FC930019

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: ALDR_RABIT (Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3)

HSP 1 Score: 90.8929 bits (224), Expect = 3.414e-30
Identity = 58/140 (41.43%), Postives = 81/140 (57.86%), Query Frame = 3

Query:    9 EKALGEAIAEALRLGLVTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEE---EEVGMSLPNKEDLSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATI--PPSINQV 413
            E  +G A+ E L+  +V  RE+LFI SKLWC +     V  A +K+L+ L+++YLDLYLIHWP   K  SE    +  G  +P     S  D+   WEAME     GL KSIG+SNF+  +I+ IL    +   P++NQ+
Sbjct:   52 ENEVGVALQEKLKEQVV-KREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDAAGNVIP-----SDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQI 185          

HSP 2 Score: 62.003 bits (149), Expect = 3.414e-30
Identity = 30/78 (38.46%), Postives = 49/78 (62.82%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTRWGSNQ---VMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            ++E HP   Q KL ++C  KG+ VTAYSPLG+    W   +   ++E+  +K IA+ H KT AQV +R+ +++ + V+
Sbjct:  184 QIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVVI 261          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: S6PD_MALDO (NADP-dependent D-sorbitol-6-phosphate dehydrogenase OS=Malus domestica GN=S6PDH PE=2 SV=1)

HSP 1 Score: 97.8265 bits (242), Expect = 4.447e-30
Identity = 56/139 (40.29%), Postives = 86/139 (61.87%), Query Frame = 3

Query:    6 TEKALGEAIAEALRLGLVTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEEEEVGMSLPNKEDLSPLD----YKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATIPPSINQ 410
            +E  +GEA+AEA + GLV  RE+LFIT+K+W  N+ H  V+ A K SL  LQ++YLDLYL+H+P+  K  +  +    SL  ++ +  +D     +  WE ME++  LGL +SIGLSN+        L ++ I P+++Q
Sbjct:   50 SEADVGEALAEAFKTGLV-KREELFITTKIW--NSDHGHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKTA--SLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAVSQ 183          

HSP 2 Score: 54.6842 bits (130), Expect = 4.447e-30
Identity = 26/76 (34.21%), Postives = 45/76 (59.21%), Query Frame = 1

Query:  502 EMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTR---WGSNQVMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            E HP +Q+  L +FC   G+  TA++PLG        +GS   +++  L  +A+ +GK+VAQ+ LRW +++   V+
Sbjct:  185 ETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAAANKDMFGSVSPLDDPVLNDVAKKYGKSVAQICLRWGIQRKTAVI 260          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 5.789e-30
Identity = 52/124 (41.94%), Postives = 74/124 (59.68%), Query Frame = 3

Query:   57 VTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSE---EEEVGMSLPNKEDLSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATI--PPSINQV 413
            V  RE LFI SKLWC     D V  A +K+LS L+++YLDLYLIHWP   KP  +    +E G  +P+++     D+   W AMEE    GL K+IG+SNF+  +++ IL    +   P++NQ+
Sbjct:   66 VVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKDFFPLDEDGNVIPSEK-----DFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQI 184          

HSP 2 Score: 62.003 bits (149), Expect = 5.789e-30
Identity = 29/78 (37.18%), Postives = 49/78 (62.82%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTRWGSNQ---VMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            ++E HP   Q KL ++C  KG+ VTAYSPLG+    W   +   ++E+  +K IA+ + KT AQV +R+ +++ + V+
Sbjct:  183 QIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIVI 260          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: ALDR_PIG (Aldose reductase OS=Sus scrofa GN=AKR1B1 PE=1 SV=2)

HSP 1 Score: 88.9669 bits (219), Expect = 5.789e-30
Identity = 54/142 (38.03%), Postives = 81/142 (57.04%), Query Frame = 3

Query:    9 EKALGEAIAEALRLGLVTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEE---EEVGMSLPNKEDLSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATI--PPSINQVSL 419
            E  +G  + E L+ G V  RE LFI SKLWC +   + V  A + +L  L+++YLDLYLIHWP   KP  +    +  G  +P++      D+   WEAMEE    GL K+IG+SNF+  +++ IL    +   P++NQ+ +
Sbjct:   52 ENEVGLGLQEKLQ-GQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKDPFPLDGDGNVVPDES-----DFVETWEAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIEV 187          

HSP 2 Score: 63.1586 bits (152), Expect = 5.789e-30
Identity = 31/78 (39.74%), Postives = 50/78 (64.10%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTRWGSNQ---VMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            ++E+HP   Q KL E+CK KG+ VTAYSPLG+    W   +   ++E+  +K IA  + KT AQV +R+ +++ + V+
Sbjct:  184 QIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVI 261          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: AK1A1_CRIGR (Alcohol dehydrogenase [NADP+] (Fragment) OS=Cricetulus griseus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 5.826e-30
Identity = 57/141 (40.43%), Postives = 83/141 (58.87%), Query Frame = 3

Query:    3 GTEKALGEAIAEALRLGLVTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEEEEVGMSLPNKED----LSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATIPPSINQV 413
            G E  +GEA+ E +  G    RE+LF+TSKLW    H + V  A++K+L+ LQ+EYLDLYL+HWP +       E      P  +D         YK  W+A+E     GL K++GLSNF+ ++ID IL+ A++ P++ QV
Sbjct:   36 GNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAF------ERGDNPFPKNDDGTIRYDSTHYKETWKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQV 170          

HSP 2 Score: 47.7506 bits (112), Expect = 5.826e-30
Identity = 24/67 (35.82%), Postives = 37/67 (55.22%), Query Frame = 1

Query:  475 ATRISFLKVEMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTRW---GSNQVMENEALKQIAEAHGK 666
            + R + L+VE HP   Q +L   C+ +G+ VTAYSPLG+    W       ++E   +  +AE HG+
Sbjct:  162 SVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGR 228          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 7.535e-30
Identity = 55/147 (37.41%), Postives = 89/147 (60.54%), Query Frame = 3

Query:    3 GTEKALGEAIAEALRLGLVTSREQLFITSKLW--CHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEEEEVGMSLPNKED------LSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATIPPSINQVSL 419
            G EK +G ++ E  + G +  RE +F TSKLW  CHN++   V+    K++  L + YLDLYLIHWPI+ + ++    +G+++    D      ++P+  +  W+ ME+   LGL KSIG+SNF+ + +  +LT+A I P +NQV +
Sbjct:   63 GNEKVIGNSLKEIFKEGEI-KREDIFYTSKLWNSCHNSN--LVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNP---LGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEI 203          

HSP 2 Score: 53.1434 bits (126), Expect = 7.535e-30
Identity = 27/75 (36.00%), Postives = 42/75 (56.00%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTRWGSNQVMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            +VE+HP   Q KL+E+C    + + AYSPLG      G      N+ LK IA  + K+VA V  +W+ ++G+  +
Sbjct:  200 QVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQ-----GKCDFFSNKILKSIAGKYKKSVANVIFKWLNQRGIAAI 269          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: ALDR_MOUSE (Aldose reductase OS=Mus musculus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 90.5077 bits (223), Expect = 7.537e-30
Identity = 57/140 (40.71%), Postives = 80/140 (57.14%), Query Frame = 3

Query:    9 EKALGEAIAEALRLGLVTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEE---EEVGMSLPNKEDLSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATI--PPSINQV 413
            EK +G A+ E L+  +V  R+ LFI SKLWC       V  A +K+LS LQ++YLDLYLIHWP   KP  +    +  G  +P     S  D+   W AME+    GL K+IG+SNF+  +I+ IL    +   P++NQ+
Sbjct:   52 EKEVGVALQEKLKEQVV-KRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIP-----SDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQI 185          

HSP 2 Score: 61.2326 bits (147), Expect = 7.537e-30
Identity = 30/78 (38.46%), Postives = 48/78 (61.54%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTRWGSNQ---VMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            ++E HP   Q KL E+C  KG+ VTAYSPLG+    W   +   ++E+  +K IA  + KT AQV +R+ +++ + V+
Sbjct:  184 QIECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVI 261          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: GR_BACSU (Glyoxal reductase OS=Bacillus subtilis GN=yvgN PE=1 SV=1)

HSP 1 Score: 83.1889 bits (204), Expect = 1.668e-29
Identity = 44/117 (37.61%), Postives = 64/117 (54.70%), Query Frame = 3

Query:   63 SREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEEEEVGMSLPNKEDLSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATIPPSINQV 413
            +RE+LFITSK+W  +  ++  + A +KSL  LQ++YLDLYLIHWP   K                      YK  W A+E+  + G  ++IG+SNF    ++ +L  A I P +NQV
Sbjct:   70 AREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDK----------------------YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQV 164          

HSP 2 Score: 67.3958 bits (163), Expect = 1.668e-29
Identity = 33/75 (44.00%), Postives = 49/75 (65.33%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGAVGTRWGSNQVMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            +VE HP   Q++LR++CK +G+ + A+SPL          Q+++NE L QIAE H K+VAQV LRW ++ GV  +
Sbjct:  163 QVEFHPRLTQKELRDYCKGQGIQLEAWSPLM-------QGQLLDNEVLTQIAEKHNKSVAQVILRWDLQHGVVTI 230          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: AK1C1_PONAB (Aldo-keto reductase family 1 member C1 homolog OS=Pongo abelii GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 2.165e-29
Identity = 56/137 (40.88%), Postives = 83/137 (60.58%), Query Frame = 3

Query:    9 EKALGEAIAEALRLGLVTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSEEEEVGMSLPNKEDLSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATI--PPSINQV 413
            E+ +G AI   +  G V  RE +F TSKLWC++   + V PA+++SL  LQ++Y+DLYL+H+P+S KP   EE +      K     +D    WEAME+ +  GL KSIG+SNF+ ++++ IL    +   P  NQV
Sbjct:   58 EEQVGLAIRSKIADGSV-KREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVKP--GEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQV 191          

HSP 2 Score: 53.5286 bits (127), Expect = 2.165e-29
Identity = 30/79 (37.97%), Postives = 50/79 (63.29%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGA-VGTRW---GSNQVMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            +VE HP + QRKL +FCK K + + AYS LG+    +W    S  ++E+  L  +A+ H +T A ++LR+ +++GV V+
Sbjct:  190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEKWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVL 268          

BLAST of FC930019 vs. ExPASy Swiss-Prot
Match: PGFS2_BOVIN (Prostaglandin F synthase 2 OS=Bos taurus PE=2 SV=1)

HSP 1 Score: 98.2117 bits (243), Expect = 2.819e-29
Identity = 58/140 (41.43%), Postives = 88/140 (62.86%), Query Frame = 3

Query:    9 EKALGEAIAEALRLGLVTSREQLFITSKLWCHNAHHDRVIPAIKKSLSALQMEYLDLYLIHWPISAKPTSE---EEEVGMSLPNKEDLSPLDYKGVWEAMEESQRLGLTKSIGLSNFSCKKIDTILTFATI--PPSINQV 413
            E+ +G+AI   +  G V  RE +F TSKLWC++   + V PA++KSL  LQ++Y+DLY+IH P+S KP ++   ++E G  + +  DL        WEA+E+ +  GLTKSIG+SNF+ K+++ IL    +   P  NQV
Sbjct:   58 EEQVGQAIRSKIADGTV-KREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLKPGNKFVPKDESGKLIFDSVDLC-----HTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKYKPVCNQV 191          

HSP 2 Score: 51.6026 bits (122), Expect = 2.819e-29
Identity = 31/79 (39.24%), Postives = 49/79 (62.03%), Query Frame = 1

Query:  496 KVEMHPVWQQRKLREFCKVKGMNVTAYSPLGA-VGTRWGSNQ---VMENEALKQIAEAHGKTVAQVSLRWIVEQGVTVV 720
            +VE HP   Q KL EFCK   + + AY+ LGA + + W ++    ++E+  L  IA+ H +T A V+LR+ V++GV V+
Sbjct:  190 QVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVL 268