CB290389

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MARK1_MOUSE (Serine/threonine-protein kinase MARK1 OS=Mus musculus GN=Mark1 PE=1 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 4.309e-30
Identity = 68/180 (37.78%), Postives = 108/180 (60.00%), Query Frame = 1

Query:  238 EEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELF-AKVARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +E+ H+  G Y + + +GKG FAKV   + ++TG  VA+K+I+K QL     ++++ RE+ +M+++ HPN+V+L EV+ T+K +++ MEY  GGE+F   VA GR++E  AR  F+Q++SAV +CH + + HR                I+DFG S    +      L T CG+P Y AP
Sbjct:   52 DEQPHI--GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT-SLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKCIVHRDLKAENLLLDADMNIKIADFGFS---NEFTVGNKLDTFCGSPPYAAP 225          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: MARK1_HUMAN (Serine/threonine-protein kinase MARK1 OS=Homo sapiens GN=MARK1 PE=1 SV=2)

HSP 1 Score: 131.724 bits (330), Expect = 4.309e-30
Identity = 68/180 (37.78%), Postives = 108/180 (60.00%), Query Frame = 1

Query:  238 EEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELF-AKVARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +E+ H+  G Y + + +GKG FAKV   + ++TG  VA+K+I+K QL     ++++ RE+ +M+++ HPN+V+L EV+ T+K +++ MEY  GGE+F   VA GR++E  AR  F+Q++SAV +CH + + HR                I+DFG S    +      L T CG+P Y AP
Sbjct:   52 DEQPHI--GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPT-SLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFS---NEFTVGNKLDTFCGSPPYAAP 225          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: BRSK2_MOUSE (BR serine/threonine-protein kinase 2 OS=Mus musculus GN=Brsk2 PE=1 SV=2)

HSP 1 Score: 131.724 bits (330), Expect = 4.309e-30
Identity = 67/172 (38.95%), Postives = 106/172 (61.63%), Query Frame = 1

Query:  262 GKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELF-AKVARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            G Y + + LGKG    V  G   +T + VAIK++N+++L +  +M+ ++REI++++L+ HP+V++L +V   KK +++ +E+V GGELF   V +GRL    ARK+F+Q+ISA+DFCHS  + HR                I+DFG+++L      D LL T CG+P Y  P
Sbjct:   18 GPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSESVLMK-VEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNNIRIADFGMASLQV---GDSLLETSCGSPHYACP 185          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: HUNK_PANTR (Hormonally up-regulated neu tumor-associated kinase OS=Pan troglodytes GN=HUNK PE=3 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 5.628e-30
Identity = 74/187 (39.57%), Postives = 108/187 (57.75%), Query Frame = 1

Query:  223 RERHMEEERHVLFGKYEMG-RLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKE-FMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKV-ARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            RER  + + H   G Y +G R LG+G+FAKV  G  ++TGE VAIKVI+K + KK+ ++ + ++RE  + +++RHPN+ +L +++ T+   ++ ME   GG L  K+  + RL E  AR+Y +QLISAV+  H  GV HR                + DFGLS     L       TQCG+PAY AP
Sbjct:   46 RERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAP 232          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: HUNK_HUMAN (Hormonally up-regulated neu tumor-associated kinase OS=Homo sapiens GN=HUNK PE=1 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 5.628e-30
Identity = 74/187 (39.57%), Postives = 108/187 (57.75%), Query Frame = 1

Query:  223 RERHMEEERHVLFGKYEMG-RLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKE-FMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKV-ARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            RER  + + H   G Y +G R LG+G+FAKV  G  ++TGE VAIKVI+K + KK+ ++ + ++RE  + +++RHPN+ +L +++ T+   ++ ME   GG L  K+  + RL E  AR+Y +QLISAV+  H  GV HR                + DFGLS     L       TQCG+PAY AP
Sbjct:   46 RERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAP 232          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: NUAK1_MOUSE (NUAK family SNF1-like kinase 1 OS=Mus musculus GN=Nuak1 PE=2 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 7.351e-30
Identity = 73/184 (39.67%), Postives = 102/184 (55.43%), Query Frame = 1

Query:  226 ERHMEEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKVA-RGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +RH    +H L  +YE+   LGKGT+ KV    +  +G  VAIK I KD++K E  M  I+REI +M  + HP+++ + EV   K KI + MEY   GEL+  ++ R RL E   R +F+Q++SAV +CH  GV HR                I+DFGLS L    + D  L T CG+P Y +P
Sbjct:   44 KRH--HHKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDELDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNL---YQKDKFLQTFCGSPLYASP 222          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: HUNK_MOUSE (Hormonally up-regulated neu tumor-associated kinase OS=Mus musculus GN=Hunk PE=2 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.254e-29
Identity = 75/191 (39.27%), Postives = 109/191 (57.07%), Query Frame = 1

Query:  211 SNFLRERHMEEERHVLFGKYEMG-RLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKE-FMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKV-ARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            S   RER  + + H   G Y +G R LG+G+FAKV  G  ++TGE VAIKVI+K + KK+ ++ + ++RE  + +++RHPN+ +L +++ T+   ++ ME   GG L  K+  + RL E  AR+Y +QLISAV+  H  GV HR                + DFGLS     L       TQCG+PAY AP
Sbjct:   42 SGVSRERLRDFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRREGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLDEAEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYAAP 232          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: SNF1_CANTR (Carbon catabolite-derepressing protein kinase OS=Candida tropicalis GN=SNF1 PE=3 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 1.638e-29
Identity = 67/172 (38.95%), Postives = 109/172 (63.37%), Query Frame = 1

Query:  262 GKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            G+Y++ + LG+G+F KV   + + TG+ VA+K+IN+  L K  M  +++REIS +RL+RHP++++L +V+ +K +I + +E+  G ELF   V RG++ ED AR++FQQ+I+AV++CH   + HR                I+DFGLS +   + +   L T CG+P Y AP
Sbjct:   50 GRYQIIKTLGEGSFGKVKLAQHVGTGQKVALKIINRKTLAKSDMQGRVEREISYLRLLRHPHIIKLYDVIKSKDEIIMVIEFA-GKELFDYIVQRGKMPEDEARRFFQQIIAAVEYCHRHKIVHRDLKPENLLLDDQLNVKIADFGLSNI---MTDGNFLKTSCGSPNYAAP 217          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: SIK3_DANRE (Serine/threonine-protein kinase SIK3 homolog OS=Danio rerio GN=zgc:66101 PE=2 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 1.638e-29
Identity = 70/172 (40.70%), Postives = 102/172 (59.30%), Query Frame = 1

Query:  262 GKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAK-VARGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            G YEM R +GKG FA V     ++T   VAIK+++K QL  E  +++I RE+ +M+++RHP+++ L +VM T++ I++  EY  GGE+F   VA GR+ E  AR+ F+Q+++AV FCH R + HR                I+DFG S L        LL T CG+P Y AP
Sbjct:   57 GYYEMERTIGKGNFAVVKLATHMITKAKVAIKIVDKTQLDDE-NLKKIFREVQIMKMLRHPHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKDARRKFKQIVAAVYFCHCRSIVHRDLKAENLLLDHNLNIKIADFGFSNL---FSRGQLLKTWCGSPPYAAP 224          

BLAST of CB290389 vs. ExPASy Swiss-Prot
Match: NUAK1_HUMAN (NUAK family SNF1-like kinase 1 OS=Homo sapiens GN=NUAK1 PE=1 SV=1)

HSP 1 Score: 129.798 bits (325), Expect = 1.638e-29
Identity = 73/184 (39.67%), Postives = 102/184 (55.43%), Query Frame = 1

Query:  226 ERHMEEERHVLFGKYEMGRLLGKGTFAKVYYGKQLMTGESVAIKVINKDQLKKEFMMEQIKREISVMRLVRHPNVVELREVMATKKKIFVAMEYVKGGELFAKVA-RGRLREDLARKYFQQLISAVDFCHSRGVSHRXXXXXXXXXXXXXXXXISDFGLSALPEQLRNDGLLHTQCGTPAYVAP 774
            +RH    +H L  +YE+   LGKGT+ KV    +  +G  VAIK I KD++K E  M  I+REI +M  + HP+++ + EV   K KI + MEY   GEL+  ++ R RL E   R +F+Q++SAV +CH  GV HR                I+DFGLS L    + D  L T CG+P Y +P
Sbjct:   43 KRH--HHKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNL---YQKDKFLQTFCGSPLYASP 221