CF836429

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: CFTR_TRIVU (Cystic fibrosis transmembrane conductance regulator OS=Trichosurus vulpecula GN=CFTR PE=2 SV=1)

HSP 1 Score: 125.946 bits (315), Expect = 2.447e-28
Identity = 83/280 (29.64%), Postives = 129/280 (46.07%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAWKME-----------------DRLPPPNWPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            S++L +L+S  + P+  H   S+ G+ T+RAFG+Q  F       +N +    F    +  W   R+E++    FC+ T   IL                        L WA+  S  V++ M SV R+ +F ++PSE     +                 + +   NWP+ G + + DL  +Y      VL+ I+ SI  G+++G++GRTGSGKSTL+  F RL+  +                   R  FG+IPQ+  +F GT R N+DP GQ+SD E
Sbjct: 1036 SQQLKQLESEARTPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYMSTLRWFQMRIEIIFVTFFCIVTFISILTTGD--GEGRVGILLTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFIDMPSEEPLPPKPTKSKKNQLSQVLIIENEHVKKENWPSGGQMTVKDLTAKYIDGGNAVLENISFSISSGQRVGLLGRTGSGKSTLLAAFLRLLN-TQGDIQIDGVSWDSVPLQQWRKAFGVIPQKVFIFSGTFRKNLDPYGQWSDHE 1312          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: ABCC8_CRICR (ATP-binding cassette transporter sub-family C member 8 OS=Cricetus cricetus GN=ABCC8 PE=1 SV=3)

HSP 1 Score: 125.946 bits (315), Expect = 2.447e-28
Identity = 84/266 (31.58%), Postives = 129/266 (48.50%), Query Frame = -3

Query:    9 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLF----WAIYMSCFVENRMVSVERIKQFTEIPSEA-AWKMEDRLPPPNWPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSD 791
            SR+L +LD  T+ P++ HF+E++ G+ TIRAF  +  F Q+ +   + N         +N WL   +E +G+    +A    I   S+ +  E               +     W +     +E ++ +V+RI    +  +E+    +   L P NWP  G + + +L VRY S+   VLK +   I  G+KIG+ GRTGSGKS+    FFR+V+                    LRSR  II Q+PVLF GT+R N+DP  + SD
Sbjct: 1186 SRDLQQLDDTTQLPLVSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVCMEYIGACVVLIAAATSI---SNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHALLKTEAESYEGLLAPSLIPKNWPDQGKIQIQNLSVRYDSSLKPVLKHVNTLISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSD 1448          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: MDR_LEITA (Multidrug resistance protein OS=Leishmania tarentolae GN=PGPA PE=3 SV=2)

HSP 1 Score: 124.405 bits (311), Expect = 7.121e-28
Identity = 95/302 (31.46%), Postives = 130/302 (43.05%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLF--------WAIYMSCFVENRMVSVERIKQFTE-------------------------------IPSEAAWKMEDRLPPPNWPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            +RE  R+ SI  +PV     ES+ G  TI  +GK     QE + R++      +  N SN WLG RLE L     C+ T FM+     I K E               +         W +     VE  M SVER+  +T+                               +  E+A      L P      G++ L  +Q+RYR   PLVL+G++  I   EK+G+VGRTGSGKSTL+  F R+VE                    +R  F +IPQ+PVLF+GTVR N+DP  + S  E
Sbjct: 1098 NRETRRIKSIAHSPVFTLLEESLQGQRTIATYGKLHLVLQEALGRLDVVYSALYMQNVSNRWLGVRLEFLS----CVVT-FMVAFIGVIGKMEGASSQNIGLISLSLTMSMTLTETLNWLVRQVAMVEANMNSVERVLHYTQEVEHEHVPEMGELVAQLVRSESGRGANVTETVVIESAGAASSALHPVQ---AGSLVLEGVQMRYREGLPLVLRGVSFQIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGVIHVNGREMSAYGLRDVRRHFSMIPQDPVLFDGTVRQNVDPFLEASSAE 1391          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: CFTR_ORNAN (Cystic fibrosis transmembrane conductance regulator OS=Ornithorhynchus anatinus GN=CFTR PE=3 SV=1)

HSP 1 Score: 122.865 bits (307), Expect = 2.072e-27
Identity = 84/284 (29.58%), Postives = 131/284 (46.13%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAWKMEDRLPPP---------------------NWPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            S++L +L+S  ++P+  H   S+ G+ T+RAFG+QT F       +N +    F    +  W   R+E++    F L T   IL                        L WA+  S  V++ M SV R+ +F ++P+E     E R   P                     NWP+ G + + DL  +Y    P +L  I+ SI  G+++G++GRTGSGKSTL+  F RL+  +                   R  FG+IPQ+  +F G+ R N+DP GQ++D+E
Sbjct: 1041 SQQLKQLESEARSPIFTHLITSLKGLWTLRAFGRQTYFEALFHKALNLHTANWFLYLSTLRWFQMRIEMVFVIFFILVTFISILTTGD--GEGKVGIVLTLAMNIMGTLQWAVNASIDVDSLMRSVSRVFKFIDMPTE-----EHRPTHPAKNKDISGVLIIENQHVKREKNWPSGGQMTVQDLTAKYLDGGPAILDNISFSISSGQRVGLLGRTGSGKSTLLFAFLRLLN-TEGDIRIDGISWDAVPVQQWRKAFGVIPQKVFIFSGSFRKNLDPYGQWTDQE 1316          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: ABC4_SCHPO (ATP-binding cassette transporter abc4 OS=Schizosaccharomyces pombe GN=abc4 PE=2 SV=1)

HSP 1 Score: 120.553 bits (301), Expect = 1.028e-26
Identity = 78/256 (30.47%), Postives = 117/256 (45.70%), Query Frame = -3

Query:    9 RLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAWKMEDRLPPPNWPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSD 776
            RL SI  +P+     ESI GV  IRAF +QT F Q    R++  +R+   +   N W+  R + +      +A L  +L     + P                +   +     ++  M S ER+ +++++P E A  +  ++P   WP  G++    + V Y +  P +LK + L I+  EK+ VVGRTGSGKSTL     R                       LR R   IPQ+P+LF GTVRSN+DP  +  D
Sbjct: 1063 RLISIYTSPIFSLLGESIVGVSVIRAFNRQTIFKQMFSERLDNLVRLQSTSYNLNRWVAVRTDGISGLVGAIAGLIALLQKD--LSPGVVGFSLNQAVIFSSSVLLFVRSCNSLQAEMNSYERVLEYSKLPQEPAPTIAGQVPA-TWPKEGDIVFNHVSVSYSAAGPTILKDVNLHINPSEKVAVVGRTGSGKSTLGLTLLRFTHRISGEIYINGRETQSVNLNALRQRISFIPQDPILFSGTVRSNLDPFDELED 1315          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: CFTR_LOXAF (Cystic fibrosis transmembrane conductance regulator OS=Loxodonta africana GN=CFTR PE=3 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 1.754e-26
Identity = 82/282 (29.08%), Postives = 129/282 (45.74%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAWKMEDRLPPP-------------------NWPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            S++L +L+S  ++P+  H   S+ G+ T+RAFG+Q  F       +N +    F    +  W   R+E++    F   T   IL                        L WA+  S  V++ M SV RI +F ++P+E +   +   PP                    NWP+ G++ + DL  +Y      +L+ I+ SI  G+++G++GRTGSGKSTL+  F RL+  +                   R  FG+IPQ+  +F GT R N+DP  Q SD+E
Sbjct: 1038 SQQLKQLESEARSPIFTHLVTSVKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRIEIIFVIFFIAVTFVSILTTGE--GEGTIGIILTLAMNIMNTLQWAVNSSIDVDSLMRSVSRIFKFIDMPTEESKPAKSVKPPKDGQLSKVMIIENQHVKKDYNWPSGGHMTVKDLTAKYIDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYEQCSDQE 1316          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: CFTR_DASNO (Cystic fibrosis transmembrane conductance regulator OS=Dasypus novemcinctus GN=CFTR PE=3 SV=1)

HSP 1 Score: 118.627 bits (296), Expect = 3.907e-26
Identity = 82/282 (29.08%), Postives = 129/282 (45.74%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAWKMED-RLPPPN------------------WPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            S++L +L+S  ++P+  H   S+ G+ T+RAFG+Q  F       +N +    F    +  W   R+E++    F   T   IL                        L WA+  S  V++ M SV R+ +F +IP+E     +  +LP                     WP+ G + + DL  +Y      +L+ I+ SI  G+++G++GRTGSGKSTL+  F RL+  +                   R  FG+IPQ+  +F GT R N+DP GQ+SD+E
Sbjct: 1038 SQQLKQLESEARSPIFTHLVTSLKGLWTLRAFGRQPYFEALFHKALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGE--GEGTVGIILTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFVDIPTEENKPTKSIKLPKDGQLSKVMIIENQHVKKDDIWPSGGQMTVKDLTAKYIDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TKGEIQIDGVSWDSITLQEWRKAFGVIPQKVFIFSGTFRKNLDPYGQWSDQE 1316          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: CFTR_DIDMA (Cystic fibrosis transmembrane conductance regulator OS=Didelphis marsupialis virginiana GN=CFTR PE=3 SV=1)

HSP 1 Score: 117.472 bits (293), Expect = 8.704e-26
Identity = 83/282 (29.43%), Postives = 126/282 (44.68%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAW-------------------KMEDRLPPPNWPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            S++L +L+S  + P+  H   S+ G+ T+RAFG+Q  F       +N +    F    +  W   R+EL+    F   T   IL                        L WA+  S  V++ M SV R+ +F ++P+E                      + E      NWP+ G + + DL  +Y      VL+ I+ SI  G+++G++GRTGSGKSTL+  F RL+  +                   R  FG+IPQ+  +F GT R N+DP GQ+SD E
Sbjct: 1038 SQQLKQLESEARTPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTASWFLYLSTLRWFQMRIELVFVIFFIAVTFISILTTGD--GEGRVGILLTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEEPLPAKPTKSLKKNQLSQVLIIENEHVNKENNWPSGGQMIVKDLTAKYTDGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLAAFLRLLN-TEGEMQIDGVSWDSIPLQKWRKAFGVIPQKVFIFSGTFRKNLDPYGQWSDHE 1316          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: CFTR_HORSE (Cystic fibrosis transmembrane conductance regulator OS=Equus caballus GN=CFTR PE=3 SV=1)

HSP 1 Score: 117.087 bits (292), Expect = 1.137e-25
Identity = 79/282 (28.01%), Postives = 129/282 (45.74%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAWKMEDRLPPPN-------------------WPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            S++L +L+S  ++P+  H   S+ G+ T+RAFG+Q  F       +N +    F    +  W   R+E++    F   T   IL                        L WA+  S  V++ M SV R+ +F ++P+E +   +   P  +                   WP+ G + + DL  +Y      +L+ I+ SI  G+++G++GRTGSGKSTL+  F RL+  +                   R  FG+IPQ+  +F GT R N+DP GQ++D+E
Sbjct: 1037 SQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRIEMIFVIFFIAVTFISILTTGE--GEGTVGIILTLAMNIMSTLQWAVNSSIDVDSLMRSVSRVFKFIDMPTEDSKPTKSVKPSKDGQLSKVMIIENQYVKKDDIWPSGGQMTVKDLTAKYTDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGEIQIDGVSWDSITLQQWRKAFGVIPQKVFIFSGTFRKNLDPYGQWNDQE 1315          

BLAST of CF836429 vs. ExPASy Swiss-Prot
Match: CFTR_MUSPF (Cystic fibrosis transmembrane conductance regulator OS=Mustela putorius furo GN=CFTR PE=3 SV=1)

HSP 1 Score: 116.701 bits (291), Expect = 1.485e-25
Identity = 78/283 (27.56%), Postives = 127/283 (44.88%), Query Frame = -3

Query:    3 SRELTRLDSITKAPVIHHFSESISGVMTIRAFGKQTTFYQENVNRVNGNLRMDFHNNGSNEWLGFRLELLGSFTFCLATLFMILLPSSIIKPEXXXXXXXXXXXXXXXLFWAIYMSCFVENRMVSVERIKQFTEIPSEAAWKMEDRLPPPN--------------------WPAHGNVDLIDLQVRYRSNTPLVLKGITLSIHGGEKIGVVGRTGSGKSTLIQVFFRLVEPSXXXXXXXXXXXXXXXXXXLRSRFGIIPQEPVLFEGTVRSNIDPIGQYSDEE 791
            S++L +L+S  ++P+  H   S+ G+ T+RAFG+Q  F       +N +    F    +  W   R+E++    F   T   IL     +                    WA+  S  V++ M SV R+ +F ++P+E +        P                      WP+ G + + DL  +Y      +L+ I+ SI  G+++G++GRTGSGKSTL+  F RL+  +                   R  FG+IPQ+  +F GT R N+DP GQ++D+E
Sbjct: 1039 SQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFGRQPYFETLFHKALNLHTANWFLYLSTLRWFQMRMEIIFVIFFIAITFISILTTGEGVGAVGIILTLAMNIMGTLQ--WAVNSSIDVDSLMRSVSRVFKFIDMPAEESKPPTKSFKPSKDVQLSKVLITENHHVREDDIWPSGGQMTVKDLTAKYIDGGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLN-TEGEIQIDGVSWDSITLQEWRKAFGVIPQKVFIFSGTFRKNLDPYGQWNDQE 1318