CF503945

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: Y9871_DICDI (Probable serine/threonine-protein kinase DDB_G0271682 OS=Dictyostelium discoideum GN=DDB_G0271682 PE=3 SV=2)

HSP 1 Score: 103.605 bits (257), Expect = 8.455e-22
Identity = 61/143 (42.66%), Postives = 80/143 (55.94%), Query Frame = 1

Query:  196 DDVAECEIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPN-NQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            +D  +  I   E+   ++IG G+ GEV + +W GT VAVK         +  EEF  EV I+K +RHPNVVLFMG      NL+I+TE+L RGSL  +L   N ++               GMNYLH  +P I+HRDLKS NL
Sbjct:  348 EDSLKLNIQENELLFIKKIGSGACGEVCQYEWKGTPVAVKTIFKSLLRKDKKEEFEKEVSILKCLRHPNVVLFMGTCLLNGNLAIITEYLNRGSLRDVLTTMNKSELSLSVKVKMLIDVAQGMNYLHTYSPPIIHRDLKSLNL 490          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: KSR1_MOUSE (Kinase suppressor of Ras 1 OS=Mus musculus GN=Ksr1 PE=1 SV=1)

HSP 1 Score: 100.523 bits (249), Expect = 7.157e-21
Identity = 58/139 (41.73%), Postives = 80/139 (57.55%), Query Frame = 1

Query:  208 ECEIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGES-LEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            E +IP+E++ LGE IG G +G V+RG WHG EVA+ R L+ D   +  L+ F+ EV+  ++ RH NVVLFMGA   PP+L+I+T F    +L+  +  P                  GM YLH     IVH+DLKS N+
Sbjct:  555 EWDIPFEQVELGEPIGQGRWGRVHRGRWHG-EVAI-RLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLH--AKGIVHKDLKSKNV 689          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: KSR1_HUMAN (Kinase suppressor of Ras 1 OS=Homo sapiens GN=KSR1 PE=1 SV=2)

HSP 1 Score: 100.523 bits (249), Expect = 7.157e-21
Identity = 58/139 (41.73%), Postives = 80/139 (57.55%), Query Frame = 1

Query:  208 ECEIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGES-LEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            E +IP+E++ LGE IG G +G V+RG WHG EVA+ R L+ D   +  L+ F+ EV+  ++ RH NVVLFMGA   PP+L+I+T F    +L+  +  P                  GM YLH     IVH+DLKS N+
Sbjct:  603 EWDIPFEQVELGEPIGQGRWGRVHRGRWHG-EVAI-RLLEMDGHNQDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLH--AKGIVHKDLKSKNV 737          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: PATS1_DICDI (Probable serine/threonine-protein kinase pats1 OS=Dictyostelium discoideum GN=pats1 PE=3 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 1.221e-20
Identity = 54/147 (36.73%), Postives = 76/147 (51.70%), Query Frame = 1

Query:  214 EIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRF-----------LDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            +IP++++ + E IG G    VYR  W G  VAVK+            ++     ++  EFR E  +M  + HPN+V   G    P  L IVTE+LP G+LY  LH+P  +               GM +LH+ TP I+HRDLKSPN+
Sbjct: 2241 KIPFDQLMIEELIGEGGAALVYRARWQGQTVAVKKLKTIENLDSPIEINDISLSKAFNEFRRECWVMSELEHPNIVQLKGLCLDP--LCIVTEYLPHGNLYSFLHKPEMEFSWLFRLKVALDISSGMAFLHSSTPPIIHRDLKSPNI 2385          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: RMIL_AVII1 (Serine/threonine-protein kinase-transforming protein Rmil OS=Avian retrovirus IC10 GN=V-RMIL PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 1.595e-20
Identity = 58/142 (40.85%), Postives = 83/142 (58.45%), Query Frame = 1

Query:  196 DDVAECEIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            D   + EIP  +IT+G+RIG GS+G VY+G WHG +VAVK         + L+ F++EV ++++ RH N++LFMG  T+ P L+IVT++    SLY  LH    +               GM+YLH     I+HRDLKS N+
Sbjct:   55 DSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH--AKSIIHRDLKSNNI 192          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: RMIL_AVEVR (Serine/threonine-protein kinase-transforming protein Rmil OS=Avian rous-associated virus type 1 GN=V-RMIL PE=3 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 1.595e-20
Identity = 58/142 (40.85%), Postives = 83/142 (58.45%), Query Frame = 1

Query:  196 DDVAECEIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            D   + EIP  +IT+G+RIG GS+G VY+G WHG +VAVK         + L+ F++EV ++++ RH N++LFMG  T+ P L+IVT++    SLY  LH    +               GM+YLH     I+HRDLKS N+
Sbjct:   71 DSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH--AKSIIHRDLKSNNI 208          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: RAF1_RAT (RAF proto-oncogene serine/threonine-protein kinase OS=Rattus norvegicus GN=Raf1 PE=1 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 1.595e-20
Identity = 57/136 (41.91%), Postives = 80/136 (58.82%), Query Frame = 1

Query:  214 EIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            EI   E+ L  RIG GS+G VY+G WHG +VAVK     D   E L+ FR+EV ++++ RH N++LFMG +T+  NL+IVT++    SLY+ LH    +               GM+YLH     I+HRD+KS N+
Sbjct:  343 EIEASEVMLSTRIGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH--AKNIIHRDMKSNNI 474          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: RAF1_MOUSE (RAF proto-oncogene serine/threonine-protein kinase OS=Mus musculus GN=Raf1 PE=1 SV=2)

HSP 1 Score: 99.3673 bits (246), Expect = 1.595e-20
Identity = 57/136 (41.91%), Postives = 80/136 (58.82%), Query Frame = 1

Query:  214 EIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            EI   E+ L  RIG GS+G VY+G WHG +VAVK     D   E L+ FR+EV ++++ RH N++LFMG +T+  NL+IVT++    SLY+ LH    +               GM+YLH     I+HRD+KS N+
Sbjct:  343 EIEASEVMLSTRIGSGSFGTVYKGKWHG-DVAVKILKVVDPTPEQLQAFRNEVAVLRKTRHVNILLFMGYMTK-DNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH--AKNIIHRDMKSNNI 474          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: BRAF1_MOUSE (B-Raf proto-oncogene serine/threonine-protein kinase OS=Mus musculus GN=Braf PE=1 SV=2)

HSP 1 Score: 99.3673 bits (246), Expect = 1.595e-20
Identity = 58/142 (40.85%), Postives = 83/142 (58.45%), Query Frame = 1

Query:  196 DDVAECEIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            D   + EIP  +IT+G+RIG GS+G VY+G WHG +VAVK         + L+ F++EV ++++ RH N++LFMG  T+ P L+IVT++    SLY  LH    +               GM+YLH     I+HRDLKS N+
Sbjct:  482 DSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH--AKSIIHRDLKSNNI 619          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: BRAF1_HUMAN (B-Raf proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=BRAF PE=1 SV=4)

HSP 1 Score: 99.3673 bits (246), Expect = 1.595e-20
Identity = 58/142 (40.85%), Postives = 83/142 (58.45%), Query Frame = 1

Query:  196 DDVAECEIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            D   + EIP  +IT+G+RIG GS+G VY+G WHG +VAVK         + L+ F++EV ++++ RH N++LFMG  T+ P L+IVT++    SLY  LH    +               GM+YLH     I+HRDLKS N+
Sbjct:  445 DSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHG-DVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTK-PQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLH--AKSIIHRDLKSNNI 582