CF417199

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: GSK3B_HUMAN (Glycogen synthase kinase-3 beta OS=Homo sapiens GN=GSK3B PE=1 SV=2)

HSP 1 Score: 57.7658 bits (138), Expect = 1.561e-14
Identity = 43/159 (27.04%), Postives = 76/159 (47.80%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYL--VFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            Y   + +G G++G VY+AK   +G+LVA+KK   +   +       RE+ +++ L     +VRL                      F +S   K  +YL  V +Y+   + +    + +    + LP   ++ ++YQL + +A+ HS G+ HRD+KPQN
Sbjct:   56 YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKN------RELQIMRKLDHC-NIVRLRYF-------------------FYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAK--QTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQN 186          

HSP 2 Score: 41.5874 bits (96), Expect = 1.561e-14
Identity = 14/31 (45.16%), Postives = 25/31 (80.65%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE++ G+T Y++++D+WS GC+ AE++  Q
Sbjct:  224 APELIFGATDYTSSIDVWSAGCVLAELLLGQ 254          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: JNK1_ANCCA (Stress-activated protein kinase JNK-1 OS=Ancylostoma caninum GN=JNK-1 PE=2 SV=2)

HSP 1 Score: 59.6918 bits (143), Expect = 1.566e-14
Identity = 43/160 (26.88%), Postives = 70/160 (43.75%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +++YE L  +G G  G V  A D  T + VA+KK             A RE  L+ +++           +++   L + +P  +            ++LY+V E +D +L + I           L    +   LYQ+  G+ H HS G++HRDLKP N
Sbjct:   23 LKRYENLRLIGSGAQGIVCAATDMVTNKPVAIKKLSRPFQNVTHAKRAYREFILMNLVNH----------KNIIGLLNAFSPQREVEEF--------NDLYIVMELMDANLCQVIQMD--------LDHERLSYLLYQMLCGIKHLHSAGIIHRDLKPSN 156          

HSP 2 Score: 39.6614 bits (91), Expect = 1.566e-14
Identity = 18/32 (56.25%), Postives = 24/32 (75.00%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQV 696
            APEV+LG   Y   VD+WSVGCIF E+++ +V
Sbjct:  193 APEVILGMG-YGENVDVWSVGCIFGELIRGRV 223          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK14C_DROME (Putative mitogen-activated protein kinase 14C OS=Drosophila melanogaster GN=p38c PE=2 SV=1)

HSP 1 Score: 60.4622 bits (145), Expect = 1.568e-14
Identity = 46/157 (29.30%), Postives = 72/157 (45.86%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            YE +  +G G++G+V K + + T    A+K+     + E       RE+ LL+ ++    V+ LL V H         P   +   F         +YLV   +D DL ++  S R            I+  LYQ+ +G+ + HS GV+HRDLKP N
Sbjct:   20 YEFVRFLGGGSFGQVAKVRLRGTENYFAMKRLMRPFEREEDAKGTYREIRLLKHMNHR-NVISLLNVFH---------PPAHNMMEF-------QQVYLVTHLMDADLHRYSRSKRMSDQE-------IRIILYQILRGLKYIHSAGVVHRDLKPCN 152          

HSP 2 Score: 38.891 bits (89), Expect = 1.568e-14
Identity = 15/32 (46.88%), Postives = 23/32 (71.88%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQV 696
            APE++     Y+ A+D+WSVGCI AE++  +V
Sbjct:  187 APEIIFLRGQYTKAIDVWSVGCILAELITDRV 218          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK13_BOVIN (Mitogen-activated protein kinase 13 OS=Bos taurus GN=MAPK13 PE=2 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 1.617e-14
Identity = 66/205 (32.20%), Postives = 89/205 (43.41%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQNXXXXXXXXXXXXXXXGLGRAFTVPLKSYTHEIVTLWYRGSRG-ASWFH 626
            Y  L  +G G YG V  A DK +G+ VA+KK       E     A RE+ LL+ + Q   V+ LL V    SSL++ +                 + YLV  ++ TDL+K +                IQ  +YQ+ KG+ + HS GV+HRDLKP N               GL R   V +  Y   +VT WYR      SW H
Sbjct:   25 YVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHM-QHENVIGLLDVFTPASSLRNFH-----------------DFYLVMPFMQTDLQKIMGME--------FSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGN-LAVNEDCELKILDFGLARHTDVEMTGY---VVTRWYRAPEVILSWMH 199          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: GSK3A_RAT (Glycogen synthase kinase-3 alpha OS=Rattus norvegicus GN=Gsk3a PE=1 SV=1)

HSP 1 Score: 57.3806 bits (137), Expect = 2.021e-14
Identity = 45/159 (28.30%), Postives = 74/159 (46.54%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYL--VFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            Y  ++ +G G++G VY+A+   T +LVA+KK   +   +       RE+ +++ L     +VRL                      F +S   K  LYL  V EY+   + +      K      +P   ++ ++YQL + +A+ HS GV HRD+KPQN
Sbjct:  119 YTDIKVIGNGSFGVVYQARLAETRELVAIKKVLQDKRFKN------RELQIMRKLDHC-NIVRLRYF-------------------FYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAK--LIIPIIYVKVYMYQLFRSLAYIHSQGVCHRDIKPQN 249          

HSP 2 Score: 41.5874 bits (96), Expect = 2.021e-14
Identity = 14/31 (45.16%), Postives = 25/31 (80.65%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE++ G+T Y++++D+WS GC+ AE++  Q
Sbjct:  287 APELIFGATDYTSSIDVWSAGCVLAELLLGQ 317          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK09_CHICK (Mitogen-activated protein kinase 9 OS=Gallus gallus GN=MAPK9 PE=2 SV=1)

HSP 1 Score: 61.2326 bits (147), Expect = 2.033e-14
Identity = 48/160 (30.00%), Postives = 73/160 (45.62%), Query Frame = 3

Query:    6 MEKYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +++Y++L+ +G G  G V  A D   G  VA+KK       +     A RE+ LL+            CV H +     N  +P        S     ++YLV E +D +L + I  H +  + R      +   LYQ+  G+ H HS G++HRDLKP N
Sbjct:   23 LKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLK------------CVNHKNIISLLNVFTPQK------SLEEFQDVYLVMELMDANLCQVI--HMELDHER------MSYLLYQMLCGIKHLHSAGIIHRDLKPSN 156          

HSP 2 Score: 37.7354 bits (86), Expect = 2.033e-14
Identity = 18/29 (62.07%), Postives = 21/29 (72.41%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVK 687
            APEV+LG   Y   VD+WSVGCI  E+VK
Sbjct:  193 APEVILGMG-YKENVDIWSVGCIMGELVK 220          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: GSK31_SCHPO (Protein kinase gsk31 OS=Schizosaccharomyces pombe GN=gsk31 PE=1 SV=1)

HSP 1 Score: 56.6102 bits (135), Expect = 2.033e-14
Identity = 42/157 (26.75%), Postives = 77/157 (49.04%), Query Frame = 3

Query:   15 YEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            YE    +G G++G V +AK   T   +A+K+   +   +       RE+ +++ +S    +++L+   H      ++NPS D           +++L L+ EY+   +  F D        + +P   I+ + +QL + +A+ HS GV HRD+KPQN
Sbjct:   25 YEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKN------RELQIMRAISHP-NIIKLIAFFH------THNPSKD-----------ETHLCLLLEYMPETV--FDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHSTGVCHRDIKPQN 155          

HSP 2 Score: 42.3578 bits (98), Expect = 2.033e-14
Identity = 14/27 (51.85%), Postives = 22/27 (81.48%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEM 681
            APE++ G+THY+T +D+WS  C+ AE+
Sbjct:  193 APELVFGATHYTTKIDVWSAACVIAEL 219          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK01_HUMAN (Mitogen-activated protein kinase 1 OS=Homo sapiens GN=MAPK1 PE=1 SV=3)

HSP 1 Score: 55.8398 bits (133), Expect = 2.037e-14
Identity = 45/163 (27.61%), Postives = 71/163 (43.56%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVS-LLQMLSQSLY----VVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +Y  L  +GEG YG V  A D      VA+KK     + +      LRE+  LL+   +++     ++R   +E +                         ++Y+V + ++TDL K + +         L    I  FLYQ+ +G+ + HS  VLHRDLKP N
Sbjct:   24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQM------------------------KDVYIVQDLMETDLYKLLKTQH-------LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSN 154          

HSP 2 Score: 43.1282 bits (100), Expect = 2.037e-14
Identity = 20/47 (42.55%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  553 FLSKAIPTRLLLSGIGAPEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            FL++ + TR       APE++L S  Y+ ++D+WSVGCI AEM+  +
Sbjct:  183 FLTEYVATRWYR----APEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MK01_BOVIN (Mitogen-activated protein kinase 1 OS=Bos taurus GN=MAPK1 PE=2 SV=3)

HSP 1 Score: 55.8398 bits (133), Expect = 2.037e-14
Identity = 45/163 (27.61%), Postives = 71/163 (43.56%), Query Frame = 3

Query:   12 KYEKLEKVGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVS-LLQMLSQSLY----VVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHSHGVLHRDLKPQN 485
            +Y  L  +GEG YG V  A D      VA+KK     + +      LRE+  LL+   +++     ++R   +E +                         ++Y+V + ++TDL K + +         L    I  FLYQ+ +G+ + HS  VLHRDLKP N
Sbjct:   24 RYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKIS-PFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQM------------------------KDVYIVQDLMETDLYKLLKTQH-------LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSN 154          

HSP 2 Score: 43.1282 bits (100), Expect = 2.037e-14
Identity = 20/47 (42.55%), Postives = 31/47 (65.96%), Query Frame = 1

Query:  553 FLSKAIPTRLLLSGIGAPEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            FL++ + TR       APE++L S  Y+ ++D+WSVGCI AEM+  +
Sbjct:  183 FLTEYVATRWYR----APEIMLNSKGYTKSIDIWSVGCILAEMLSNR 225          

BLAST of CF417199 vs. ExPASy Swiss-Prot
Match: MSK2_MEDSA (Glycogen synthase kinase-3 homolog MsK-2 OS=Medicago sativa GN=MSK-2 PE=2 SV=1)

HSP 1 Score: 56.9954 bits (136), Expect = 2.636e-14
Identity = 43/152 (28.29%), Postives = 73/152 (48.03%), Query Frame = 3

Query:   33 VGEGTYGKVYKAKDKATGQLVALKKTRLEMDEEGIPPTALREVSLLQMLSQSLYVVRLLCVEHVDSSLKSNNPSPDSASAFATSNNGKSNLYLVFEYLDTDLKKFIDSHRKGPNPRPLPPTLIQSFLYQLCKGVAHCHS-HGVLHRDLKPQN 485
            VG+G++G V++AK   TG+ VA+KK   +   +       RE+  +++L     V    C                    F+T+   +  L LV E++   + + I  H    N R +P   ++ + YQ+C+ +A+ H+  GV HRD+KPQN
Sbjct:   80 VGQGSFGVVFQAKCLETGETVAIKKVLQDKRYKN------RELQTMRLLDHPNVVTLKHCF-------------------FSTTEKDELYLNLVLEFVPETVHRVI-RHYSKMNQR-MPLIYVKLYSYQICRSLAYIHNCVGVSHRDIKPQN 204          

HSP 2 Score: 41.5874 bits (96), Expect = 2.636e-14
Identity = 14/31 (45.16%), Postives = 24/31 (77.42%), Query Frame = 1

Query:  601 APEVLLGSTHYSTAVDMWSVGCIFAEMVKRQ 693
            APE++ G+T Y++A+D+WS GC+  E++  Q
Sbjct:  242 APELIFGATEYTSAIDIWSAGCVLGELLLGQ 272