FC932651

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1_XENLA (DNA topoisomerase 1 OS=Xenopus laevis GN=top1 PE=2 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 6.243e-46
Identity = 104/221 (47.06%), Postives = 141/221 (63.80%), Query Frame = 2

Query:   44 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAXTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            ++FDF GKDSI+Y N V VE  V+K +  F   K+ +DDLFD+L+T+ LN HL++LM GLTAKVFRTYNASITL   L++ T  D +V  KI  Y RAN+ VAI+CNHQR   KT    M  L  KI+  K  L D R +  ++ K    + +D   K+      +A++R       ++ K+E     +E+ K +ALGTSK+NYLDPRI+VAWCK++ VPI
Sbjct:  581 VEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDELTNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLADARREF-KSAKADAKVRRDEKTKKLVESKKKAVQR----IEEQLMKLEVQATDREENKQIALGTSKLNYLDPRISVAWCKKYGVPI 796          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1_DROME (DNA topoisomerase 1 OS=Drosophila melanogaster GN=Top1 PE=1 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 6.243e-46
Identity = 107/225 (47.56%), Postives = 137/225 (60.89%), Query Frame = 2

Query:   38 NKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTG-DGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDR--AKKGKPPLMKDSDGKRKRNLAPEALERKMAXTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            N + FDF GKDSI+Y N VEVE  V+K +  F   KK+ DDLFD+L+T  LN HLKELM GLTAKVFRTYNAS TL   L+  T     V  K+  Y RAN+ VAI+CNHQR+V K+H   M  L EKI+  +  ++    +      KKGK                   LER       +++K+E     +++ KT+ALGTSK+NYLDPRI+VAWCK+H+VPI
Sbjct:  745 NVVVFDFPGKDSIRYYNEVEVEKRVFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLTDPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYHSRDEKKGK------------------QLER----LRDQLKKLELQETDRDENKTIALGTSKLNYLDPRISVAWCKKHDVPI 947          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1_DICDI (DNA topoisomerase 1 OS=Dictyostelium discoideum GN=top1 PE=3 SV=1)

HSP 1 Score: 181.03 bits (458), Expect = 5.285e-45
Identity = 110/272 (40.44%), Postives = 157/272 (57.72%), Query Frame = 2

Query:    2 TLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAV--KIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGK------------PPLM-------KDSDGKR--------------KRNLAPEA---LERKMAXTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            +L+V +++    N +  DFLGKDS++Y+NTV++    YK +  F  GKK  D LFD L   +LN HLK+ M GL+AKVFRTYNASITL   L+K       ++  KI  Y R N+EVAI+CNHQ+   K  +  MS++ EKI++L+ +    R+ + +  K +            P L+       KD D ++              K    P+A   ++ K+A    +I+K E     K++LKTVALGTSKINYLDPRITVAWCK+++VP+
Sbjct:  599 SLRVEHIKLESNNTITLDFLGKDSMRYLNTVQIREDAYKVLKTFVKGKKPTDLLFDSLTVTQLNNHLKKQMTGLSAKVFRTYNASITLQKELDKMDTKEFQSIDEKILFYNRCNREVAILCNHQKAPPKNLAETMSKIDEKIQELRDLQDLCRIKIGKTPKSQQEDIESREAERLPKLIQLAITNKKDKDKEKTDKEISFDVKAAFEKSRTLPDAKGKIKEKIAKYEEQIKKQEILKTGKDELKTVALGTSKINYLDPRITVAWCKKNKVPV 870          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1M_MOUSE (DNA topoisomerase I, mitochondrial OS=Mus musculus GN=Top1mt PE=2 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 1.538e-44
Identity = 100/221 (45.25%), Postives = 135/221 (61.09%), Query Frame = 2

Query:   44 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAXTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            ++ DFLGKDSI+Y N V VE  V++ +  F   K   DDLFD L T+ LN HL++LM GLTAKVFRTYNAS+TL   L   T  +  V  K+  Y RAN+ VA++CNHQR V KT    M  L +KIE  K  + + +V+L   +K +  L    D K K  L     +R++     ++ ++      KE+ K VALGT+K+NYLDPRI++AWCKR  VP+
Sbjct:  354 VELDFLGKDSIRYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASVTLQEQLRVLTRAEDSVTCKVLAYNRANRAVAVLCNHQRAVPKTFEKSMQTLQKKIETKKAQVAEAQVEL---QKAETDLRMRGDSKPKSFLQK---QRRLLKLEEQLARLCAKATDKEENKQVALGTAKLNYLDPRISIAWCKRFGVPV 568          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1M_RAT (DNA topoisomerase I, mitochondrial OS=Rattus norvegicus GN=Top1mt PE=2 SV=1)

HSP 1 Score: 177.563 bits (449), Expect = 5.844e-44
Identity = 101/221 (45.70%), Postives = 134/221 (60.63%), Query Frame = 2

Query:   44 LKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGT-GDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDLKGVLKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERKMAXTNAKIEKMERDMKTKEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            ++ DFLGKDSI+Y N V VE  V++ +  F   K   DDLFD L T+ LN HL++LM GLTAKVFRTYNASITL   L   T  +  +  K+  Y RAN+ VA++CNHQR + KT    M  L +KIE  K  + + +V+L   +K +  L    D K K  L  +    K+    A++     D   KE+ K VALGT+K+NYLDPRI++AWCKR  VP+
Sbjct:  354 VELDFLGKDSIRYKNHVTVEKLVFQNLQHFMEDKDPRDDLFDALTTSSLNKHLQDLMEGLTAKVFRTYNASITLQEQLRVLTRAEDSLTCKVLAYNRANRAVAVLCNHQRAIPKTFEESMQTLQKKIETKKAQVAEAQVEL---QKAETDLRMRGDSKSKSFLQKQQRLLKLEEQLARLCTKATD---KEENKQVALGTAKLNYLDPRISIAWCKRFGVPV 568          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1_CANAL (DNA topoisomerase 1 OS=Candida albicans GN=TOP1 PE=3 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 4.056e-37
Identity = 105/308 (34.09%), Postives = 157/308 (50.97%), Query Frame = 2

Query:    2 TLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQ-NDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKI-------------------------------------EDLKGV------------LKDLRVDLDRAKKGKPPLMKDSDGKRKRNLAPEALERK----------MAXTNAKIEKMERDMKT--------------KEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            +L+  +V   PPNK+ FD LGKDSI++   VEV+  V+K +  F+   KQ  DDLFD+++ + +N  L+  M GLTAKVFRTYNAS T+   ++    +G VA K+  +  AN+ VAI+CNHQRTVSKTH   + R+ +K+                                     ED++ +             K L  D ++ K    PL+ +SD K K +   E LE++          +   NA +EK+++ ++T              KED   V+LGTSK+NY+DPR+ V + K+ +VPI
Sbjct:  447 SLRYEHVTLKPPNKVIFDLLGKDSIRFYQEVEVDKQVFKNLRIFKKSPKQPGDDLFDRINPSLVNRQLQNYMKGLTAKVFRTYNASKTMQDQIDIIENEGTVAEKVAKFNAANRTVAILCNHQRTVSKTHGDSVQRINDKLKKFMWQKIRLKKMILQLEPKLKKKDSKYFEEIDDLIKEDIEHIHHTIIKRQREQAKKKLERDNEKLKLEGKPLLTESDIKDKLDKIDE-LEKEYQKELKTGKPIVTKNATVEKLKQQIETLENRILNVSIQLKDKEDNSEVSLGTSKMNYIDPRLIVMFSKKFDVPI 753          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1_YEAST (DNA topoisomerase 1 OS=Saccharomyces cerevisiae GN=TOP1 PE=1 SV=2)

HSP 1 Score: 153.68 bits (387), Expect = 9.036e-37
Identity = 107/308 (34.74%), Postives = 161/308 (52.27%), Query Frame = 2

Query:    2 TLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTGKKQ-NDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDL---------------KGVLK----------DLRVD---------LDR-AKKGKPPLMKDSDGKR--KRNLAPEA-LERKMAXTNAKIEKMERDMKT-----------------------------------KEDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            +L+  +V   PPN + FDFLGKDSI++   VEV+  V+K +  F+   KQ    LFD+LD + LN +L+  MPGLTAKVFRTYNAS T+   L+     G VA KI  Y  AN+ VAI+CNHQRTV+K H+  + +   +I++L               K +LK          DL  +         +DR  +K +   ++++D ++  K  L PE+ L+  +   + K ++ E+++KT                                   KE+   V+LGTSKINY+DPR++V +CK+++VPI
Sbjct:  437 SLRYEHVTLKPPNTVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPI 744          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1_SCHPO (DNA topoisomerase 1 OS=Schizosaccharomyces pombe GN=top1 PE=1 SV=2)

HSP 1 Score: 153.68 bits (387), Expect = 9.036e-37
Identity = 107/307 (34.85%), Postives = 160/307 (52.12%), Query Frame = 2

Query:    2 TLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELPVYKAIGQFQTG-KKQNDDLFDKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGMLNKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVSKTHSAQMSRLTEKIEDL---KGVLKDLRVDLD-RAKKGKPPLMKDSDG---------------------KRK-------------RNLAPEA-LERKMAXTNAKIEKMERDMKTK---------------------------------EDLKTVALGTSKINYLDPRITVAWCKRHEVPI 703
            +L+  +V   PP  + FDFLGKDSI+Y N VEV+  V+K +  F+   KK+ D +FD+L T  LN +L  LM GL+AKVFRTYNAS T+   L K   +  +A KI  Y RAN+ VAI+CNHQR+V+K H  QM R  E+I+ L   +  L+ + ++L+ +  K KP L+   +G                     K+K             +++ PE+ LE ++   +   + ++ ++K+K                                 ++ KT ALGTSKINY+DPR+T ++ KR +VPI
Sbjct:  484 SLRYEHVTLKPPRTVVFDFLGKDSIRYYNEVEVDPQVFKNLKIFKRPPKKEGDLIFDRLSTNSLNKYLTSLMDGLSAKVFRTYNASYTMAEELKKMPKNLTLADKILFYNRANRTVAILCNHQRSVTKNHDVQMERFAERIKALQYQRMRLRKMMLNLEPKLAKSKPELLAKEEGITDSWIVKHHETLYELEKEKIKKKFDRENEKLAAEDPKSVLPESELEVRLKAADELKKALDAELKSKKVDPGRSSMEQLEKRLNKLNERINVMRTQMIDKDENKTTALGTSKINYIDPRLTYSFSKREDVPI 790          

BLAST of FC932651 vs. ExPASy Swiss-Prot
Match: TOP1_USTMA (DNA topoisomerase 1 OS=Ustilago maydis GN=TOP1 PE=3 SV=2)

HSP 1 Score: 70.0922 bits (170), Expect = 1.314e-11
Identity = 49/160 (30.63%), Postives = 77/160 (48.12%), Query Frame = 2

Query:    2 TLKVGNVECIPPNKLKFDFLGKDSIQYVNTVEVELP-VYKAIGQFQTG------------KKQNDDLF----------DKLDTAKLNAHLKELMPGLTAKVFRTYNASITLDGML-----------NKGTGDGDVAVKIDVYQRANKEVAIICNHQRTVS 379
            +L+  + +   P+ +  +FLGKDS+++   +++  P V+K I  F               KK +D +F            L    +N  L + M GL+AKVFRTYNAS+T  G+L           N    + +       Y  AN++VAI+CNHQ+TV+
Sbjct:  459 SLRCEHAQIKMPDTIHLEFLGKDSMKFEEDLKITNPDVFKNIAMFLKSNGMKDKSGNYVRKKPSDPIFCAPESGSGKMQPLQPNSVNQFLSKYMKGLSAKVFRTYNASVTFQGLLEQTEEWLKSRPNAAEREINQTNLRLAYNEANRQVAILCNHQKTVN 618