CB290389

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MELK_MOUSE (Maternal embryonic leucine zipper kinase OS=Mus musculus GN=Melk PE=1 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 9.299e-25
Identity = 65/170 (38.24%), Postives = 99/170 (58.24%), Query Frame = 1

Query:  268 YEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            YE+   +G G FAKV     ++TGE VAIK+++K+ L  +  + ++K EI  ++ +RH ++ +L  V+ TK KIF+ +EY  GGELF   +++ RL E+  R  F+Q++SAV + HS+G +HR                + DFGL A P+    D  L T CG+ AY AP
Sbjct:   11 YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSD--LPRVKTEIDALKSLRHQHICQLYHVLETKNKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFDENHKLKLIDFGLCAKPKG-NKDYHLQTCCGSLAYAAP 177          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: SMKY_MOUSE (Sperm motility kinase Y OS=Mus musculus PE=2 SV=1)

HSP 1 Score: 113.62 bits (283), Expect = 1.214e-24
Identity = 64/174 (36.78%), Postives = 98/174 (56.32%), Query Frame = 1

Query:  256 LFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKV-ARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            L+ +Y++ R LG GT+AKV   K  +TG  VA+KV+    LK +   +   +E ++M+ ++HPN+V L +V  TK + ++ ME V+G EL+  + + G + ED AR+ F Q++SAV +CH  G+ HR                I DFGLS    Q++   LL   CG  A+ AP
Sbjct:   24 LYSQYKVVRTLGHGTYAKVLLAKHWLTGTPVAVKVL----LKNKPCFQPAMKEANIMKKIKHPNIVSLLQVFETKTRGYLIMELVEGQELYEYIKSSGHIEEDEARQIFLQILSAVSYCHGLGIVHRDLKPDNIMIDDKGSIKIIDFGLST---QVKPGDLLDEHCGAYAFGAP 190          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MELK_HUMAN (Maternal embryonic leucine zipper kinase OS=Homo sapiens GN=MELK PE=1 SV=3)

HSP 1 Score: 112.849 bits (281), Expect = 2.072e-24
Identity = 65/170 (38.24%), Postives = 98/170 (57.65%), Query Frame = 1

Query:  268 YEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            YE+   +G G FAKV     ++TGE VAIK+++K+ L  +  + +IK EI  ++ +RH ++ +L  V+ T  KIF+ +EY  GGELF   +++ RL E+  R  F+Q++SAV + HS+G +HR                + DFGL A P+    D  L T CG+ AY AP
Sbjct:   11 YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSD--LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKG-NKDYHLQTCCGSLAYAAP 177          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MRKA_DICDI (Probable serine/threonine-protein kinase MARK-A OS=Dictyostelium discoideum GN=mrkA PE=3 SV=1)

HSP 1 Score: 111.694 bits (278), Expect = 4.615e-24
Identity = 62/173 (35.84%), Postives = 97/173 (56.07%), Query Frame = 1

Query:  262 GKYEMGRLLGKGTFAKVYYG-KQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELF-AKVARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            G Y + + +G+G F KV  G  + +  E VAIK+INK +L  E  ++ ++RE+ +M+L+ HPN++ L EV+ T + +++ MEY   GE+    +A G L E  AR +F Q++SA+++CHS+   HR                I DFGLS +         L T CG+P Y +P
Sbjct:  107 GNYLVIKTIGRGQFGKVKLGYHKKIPNEKVAIKIINKGKLDPE-TLKMVQREVRIMKLLHHPNIIRLYEVIETSRALYLIMEYAGEGEVMDFMIAHGVLTESQARTFFTQIVSAINYCHSKRAVHRDLKPENLLLDCNRQIKIIDFGLSNV---FTPGSYLKTFCGSPTYASP 275          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: NUAK2_MOUSE (NUAK family SNF1-like kinase 2 OS=Mus musculus GN=Nuak2 PE=2 SV=2)

HSP 1 Score: 110.923 bits (276), Expect = 7.872e-24
Identity = 68/192 (35.42%), Postives = 100/192 (52.08%), Query Frame = 1

Query:  226 ERHMEEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELRE--------VMATKKKIFVAMEYVKGGELFAKVA-RGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +RH    +H L  +YE    LGKGT+ KV   ++  +G  VAIK I KD++K E  +  I+REI +M  + HP+++ + E        V     KI + MEY   G+L+  ++ R RL E  AR +F+Q++SA+ +CH  G+ HR                I+DFGLS L         L T CG+P Y +P
Sbjct:   45 KRH--HHKHNLRHRYEFLETLGKGTYGKVKKARE-SSGRLVAIKSIRKDKIKDEQDLLHIRREIEIMSSLNHPHIIAIHEVGRSRLVTVFENSSKIVIVMEYASRGDLYDYISERPRLSERDARHFFRQIVSALHYCHQNGIVHRDLKLENILLDANGNIKIADFGLSNL---YHKGKFLQTFCGSPLYASP 230          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MRKB_DICDI (Probable serine/threonine-protein kinase MARK-B OS=Dictyostelium discoideum GN=mrkB PE=3 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 7.872e-24
Identity = 62/174 (35.63%), Postives = 99/174 (56.90%), Query Frame = 1

Query:  262 GKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKK--KIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            G Y +G+ +G GT +KV  G  ++TG+  AIK+    ++K+    ++I+REIS+++ ++H N+++L + +      +I + +E V GGELF   VARGRL E   RK+F+Q++  + +CHS  V HR                ISDFG S +   ++   LL T CG+P Y  P
Sbjct:   63 GNYLLGKTIGSGTSSKVKIGTNILTGKQYAIKITKPKRIKER---KEIEREISILKRLKHDNIIQLHDAIYEDDVGRICLILELVSGGELFDYIVARGRLSEKEGRKFFRQMLCGLIYCHSNMVCHRDLKLENLLVDEDGNLKISDFGYSNI---IKPGNLLSTFCGSPVYAPP 230          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: SIK1_MOUSE (Serine/threonine-protein kinase SIK1 OS=Mus musculus GN=Sik1 PE=1 SV=2)

HSP 1 Score: 110.538 bits (275), Expect = 1.028e-23
Identity = 61/179 (34.08%), Postives = 101/179 (56.42%), Query Frame = 1

Query:  241 EERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKV-ARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +++ +  G Y++ R LGKG FA V   +  +T   VAIK+I+K +L     +E+I RE+ +M+L+ HPN+++L +VM TK  +++  E+ K GE+F  + + G L E+ AR+ F Q++SAV++CH+  + HR                ++DFG        +    L T  G+P Y AP
Sbjct:   18 QQKPLRVGFYDVERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSS-NLEKIYREVQLMKLLNHPNIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARQKFWQILSAVEYCHNHHIVHRDLKTENLLLDSNMDIKLADFGFGNF---YKPGEPLSTCVGSPPYAAP 192          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MYLKA_DICDI (Myosin light chain kinase A OS=Dictyostelium discoideum GN=mlkA PE=1 SV=2)

HSP 1 Score: 110.538 bits (275), Expect = 1.028e-23
Identity = 64/173 (36.99%), Postives = 97/173 (56.07%), Query Frame = 1

Query:  268 YEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHR---XXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            YE    LG+G F+ VY G+   T +  AIKVINK +L K++  + +K E+ +++ V HPN++ L+E+  T +K+++ ME V GGELF K V +G   E  A    ++++SAV + H   + HR                   I+DFGLS +  Q     ++ T CGTP+YVAP
Sbjct:    8 YEFKEELGRGAFSIVYLGENKQTKQRYAIKVINKSELGKDYE-KNLKMEVDILKKVNHPNIIALKELFDTPEKLYLVMELVTGGELFDKIVEKGSYSEADAANLVKKIVSAVGYLHGLNIVHRDLKPENLLLKSKENHLEVAIADFGLSKIIGQTL---VMQTACGTPSYVAP 176          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MYLKG_DICDI (Probable myosin light chain kinase DDB_G0275057 OS=Dictyostelium discoideum GN=DDB_G0275057 PE=3 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 1.343e-23
Identity = 66/173 (38.15%), Postives = 97/173 (56.07%), Query Frame = 1

Query:  268 YEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHR---XXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            Y +G+ LG+G F+ V  G +  T + VA+K I K  +KK+ + EQ++REI +M+ V+H NV+ L+E+  +   + + ME V GGELF K V RG   E  AR   +Q+ + V++ HS+G++HR                   I+DFGLS +         L T CGTP YVAP
Sbjct:   56 YVVGKELGRGAFSVVREGTRKTTSDKVALKYIEKKFVKKKHI-EQLRREIDIMKKVKHENVLSLKEIFESDSHLTLVMELVTGGELFYKIVERGSFTEKGARNVVRQVCAGVEYLHSQGIAHRDLKPENLLCNGEGEDMTIKIADFGLSKI---FGTGEALETSCGTPDYVAP 224          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: FHKC_DICDI (Probable serine/threonine-protein kinase fhkC OS=Dictyostelium discoideum GN=fhkC PE=3 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 2.991e-23
Identity = 67/199 (33.67%), Postives = 109/199 (54.77%), Query Frame = 1

Query:  214 NFLRERHMEEERHVLFG----KYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQL-----KKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHR--XXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +F+ +   EE++ +  G    KY++  +LG G FA V  G +  TG   AIK+I+K ++     +K+ +M+    E++V+  V+H N++ ++EV  T+K +++ +E V GGELF K V+  + +ED  R   +QL  +V + HS G++HR                  ISDFGLS   ++      + T CGTP YVAP
Sbjct:  196 SFIYQDCFEEQKEMEQGGPQQKYDLREVLGTGNFASVRLGVEKETGNKYAIKIIDKKKMSMTSKRKDSLMD----EVNVLTKVKHQNIISIKEVFETQKNLYLVLELVTGGELFDKIVSERKFQEDTCRYILKQLCDSVRYLHSNGIAHRDLKPENILLATPNSFLLKISDFGLSRAMDE---GTYMKTMCGTPQYVAP 387