CB294024

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP17A_PAPHU (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Papio hamadryas ursinus GN=CYP17A1 PE=1 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 9.314e-18
Identity = 53/187 (28.34%), Postives = 95/187 (50.80%), Query Frame = -2

Query:  164 INEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFRYLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFEL-LPPPGQ 721
            ++++++L  + +I  A +ETT   ++W +A L+++P+++KKL   +D  +G     T  D ++L  L+A I+E LR+R   P+L+PH    D+ +G + V   + +++N W L +N  +W +             +  +       YLPFG G RSC                L+Q F+L +P  GQ
Sbjct:  287 LSDNHILTTIGDIFGAGVETTTSVVKWIVAFLLHNPQVKKKLYEGIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQ-PDQFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQ 472          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP17A_MOUSE (Steroid 17-alpha-hydroxylase/17,20 lyase OS=Mus musculus GN=Cyp17a1 PE=2 SV=1)

HSP 1 Score: 90.8929 bits (224), Expect = 9.314e-18
Identity = 56/197 (28.43%), Postives = 98/197 (49.75%), Query Frame = -2

Query:  251 KSMSNESLKCAIDHILDAQTKGEIN------------EDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDF-----RYLPFGVGRRSC 790
            +  ++ESL    D ++ A+   E N            + ++L  V +I  A IETT   + W +A LV++PE+++K++ E+D  +G     +  D   L  L+A I+E LR+R   PLL+PH    D+ +G + +P ++ +++N W L ++  +W +               ++  G+        YLPFG G RSC
Sbjct:  251 EKFNSESLSSLTDILIQAKMNAENNNTGEGQDPSVFSDKHILVTVGDIFGAGIETTSSVLNWILAFLVHNPEVKRKIQKEIDQYVGFSRTPSFNDRTHLLMLEATIREVLRIRPVAPLLIPHKANIDSSIGEFAIPKDTHVIINLWALHHDKNEWDQPDRFMPERF------LDPTGSHLITPTPSYLPFGAGPRSC 441          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP1A1_SPAAU (Cytochrome P450 1A1 OS=Sparus aurata GN=cyp1a1 PE=2 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.216e-17
Identity = 54/206 (26.21%), Postives = 91/206 (44.17%), Query Frame = -2

Query:  137 DHILDAQTKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFRYLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFELLPPPGQSKIDTAEKG 754
            D  LD  +  +++++ V+ IV ++  A  +T   ++ W +  LV +PEIQ++L  E+   +G        D  KLP+L+A I E  R    +P  +PH +  D  L GY +P ++ + +N W + ++P  WK             +          + + FG+G+R C                LVQN      PG+    T E G
Sbjct:  296 DRKLDENSNVQMSDEKVVGIVNDLFGAGFDTISTALSWSVMYLVAYPEIQERLYQEMKESVGLDRTPCLSDKPKLPFLEAFILEIFRHSSFLPFTIPHCSSKDTSLNGYFIPKDTCVFINQWQINHDPELWKDPSSFNPDRFLNTDGTELNKLEGEKMMVFGLGKRRCIGEVIARNEVFLFLAILVQNLRFHAKPGEPLDMTPEYG 501          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP1A1_MICTO (Cytochrome P450 1A1 OS=Microgadus tomcod GN=cyp1a1 PE=2 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.216e-17
Identity = 53/206 (25.73%), Postives = 90/206 (43.69%), Query Frame = -2

Query:  137 DHILDAQTKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFRYLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFELLPPPGQSKIDTAEKG 754
            D  LD  +  +++++ ++ IV ++  A  +T   ++ W +  LV HPEIQ++L  E+   +G        D H LP L+A I E  R    +P  +PH    D  L GY +P ++ + +N W + ++P  WK+            ++         + + FG+G+R C                LVQ       PG+    T E G
Sbjct:  292 DRKLDENSNIQMSDEKIVGIVNDLFGAGFDTVSTALSWSVMYLVAHPEIQERLHQEIKDKVGLSRSPVLTDRHNLPILEAFIFEIFRHSSFLPFTIPHCATKDTSLDGYFIPKDTCVFINQWQINHDPELWKEPSTFNPDRFLSADASELNKLAGEKVMLFGMGKRRCIGEMVARNEVFLFLAILVQRLTFHAVPGEPLDMTPEYG 497          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP1A2_RABIT (Cytochrome P450 1A2 OS=Oryctolagus cuniculus GN=CYP1A2 PE=1 SV=3)

HSP 1 Score: 90.1225 bits (222), Expect = 1.589e-17
Identity = 51/187 (27.27%), Postives = 81/187 (43.32%), Query Frame = -2

Query:  167 GEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFRYLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFELLPPPG 727
            G I ++ ++ +V +I  A  +T   ++ W +  LV +P  Q+K++ ELD V+G   Q    D  +LPYL+A I E  R    +P  +PH    D  L G+ +P E  I +N W + ++P  W              +          +   FG+G+R C                L+Q  E   PPG
Sbjct:  300 GLIPQEKIVNLVNDIFGAGFDTITTALSWSLMYLVTNPRRQRKIQEELDAVVGRARQPRLSDRPQLPYLEAFILELFRHTSFVPFTIPHSTTRDTTLNGFHIPKECCIFINQWQINHDPQLWGDPEEFRPERFLTADGAAINKPLSEKVTLFGLGKRRCIGETLARWEVFLFLAILLQRLEFSVPPG 486          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP1A1_SHEEP (Cytochrome P450 1A1 OS=Ovis aries GN=CYP1A1 PE=2 SV=1)

HSP 1 Score: 90.1225 bits (222), Expect = 1.589e-17
Identity = 47/168 (27.98%), Postives = 82/168 (48.81%), Query Frame = -2

Query:  251 DHILDAQTKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFRYLPFGVGRRSC 754
            D  LD     +++++ ++ +V ++  A  +T   +I W +  LV  P +QKK++ ELDTV+G        D  +LPYL+A I ET R    +P  +PH    D  L G+ +P    + VN W + ++   W+             +  V    ++ + + FG+G+R C
Sbjct:  298 DKRLDENANIQLSDEKIINVVMDLFGAGFDTVTTAISWSLLYLVTSPRVQKKIQEELDTVIGRARWPQLSDRPQLPYLEAFILETFRHSSFVPFTIPHSTTRDTNLNGFYIPKGXCVFVNQWQINHDQKLWEDPSEFRPERFLTTDGTVNKVLSE-KVIIFGLGKRQC 464          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP2D6_PANTR (Cytochrome P450 2D6 OS=Pan troglodytes GN=CYP2D6 PE=3 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 2.710e-17
Identity = 51/194 (26.29%), Postives = 93/194 (47.94%), Query Frame = -2

Query:  158 KGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFR---YLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFELLPPPGQSK 730
            +   N++N+  +V ++  A I TT  ++ WG+  ++ HP++Q++++ E+D V+G   +    D  ++PY  AVI E  R    +PL V HM   D ++ G+ +P  + +  N   +  + A W+K               ++A G+  +   +LPF  GRR+C                L+Q+F    P GQ +
Sbjct:  287 ESSFNDENLRIVVADLFSAGIVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQARMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLFTNLSSVLKDKAVWEKPFRFHPEHF------LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP1A1_FELCA (Cytochrome P450 1A1 OS=Felis catus GN=CYP1A1 PE=2 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 2.710e-17
Identity = 52/201 (25.87%), Postives = 92/201 (45.77%), Query Frame = -2

Query:  152 DHILDAQTKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFRYLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFELLPPPGQSKID 754
            D  LD     +++++ ++ +V ++  A  +T   +I W +  LV  P +Q+K++ ELDTV+G   Q    D  +LPY++A I E  R    +P  +PH    D  L G+ +P E  + VN W + ++   W              +  +    ++ + + FG+G+R C                L+Q  E   P G +K+D
Sbjct:  296 DKRLDENANIQLSDEKIVNVVSDLFGAGFDTVTTAISWCLMYLVTSPNVQEKIQKELDTVIGRERQPRLSDRLQLPYMEAFILEMFRHTSFVPFTIPHSTTKDTSLSGFYIPKERCVFVNQWQINHDQKLWGDPSEFRPERFLTPDGTINKALSE-KVILFGLGKRKCIGETIARLEVFLFLAILLQQVEFSVPQG-TKVD 494          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP2DH_MACFA (Cytochrome P450 2D17 OS=Macaca fascicularis GN=CYP2D17 PE=2 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 4.623e-17
Identity = 52/194 (26.80%), Postives = 92/194 (47.42%), Query Frame = -2

Query:  158 KGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFR---YLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFELLPPPGQSK 730
            +   NE+N+  +V ++  A + TT  ++ WG+  ++ HP++Q++++ E+D V+G   +    D  ++PY  AVI E  R    +PL V HM   D +L G+ +P  + +  N   +  + A W+K               ++A G+  +   +LPF  GRR+C                L+Q F    P GQ +
Sbjct:  287 ESSFNEENLRMVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQARMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIELQGFLIPKGTTLFTNLSSVLKDEAVWEKPFRFHPEHF------LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQPR 474          

BLAST of CB294024 vs. ExPASy Swiss-Prot
Match: CP2D6_PANPA (Cytochrome P450 2D6 OS=Pan paniscus GN=CYP2D6 PE=3 SV=1)

HSP 1 Score: 88.1965 bits (217), Expect = 6.037e-17
Identity = 50/194 (25.77%), Postives = 93/194 (47.94%), Query Frame = -2

Query:  158 KGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRNELDTVLGPGHQITEPDTHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDAKLGGYDVPAESKILVNAWWLANNPAQWKKXXXXXXXXXXXXESKVEANGNDFR---YLPFGVGRRSCPXXXXXXXXXXXXXGRLVQNFELLPPPGQSK 730
            +   N++N+  +V ++  A + TT  ++ WG+  ++ HP++Q++++ E+D V+G   +    D  ++PY  AVI E  R    +PL V HM   D ++ G+ +P  + +  N   +  + A W+K               ++A G+  +   +LPF  GRR+C                L+Q+F    P GQ +
Sbjct:  287 ESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQARMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLFTNLSSVLKDEAVWEKPFRFHPEHF------LDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPR 474