CF417199

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDKL2_MACFA (Cyclin-dependent kinase-like 2 OS=Macaca fascicularis GN=CDKL2 PE=2 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 1.231e-26
Identity = 66/203 (32.51%), Postives = 95/203 (46.80%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRL-LCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLD----TDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            MEKYE L  VGEG+YG V K ++K TG++VA+KK     D++ +   A+RE+ LL+ L     V  L +C +                         K   YLVFE++D     DL+ F         P  L   ++Q +L+Q+  G+  CHSH ++HRD+KP+N               G  R    P + YT  + T WYR
Sbjct:    1 MEKYENLGLVGEGSYGMVVKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKK-------------------------KKRWYLVFEFVDHTILDDLELF---------PNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPEN-ILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYR 168          

HSP 2 Score: 38.891 bits (89), Expect = 1.231e-26
Identity = 14/27 (51.85%), Postives = 20/27 (74.07%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APE+L+G   Y  AVD+W++GC+  EM
Sbjct:  169 APELLVGDVKYGKAVDVWAIGCLVTEM 195          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDKL2_PONAB (Cyclin-dependent kinase-like 2 OS=Pongo abelii GN=CDKL2 PE=2 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 1.234e-26
Identity = 66/203 (32.51%), Postives = 95/203 (46.80%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRL-LCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLD----TDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            MEKYE L  VGEG+YG V K ++K TG++VA+KK     D++ +   A+RE+ LL+ L     V  L +C +                         K   YLVFE++D     DL+ F         P  L   ++Q +L+Q+  G+  CHSH ++HRD+KP+N               G  R    P + YT  + T WYR
Sbjct:    1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKK-------------------------KKRWYLVFEFVDHTILDDLELF---------PNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPEN-ILVSKSGVVKLCDFGFARTLAAPGEVYTDYVATRWYR 168          

HSP 2 Score: 38.891 bits (89), Expect = 1.234e-26
Identity = 14/27 (51.85%), Postives = 20/27 (74.07%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APE+L+G   Y  AVD+W++GC+  EM
Sbjct:  169 APELLVGDVKYGKAVDVWAIGCLVTEM 195          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDKL2_HUMAN (Cyclin-dependent kinase-like 2 OS=Homo sapiens GN=CDKL2 PE=2 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 1.234e-26
Identity = 66/203 (32.51%), Postives = 95/203 (46.80%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRL-LCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLD----TDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            MEKYE L  VGEG+YG V K ++K TG++VA+KK     D++ +   A+RE+ LL+ L     V  L +C +                         K   YLVFE++D     DL+ F         P  L   ++Q +L+Q+  G+  CHSH ++HRD+KP+N               G  R    P + YT  + T WYR
Sbjct:    1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKK-------------------------KKRWYLVFEFVDHTILDDLELF---------PNGLDYQVVQKYLFQIINGIGFCHSHNIIHRDIKPEN-ILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYR 168          

HSP 2 Score: 38.891 bits (89), Expect = 1.234e-26
Identity = 14/27 (51.85%), Postives = 20/27 (74.07%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APE+L+G   Y  AVD+W++GC+  EM
Sbjct:  169 APELLVGDVKYGKAVDVWAIGCLVTEM 195          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDKL2_RABIT (Cyclin-dependent kinase-like 2 OS=Oryctolagus cuniculus GN=CDKL2 PE=2 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 1.602e-26
Identity = 65/203 (32.02%), Postives = 95/203 (46.80%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRL-LCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLD----TDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            MEKYE L  VGEG+YG V K ++K +G++VA+KK     D++ +   A+RE+ LL+ L     V  L +C +                         K   YLVFE++D     DL+ F         P  L   ++Q +L+Q+  G+  CHSH ++HRD+KP+N               G  R    P + YT  + T WYR
Sbjct:    1 MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKK-------------------------KKRWYLVFEFVDHTILDDLELF---------PNGLDDQVVQKYLFQIINGIGFCHSHNIIHRDIKPEN-ILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYR 168          

HSP 2 Score: 39.2762 bits (90), Expect = 1.602e-26
Identity = 14/28 (50.00%), Postives = 21/28 (75.00%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+L+G   Y  AVD+W++GC+  EM+
Sbjct:  169 APELLVGDVKYGKAVDVWAIGCLVTEML 196          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK7_DICDI (Cell division protein kinase 7 OS=Dictyostelium discoideum GN=cdk7 PE=2 SV=2)

HSP 1 Score: 95.9005 bits (237), Expect = 1.614e-26
Identity = 72/202 (35.64%), Postives = 101/202 (50.00%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTR----LEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M+KY     +GEGTYG V +A  KATGQ+VA+KK R        ++GI  +A+RE+ +LQ L     VV LL +                   FA     KSN+YLVFE +  DL++ I+          L P  I+S++  L +G+  CH + VLHRDLKP N               GL R +  P K ++ + VT++YR
Sbjct:    1 MDKYNIEALIGEGTYGVVSRATVKATGQIVAIKKIRKILIQNQTDDGINFSAIREIKILQELKHD-NVVNLLDI-------------------FA----HKSNVYLVFELMQWDLQEVIED-----KSIILKPADIKSYMKMLLQGIEACHRNWVLHRDLKPNN-LLMSINGDLKLADFGLARQYGSPNKVFSPQAVTIFYR 172          

HSP 2 Score: 43.8986 bits (102), Expect = 1.614e-26
Identity = 17/30 (56.67%), Postives = 24/30 (80.00%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKR 690
            APE+L G+  Y  +VD+WS+GCIFAE++ R
Sbjct:  173 APELLFGAKSYGPSVDIWSIGCIFAELMLR 202          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: Y823_ENCCU (Probable cell division protein kinase ECU08_0230 OS=Encephalitozoon cuniculi GN=ECU08_0230 PE=3 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 2.752e-26
Identity = 69/198 (34.85%), Postives = 100/198 (50.51%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            M +Y     +G GTYG+VY+A D  T + VALK+ RL  ++EG+P TALRE+S+L+ LS    ++ L+ + H D+ L                        +VF ++D +LKK+I  +  G N        I   + QL  GV + H   V+HRDLKPQN               GL R+  + +  Y+ E+VTLWYR
Sbjct:    1 MTRYILGALIGSGTYGEVYEAIDTETKEKVALKRIRLN-EKEGMPGTALREISILKKLSHR-NIISLVSIIHTDALLT-----------------------MVFPFIDYELKKYIGMN-TGKN--------IMELVNQLICGVHYLHRMNVVHRDLKPQN-ILVTSDGVLKIADFGLSRSLEIRVPPYSSEVVTLWYR 163          

HSP 2 Score: 40.4318 bits (93), Expect = 2.752e-26
Identity = 16/28 (57.14%), Postives = 22/28 (78.57%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            +PE+L+GST Y   VD+WS+GCI  EM+
Sbjct:  164 SPELLMGSTSYRFYVDIWSLGCIIYEMI 191          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK15_MOUSE (Cell division protein kinase 15 OS=Mus musculus GN=Cdk15 PE=2 SV=2)

HSP 1 Score: 118.627 bits (296), Expect = 3.142e-26
Identity = 76/195 (38.97%), Postives = 103/195 (52.82%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            Y  LEK+GEG+Y KVYK   +  GQLVALK   +   EEG+P TA+RE SLL+ L  +  +V L  + H                        K  L  VFEY+ TDL +++  H     P  L P  ++ F++QL +G+A+ H   VLHRDLKPQN               GL RA ++P ++Y+ E+VTLWYR
Sbjct:  101 YLNLEKLGEGSYAKVYKGISRINGQLVALKVISMNA-EEGVPFTAIREASLLKGLKHA-NIVLLHDIVHT-----------------------KETLTFVFEYMHTDLAQYMSQH-----PGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQN-LLLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYR 264          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: SSN3_COCIM (Serine/threonine-protein kinase SSN3 OS=Coccidioides immitis GN=SSN3 PE=3 SV=2)

HSP 1 Score: 86.6557 bits (213), Expect = 6.000e-26
Identity = 68/206 (33.01%), Postives = 99/206 (48.06%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKAKDK-ATGQLVALKKTRLEMDEE-----GIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSY---THEIVTLWYR 599
            EKY  +  +  GTYG+VYKAK +   G   A+KK + + + E     G+  +A+RE+SL   L+    VVRL     V++ L+                     +Y+VFEY + DL + I  H + P    +P  +++S L+QL  G+ + HS  V+HRDLKP N               GL R F  PL S       +VT+WYR
Sbjct:   98 EKYLIVGFISSGTYGRVYKAKGRDGVGGDFAIKKFKPDKEGEKVEYTGLSQSAIREISLCTELNHP-NVVRL-----VETILEDKC------------------VYMVFEYTEHDLLQIIHHHTQ-PQRHAIPAPMVKSILFQLLNGLLYLHSQWVMHRDLKPAN-ILVTSKGAVRIGDLGLARVFKKPLNSLFSGDKVVVTIWYR 277          

HSP 2 Score: 51.2174 bits (121), Expect = 6.000e-26
Identity = 20/28 (71.43%), Postives = 27/28 (96.43%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLG+ HY+TAVD+W+VGCIFAE++
Sbjct:  278 APELLLGARHYTTAVDLWAVGCIFAELL 305          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK4_RAT (Cell division protein kinase 4 OS=Rattus norvegicus GN=Cdk4 PE=2 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 6.052e-26
Identity = 67/202 (33.17%), Postives = 101/202 (50.00%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEE---GIPPTALREVSLLQMLS--QSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKS-NLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            +YE + ++G G YG VYKA+D  +G  VALK  R+        G+P + +REV+LL+ L   +   VVRL+ V                    ATS   +   + LVFE++D DL+ ++D   K P P  LP   I+  + Q   G+   H++ ++HRDLKP+N               GL R ++  + + T  +VTLWYR
Sbjct:    5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDV-------------------CATSRTDRDIKVTLVFEHIDQDLRTYLD---KAP-PPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPEN-ILVTSNGTVKLADFGLARIYSYQM-ALTPVVVTLWYR 181          

HSP 2 Score: 48.9062 bits (115), Expect = 6.052e-26
Identity = 24/31 (77.42%), Postives = 27/31 (87.10%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APEVLL ST Y+T VDMWSVGCIFAEM +R+
Sbjct:  182 APEVLLQST-YATPVDMWSVGCIFAEMFRRK 211          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK4_MOUSE (Cell division protein kinase 4 OS=Mus musculus GN=Cdk4 PE=1 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 6.052e-26
Identity = 67/202 (33.17%), Postives = 101/202 (50.00%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEE---GIPPTALREVSLLQMLS--QSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKS-NLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            +YE + ++G G YG VYKA+D  +G  VALK  R+        G+P + +REV+LL+ L   +   VVRL+ V                    ATS   +   + LVFE++D DL+ ++D   K P P  LP   I+  + Q   G+   H++ ++HRDLKP+N               GL R ++  + + T  +VTLWYR
Sbjct:    5 RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALLRRLEAFEHPNVVRLMDV-------------------CATSRTDRDIKVTLVFEHIDQDLRTYLD---KAP-PPGLPVETIKDLMRQFLSGLDFLHANCIVHRDLKPEN-ILVTSNGTVKLADFGLARIYSYQM-ALTPVVVTLWYR 181          

HSP 2 Score: 48.9062 bits (115), Expect = 6.052e-26
Identity = 24/31 (77.42%), Postives = 27/31 (87.10%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APEVLL ST Y+T VDMWSVGCIFAEM +R+
Sbjct:  182 APEVLLQST-YATPVDMWSVGCIFAEMFRRK 211