L        R    K  E W+ P
Sbjct:  116 DPPRDAENWTPVEGGFQYAKDLIKYIKSKYGDHFAIGVAGYPECHPEL-------PNKDVKLDLEYLKQKIDAGGDFIITQMFYDVDNFINWCSQVRAAGMDVPIIPGIMPITTYAAFLRRAQWGQISIPQHFSSRLDPIKDDDELVRDIGTNLIVEMCQKLLDSGYVSHLHIYTMNLEKAPLMILERLNILPTESEFNAHPLAVLPWRKSLNPKRKNEEVRPIFWKRRPYSYVARTSQWAVDEFPNGRFGDSSSPAFGDLDLCGSDLIRQSANKCLELWSTP 391          

BLAST of CX043274 vs. ExPASy Swiss-Prot
Match: MTHR_CAEEL (Probable methylenetetrahydrofolate reductase OS=Caenorhabditis elegans GN=C06A8.1 PE=1 SV=2)

HSP 1 Score: 221.476 bits (563), Expect = 4.627e-57
Identity = 112/240 (46.67%), Postives = 159/240 (66.25%), Query Frame = 3

Query:   57 ALDLVKHIRSAYGDYFGITVAGYPEGHPDTIGPDGVASNESYQSDLLYLKKKVDAGADLIITQLFYDTDMFLKFVNDCRQIGITCPIVPGIMPINNYKGFLRMTGFCKTKIPAEITAALEPIKDNEEAVKAYGIHLGAEMCKKILAHG-IKTLHLYTLNMEKSALAILLNLGLIEESKISRSLPWRPPT-NVFRVKEDVRPIFWANRPKSYLSRTVGWDQYPRGRWGDSRNPSYGALSDH 770
            ALD+++ IR  YG+YF I  AGYP GHP            SY++DL+YLK K DAGA+ +ITQLF++ + F KFV DCR+IGIT PI+PGIMPI  Y+   R+    + +IP  I   LEPIK +++AV+ YG     EMC+++L +G   ++HLYT+N E S   IL +LGL  + +  R  PW+  + +  R  E VRPI+W+ RP+SY++RT  WDQ+P GRWG+S +P++G +S +
Sbjct:  188 ALDMIRWIREEYGNYFSIGCAGYPLGHPQA---------PSYKADLMYLKAKCDAGANFVITQLFFEAETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIAKLSQLEIPQHILDDLEPIKHDDDAVQKYGTERCIEMCRRLLDNGTAPSIHLYTMNREGSIREILKSLGL-WKLEGDRVFPWKNRSQHPIRCLESVRPIYWSFRPRSYITRTRDWDQFPNGRWGNSSSPAFGDVSSY 417