FC931696

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: SMUF2_DANRE (E3 ubiquitin-protein ligase SMURF2 OS=Danio rerio GN=smurf2 PE=2 SV=1)

HSP 1 Score: 275.404 bits (703), Expect = 2.093e-73
Identity = 123/235 (52.34%), Postives = 168/235 (71.49%), Query Frame = 2

Query:    2 EIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHTRL 706
            ++M+    DL KRLM+KF GE+GLDYGG++RE+ +LLSHEM NP+Y LF+YS  D YTLQINP S VNPEHL+YF F+GR++G+A+FH  ++D  F   FYK +L K ++L DME VD DLH +L W LDNDI G+++ TF V+   +GE    +L P G+ IPVT + K +Y+ L   W+ ++ +E QF A   GFNE+IP  L+  FDE+ELEL++ G+  ID+ DWK +TRL
Sbjct:  426 QVMKMRPKDLWKRLMVKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILDNDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTQDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKELELIVCGLGKIDINDWKSNTRL 660          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: SMUF2_HUMAN (E3 ubiquitin-protein ligase SMURF2 OS=Homo sapiens GN=SMURF2 PE=1 SV=1)

HSP 1 Score: 274.633 bits (701), Expect = 3.571e-73
Identity = 126/235 (53.62%), Postives = 168/235 (71.49%), Query Frame = 2

Query:    2 EIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHTRL 706
            ++M+    DL KRLMIKF GE+GLDYGG++RE+ +LLSHEM NP+Y LF+YS  D YTLQINP S VNPEHL+YF F+GR++G+A+FH  ++D  F   FYK +L K ++L DME VD DLH +L W L+NDI G+++ TF V+   +GE    +L P G+ IPV  ENK +Y+ L   W+ ++ +E QF A   GFNE+IP  L+  FDE+ELEL+I G+  IDV DWK +TRL
Sbjct:  409 QVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRL 643          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: SMUF2_XENLA (E3 ubiquitin-protein ligase SMURF2 OS=Xenopus laevis GN=smurf2 PE=2 SV=1)

HSP 1 Score: 274.248 bits (700), Expect = 4.663e-73
Identity = 124/235 (52.77%), Postives = 168/235 (71.49%), Query Frame = 2

Query:    2 EIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHTRL 706
            ++M+    DL KRLMIKF GE+GLDYGG++RE+ +LLSH+M NP+Y LF+YS  D YTLQINP S VNPEHL+YF F+GR++G+A+FH  ++D  F   FYK +L K ++L DME VD DLH +L W L+NDI G+++ TF V+   +GE    +L P G+ IPVT + K +Y+ L   W+ ++ +E QF A   GFNE+IP  L+  FDE+ELEL+I G+  IDV DWK +TRL
Sbjct:  412 QVMKMRPKDLWKRLMIKFRGEEGLDYGGVAREWLYLLSHDMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHLSYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILENDITGVLDHTFCVEHNAYGELIQHELKPSGKSIPVTEDTKKEYVRLYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKELELIICGLGKIDVSDWKSNTRL 646          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: NEDD4_DROME (E3 ubiquitin-protein ligase Nedd-4 OS=Drosophila melanogaster GN=Nedd4 PE=1 SV=2)

HSP 1 Score: 273.863 bits (699), Expect = 6.090e-73
Identity = 129/225 (57.33%), Postives = 176/225 (78.22%), Query Frame = 2

Query:   29 LKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGV-NPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHT 700
            LK +L ++F+GE GLDYGGL+RE+F+LLS EMFNP+Y LFEYSA DNYTLQIN  SG+ N EHL+YFKFIGR+ G+A++H + LD+FFI  FYKMML+K + L+DME VD + + +L W  +ND   I+ELTF +D++ FG++   +L PGG +I VTNENK +YI+LV EW+ + RV+EQ  +F+ GF  +IP +L+ +FDE ELELL+ GI +IDV+DW+E+T
Sbjct:  676 LKTKLWVEFEGETGLDYGGLAREWFYLLSKEMFNPYYGLFEYSAMDNYTLQINNGSGLCNEEHLSYFKFIGRIAGMAVYHGKLLDAFFIRPFYKMMLQKPIDLKDMESVDTEYYNSLMWIKEND-PRILELTFCLDEDVFGQKSQHELKPGGANIDVTNENKDEYIKLVIEWRFVARVKEQMSSFLDGFGSIIPLNLIKIFDEHELELLMCGIQNIDVKDWRENT 899          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: SMUF1_MOUSE (E3 ubiquitin-protein ligase SMURF1 OS=Mus musculus GN=Smurf1 PE=1 SV=2)

HSP 1 Score: 273.092 bits (697), Expect = 1.039e-72
Identity = 122/235 (51.91%), Postives = 169/235 (71.91%), Query Frame = 2

Query:    2 EIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHTRL 706
            +IM+    DLKKRLM+KF GE+GLDYGG++RE+ +LL HEM NP+Y LF+YS  + YTLQINP S +NP+HL+YF F+GR++GLA+FH  +++  F   FYK +L K + L D+E VD +LH++L W L+NDI  +++ TF V+   FG     +L P GR++PVT ENK +Y+ L   W+ M+ +E QF A   GFNELIP  L+  FD++ELEL+IGG+  ID+ DWK +TRL
Sbjct:  389 QIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRL 623          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: NEDD4_RAT (E3 ubiquitin-protein ligase NEDD4 OS=Rattus norvegicus GN=Nedd4 PE=1 SV=1)

HSP 1 Score: 272.322 bits (695), Expect = 1.772e-72
Identity = 130/230 (56.52%), Postives = 174/230 (75.65%), Query Frame = 2

Query:   20 ASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSA-HDNYTLQINPHSGV-NPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHTR 703
            A  LK RL I+FDGE GLDYGG++RE+FFL+S EMFNP+Y LFEYSA  DNYTLQINP+SG+ N +HL+YFKFIGRV G+A++H + LD FFI  FYKMML+K ++L DME VD + + +L W L+ND   + +L F +D+E FG+    +L  GG ++ VTN+NK +YI LV +W+ + R+++Q  AF  GF ELIP DL+ +FDE ELELL+ G+ D+DV DW+EHT+
Sbjct:  552 ADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATEDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITLHDMESVDSEYYSSLRWILENDPTEL-DLRFIIDEELFGQTHQHELKTGGSEVVVTNKNKKEYIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREHTK 780          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: SMUF1_HUMAN (E3 ubiquitin-protein ligase SMURF1 OS=Homo sapiens GN=SMURF1 PE=1 SV=2)

HSP 1 Score: 270.781 bits (691), Expect = 5.156e-72
Identity = 121/235 (51.49%), Postives = 168/235 (71.49%), Query Frame = 2

Query:    2 EIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHTRL 706
            +IM+    DLKKRLM+KF GE+GLDYGG++RE+ +LL HEM NP+Y LF+YS  + Y LQINP S +NP+HL+YF F+GR++GLA+FH  +++  F   FYK +L K + L D+E VD +LH++L W L+NDI  +++ TF V+   FG     +L P GR++PVT ENK +Y+ L   W+ M+ +E QF A   GFNELIP  L+  FD++ELEL+IGG+  ID+ DWK +TRL
Sbjct:  415 QIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRL 649          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: SMUF1_XENLA (E3 ubiquitin-protein ligase SMURF1 OS=Xenopus laevis GN=smurf1 PE=2 SV=1)

HSP 1 Score: 268.47 bits (685), Expect = 2.559e-71
Identity = 119/235 (50.64%), Postives = 168/235 (71.49%), Query Frame = 2

Query:    2 EIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHTRL 706
            +IM+    DLKKRLM+KF GE+GLDYGG++RE+ +LL HEM NP+Y LF+YS  + YTLQINP S +NP+HL+YF F+GR++GLA+FH  +++  F   FYK +L K + L D+E VD +LH++L W L+NDI  +++ TF V+   FG     +L P G+++ VT ENK +Y+ L   W+ M+ +E QF A   GFNELIP  L+  F+++ELEL+IGG+  ID+ DWK +TRL
Sbjct:  389 QIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITSVLDHTFCVEHNAFGRLLQHELKPNGKNLQVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFEQKELELIIGGLDKIDISDWKANTRL 623          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: PUB2_SCHPO (E3 ubiquitin-protein ligase pub2 OS=Schizosaccharomyces pombe GN=pub2 PE=1 SV=1)

HSP 1 Score: 265.388 bits (677), Expect = 2.166e-70
Identity = 123/232 (53.02%), Postives = 172/232 (74.14%), Query Frame = 2

Query:    5 IMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGIVELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEHT 700
            I + S SD+KK+L+I+F  EDGLDYGG+SREFF++LSH +FNP Y LFEY+  DNY LQI+P S VNP+  +YF+F+GRV+GLAI+HRR+LD  F+  FYK +L+K + L+D++ VDE  + +L W  +ND+D  + L FSV++ +FGE  T+DLIP GR+I V N+NK  Y++ +TE K++   EEQF+A   G NELIP  ++ +F+E EL+ L+ G  DIDV+DWK  T
Sbjct:  334 ISKLSVSDMKKKLLIRFRNEDGLDYGGVSREFFYILSHAIFNPGYSLFEYATDDNYGLQISPLSSVNPDFRSYFRFVGRVMGLAIYHRRYLDVQFVLPFYKRILQKPLCLEDVKDVDEVYYESLKWIKNNDVDESLCLNFSVEENRFGESVTVDLIPNGRNIAVNNQNKMNYLKALTEHKLVTSTEEQFNALKGGLNELIPDSVLQIFNENELDTLLNGKRDIDVQDWKRFT 565          

BLAST of FC931696 vs. ExPASy Swiss-Prot
Match: ITCH_MOUSE (E3 ubiquitin-protein ligase Itchy OS=Mus musculus GN=Itch PE=1 SV=2)

HSP 1 Score: 257.299 bits (656), Expect = 5.899e-68
Identity = 118/233 (50.64%), Postives = 167/233 (71.67%), Query Frame = 2

Query:    2 EIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLDNDIDGI-VELTFSVDDEKFGERRTIDLIPGGRDIPVTNENKPQYIELVTEWKIMKRVEEQFDAFMSGFNELIPPDLVNVFDERELELLIGGIADIDVEDWKEH 697
            +IM  S  DL++RL + F GE+GLDYGG++RE+FFLLSHE+ NP YCLFEY+  DNY LQINP S +NP+HL YF+FIGR + +A+FH +F+D+ F   FYK +L K V L+D+E +D + + +L W  +N+I+   +E+ FSVD E  GE ++ DL P G +I VT ENK +YI +V EW++ + VEEQ  AF  GFNE++P   +  FD +ELE+L+ G+ +ID+ DW+ H
Sbjct:  525 QIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRH 757