CF417504

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATJ_RAT (Cathepsin J OS=Rattus norvegicus GN=Ctsj PE=2 SV=2)

HSP 1 Score: 94.7449 bits (234), Expect = 4.154e-20
Identity = 66/194 (34.02%), Postives = 99/194 (51.03%), Query Frame = 1

Query:   94 SDGEQSEDHLLNAEHHFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVHGVTK----FSDLTPSEFRRQFLGLNRRLRLPA-----DAQKAPILPTNDLPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYIL 648
            + G  + D  L+AE  +  +K+K++K+Y+  EE + +  V++ NL+  +     +    +G T     F+D T  EFR+    +     +PA      AQK   +    LP   DWR  G VT V++QG CGSCW+F+A GA+EG  F  TG L  LS Q L+DC            ++GC  G  + AF Y+L
Sbjct:   15 ASGAPARDPNLDAE--WQDWKTKYAKSYSPVEE-ELKRAVWEENLKMIQLHNKENGLGKNGFTMEMNAFADTTGEEFRKSLSDI----LIPAAVTNPSAQKQVSI---GLPNFKDWRKEGYVTPVRNQGKCGSCWAFAAVGAIEGQMFSKTGNLTPLSVQNLLDC-------SKSEGNNGCRWGTAHQAFNYVL 191          

HSP 2 Score: 24.2534 bits (51), Expect = 4.154e-20
Identity = 9/15 (60.00%), Postives = 10/15 (66.67%), Query Frame = 2

Query:  659 GVEREKDYPYTGTDG 703
            G+E E  YPY G DG
Sbjct:  195 GLEAEATYPYEGKDG 209          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: ERVB_TABDI (Ervatamin-B OS=Tabernaemontana divaricata PE=1 SV=1)

HSP 1 Score: 95.9005 bits (237), Expect = 4.205e-20
Identity = 44/85 (51.76%), Postives = 58/85 (68.24%), Query Frame = 1

Query:  394 LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYIL 648
            LP+  DWR  GAV  +K+Q  CGSCW+FSA  A+E  + + TG+L+SLSEQ+LVDCD         +   GCNGG MN+AF+YI+
Sbjct:    1 LPSFVDWRSKGAVNSIKNQKQCGSCWAFSAVAAVESINKIRTGQLISLSEQELVDCD---------TASHGCNGGWMNNAFQYII 76          

HSP 2 Score: 23.0978 bits (48), Expect = 4.205e-20
Identity = 6/16 (37.50%), Postives = 12/16 (75.00%), Query Frame = 2

Query:  656 GGVEREKDYPYTGTDG 703
            GG++ +++YPY+   G
Sbjct:   79 GGIDTQQNYPYSAVQG 94          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CPGP1_ZINOF (Zingipain-1 OS=Zingiber officinale PE=1 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 5.465e-20
Identity = 43/85 (50.59%), Postives = 55/85 (64.71%), Query Frame = 1

Query:  394 LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYIL 648
            LP   DWR+ GAV  VK+QG CGSCW+F A  A+EG + + TG+L+SLSEQQLVDC          + + GC GG    AF+YI+
Sbjct:    3 LPDSIDWREKGAVVPVKNQGGCGSCWAFDAIAAVEGINQIVTGDLISLSEQQLVDC---------STRNHGCEGGWPYRAFQYII 78          

HSP 2 Score: 28.8758 bits (63), Expect = 5.465e-20
Identity = 10/16 (62.50%), Postives = 13/16 (81.25%), Query Frame = 2

Query:  656 GGVEREKDYPYTGTDG 703
            GG+  E+ YPYTGT+G
Sbjct:   81 GGINSEEHYPYTGTNG 96          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATW_HUMAN (Cathepsin W OS=Homo sapiens GN=CTSW PE=1 SV=2)

HSP 1 Score: 97.0561 bits (240), Expect = 7.008e-20
Identity = 64/179 (35.75%), Postives = 94/179 (52.51%), Query Frame = 1

Query:  124 LNAEHHFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLD-PTAVHGVTKFSDLTPSEFRRQFLGLNRRLR-LPADAQKAPIL-PTNDLPTDFDWRD-HGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYIL 648
            L  +  F LF+ +F+++Y + EEH +R  +F  NL +A+R Q  D  TA  GVT FSDLT  EF  Q  G  R    +P+  ++     P   +P   DWR    A++ +KDQ  C  CW+ +A G +E    +S  + V +S Q+L+DC         G C  GC+GG +  AF  +L
Sbjct:   36 LELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDLTEEEFG-QLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVASAISPIKDQKNCNCCWAMAAAGNIETLWRISFWDFVDVSVQELLDC---------GRCGDGCHGGFVWDAFITVL 204          

HSP 2 Score: 21.1718 bits (43), Expect = 7.008e-20
Identity = 7/12 (58.33%), Postives = 9/12 (75.00%), Query Frame = 2

Query:  659 GVEREKDYPYTG 694
            G+  EKDYP+ G
Sbjct:  208 GLASEKDYPFQG 219          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_MOUSE (Cathepsin K OS=Mus musculus GN=Ctsk PE=2 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 5.754e-19
Identity = 61/187 (32.62%), Postives = 94/187 (50.27%), Query Frame = 1

Query:  109 SEDHLLNAEHHFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTND----LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            S + +L+ +  + L+K    K Y ++ +   R  +++ NL++     L     VH     +    D+T  E  ++  GL      P+ +     L T +    +P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E         + GC GG M +AF+Y+
Sbjct:   17 SPEEMLDTQ--WELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIP---PSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE---------NYGCGGGYMTTAFQYV 189          

HSP 2 Score: 23.8682 bits (50), Expect = 5.754e-19
Identity = 8/15 (53.33%), Postives = 10/15 (66.67%), Query Frame = 2

Query:  656 GGVEREKDYPYTGTD 700
            GG++ E  YPY G D
Sbjct:  193 GGIDSEDAYPYVGQD 207          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_BOVIN (Cathepsin K OS=Bos taurus GN=CTSK PE=2 SV=2)

HSP 1 Score: 92.8189 bits (229), Expect = 9.731e-19
Identity = 60/177 (33.90%), Postives = 90/177 (50.85%), Query Frame = 1

Query:  142 FSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAP---ILPTND--LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            + L+K  + K Y ++ +   R  +++ NL+      L     VH     +    D+T  E  ++  GL    ++PA   ++     +P  +   P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E D         GC GG M +AF+Y+
Sbjct:   26 WELWKKTYRKQYNSKGDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGL----KVPASRSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND---------GCGGGYMTNAFQYV 189          

HSP 2 Score: 21.557 bits (44), Expect = 9.731e-19
Identity = 7/14 (50.00%), Postives = 9/14 (64.29%), Query Frame = 2

Query:  659 GVEREKDYPYTGTD 700
            G++ E  YPY G D
Sbjct:  194 GIDSEDAYPYVGQD 207          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_PIG (Cathepsin K OS=Sus scrofa GN=CTSK PE=2 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 1.265e-18
Identity = 60/176 (34.09%), Postives = 87/176 (49.43%), Query Frame = 1

Query:  142 FSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTND----LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            + L+K  + K Y ++ +   R  +++ NL+      L     VH     +    D+T  E  ++  GL      P+ ++    L   D     P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E D         GC GG M +AF+Y+
Sbjct:   27 WELWKKTYRKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVP---PSHSRSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND---------GCGGGYMTNAFQYV 190          

HSP 2 Score: 21.557 bits (44), Expect = 1.265e-18
Identity = 7/14 (50.00%), Postives = 9/14 (64.29%), Query Frame = 2

Query:  659 GVEREKDYPYTGTD 700
            G++ E  YPY G D
Sbjct:  195 GIDSEDAYPYVGQD 208          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_RABIT (Cathepsin K OS=Oryctolagus cuniculus GN=CTSK PE=1 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 1.645e-18
Identity = 60/176 (34.09%), Postives = 87/176 (49.43%), Query Frame = 1

Query:  142 FSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTND----LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            + L+K  +SK Y ++ +   R  +++ NL+      L     VH     +    D+T  E  ++  GL      P+ +     L   D     P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E         + GC GG M +AF+Y+
Sbjct:   26 WELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVP---PSRSHSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE---------NYGCGGGYMTNAFQYV 189          

HSP 2 Score: 21.557 bits (44), Expect = 1.645e-18
Identity = 7/14 (50.00%), Postives = 9/14 (64.29%), Query Frame = 2

Query:  659 GVEREKDYPYTGTD 700
            G++ E  YPY G D
Sbjct:  194 GIDSEDAYPYVGQD 207          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_MACMU (Cathepsin K OS=Macaca mulatta GN=CTSK PE=1 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 1.893e-18
Identity = 61/178 (34.27%), Postives = 90/178 (50.56%), Query Frame = 1

Query:  139 HFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAP---ILPTND--LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            H+ L+K    K Y ++ +   R  +++ NL+      L     VH     +    D+T  E  ++  GL    ++PA   ++     +P  +   P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E D         GC GG M +AF+Y+
Sbjct:   25 HWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTNEEVVQKMTGL----KVPASHSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND---------GCGGGYMTNAFQYV 189          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_MACFA (Cathepsin K OS=Macaca fascicularis GN=CTSK PE=2 SV=1)

HSP 1 Score: 92.8189 bits (229), Expect = 1.893e-18
Identity = 61/178 (34.27%), Postives = 90/178 (50.56%), Query Frame = 1

Query:  139 HFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAP---ILPTND--LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            H+ L+K    K Y ++ +   R  +++ NL+      L     VH     +    D+T  E  ++  GL    ++PA   ++     +P  +   P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E D         GC GG M +AF+Y+
Sbjct:   25 HWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTNEEVVQKMTGL----KVPASHSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND---------GCGGGYMTNAFQYV 189