CF417504

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_CANFA (Cathepsin K OS=Canis familiaris GN=CTSK PE=2 SV=1)

HSP 1 Score: 91.6633 bits (226), Expect = 2.139e-18
Identity = 60/176 (34.09%), Postives = 87/176 (49.43%), Query Frame = 1

Query:  142 FSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTND----LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            + L+K  + K Y ++ +   R  +++ NL+      L     VH     +    D+T  E  ++  GL      P+ ++    L   D     P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E D         GC GG M +AF+Y+
Sbjct:   27 WDLWKKTYRKQYNSKVDELSRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVP---PSHSRSNDTLYIPDWESRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND---------GCGGGYMTNAFQYV 190          

HSP 2 Score: 21.557 bits (44), Expect = 2.139e-18
Identity = 7/14 (50.00%), Postives = 9/14 (64.29%), Query Frame = 2

Query:  659 GVEREKDYPYTGTD 700
            G++ E  YPY G D
Sbjct:  195 GIDSEDAYPYVGQD 208          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_HUMAN (Cathepsin K OS=Homo sapiens GN=CTSK PE=1 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 3.229e-18
Identity = 62/182 (34.07%), Postives = 86/182 (47.25%), Query Frame = 1

Query:  139 HFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGL---------NRRLRLPADAQKAPILPTNDLPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            H+ L+K    K Y  + +   R  +++ NL+      L     VH     +    D+T  E  ++  GL         N  L +P    +AP           D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E D         GC GG M +AF+Y+
Sbjct:   25 HWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAP--------DSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSEND---------GCGGGYMTNAFQYV 189          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATK_RAT (Cathepsin K OS=Rattus norvegicus GN=Ctsk PE=2 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 3.618e-18
Identity = 58/176 (32.95%), Postives = 87/176 (49.43%), Query Frame = 1

Query:  142 FSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVH----GVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTND----LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            + L+K    K Y ++ +   R  +++ NL++     L      H     +    D+T  E  ++  GL      P+ +     L T +    +P   D+R  G VT VK+QG CGSCW+FS+ GALEG     TG+L++LS Q LVDC  E         + GC GG M +AF+Y+
Sbjct:   26 WELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEASLGAHTYELAMNHLGDMTSEEVVQKMTGLRVP---PSRSFSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSE---------NYGCGGGYMTTAFQYV 189          

HSP 2 Score: 23.8682 bits (50), Expect = 3.618e-18
Identity = 8/15 (53.33%), Postives = 10/15 (66.67%), Query Frame = 2

Query:  656 GGVEREKDYPYTGTD 700
            GG++ E  YPY G D
Sbjct:  193 GGIDSEDAYPYVGQD 207          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATW_FELCA (Cathepsin W OS=Felis catus GN=CTSW PE=2 SV=2)

HSP 1 Score: 90.1225 bits (222), Expect = 7.927e-18
Identity = 60/182 (32.97%), Postives = 92/182 (50.55%), Query Frame = 1

Query:  124 LNAEHHFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLD-PTAVHGVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTND-----LPTDFDWRD-HGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYIL 648
            L  +  F+LF+ +++++Y+  EE+  R  +F  NL +A++ +  D  TA  GVT FSDLT  EF R    L    R+  +A K      ++     +P   DWR   G ++ VK Q +C  CW+ +A G +E    +   + V LS Q+L+DC         G C  GC GG +  AF  +L
Sbjct:   36 LELKQAFTLFQIQYNRSYSNPEEYARRLDIFAHNLAQAQQLEEEDLGTAEFGVTPFSDLTEEEFGR----LYGHRRMDGEAPKVGREVGSEEWGESVPPTCDWRKLDGVISSVKKQESCSCCWAMAAAGNIEALWAIKYRQSVELSVQELLDC---------GRCGDGCRGGFVWDAFITVL 204          

HSP 2 Score: 21.1718 bits (43), Expect = 7.927e-18
Identity = 7/12 (58.33%), Postives = 9/12 (75.00%), Query Frame = 2

Query:  659 GVEREKDYPYTG 694
            G+  EKDYP+ G
Sbjct:  208 GLASEKDYPFQG 219          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: ACP1_ENTHI (Cysteine proteinase ACP1 OS=Entamoeba histolytica GN=ACP1 PE=1 SV=2)

HSP 1 Score: 90.1225 bits (222), Expect = 1.227e-17
Identity = 56/168 (33.33%), Postives = 83/168 (49.40%), Query Frame = 1

Query:  142 FSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVHGVTKFSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTNDLPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            F  + +  +K +A + E+ YRF VF  N      ++ ++  A   +  F+D+T  EF +  LG+   +       KA +      P   DWR    +   KDQG CGSCW+F  T  LEG      G+L S SEQQLVDCD         + D+GC GG  +++ ++I
Sbjct:   18 FKQWAATHNKVFANRAEYLYRFAVFLDN------KKFVEANANTELNVFADMTHEEFIQTHLGMTYEVPETTSNVKAAVKAA---PESVDWRS--IMNPAKDQGQCGSCWTFCTTAVLEGRVNKDLGKLYSFSEQQLVDCD---------ASDNGCEGGHPSNSLKFI 165          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: TEST2_MOUSE (Testin-2 OS=Mus musculus PE=2 SV=1)

HSP 1 Score: 89.3521 bits (220), Expect = 1.344e-17
Identity = 62/173 (35.84%), Postives = 83/173 (47.98%), Query Frame = 1

Query:  151 FKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVHGVTK----FSDLTPSEFRRQFLGLNR----RLRLPADAQKAPILPTNDLPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            +++K  K Y   EE   R  V++ N +  +          H  T     F DLT +EF +   G  R    R+ +  D Q   +      P   DWR  G VT VK+QG C S W+FSATG+LEG  F  TG LV LSEQ L+DC          +    C+GG M +AF+Y+
Sbjct:   32 WRTKHGKAYNVNEER-LRRAVWEKNFKMIELHNWEYLEGKHDFTMTMNAFGDLTNTEFVKMMTGFRRQKIKRMHVFQDHQFLYV------PKYVDWRMLGYVTPVKNQGYCASSWAFSATGSLEGQMFKKTGRLVPLSEQNLLDC-------MGSNVTHDCSGGFMQNAFQYV 190          

HSP 2 Score: 21.1718 bits (43), Expect = 1.344e-17
Identity = 7/13 (53.85%), Postives = 9/13 (69.23%), Query Frame = 2

Query:  656 GGVEREKDYPYTG 694
            GG+  E+ YPY G
Sbjct:  194 GGLATEESYPYIG 206          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATL_BRUPA (Cathepsin L-like OS=Brugia pahangi PE=1 SV=1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.740e-17
Identity = 60/205 (29.27%), Postives = 99/205 (48.29%), Query Frame = 1

Query:   61 GDDAMIRQVVPSDGEQSEDHLLNA-EHHFSLFKSKFSKTYATQEEHDYRFRVFKAN------LRRAKRRQLLDPTAVHGVTKFSDLTPSEFR-RQFLGLNRRLRLPADAQKAPIL---PTNDLPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEY 642
            G+  ++++ +    +  E   +   E  +  + +   K Y  Q+E+++R  +F++N      + +   + L+  T    +   +DLT  EF  R  L L  +  L    Q +       +  LP   DWR  GAVT V++QG CGSC++F+   ALE  H   TG L+ LS Q +VDC            ++GC+GG M +AF+Y
Sbjct:   63 GESTVVQEFLKKTEDNGEQRAMEKLETEWKDYVTALGKHY-DQKENNFRMAIFESNELMTERINKKYEQGLVSYTTA--LNDLADLTDEEFMVRNGLRLPNQTDLRGKRQTSEFYRYDKSERLPDQVDWRTKGAVTPVRNQGECGSCYAFATAAALEAYHKQMTGRLLDLSPQNIVDCTRNLG-------NNGCSGGYMPTAFQY 257          

HSP 2 Score: 22.3274 bits (46), Expect = 1.740e-17
Identity = 8/19 (42.11%), Postives = 11/19 (57.89%), Query Frame = 2

Query:  644 YSRLGGVEREKDYPYTGTD 700
            Y+   G+  E  YPY GT+
Sbjct:  257 YASRYGIAMESRYPYVGTE 275          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: TEST2_RAT (Testin-2 OS=Rattus norvegicus GN=Testin PE=1 SV=2)

HSP 1 Score: 88.5817 bits (218), Expect = 2.271e-17
Identity = 61/172 (35.47%), Postives = 82/172 (47.67%), Query Frame = 1

Query:  151 FKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVHGVTK----FSDLTPSEFRRQFLGLNRRLRLPADAQKAPILPTND---LPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            +++K  KTY   EE   R  V++ N +  +          H  T     F DLT  EF +   G  R+       +K  I   +    +P   DWR  G VT VK+QG C S W+FSATG+LEG  F  T  L+ LSEQ L+DC          +   GC+GG M  AF+Y+
Sbjct:   32 WRTKHGKTYNMNEERLKR-AVWEKNFKMIELHNWEYLEGRHDFTMAMNAFGDLTNIEFVKMMTGFQRQ-----KIKKTHIFQDHQFLYVPKRVDWRQLGYVTPVKNQGHCASSWAFSATGSLEGQMFRKTERLIPLSEQNLLDC-------MGSNVTHGCSGGFMQYAFQYV 190          

HSP 2 Score: 21.1718 bits (43), Expect = 2.271e-17
Identity = 7/13 (53.85%), Postives = 9/13 (69.23%), Query Frame = 2

Query:  656 GGVEREKDYPYTG 694
            GG+  E+ YPY G
Sbjct:  194 GGLATEESYPYRG 206          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: MEX2_JACME (Chymomexicain OS=Jacaratia mexicana PE=1 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 2.302e-17
Identity = 38/83 (45.78%), Postives = 50/83 (60.24%), Query Frame = 1

Query:  397 PTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYI 645
            P   DWRD GAVT VK+Q  CGSCW+FS    +EG + + TG+L+SLSEQ+L+DCD             GC GG    + +Y+
Sbjct:    2 PESIDWRDKGAVTPVKNQNPCGSCWAFSTVATVEGINKIRTGKLISLSEQELLDCDRR---------SHGCKGGYQTGSIQYV 75          

HSP 2 Score: 23.8682 bits (50), Expect = 2.302e-17
Identity = 9/16 (56.25%), Postives = 10/16 (62.50%), Query Frame = 2

Query:  656 GGVEREKDYPYTGTDG 703
            GGV  EK+YPY    G
Sbjct:   79 GGVHTEKEYPYEKKQG 94          

BLAST of CF417504 vs. ExPASy Swiss-Prot
Match: CATR_MOUSE (Cathepsin R OS=Mus musculus GN=Ctsr PE=2 SV=1)

HSP 1 Score: 82.8037 bits (203), Expect = 2.953e-17
Identity = 61/186 (32.80%), Postives = 92/186 (49.46%), Query Frame = 1

Query:  115 DHLLNAEHHFSLFKSKFSKTYATQEEHDYRFRVFKANLRRAKRRQLLDPTAVHGVT----KFSDLTPSEFRRQFLGLN----RRLRLPADAQKAPILPTNDLPTDFDWRDHGAVTGVKDQGACGSCWSFSATGALEGAHFLSTGELVSLSEQQLVDCDHECDPEESGSCDSGCNGGLMNSAFEYIL 648
            D  L+AE  +  +K K++K+Y+ +EE   R  V++  L+  K     +    +G T    +F D T  EFR+  + ++    R  +     +   ILP        DWR  G VT V+ QG C +CW+F+ TGA+E      TG+L  LS Q LVDC            ++GC GG   +AF+Y+L
Sbjct:   22 DSSLDAE--WQDWKIKYNKSYSLKEEKLKRV-VWEEKLKMIKLHNRENSLGKNGFTMKMNEFGDQTDEEFRKMMIEISVWTHREGKSIMKREAGSILPKF-----VDWRKKGYVTPVRRQGDCDACWAFAVTGAIEAQAIWQTGKLTPLSVQNLVDC-------SKPQGNNGCLGGDTYNAFQYVL 192          

HSP 2 Score: 26.5646 bits (57), Expect = 2.953e-17
Identity = 10/16 (62.50%), Postives = 11/16 (68.75%), Query Frame = 2

Query:  656 GGVEREKDYPYTGTDG 703
            GG+E E  YPY G DG
Sbjct:  195 GGLESEATYPYEGKDG 210