CF417835

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: MBK2_CAEBR (Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2 OS=Caenorhabditis briggsae GN=mbk-2 PE=3 SV=2)

HSP 1 Score: 163.31 bits (412), Expect = 9.086e-40
Identity = 84/192 (43.75%), Postives = 116/192 (60.42%), Query Frame = 2

Query:   29 VCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            V +K+++N K F  Q+ +EI++L ++ + D    ++++ + DYF +R H  I  ELL  NLYE  K N+  G    F++  ++      L  L  L    LIHCDLKPEN+L+K   R  +KVID GSSCF+   + +Y+QSR YRAPEVILG  Y   ID+WSLGCILAEL TG  L   +     LA +I
Sbjct:  486 VALKLVRNEKRFHRQADEEIRILDHLRRQDSDGTHNIIHMLDYFNFRNHKCITFELLSINLYELIKRNKFQG----FSLMLVRKFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQGRSGIKVIDFGSSCFDDQRIYTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDENDQLALII 673          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYR1B_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Mus musculus GN=Dyrk1b PE=1 SV=3)

HSP 1 Score: 159.844 bits (403), Expect = 1.005e-38
Identity = 87/203 (42.86%), Postives = 122/203 (60.10%), Query Frame = 2

Query:    2 AHDLHTGMDVCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            A+D  T   V +KIIKN K F +Q+  E++LL+ +N+HD   KY+++ L  +F +R HL +V ELL  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG  YD  ID+WSLGCIL E+ TG  LF   +    ++R++
Sbjct:  128 AYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQ----QLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIV 326          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYRK1_DICDI (Probable serine/threonine-protein kinase dyrk1 OS=Dictyostelium discoideum GN=dyrk1 PE=3 SV=1)

HSP 1 Score: 159.458 bits (402), Expect = 1.312e-38
Identity = 82/194 (42.27%), Postives = 120/194 (61.86%), Query Frame = 2

Query:   29 VCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            V +KIIKN   F++Q+L EI+LL+ +N  DP D+Y +++L  +F +R HL IV ELL  NLY+  +     G     ++  ++    Q L AL F+    + +IHCDLKPENIL+++  R  +K+ID GSSC   + +  Y+QSR YR+PE++L L Y   ID+WSLGCIL E+  G  LF   +    L ++I
Sbjct:  330 VAIKIIKNKVPFYNQALIEIRLLELMNNKDPEDQYKIIKLKHHFKFRNHLCIVTELLSYNLYDLLRNTHFHG----VSLNLIKKFAHQILTALFFMSTPEVDVIHCDLKPENILLRNPKRSAIKIIDFGSSCHSNERMYKYIQSRFYRSPEILLELEYSFSIDMWSLGCILVEMHVGEPLFSGQNEQDQLTKII 519          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYR1B_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1B OS=Homo sapiens GN=DYRK1B PE=1 SV=1)

HSP 1 Score: 158.688 bits (400), Expect = 2.238e-38
Identity = 87/203 (42.86%), Postives = 121/203 (59.61%), Query Frame = 2

Query:    2 AHDLHTGMDVCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            A+D  T   V +KIIKN K F +Q+  E++LL+ +N+HD   KY+++ L  +F +R HL +V ELL  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG  YD  ID+WSLGCIL E+ TG  LF   +    + R++
Sbjct:  128 AYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQ----QLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIV 326          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYR1A_XENTR (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Xenopus tropicalis GN=dyrk1a PE=2 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 4.986e-38
Identity = 83/194 (42.78%), Postives = 119/194 (61.34%), Query Frame = 2

Query:   29 VCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            V +KIIKN K F +Q+  E++LL+ +NKHD   KY+++ L  +F +R HL +V E+L  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG+ YD  ID+WSLGCIL E+ TG  LF   +    +++++
Sbjct:  177 VAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQ----QMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMSKIV 366          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: MNB_DROME (Serine/threonine-protein kinase minibrain OS=Drosophila melanogaster GN=mnb PE=1 SV=2)

HSP 1 Score: 157.147 bits (396), Expect = 6.512e-38
Identity = 85/203 (41.87%), Postives = 122/203 (60.10%), Query Frame = 2

Query:    2 AHDLHTGMDVCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            A+D      V +KIIKN K F +Q+  E+KLL+ +N+ D  +KY++++L  +F +R HL +V ELL  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG+ YD  ID+WSLGCIL E+ TG  LF   +    + +++
Sbjct:  181 AYDHEEQCHVAIKIIKNKKPFLNQAQIEVKLLEMMNRADAENKYYIVKLKRHFMWRNHLCLVFELLSYNLYDLLRNTNFRGVSLNLTRKFAQ----QLCTALLFLSTPELNIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYHYIQSRFYRSPEVLLGIQYDLAIDMWSLGCILVEMHTGEPLFSGCNEVDQMNKIV 379          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYR1A_XENLA (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Xenopus laevis GN=dyrk1a PE=2 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 1.111e-37
Identity = 83/194 (42.78%), Postives = 118/194 (60.82%), Query Frame = 2

Query:   29 VCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            V +KIIKN K F +Q+  E++LL+ +NKHD   KY+++ L  +F +R HL +V E+L  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG  YD  ID+WSLGCIL E+ TG  LF   +    +++++
Sbjct:  177 VAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQ----QMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMSKIV 366          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYR1A_RAT (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Rattus norvegicus GN=Dyrk1a PE=1 SV=2)

HSP 1 Score: 156.377 bits (394), Expect = 1.111e-37
Identity = 83/194 (42.78%), Postives = 118/194 (60.82%), Query Frame = 2

Query:   29 VCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            V +KIIKN K F +Q+  E++LL+ +NKHD   KY+++ L  +F +R HL +V E+L  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG+ YD  ID+WSLGCIL E+ TG  LF   +    + +++
Sbjct:  185 VAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQ----QMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIV 374          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYR1A_MOUSE (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Mus musculus GN=Dyrk1a PE=1 SV=1)

HSP 1 Score: 156.377 bits (394), Expect = 1.111e-37
Identity = 83/194 (42.78%), Postives = 118/194 (60.82%), Query Frame = 2

Query:   29 VCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            V +KIIKN K F +Q+  E++LL+ +NKHD   KY+++ L  +F +R HL +V E+L  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG+ YD  ID+WSLGCIL E+ TG  LF   +    + +++
Sbjct:  185 VAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQ----QMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIV 374          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: DYR1A_HUMAN (Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens GN=DYRK1A PE=1 SV=2)

HSP 1 Score: 156.377 bits (394), Expect = 1.111e-37
Identity = 83/194 (42.78%), Postives = 118/194 (60.82%), Query Frame = 2

Query:   29 VCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG--LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            V +KIIKN K F +Q+  E++LL+ +NKHD   KY+++ L  +F +R HL +V E+L  NLY+  +     G  +  T    Q    Q   AL FL    L +IHCDLKPENIL+ +  R  +K++D GSSC     +  Y+QSR YR+PEV+LG+ YD  ID+WSLGCIL E+ TG  LF   +    + +++
Sbjct:  185 VAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQ----QMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIV 374