CB290389

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: HUNK_XENTR (Hormonally up-regulated neu tumor-associated kinase homolog OS=Xenopus tropicalis GN=hunk PE=2 SV=1)

HSP 1 Score: 126.716 bits (317), Expect = 1.386e-28
Identity = 70/173 (40.46%), Postives = 100/173 (57.80%), Query Frame = 1

Query:  262 GKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKE-FMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKV-ARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            G Y +GR LG+G+FAKV  G  + TGE VAIKVI+K + KK+ ++ + ++RE  + +++RHPN+ +L +++ T+   ++ ME   GG L  K+  R R+ E  ARKY +QLI AV+  H  GV HR                + DFGLS     L       TQCG+PAY AP
Sbjct:   53 GSYLIGRKLGEGSFAKVREGLHVGTGEKVAIKVIDKKKAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCTGGNLMHKIYERKRIEEHEARKYIRQLILAVEHLHRAGVVHRDLKIENLLLDENNNIKLIDFGLSNCAGILGYTDPFSTQCGSPAYAAP 225          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: PAR1_CAEEL (Serine/threonine-protein kinase par-1 OS=Caenorhabditis elegans GN=par-1 PE=1 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.811e-28
Identity = 69/183 (37.70%), Postives = 108/183 (59.02%), Query Frame = 1

Query:  229 RHMEEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELF-AKVARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            R  +++ HV  GKY++ + +GKG FAKV   K ++TG  VAIK+I+K  L     ++++ RE+ +M+ + HPN+V+L +VM T++ +++ +EY  GGE+F   VA GR++E  AR  F+Q++SAV + HS+ + HR                I+DFG S           L T CG+P Y AP
Sbjct:  159 RRNDQDVHV--GKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPS-SLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFS---NTFSLGNKLDTFCGSPPYAAP 335          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: PAR1_CAEBR (Serine/threonine-protein kinase par-1 OS=Caenorhabditis briggsae GN=par-1 PE=3 SV=1)

HSP 1 Score: 126.331 bits (316), Expect = 1.811e-28
Identity = 69/183 (37.70%), Postives = 108/183 (59.02%), Query Frame = 1

Query:  229 RHMEEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELF-AKVARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            R  +++ HV  GKY++ + +GKG FAKV   K ++TG  VAIK+I+K  L     ++++ RE+ +M+ + HPN+V+L +VM T++ +++ +EY  GGE+F   VA GR++E  AR  F+Q++SAV + HS+ + HR                I+DFG S           L T CG+P Y AP
Sbjct:  117 RRNDQDVHV--GKYKLLKTIGKGNFAKVKLAKHVITGHEVAIKIIDKTALNPS-SLQKLFREVKIMKQLDHPNIVKLYQVMETEQTLYLVLEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYLHSKNIIHRDLKAENLLLDQDMNIKIADFGFS---NTFSLGNKLDTFCGSPPYAAP 293          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: SIK2_HUMAN (Serine/threonine-protein kinase SIK2 OS=Homo sapiens GN=SIK2 PE=1 SV=1)

HSP 1 Score: 125.176 bits (313), Expect = 4.033e-28
Identity = 71/183 (38.80%), Postives = 105/183 (57.38%), Query Frame = 1

Query:  229 RHMEEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKVA-RGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            RH++    V  G Y++   LGKG FA V  G+  +T   VAIK+I+K QL     +E+I RE+ +M+++ HP++++L +VM TK  +++  EY K GE+F  +A  GRL E  AR+ F Q++SAVD+CH R + HR                I+DFG        ++  LL T CG+P Y AP
Sbjct:    8 RHLQRGP-VRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDA-VNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNF---FKSGELLATWCGSPPYAAP 185          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: SIK2_MOUSE (Serine/threonine-protein kinase SIK2 OS=Mus musculus GN=Sik2 PE=1 SV=1)

HSP 1 Score: 124.405 bits (311), Expect = 6.880e-28
Identity = 72/183 (39.34%), Postives = 103/183 (56.28%), Query Frame = 1

Query:  229 RHMEEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKVA-RGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            RH++    V  G Y++   LGKG FA V  G+   T   VAIK+I+K QL     +E+I RE+ +M+++ HP++++L +VM TK  +++  EY K GE+F  +A  GRL E  AR+ F Q++SAVD+CH R V HR                I+DFG        +   LL T CG+P Y AP
Sbjct:    8 RHLQRGP-VRVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDA-VNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNF---FKTGELLATWCGSPPYAAP 185          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: RKIN1_SECCE (Carbon catabolite-derepressing protein kinase OS=Secale cereale GN=RKIN1 PE=2 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 8.986e-28
Identity = 72/174 (41.38%), Postives = 103/174 (59.20%), Query Frame = 1

Query:  268 YEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRL---VRHPNVVELREVMATKKKIFVAMEYVKGGELFAKV-ARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDG-LLHTQCGTPAYVAP 774
            Y +G++LG GTFAKV   +   T   VAIKV+N+ Q++   M E+ KREI ++RL   + HP+++ + EV+ T K IFV MEY + G+L   +  + RL+ED AR+ FQQ+ISAV++CH   V HR                ++DFGLS     + +DG  L T CG+  Y AP
Sbjct:   14 YYLGKILGVGTFAKVIIAEHKHTRHKVAIKVLNRRQMRAPEMEEKAKREIKILRLFIDLIHPHIIRVYEVIVTPKDIFVVMEYCQNGDLLDYILEKRRLQEDEARRTFQQIISAVEYCHRNKVVHRDLKPENLLLDSKYNVKLADFGLS----NVMHDGHFLKTSCGSLNYAAP 183          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MRKC_DICDI (Probable serine/threonine-protein kinase MARK-C OS=Dictyostelium discoideum GN=mrkC PE=3 SV=1)

HSP 1 Score: 124.02 bits (310), Expect = 8.986e-28
Identity = 72/183 (39.34%), Postives = 109/183 (59.56%), Query Frame = 1

Query:  238 EEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKK---IFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            ++ R +  G YE+G+ LG GTF KV  G  + T E+VAIK I  ++L  +   E   REI +M+L+ HPN+V+L +V+  +++    ++ +EYV GGELF   VAR  ++E  ARK+F+Q+ISA+++CH+  + HR                ISDFGLS     ++   LL + CG+P Y AP
Sbjct:   36 KKNRIMHVGSYEVGKTLGNGTFGKVKLGTNICTKENVAIKFIKNNKLSGK-QKETCFREIDIMKLLDHPNIVKLLDVVDKREEEGTTYLIVEYVSGGELFDYIVAREYIKEKEARKFFRQMISAIEYCHANLIVHRDLKPENLLLDSNGDIKISDFGLS---NNIQPGKLLESFCGSPLYAAP 214          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MARK3_HUMAN (MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens GN=MARK3 PE=1 SV=3)

HSP 1 Score: 121.324 bits (303), Expect = 5.824e-27
Identity = 70/203 (34.48%), Postives = 109/203 (53.69%), Query Frame = 1

Query:  238 EEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELF-AKVARGRLREDLARKYFQQ-----------------------LISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +E+ H+  G Y + + +GKG FAKV   + ++TG  VAIK+I+K QL     ++++ RE+ +M+++ HPN+V+L EV+ T+K +++ MEY  GGE+F   VA GR++E  AR  F+Q                       ++SAV +CH + + HR                I+DFG S    +    G L T CG+P Y AP
Sbjct:   48 DEQPHI--GNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPT-SLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQGCQAGQTIKVQVSFDLLSLMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFS---NEFTVGGKLDTFCGSPPYAAP 244          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: SNF1_SCHPO (SNF1-like protein kinase ssp2 OS=Schizosaccharomyces pombe GN=ssp2 PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 2.891e-26
Identity = 65/178 (36.52%), Postives = 103/178 (57.87%), Query Frame = 1

Query:  244 ERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKVA-RGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +RH+  G Y +   LG+G+F KV       T + VA+K I++  LKK  M  +++REIS ++L+RHP++++L +V+ T   I + +EY  GGELF  +  + R+ ED  R++FQQ+I A+++CH   + HR                I+DFGLS +   + +   L T CG+P Y AP
Sbjct:   28 KRHI--GPYIIRETLGEGSFGKVKLATHYKTQQKVALKFISRQLLKKSDMHMRVEREISYLKLLRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAP 199          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: KIN4_YEAST (Serine/threonine-protein kinase KIN4 OS=Saccharomyces cerevisiae GN=KIN4 PE=1 SV=1)

HSP 1 Score: 119.013 bits (297), Expect = 2.891e-26
Identity = 71/198 (35.86%), Postives = 108/198 (54.55%), Query Frame = 1

Query:  202 RQNSNFLRERHMEEERHVLFGKYEMGRLLGKGTFAKVYYG--KQLMTGE---SVAIKVINKDQLKKEFMME-QIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKVAR-GRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            ++N+  L   H  + +H  FG Y +G  LG+G F KV  G  K   + E    VAIK+I +D +KK+   E +I REI+ ++ + HPN++ L EV+   K I + +E+V GGE +  + R  RL+E  A + F QLIS V++ H +G+ HR                I+DFG   + E   ++ L+ T CG+P Y AP
Sbjct:   24 QRNNEILHPIHKNQRKHATFGPYIIGSTLGEGEFGKVKLGWTKASSSNEVPKQVAIKLIRRDTIKKDADKEIKIYREINALKHLTHPNIIYLEEVLQNSKYIGIVLEFVSGGEFYKYIQRKRRLKESSACRLFAQLISGVNYMHYKGLVHRDLKLENLLLDKHENLVITDFGF--VNEFFEDNELMKTSCGSPCYAAP 219