CF417835

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: UNC51_CAEEL (Serine/threonine-protein kinase unc-51 OS=Caenorhabditis elegans GN=unc-51 PE=1 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 42/118 (35.59%), Postives = 64/118 (54.24%), Query Frame = 2

Query:  272 LQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCE--------VKVIDLGSSCFETDHL--CSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLA 595
            +Q   +Q   AL+ ++  G++H DLKP+NIL+ + SR +        +K+ D G + F  D +   +   S  Y APEVI+ + YD K D+WS+G IL +  TG   F   +P  L A
Sbjct:  111 IQHFVVQIAHALEAINKKGIVHRDLKPQNILLCNNSRTQNPHFTDIVIKLADFGFARFLNDGVMAATLCGSPMYMAPEVIMSMQYDAKADLWSIGTILFQCLTGKAPFVAQTPPQLKA 228          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: NLK_CAEBR (Serine/threonine kinase NLK OS=Caenorhabditis briggsae GN=lit-1 PE=3 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 42/120 (35.00%), Postives = 66/120 (55.00%), Query Frame = 2

Query:  260 TMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSS----CFETDHLCSYVQSRSYRAPEVILGLS-YDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            T+  ++    Q L  L++LH   ++H D+KP N+LV S   C +K+ D G +      +  ++   V ++ YRAPE+++G   Y   +DIWS+GCI AEL    +LFQ   P   L  +I
Sbjct:  364 TIDHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNS--NCILKICDFGLARTWDSRDRLNMTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMII 481          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: NEK10_HUMAN (Serine/threonine-protein kinase Nek10 OS=Homo sapiens GN=NEK10 PE=2 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 50/161 (31.06%), Postives = 79/161 (49.07%), Query Frame = 2

Query:  131 YH--LLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHG-LGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            YH  ++R Y  F   + L IV EL++      H F+       +FT  RL  I IQ   AL++LH    ++H DL P NI++    +  V    L     E   L S V +  Y  PEV+    Y +K D+W++GCIL ++ T +  F + +  +L  +++
Sbjct:  583 YHPNIVRYYKTFLENDRLYIVMELIEGAPLGEH-FSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVADFGLAKQKQENSKLTSVVGTILYSCPEVLKSEPYGEKADVWAVGCILYQMATLSPPFYSTNMLSLATKIV 742          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: IPL1_KLULA (Spindle assembly checkpoint kinase OS=Kluyveromyces lactis GN=IPL1 PE=3 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 48/163 (29.45%), Postives = 82/163 (50.31%), Query Frame = 2

Query:  134 HLLRLYDYFYYREHLLIVCELLK-ANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDH-----LCSYVQSRSYRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARVI 604
            +L +LY +FY  + + ++ E +    LY+F K N    G +  T+        Q   AL ++H   ++H D+KPENIL+   +   +K+ D G S +  D      LC  +    Y +PE+I    Y+ K+D+W+LG +  EL  G+  F+ D+      R++
Sbjct:  159 NLTQLYGFFYDEKRVYLLMEYVYYGELYKFLKNN----GPLNETLASY--FVYQMANALDYMHSKNILHRDIKPENILIGFNNT--IKLTDFGWSVYNEDGQKRKTLCGTID---YLSPELIKSREYNNKVDVWALGVLTYELLVGSPPFEEDTKEMTYRRIL 310          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: CTK1_SCHPO (CTD kinase subunit alpha OS=Schizosaccharomyces pombe GN=lsk1 PE=1 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 41/112 (36.61%), Postives = 65/112 (58.04%), Query Frame = 2

Query:  248 EVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSYVQSRS----YRAPEVILG-LSYDKKIDIWSLGCILAELCTGNVLFQ 568
            +++FT   ++ ++ Q  EAL +LH  G++H D+K  NIL+ +    ++K  D G + F T    +   +R     +R PE++LG  +YD  +DIWS GCI+ EL TG   FQ
Sbjct:  368 QLHFTPGNIKHLSKQIFEALAYLHHRGVLHRDIKGSNILLNNNG--DLKFADFGLARFNTSSKSANYTNRVITLWFRPPELLLGETAYDTAVDIWSAGCIVMELFTGKPFFQ 477          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: CDK7_MOUSE (Cell division protein kinase 7 OS=Mus musculus GN=Cdk7 PE=1 SV=2)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 58/208 (27.88%), Postives = 103/208 (49.52%), Query Frame = 2

Query:    2 AHDLHTGMDVCVKIIK-----NNKDFFDQS-LDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSY-VQSRSYRAPEVILGL-SYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARV 601
            A D +T   V +K IK       KD  +++ L EIKLL+ ++  +      ++ L D F ++ ++ +V + ++ +L    K N      +  T   +++  +  L+ L++LH   ++H DLKP N+L+      ++    L  S    +   ++ V +R YRAPE++ G   Y   +D+W++GCILAEL         DS    L R+
Sbjct:   29 ARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDN-----SLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRI 225          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: CDK7_HUMAN (Cell division protein kinase 7 OS=Homo sapiens GN=CDK7 PE=1 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 58/208 (27.88%), Postives = 103/208 (49.52%), Query Frame = 2

Query:    2 AHDLHTGMDVCVKIIK-----NNKDFFDQS-LDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFETDHLCSY-VQSRSYRAPEVILGL-SYDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARV 601
            A D +T   V +K IK       KD  +++ L EIKLL+ ++  +      ++ L D F ++ ++ +V + ++ +L    K N      +  T   +++  +  L+ L++LH   ++H DLKP N+L+      ++    L  S    +   ++ V +R YRAPE++ G   Y   +D+W++GCILAEL         DS    L R+
Sbjct:   29 ARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPN------IIGLLDAFGHKSNISLVFDFMETDLEVIIKDN-----SLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRI 225          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: CDC2H_PLAYO (Cell division control protein 2 homolog OS=Plasmodium yoelii yoelii GN=CRK2 PE=3 SV=1)

HSP 1 Score: 73.1738 bits (178), Expect = 1.237e-12
Identity = 55/180 (30.56%), Postives = 91/180 (50.56%), Query Frame = 2

Query:   74 SLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSC---FETDHLCSYVQSRSYRAPEVILGLS-YDKKIDIWSLGCILAELCTGNVLFQNDSPATLLARV 601
            S+ EI +LK + +H      ++++LYD  + ++ L++V E L  +L +    +   GG    T    +S  +Q L  + + H   ++H DLKP+N+L+      E+K+ D G +             V +  YRAP++++G   Y   IDIWS+GCI AE+  G  LF   S    L R+
Sbjct:   48 SIREISILKEL-RHS-----NIVKLYDVIHAKKRLILVFEHLDQDLKKL--IDVCDGGLESVTA---KSFLLQLLNGIAYCHEHRVLHRDLKPQNLLINREG--ELKIADFGLARAFGIPARRYTHEVVTLWYRAPDILMGSKKYSTPIDIWSVGCIFAEMVNGRPLFPGVSETDQLMRI 214          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: Y0700_DICDI (Probable serine/threonine-protein kinase DDB_G0286841 OS=Dictyostelium discoideum GN=DDB_G0286841 PE=3 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 1.615e-12
Identity = 61/214 (28.50%), Postives = 91/214 (42.52%), Query Frame = 2

Query:   17 TGMDVCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKAN--LYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSCFE-TDHLCSYVQSRS-----------------------YRAPEVILGLSYDKKIDIWSLGCILAELCTGNVLFQNDSP 580
            T   V +K+IK +       +D++ + K +  +   +   ++ L+  F   + L  V E L           FN     ++       ++I  Q +  L++LH  G+IH DLKP+NIL+ S     +K+ D G S F+  D  C+    ++                       Y  PEVILG  Y K ID WSLG IL E   G   FQ D P
Sbjct:   86 TKKTVAIKVIKKSDTIKKMMVDQVNIEKTILSNYKCN--FIVELFSSFQTDKKLFFVMEFLNGGDCASLLRSFNNNMPEDL------TKNIIAQIIICLEYLHNHGIIHRDLKPDNILIDSNGH--IKLADFGLSKFDFVDESCNIKILKNSFTLYNTNNNNTTENQKILGTPYYIPPEVILGKGYGKTIDWWSLGIILYEFLIGYPPFQEDEP 289          

BLAST of CF417835 vs. ExPASy Swiss-Prot
Match: SMKZ_MOUSE (Sperm motility kinase Z OS=Mus musculus PE=2 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 1.615e-12
Identity = 50/185 (27.03%), Postives = 96/185 (51.89%), Query Frame = 2

Query:   17 TGMDVCVKIIKNNKDFFDQSLDEIKLLKYVNKHDPGDKYHLLRLYDYFYYREHLLIVCELLKANLYEFHKFNRESGGEVYFTMPRLQSITIQCLEALQFLHGLGLIHCDLKPENILVKSYSRCEVKVIDLGSSC-----FETDHLCSYVQSRSYRAPEVILGLSYD-KKIDIWSLGCILAELCTG 553
            TG+ V VK +K  + +++  + E++++K ++  +      ++ L       +++ ++ E+ +    + H   +E+           +SI +Q L A+ + HG G++H DLKP+N++V  +    VK++D G         + + LC   Q   +  PE+ LGL YD  K+DIW+LG +L  + TG
Sbjct:   50 TGVTVAVKALKYQR-WWEPKVSEVEIMKMLSHPN------IVSLLQVIETEQNIYLIMEVAQGT--QLHNRVQEAR---CLKEDEARSIFVQLLSAIGYCHGEGVVHRDLKPDNVIVDEHG--NVKIVDFGLGARFMPGQKLERLCGAFQ---FIPPEIFLGLPYDGPKVDIWALGVLLYYMVTG 217