CX286963

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_ARATH (DNA topoisomerase 1 OS=Arabidopsis thaliana GN=TOP1 PE=1 SV=1)

HSP 1 Score: 201.06 bits (510), Expect = 1.644e-51
Identity = 90/117 (76.92%), Postives = 101/117 (86.32%), Query Frame = 3

Query:   15 KKTKKVIKNSQYSKSTKMLPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWH 365
            K TKKV K+S+YS S+K  P SGDGQKKWTTLVHNGVIFPPPY PHG+K+LYKGK V+LT EQEEVATMFAVM +TDY  KP+FRENFWNDWR+LLGK HVIQ L+ CDF PIY+WH
Sbjct:  343 KNTKKVTKDSKYSTSSKSSPSSGDGQKKWTTLVHNGVIFPPPYKPHGIKILYKGKPVDLTIEQEEVATMFAVMRETDYYTKPQFRENFWNDWRRLLGKKHVIQKLDDCDFTPIYEWH 459          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_DAUCA (DNA topoisomerase 1 OS=Daucus carota GN=TOP1 PE=2 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 3.931e-37
Identity = 75/123 (60.98%), Postives = 89/123 (72.36%), Query Frame = 3

Query:    6 RHRKKTKKVIKNSQYSKSTKM---LPGSGDGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGKNHVIQNLEGCDFKPIYDWH 365
            + R      +    +SKS K+   L    +GQ     LVHNGVIFPP Y PHGVKMLY+   V+LTPEQEEVATMFAVML+T+YM KPKFRENF +DWRK+LG+ H+IQNLE CDF PIY+WH
Sbjct:  187 KKRPDVSASVNKVDFSKSLKVPLVLVKGRNGQP----LVHNGVIFPPLYKPHGVKMLYRENPVDLTPEQEEVATMFAVMLETEYMTKPKFRENFMSDWRKILGEKHIIQNLEDCDFTPIYEWH 305          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_DICDI (DNA topoisomerase 1 OS=Dictyostelium discoideum GN=top1 PE=3 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 2.094e-22
Identity = 44/93 (47.31%), Postives = 68/93 (73.12%), Query Frame = 3

Query:   84 DGQKKWTTLVHNGVIFPPPYLPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLL--GKNHVIQNLEGCDFKPIY 356
            D   KWTTL+HNG +FPP Y+PHG+K +Y GK V LTP+QEEVAT +A  L+TD+++K  F++NF+ +++ LL   +  +++ ++ CDF  I+
Sbjct:  307 DDGTKWTTLIHNGPVFPPAYVPHGIKFMYDGKVVKLTPKQEEVATFYANYLETDHVKKQAFKDNFFKEFKGLLTSEQKEIVKKMDKCDFSHIH 399          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_SCHPO (DNA topoisomerase 1 OS=Schizosaccharomyces pombe GN=top1 PE=1 SV=2)

HSP 1 Score: 96.6709 bits (239), Expect = 4.367e-20
Identity = 47/96 (48.96%), Postives = 63/96 (65.62%), Query Frame = 3

Query:   84 DGQKKWTTLVHNGVIFPPPY--LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGK---NHVIQNLEGCDFKPIY 356
            D  +KWTTL HNGVIF PPY  LP  VK++Y G  VNL PE EEVA  +A ML+TD+ + P F++NF+ D+ K+  +   NH I+    CDF  ++
Sbjct:  190 DDTQKWTTLEHNGVIFAPPYEPLPKNVKLIYDGNPVNLPPEAEEVAGFYAAMLETDHAKNPVFQDNFFRDFLKVCDECNFNHNIKEFSKCDFTQMF 285          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_CANAL (DNA topoisomerase 1 OS=Candida albicans GN=TOP1 PE=3 SV=1)

HSP 1 Score: 93.2041 bits (230), Expect = 4.828e-19
Identity = 48/98 (48.98%), Postives = 62/98 (63.27%), Query Frame = 3

Query:   81 GDGQKKWTTLVHNGVIFPPPY--LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLL----GKNHVIQNLEGCDFKPIY 356
            GDG  KW TL HNGV+FPPPY  LP  VK+ Y  K VNL PE EEVA  +  ML+TD+ + P F++NF+ND+ ++L    G    I+  E  DF  +Y
Sbjct:  151 GDGYIKWQTLEHNGVMFPPPYEPLPSHVKLYYNNKPVNLPPEAEEVAGFYGAMLETDHAKNPVFQKNFFNDFLEVLKECGGCGVEIKKFEKLDFSKMY 248          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_CRIGR (DNA topoisomerase 1 OS=Cricetulus griseus GN=TOP1 PE=2 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 1.835e-18
Identity = 56/129 (43.41%), Postives = 71/129 (55.04%), Query Frame = 3

Query:   15 KKTKKVIKNSQYSKST--KMLPGSGDGQK-------------KWTTLVHNGVIFPPPY--LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLL--GKNHVIQNLEGCDF 344
            KKTK   K+ + ++S   K  P   + QK             KW  L H G +F PPY  LP GVK  Y GK + L+P+ EEVAT FA MLD +Y  K  FR+NF+ DWRK +   + +VI NL  CDF
Sbjct:  176 KKTKNKDKDKKGAESDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNVITNLSKCDF 304          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_YEAST (DNA topoisomerase 1 OS=Saccharomyces cerevisiae GN=TOP1 PE=1 SV=2)

HSP 1 Score: 89.7373 bits (221), Expect = 5.338e-18
Identity = 44/101 (43.56%), Postives = 65/101 (64.36%), Query Frame = 3

Query:   84 DGQKKWTTLVHNGVIFPPPY--LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLLGKNH------VIQNLEGCDFKPIYDW 362
            D   KW TL HNGVIFPPPY  LP  +K+ Y GK V+L P+ EEVA  FA +L++D+ + P F++NF+ND+ ++L ++        I+    CDF  ++D+
Sbjct:  140 DDTIKWVTLKHNGVIFPPPYQPLPSHIKLYYDGKPVDLPPQAEEVAGFFAALLESDHAKNPVFQKNFFNDFLQVLKESGGPLNGIEIKEFSRCDFTKMFDY 240          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_RAT (DNA topoisomerase 1 OS=Rattus norvegicus GN=Top1 PE=2 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 9.105e-18
Identity = 45/87 (51.72%), Postives = 55/87 (63.22%), Query Frame = 3

Query:   96 KWTTLVHNGVIFPPPY--LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLL--GKNHVIQNLEGCDF 344
            KW  L H G +F PPY  LP GVK  Y GK + L+P+ EEVAT FA MLD +Y  K  FR+NF+ DWRK +   + + I NL  CDF
Sbjct:  218 KWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNTITNLSKCDF 304          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_HUMAN (DNA topoisomerase 1 OS=Homo sapiens GN=TOP1 PE=1 SV=2)

HSP 1 Score: 87.4261 bits (215), Expect = 2.649e-17
Identity = 44/87 (50.57%), Postives = 55/87 (63.22%), Query Frame = 3

Query:   96 KWTTLVHNGVIFPPPY--LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLL--GKNHVIQNLEGCDF 344
            KW  L H G +F PPY  LP  VK  Y GK + L+P+ EEVAT FA MLD +Y  K  FR+NF+ DWRK +   + ++I NL  CDF
Sbjct:  216 KWKFLEHKGPVFAPPYEPLPENVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDF 302          

BLAST of CX286963 vs. ExPASy Swiss-Prot
Match: TOP1_CERAE (DNA topoisomerase 1 OS=Cercopithecus aethiops GN=TOP1 PE=2 SV=1)

HSP 1 Score: 87.0409 bits (214), Expect = 3.460e-17
Identity = 44/87 (50.57%), Postives = 55/87 (63.22%), Query Frame = 3

Query:   96 KWTTLVHNGVIFPPPY--LPHGVKMLYKGKEVNLTPEQEEVATMFAVMLDTDYMQKPKFRENFWNDWRKLL--GKNHVIQNLEGCDF 344
            KW  L H G +F PPY  LP  VK  Y GK + L+P+ EEVAT FA MLD +Y  K  FR+NF+ DWRK +   + ++I NL  CDF
Sbjct:  218 KWKFLEHKGPVFAPPYEPLPDSVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNEEKNIITNLSKCDF 304