CF503945

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: PYK2_DICDI (Dual specificity protein kinase pyk2 OS=Dictyostelium discoideum GN=splB PE=2 SV=2)

HSP 1 Score: 75.8702 bits (185), Expect = 1.888e-13
Identity = 46/136 (33.82%), Postives = 72/136 (52.94%), Query Frame = 1

Query:  229 EITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNN-----QXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            +I   +++G G++ EV+ G W G  VA+K+        +  E F  EV  +K+  H N+V+F+GA  +P    I+TE++  GSLY +LH PN+     +               G+ +LH+ T  IVHRDL S N+
Sbjct:  852 DIQFIQKVGEGAFSEVWEGWWKGIHVAIKKLKIIGDEEQFKERFIREVQNLKKGNHQNIVMFIGACYKPA--CIITEYMAGGSLYNILHNPNSSTPKVKYSFPLVLKMATDMALGLLHLHSIT--IVHRDLTSQNI 983          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: Y9849_DICDI (Probable serine/threonine-protein kinase DDB_G0278535 OS=Dictyostelium discoideum GN=DDB_G0278535 PE=3 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 2.466e-13
Identity = 51/135 (37.78%), Postives = 66/135 (48.89%), Query Frame = 1

Query:  217 IPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            I   E+    ++G GS G+VY+G + G EVAVK  L        LEEF+ E  IM  +R   +V F GA   P  L +V E+  R SLY +++                    G+  LHN TP IVHRD KS NL
Sbjct:  524 IDHSELEYTLKLGSGSSGKVYKGLYKGKEVAVK-VLKSITTQSQLEEFKKEFQIMGSIRSQFMVTFYGACIEP-KLCMVMEYCSRDSLYHVMNTKKYDIGWDRFFQFTMQMTLGVQCLHNWTPQIVHRDFKSLNL 656          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: MLTK_MOUSE (Mitogen-activated protein kinase kinase kinase MLT OS=Mus musculus GN=Mltk PE=1 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 2.466e-13
Identity = 47/140 (33.57%), Postives = 69/140 (49.29%), Query Frame = 1

Query:  214 EIPWEEITLGERIGLGSYGEVYRGDW--HGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLH-RPNNQXXXXXXXXXXXXXXXGMNYLHNCTPV-IVHRDLKSPNL 621
            +I ++++   E  G GS+G VYR  W     EVAVK+ L          +   E  I+  + H N++ F G +  PPN  IVTE+   GSLY  ++   + +               GM+YLH   PV ++HRDLKS N+
Sbjct:   10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLL----------KIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMEHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNV 139          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: MLTK_HUMAN (Mitogen-activated protein kinase kinase kinase MLT OS=Homo sapiens GN=MLTK PE=1 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 2.466e-13
Identity = 47/140 (33.57%), Postives = 69/140 (49.29%), Query Frame = 1

Query:  214 EIPWEEITLGERIGLGSYGEVYRGDW--HGTEVAVKRFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLH-RPNNQXXXXXXXXXXXXXXXGMNYLHNCTPV-IVHRDLKSPNL 621
            +I ++++   E  G GS+G VYR  W     EVAVK+ L          +   E  I+  + H N++ F G +  PPN  IVTE+   GSLY  ++   + +               GM+YLH   PV ++HRDLKS N+
Sbjct:   10 QIKFDDLQFFENCGGGSFGSVYRAKWISQDKEVAVKKLL----------KIEKEAEILSVLSHRNIIQFYGVILEPPNYGIVTEYASLGSLYDYINSNRSEEMDMDHIMTWATDVAKGMHYLHMEAPVKVIHRDLKSRNV 139          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: M3KL4_MOUSE (Mitogen-activated protein kinase kinase kinase OS=Mus musculus GN=Mlk4 PE=2 SV=2)

HSP 1 Score: 75.485 bits (184), Expect = 2.466e-13
Identity = 53/150 (35.33%), Postives = 70/150 (46.67%), Query Frame = 1

Query:  217 IPWEEITLGERIGLGSYGEVYRGDWHGTEVAVK---RFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLL-----------HRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPV-IVHRDLKSPNL 621
            + +E + L E IG G +G+VYR  W G EVAVK   R  +QD    + E  R E  +   +RHPN++   G   R P+L +V EF   G+L R L            R   +               GM YLH    V I+HRDLKS N+
Sbjct:  105 VDFERLELKELIGAGGFGQVYRATWQGQEVAVKAARRDPEQD-AAAAAESVRREARLFAMLRHPNIIQLRGVCLRQPHLCLVLEFARGGALNRALAAAASDPRAPGPRRARRIPPQVLVNWAVQIARGMLYLHEEAVVPILHRDLKSSNI 253          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: ROCO4_DICDI (Probable serine/threonine-protein kinase roco4 OS=Dictyostelium discoideum GN=roco4 PE=3 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 3.220e-13
Identity = 48/138 (34.78%), Postives = 69/138 (50.00%), Query Frame = 1

Query:  229 EITLGERIGLGSYGEVYRGDW--HGTEVAVKRFLDQDFFGES-----LEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLHNCTPVIVHRDLKSPNL 621
            EI   ++IG G +G V++G      + VA+K  +  D  GE+      +EF+ EV IM  + HPN+V   G +  PP +  V EF+P G LY  L    +                G+ Y+ N  P IVHRDL+SPN+
Sbjct: 1025 EIEYEKQIGKGGFGLVHKGRLVKDKSVVAIKSLILGDSEGETEMIEKFQEFQREVFIMSNLNHPNIVKLYGLMHNPPRM--VMEFVPCGDLYHRLLDKAHPIKWSVKLRLMLDIALGIEYMQNQNPPIVHRDLRSPNI 1160          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: YTYK2_DICDI (Probable tyrosine-protein kinase DDB_G0283397 OS=Dictyostelium discoideum GN=DDB_G0283397 PE=3 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 4.206e-13
Identity = 54/143 (37.76%), Postives = 73/143 (51.05%), Query Frame = 1

Query:  214 EIPWEEITLGERIGLGSYGEVYRGDWHGTEVAVKRFLDQDFFG-ESLEEFRSEVLIMKRVRHPNVVLFMGA--VTRPPN-LSIVTEFLPRGSLYRLL-HRPNNQXXXXXXXXXXXXXXXGMNYLHN--CTPVIVHRDLKSPNL 621
            EIP  E+T+ + IG G +G+VY+  W G  VA+K+     F      E F  EV IM ++ HP  V+F+GA  +  P N  SI+ E++  GSL RLL  + +                 GMNYLH       IVHRDL S N+
Sbjct:  171 EIPSRELTVEKEIGQGFFGKVYKARWRGKSVALKKITLIKFRDLTETEIFDKEVSIMSKLCHPTCVMFIGACSLDGPSNDRSIIMEYMEGGSLRRLLDEKSSYHLPPSLQLSIARDIAEGMNYLHTNFKEGPIVHRDLTSSNI 313          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: M3K11_RAT (Mitogen-activated protein kinase kinase kinase 11 OS=Rattus norvegicus GN=Map3k11 PE=2 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 4.206e-13
Identity = 47/141 (33.33%), Postives = 67/141 (47.52%), Query Frame = 1

Query:  211 CEIP-WEEITLGERIGLGSYGEVYRGDWHGTEVAVK--RFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLH-NCTPVIVHRDLKSPNL 621
            CE+  ++E+ L E IG+G +G+VYRG W G  VAVK  R    +    + E  R E  +   + HPN++         PNL +V E+   G L R L     +               GM+YLH      ++HRDLKS N+
Sbjct:  110 CEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRAL--AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNI 248          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: M3K11_MOUSE (Mitogen-activated protein kinase kinase kinase 11 OS=Mus musculus GN=Map3k11 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 4.206e-13
Identity = 47/141 (33.33%), Postives = 67/141 (47.52%), Query Frame = 1

Query:  211 CEIP-WEEITLGERIGLGSYGEVYRGDWHGTEVAVK--RFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLH-NCTPVIVHRDLKSPNL 621
            CE+  ++E+ L E IG+G +G+VYRG W G  VAVK  R    +    + E  R E  +   + HPN++         PNL +V E+   G L R L     +               GM+YLH      ++HRDLKS N+
Sbjct:  110 CEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRAL--AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNI 248          

BLAST of CF503945 vs. ExPASy Swiss-Prot
Match: M3K11_HUMAN (Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens GN=MAP3K11 PE=1 SV=1)

HSP 1 Score: 74.7146 bits (182), Expect = 4.206e-13
Identity = 47/141 (33.33%), Postives = 67/141 (47.52%), Query Frame = 1

Query:  211 CEIP-WEEITLGERIGLGSYGEVYRGDWHGTEVAVK--RFLDQDFFGESLEEFRSEVLIMKRVRHPNVVLFMGAVTRPPNLSIVTEFLPRGSLYRLLHRPNNQXXXXXXXXXXXXXXXGMNYLH-NCTPVIVHRDLKSPNL 621
            CE+  ++E+ L E IG+G +G+VYRG W G  VAVK  R    +    + E  R E  +   + HPN++         PNL +V E+   G L R L     +               GM+YLH      ++HRDLKS N+
Sbjct:  109 CEVASFQELRLEEVIGIGGFGKVYRGSWRGELVAVKAARQDPDEDISVTAESVRQEARLFAMLAHPNIIALKAVCLEEPNLCLVMEYAAGGPLSRAL--AGRRVPPHVLVNWAVQIARGMHYLHCEALVPVIHRDLKSNNI 247