CF833015

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP3AP_MOUSE (Cytochrome P450 3A25 OS=Mus musculus GN=Cyp3a25 PE=2 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 9.949e-14
Identity = 42/131 (32.06%), Postives = 71/131 (54.20%), Query Frame = 2

Query:  284 EEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            ++ L++ E+ A  +     G D +S++I   + EL  HP V  ++Q E+D  +     VT   L  + YL  V+ E  RL+P   + L R + +  +ING  IPKG+ +++ I+ + R+P  W +P EF P
Sbjct:  287 QKALSDLEMAAQAVIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMDMEYLDMVVNESLRLYP-IAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCP 416          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP2CC_RAT (Cytochrome P450 2C12, female-specific OS=Rattus norvegicus GN=Cyp2c12 PE=2 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 9.949e-14
Identity = 41/136 (30.15%), Postives = 72/136 (52.94%), Query Frame = 2

Query:  269 DDANGEEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            ++ N +   T+  +  L+ N+F  GT+TSS T+ +A+  L+++P +  +VQ+E+  V+GR R    LD   + Y  A+I E+ R     P  L    +   K   Y IPKG+ +L ++ ++     E+ +P  F P
Sbjct:  274 ENGNQQMNYTQEHLAILVTNLFIGGTETSSLTLRFALLLLMKYPHITDKVQEEIGQVIGRHRSPCMLDRIHMPYTNAMIHEVQRYIDLAPNGLLHEVTCDTKFRDYFIPKGTAVLTSLTSVLHARKEFPNPEMFDP 409          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP46A_MOUSE (Cholesterol 24-hydroxylase OS=Mus musculus GN=Cyp46a1 PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.299e-13
Identity = 49/164 (29.88%), Postives = 83/164 (50.61%), Query Frame = 2

Query:  185 DILEERKMNGRDGGNKLTDLLGTLISLMDDANGEEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            D ++ R+   + G +   D+L  ++   + A  +E L +       +  F AG +TS++ + + + EL R P++ A++Q E+D VVG  R +   DL +L YL  V+KE  RL+P       R   E   I+G  +P  + LL + + + R    + DPL F P
Sbjct:  256 DWVQRRREALKRGEDMPADILTQILKAEEGAQDDEVLLDN-----FVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVVGSKRHLDYEDLGRLQYLSQVLKESLRLYPPA-WGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNP 413          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP2E1_BOVIN (Cytochrome P450 2E1 OS=Bos taurus GN=CYP2E1 PE=2 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.299e-13
Identity = 38/127 (29.92%), Postives = 72/127 (56.69%), Query Frame = 2

Query:  296 TETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            T   I   + ++  AGT+T+S+T+ + +  L+++P+V  ++ +E+D V+G  R+    D   + YL AV+ EI R     P +L   A++     GY IPKG+ ++  + ++  D  E+ +P +F+P
Sbjct:  285 TLENIAVTVADLLFAGTETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRIPAVKDRLDMPYLDAVVHEIQRFIDLLPSNLLHEATQDTVFRGYVIPKGTVVIPTLDSVLHDRQEFPEPEKFKP 411          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP2CD_RAT (Cytochrome P450 2C13, male-specific OS=Rattus norvegicus GN=Cyp2c13 PE=1 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.299e-13
Identity = 42/136 (30.88%), Postives = 73/136 (53.68%), Query Frame = 2

Query:  269 DDANGEEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            ++AN     T   +  ++ ++F AG +T SST+ +A+  L+++P V A+VQ+E+D V+GR R     D   + Y  A++ E+ R     P  L    +   K   Y IPKG+ +L ++ ++  D  E+ +P  F P
Sbjct:  274 ENANQWMNYTLEHLAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTNAMVHEVQRYIDIGPNGLLHEVTCDTKFRNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDP 409          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: C513C_DICDI (Probable cytochrome P450 513C1 OS=Dictyostelium discoideum GN=cyp513c1 PE=3 SV=1)

HSP 1 Score: 76.6406 bits (187), Expect = 1.299e-13
Identity = 39/131 (29.77%), Postives = 75/131 (57.25%), Query Frame = 2

Query:  290 KLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQEL-DSVVGRDRLVTELDLPQ-LTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            ++T+  + ++ +++  AGTDT   T+ +AI  L+ + ++  ++ + + DS+   D   +       + YL  V+KE+FR++P+  L LP   SE C+I G+ I KG+ ++ NI++  R  + W +P  F P
Sbjct:  290 RITQNALISICIDVLIAGTDTVGQTLSFAIVALVNNAEIQEKLSRNIIDSMEKGDNHYSYSKYRNGIPYLALVVKEVFRMYPAGILGLPHMTSEDCEIQGHKIAKGTQIIQNIYSTHRSESFWPNPNNFIP 420          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP27A_RAT (Sterol 26-hydroxylase, mitochondrial OS=Rattus norvegicus GN=Cyp27a1 PE=1 SV=1)

HSP 1 Score: 76.2554 bits (186), Expect = 1.697e-13
Identity = 38/131 (29.01%), Postives = 71/131 (54.20%), Query Frame = 2

Query:  284 EEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            +E L+  E       +  AG DT+S+T+ WA+  L ++P++   + +E+  VV   ++    D   +  L+AVIKE  RL+P  P +      +  +ING+  PK +  ++  + ++RDP+ + +P  F+P
Sbjct:  319 KELLSPQETVGTFPELILAGVDTTSNTLTWALYHLSKNPEIQEALHKEVTGVVPFGKVPQNKDFAHMPLLKAVIKETLRLYPVVPTNSRIITEKETEINGFLFPKNTQFVLCHYVVSRDPSVFPEPESFQP 449          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP46A_HUMAN (Cholesterol 24-hydroxylase OS=Homo sapiens GN=CYP46A1 PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 2.216e-13
Identity = 48/164 (29.27%), Postives = 82/164 (50.00%), Query Frame = 2

Query:  185 DILEERKMNGRDGGNKLTDLLGTLISLMDDANGEEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            D ++ R+   + G     D+L  ++   + A  +E L +       +  F AG +TS++ + + + EL R P++ A++Q E+D V+G  R +   DL +L YL  V+KE  RL+P       R   E   I+G  +P  + LL + + + R    + DPL F P
Sbjct:  256 DWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDN-----FVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLGRLQYLSQVLKESLRLYPPA-WGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNP 413          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP2BA_MOUSE (Cytochrome P450 2B10 OS=Mus musculus GN=Cyp2b10 PE=1 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 2.216e-13
Identity = 39/136 (28.68%), Postives = 70/136 (51.47%), Query Frame = 2

Query:  269 DDANGEEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            + +N   +     +   +L++F  GT+TSS+T+ +    ++++P V  +VQ+E+D V+G  RL T  D  ++ Y  AVI EI R     P+ +P   ++     GY +PK + +   + +   DP  +  P  F P
Sbjct:  275 EKSNQNAEFHHQNLMMSVLSLFFVGTETSSTTLHYGFLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYSDAVIHEIQRFSDLIPIGVPHRVTKDTLFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNP 410          

BLAST of CF833015 vs. ExPASy Swiss-Prot
Match: CP139_MYCTU (Putative cytochrome P450 139 OS=Mycobacterium tuberculosis GN=cyp139 PE=3 SV=1)

HSP 1 Score: 75.8702 bits (185), Expect = 2.216e-13
Identity = 53/179 (29.61%), Postives = 85/179 (47.49%), Query Frame = 2

Query:  140 RKMKKLHKRFDVFLSDILEERKMNGRDGGNKLTDLLGTLISLMDDANGEEKLTETEIKALLLNMFTAGTDTSSSTIEWAIAELIRHPKVWAQVQQELDSVVGRDRLVTELDLPQLTYLQAVIKEIFRLHPSTPLSLPRAASESCKINGYDIPKGSTLLVNIWAIARDPNEWADPLEFRP 676
            R+     KR D    D+++ +  + R        +L TLIS   +      L++ EI+  ++++ TAG +T+S  + WAI  L+  P  W     E+  V+G  R+    DL  LTYL  V+ E  RL+    +S  R   +    +G+ I  G  L+ + +   R P  W +P EFRP
Sbjct:  174 RRAMAARKRID----DLIDAQIADARTAPRPDDHMLTTLISGCSEEG--TTLSDNEIRDSIVSLITAGYETTSGALAWAIYALLTVPGTWESAASEVARVLG-GRVPAADDLSALTYLNGVVHETLRLYSPGVISARRVLRD-LWFDGHRIRAGRLLIFSAYVTHRLPEIWPEPTEFRP 344