CF417199

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK12_RAT (Cell division protein kinase 12 OS=Rattus norvegicus GN=Cdk12 PE=1 SV=1)

HSP 1 Score: 115.161 bits (287), Expect = 3.473e-25
Identity = 71/200 (35.50%), Postives = 109/200 (54.50%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLL-QMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAF-TVPLKSYTHEIVTLWYR 599
            ++K++ +  +GEGTYG+VYKAKDK TG+LVALKK RL+ ++EG P TA+RE+ +L Q++ QS+  ++ +  +  D+                     K   YLVFEY+D DL   ++S              I+SF+ QL +G+ +CH    LHRD+K  N               GL R + +   + YT++++TLWYR
Sbjct:  720 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDA---------------LDFKKDKGAFYLVFEYMDHDLMGLLES-----GLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSN-ILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 898          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK12_MOUSE (Cell division protein kinase 12 OS=Mus musculus GN=Cdk12 PE=1 SV=2)

HSP 1 Score: 115.161 bits (287), Expect = 3.473e-25
Identity = 71/200 (35.50%), Postives = 109/200 (54.50%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLL-QMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAF-TVPLKSYTHEIVTLWYR 599
            ++K++ +  +GEGTYG+VYKAKDK TG+LVALKK RL+ ++EG P TA+RE+ +L Q++ QS+  ++ +  +  D+                     K   YLVFEY+D DL   ++S              I+SF+ QL +G+ +CH    LHRD+K  N               GL R + +   + YT++++TLWYR
Sbjct:  720 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQSVVNMKEIVTDKQDA---------------LDFKKDKGAFYLVFEYMDHDLMGLLES-----GLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSN-ILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 898          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: SSN3_GIBMO (Serine/threonine-protein kinase SSN3 OS=Gibberella moniliformis GN=SSN3 PE=1 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 8.379e-25
Identity = 66/208 (31.73%), Postives = 96/208 (46.15%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKA---KDKATGQLVALKKTRLEMDEE-----GIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSY---THEIVTLWYR 599
            ++Y  +  +  GTYG+VYKA     K  G+  A+KK + + + E     GI  +A+RE+SL   L   + V+RL  +   D  +                       ++VFEY + DL + I  H + P   P+PP  I+S ++QL  G  + H + VLHRDLKP N               GL R F  PL S       +VT+WYR
Sbjct:   38 DRYRIIGFISSGTYGRVYKAVGRNGKPVGEF-AIKKFKPDKEGEQISYTGISQSAIREMSLCSELHH-INVIRLCEIVLEDKCI-----------------------FMVFEYAEHDLLQIIHHHTQQPR-HPIPPATIKSIMFQLLNGCQYLHINWVLHRDLKPAN-IMVTSSGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYR 218          

HSP 2 Score: 49.6766 bits (117), Expect = 8.379e-25
Identity = 19/28 (67.86%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE++LGS HY+ A+DMW+VGCIFAE++
Sbjct:  219 APELILGSYHYTPAIDMWAVGCIFAELL 246          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CD11A_HUMAN (Cell division protein kinase 11A OS=Homo sapiens GN=CDK11A PE=1 SV=3)

HSP 1 Score: 113.62 bits (283), Expect = 1.011e-24
Identity = 64/198 (32.32%), Postives = 106/198 (53.54%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            +E+++ L ++ EGTYG VY+AKDK T ++VALK+ ++E ++EG P T+LRE++ +                     LK+ +P+  +       +N    +Y+V  Y++ DLK  +++ +     +P  P  +++ + QL +GV H H + +LHRDLK  N               GL R +  PLK+YT  +VT WYR
Sbjct:  420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTI---------------------LKAQHPNIVTVREIVVGSN-MDKIYIVMNYVEHDLKSLMETMK-----QPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSN-LLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYR 589          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: BUR1_ASPFU (Serine/threonine-protein kinase bur1 OS=Aspergillus fumigatus GN=bur1 PE=3 SV=1)

HSP 1 Score: 90.5077 bits (223), Expect = 1.086e-24
Identity = 63/207 (30.43%), Postives = 101/207 (48.79%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLS-QSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVP-----------LKSYTHEIVTLWYR 599
            +E L K+GEGT+G+VYKA+ K  G +VALKK  +  +++G P TALRE+ LL+MLS +++  ++ + VE                         K ++Y+V  Y++ DL   +++    P      P  I+ ++ QL +G+ + H + +LHRD+K  N               GL R +  P            + YT  +VT WYR
Sbjct:   25 FEFLGKLGEGTFGEVYKARSKKDGSIVALKKILMHNEKDGFPITALREIKLLKMLSHRNILQLKEMAVERSKG-----------------DGRKKPSMYMVTPYMEHDLSGLLEN----PAVNFTEPQ-IKCYMLQLLEGLKYLHGNRILHRDMKAAN-LLISNNGVLQIADFGLARPYDEPPPEPGKGGGEAKRDYTTLVVTRWYR 208          

HSP 2 Score: 43.1282 bits (100), Expect = 1.086e-24
Identity = 17/28 (60.71%), Postives = 21/28 (75.00%), Query Frame = 1

Query:  604 PEVLLGSTHYSTAVDMWSVGCIFAEMVK 687
            PE+LL    Y+TA+DMW VGC+F EM K
Sbjct:  210 PELLLQLRRYTTAIDMWGVGCVFGEMFK 237          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: BUR1_EMENI (Serine/threonine-protein kinase bur1 OS=Emericella nidulans GN=ptkA PE=2 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.087e-24
Identity = 65/211 (30.81%), Postives = 100/211 (47.39%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQ-SLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPR-PLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFT-----------VPLKSYTHEIVTLWYR 599
            + ++E L K+GEGT+G+VYKA+ K  G +VALKK  +  + +G P TALRE+ LL+MLS  ++  +R + VE                         K ++Y+VF Y++ DL   ++      NP        I+ ++ QL +G+ + H + +LHRD+K  N               GL R F               + YT  +VT WYR
Sbjct:   22 IREFEFLGKLGEGTFGEVYKARAKRDGSIVALKKILMHNERDGFPITALREIKLLKMLSHTNIMQLREMAVERSKG-----------------EGRKKPSMYMVFPYMEHDLSGLLE------NPEVHFSEAQIKCYMIQLLEGLKYLHGNCILHRDMKAAN-LLISNQGILQIADFGLARPFDEAPPQPGKGAGEAKRDYTTLVVTRWYR 208          

HSP 2 Score: 41.5874 bits (96), Expect = 1.087e-24
Identity = 16/28 (57.14%), Postives = 21/28 (75.00%), Query Frame = 1

Query:  604 PEVLLGSTHYSTAVDMWSVGCIFAEMVK 687
            PE+LL    Y++A+DMW VGC+F EM K
Sbjct:  210 PELLLQLRRYTSAIDMWGVGCVFGEMFK 237          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: SSN3_PHANO (Serine/threonine-protein kinase SSN3 OS=Phaeosphaeria nodorum GN=SSN3 PE=3 SV=1)

HSP 1 Score: 83.5741 bits (205), Expect = 1.091e-24
Identity = 64/208 (30.77%), Postives = 101/208 (48.56%), Query Frame = 3

Query:    9 EKYEKLEKVGEGTYGKVYKAKDK--ATGQLVALKKTRLEMDEE----GIPPTALREVSLLQMLSQS--LYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSY---THEIVTLWYR 599
            E+Y+ +  +  GTYG+VYKA+ K   TG+  A+KK + + + E    GI  +A+RE++L   L+    ++ V ++  E                            +++VFEY + DL + I  H + P  + +P   I+S LYQL +G+ + H + V+HRDLKP N               GL R F  PL+S       +VT+WYR
Sbjct:   52 ERYKIVGFISSGTYGRVYKAEGKNGRTGEF-AIKKFKPDKEGELQYSGISQSAIREMALCTELAHPNVVHTVEIILEEKC--------------------------IFIVFEYAEHDLLQIIHHHNQ-PQRQAIPARTIKSILYQLLQGLVYLHRNWVMHRDLKPAN-IMVTSAGKVKIGDLGLARLFYKPLQSLFSGDKVVVTIWYR 230          

HSP 2 Score: 50.0618 bits (118), Expect = 1.091e-24
Identity = 20/28 (71.43%), Postives = 26/28 (92.86%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMV 684
            APE+LLGS HY+ AVD+W+VGCIFAE++
Sbjct:  231 APELLLGSRHYTPAVDLWAVGCIFAELL 258          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CRK1_SCHPO (Serine/threonine-protein kinase crk1 OS=Schizosaccharomyces pombe GN=crk1 PE=1 SV=1)

HSP 1 Score: 88.9669 bits (219), Expect = 1.096e-24
Identity = 65/195 (33.33%), Postives = 95/195 (48.72%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYR 599
            Y K  KVGEGTY  V+  + K T + VA+KK ++   ++GI  +ALRE+  L+  S+   V+ L+ V                   F+T    KSNL ++ E+LD+DL+  I             P  I+S++  L +G+ H HS  +LHRDLKP N               GL R F  P    +H+++T WYR
Sbjct:   11 YVKERKVGEGTYAVVFLGRQKETNRRVAIKKIKVGQFKDGIDISALREIKFLRE-SRHDNVIELVDV-------------------FST----KSNLNIILEFLDSDLEMLIKD-----KFIVFQPAHIKSWMVMLLRGLHHIHSRFILHRDLKPNN-LLISSDGVLKLADFGLSRDFGTP-SHMSHQVITRWYR 174          

HSP 2 Score: 44.669 bits (104), Expect = 1.096e-24
Identity = 18/29 (62.07%), Postives = 22/29 (75.86%), Query Frame = 1

Query:  604 PEVLLGSTHYSTAVDMWSVGCIFAEMVKR 690
            PE+ +G   Y T VDMWSVGCIFAE++ R
Sbjct:  176 PELFMGCRSYGTGVDMWSVGCIFAELMLR 204          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK12_HUMAN (Cell division protein kinase 12 OS=Homo sapiens GN=CDK12 PE=1 SV=1)

HSP 1 Score: 113.235 bits (282), Expect = 1.320e-24
Identity = 69/200 (34.50%), Postives = 109/200 (54.50%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLL-QMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAF-TVPLKSYTHEIVTLWYR 599
            ++K++ +  +GEGTYG+VYKA+DK TG+LVALKK RL+ ++EG P TA+RE+ +L Q++ +S+  ++ +  +  D+                     K   YLVFEY+D DL   ++S              I+SF+ QL +G+ +CH    LHRD+K  N               GL R + +   + YT++++TLWYR
Sbjct:  724 VDKFDIIGIIGEGTYGQVYKARDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDA---------------LDFKKDKGAFYLVFEYMDHDLMGLLES-----GLVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSN-ILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: CDK9_CAEEL (Probable cell division protein kinase 9 OS=Caenorhabditis elegans GN=cdk-9 PE=2 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 1.418e-24
Identity = 68/202 (33.66%), Postives = 97/202 (48.02%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPR-PLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTV------PLKSYTHEIVTLWYR 599
            YEKL K+G+GT+G+V+KA+ K TG++VALKK  +E ++EG P TALREV +L+ L     +  L+ V     S KS            T +  ++  YLV      DL   +       NP+  +    I++ +  L  G+   H   +LHRD+K  N               GL R F        P   YT+ +VTLWYR
Sbjct:   85 YEKLNKIGQGTFGEVFKARCKNTGRMVALKKILMENEKEGFPITALREVKMLEQLKHP-NITDLIEV----CSAKSTG---------TTGSKDRATFYLVMALCAHDLAGLLS------NPKIRMSLVHIKTMMKHLMSGLNKLHRSKILHRDMKAAN-VLISKDGILKLADFGLARPFVQRENGAGPRPLYTNRVVTLWYR 265          

HSP 2 Score: 41.9726 bits (97), Expect = 1.418e-24
Identity = 17/30 (56.67%), Postives = 20/30 (66.67%), Query Frame = 1

Query:  604 PEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            PE+LLG   Y T +D+W  GCI AEM  RQ
Sbjct:  267 PELLLGDRQYGTKIDVWGAGCIMAEMWTRQ 296