CK739758

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: M3K1_MOUSE (Mitogen-activated protein kinase kinase kinase 1 OS=Mus musculus GN=Map3k1 PE=1 SV=3)

HSP 1 Score: 85.1149 bits (209), Expect = 4.501e-20
Identity = 42/112 (37.50%), Postives = 66/112 (58.93%), Query Frame = 2

Query:    2 SDDRLVIQDFRHEVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNSSADHLKVGDFG 337
            S+   V++  R E+ ++  L HPNI++ LGA  E+    L  E++ GG +   L + GA   S  +N+   + RG++YLH   N IIHRD+K  N LL++S+   L++ DFG
Sbjct: 1263 SEQEEVVEALREEIRMMGHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHE--NQIIHRDVKGAN-LLIDSTGQRLRIADFG 1371          

HSP 2 Score: 33.4982 bits (75), Expect = 4.501e-20
Identity = 14/38 (36.84%), Postives = 23/38 (60.53%), Query Frame = 1

Query:  397 GSYRYMAPEVFKHRKYDKKVDVFSFAMILYEMLEGEPP 510
            G+  +MAPEV + ++Y +  DV+S    + EM   +PP
Sbjct: 1392 GTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPP 1429          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: DRKC_DICDI (Probable serine/threonine-protein kinase drkC OS=Dictyostelium discoideum GN=drkC PE=3 SV=1)

HSP 1 Score: 79.7221 bits (195), Expect = 4.556e-20
Identity = 44/118 (37.29%), Postives = 66/118 (55.93%), Query Frame = 2

Query:    5 DDRLVIQDFRHEVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKG-ALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLIK 355
            DD   + +   E  ++ +LRHPNI QFLG       ++++ EY+  G L++ L +   +L      + ALDIA+GM YLH    ++IHRDLK  N+L+       +K+ DFGLS   K
Sbjct:  526 DDEDFLNELAQEATIMSQLRHPNICQFLGTCNNPPEILIVMEYMPLGSLYRILHDPSISLDWPRMKSMALDIAKGMNYLHCCDPIVIHRDLKSHNLLV--DEHYRVKISDFGLSTRFK 641          

HSP 2 Score: 38.891 bits (89), Expect = 4.556e-20
Identity = 17/38 (44.74%), Postives = 27/38 (71.05%), Query Frame = 1

Query:  397 GSYRYMAPEVFKHRKYDKKVDVFSFAMILYEMLEGEPP 510
            G+  + APEV ++  Y +K DVFSFA++L+E++  E P
Sbjct:  654 GTPCWTAPEVLRNDPYTEKADVFSFAIVLWEIVTREDP 691          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: IPL1_YARLI (Spindle assembly checkpoint kinase OS=Yarrowia lipolytica GN=IPL1 PE=3 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 4.621e-20
Identity = 40/109 (36.70%), Postives = 64/109 (58.72%), Query Frame = 2

Query:   17 VIQDFRHEVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNSSADHLKVGDFGLS 343
            V + FR EV +   LRH N+++  G   ++  + LI EY+  G+L+K L+ +   + STA ++   ++  + YLH +   IIHRD+KP N+LL     D +K+ DFG S
Sbjct:  140 VEKQFRREVEIQSNLRHTNVLRLFGHFHDKDRVYLILEYVVHGELYKLLRNQKRFTESTASSYIYQMSEALLYLHGKN--IIHRDIKPENILL--HFNDTIKISDFGWS 244          

HSP 2 Score: 44.2838 bits (103), Expect = 4.621e-20
Identity = 18/38 (47.37%), Postives = 26/38 (68.42%), Query Frame = 1

Query:  397 GSYRYMAPEVFKHRKYDKKVDVFSFAMILYEMLEGEPP 510
            G+  Y+ PE+ + R YDK VDV+S  +++YE L G PP
Sbjct:  257 GTMDYLPPEIVQSRPYDKNVDVWSLGILMYEFLCGAPP 294          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: ROC11_DICDI (Probable serine/threonine-protein kinase roco11 OS=Dictyostelium discoideum GN=roco11 PE=3 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 5.853e-20
Identity = 41/111 (36.94%), Postives = 66/111 (59.46%), Query Frame = 2

Query:   23 QDFRHEVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNSSADH---LKVGDFGLSK 346
            Q+F HE+ ++  L H NIV+  G++  + P  ++ E+   GDL+ +L++K  +  S  V   LDIA+G+ YL N+   I+HRDL+  N+ L +   +     KV DFGLS+
Sbjct: 1233 QEFHHEMYIMSSLNHLNIVKLFGSM--QNPPRMVMEFAPHGDLYHFLEKKKNIKWSFKVRLMLDIAKGIEYLQNQNPPIVHRDLRSPNIFLFSLDENAPVCAKVADFGLSQ 1341          

HSP 2 Score: 42.743 bits (99), Expect = 5.853e-20
Identity = 18/57 (31.58%), Postives = 35/57 (61.40%), Query Frame = 1

Query:  382 MTGETGSYRYMAPEVF-KHRKYDKKVDVFSFAMILYEMLEGEPPLANYEPYEAAKYV 549
            ++G  G++++MAPE       Y +K+D +SF+MIL+ +L GE P   +  +   +++
Sbjct: 1347 VSGLLGNFQWMAPETIGAEESYTEKIDTYSFSMILFTILTGECPFDEFTSFGKMEFI 1403          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: ULK2_MOUSE (Serine/threonine-protein kinase ULK2 OS=Mus musculus GN=Ulk2 PE=1 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 5.890e-20
Identity = 44/112 (39.29%), Postives = 60/112 (53.57%), Query Frame = 2

Query:   38 EVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLL-------VNSSADHLKVGDFGLSKLI 352
            E+ +L +L+H NIV           + L+ EY  GGDL  YL+ KG LS  T   F   IA  M  LH++   IIHRDLKP+N+LL        N S   +K+ DFG ++ +
Sbjct:   56 EIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKG--IIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYL 165          

HSP 2 Score: 44.2838 bits (103), Expect = 5.890e-20
Identity = 19/46 (41.30%), Postives = 27/46 (58.70%), Query Frame = 1

Query:  397 GSYRYMAPEVFKHRKYDKKVDVFSFAMILYEMLEGEPPLANYEPYE 534
            GS  YMAPEV   + YD K D++S   ++Y+ L G+PP     P +
Sbjct:  176 GSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQD 221          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: TESK1_RAT (Dual specificity testis-specific protein kinase 1 OS=Rattus norvegicus GN=Tesk1 PE=1 SV=1)

HSP 1 Score: 77.0258 bits (188), Expect = 5.945e-20
Identity = 43/106 (40.57%), Postives = 62/106 (58.49%), Query Frame = 2

Query:   38 EVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNSSADHLK-VGDFGLSKLI 352
            EV L+ +LRHPNI++F+G    +  L  +TEY+ GG L + L     LS    ++ ALDIA+G+ YLH +   + HRDL  +N L+          VGDFGL++ I
Sbjct:   95 EVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKG--VFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKI 198          

HSP 2 Score: 41.2022 bits (95), Expect = 5.945e-20
Identity = 19/44 (43.18%), Postives = 28/44 (63.64%), Query Frame = 1

Query:  397 GSYRYMAPEVFKHRKYDKKVDVFSFAMILYEMLEGEPPLANYEP 528
            GS  +MAPEV +   YD+K DVF+F ++L E++   P   +Y P
Sbjct:  214 GSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLP 257          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: TXK_MOUSE (Tyrosine-protein kinase TXK OS=Mus musculus GN=Txk PE=1 SV=1)

HSP 1 Score: 81.6481 bits (200), Expect = 5.965e-20
Identity = 45/111 (40.54%), Postives = 68/111 (61.26%), Query Frame = 2

Query:   23 QDFRHEVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKE-KGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNSSADHLKVGDFGLSKLI 352
            +DF  E  +++KL H  +VQ  G   ++KPL ++TE++  G L  YL+E KG L  +  ++   DI  GMAYL  E +  IHRDL  RN L+  SSA  +K+ DFG+++ +
Sbjct:  309 EDFIEEAKVMMKLSHSRLVQLYGVCIQQKPLYIVTEFMENGCLLDYLRERKGQLQKALLLSMCQDICEGMAYL--ERSCYIHRDLAARNCLV--SSACVVKISDFGMARYV 415          

HSP 2 Score: 36.5798 bits (83), Expect = 5.965e-20
Identity = 17/49 (34.69%), Postives = 28/49 (57.14%), Query Frame = 1

Query:  376 VQMTGETGSYRYMAPEVFKHRKYDKKVDVFSFAMILYEML-EGEPPLAN 519
            +  +G     ++  PEVF   KY  K DV+SF ++++E+  EG+ P  N
Sbjct:  421 ISSSGAKFPVKWCPPEVFHFNKYSSKSDVWSFGVLMWEVFTEGKMPFEN 469          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: QKGA_DICDI (Probable serine/threonine-protein kinase qkgA OS=Dictyostelium discoideum GN=qkgA-1 PE=3 SV=2)

HSP 1 Score: 73.559 bits (179), Expect = 7.606e-20
Identity = 45/132 (34.09%), Postives = 72/132 (54.55%), Query Frame = 2

Query:   23 QDFRHEVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEK---GALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVN---SSADHLKVGDFGLSKLIKGQNSHDVYK*LGRLG 400
            Q+F+HEV ++  L HPNIV+  G +    P  ++ EY+  GDL+   ++K    +L  +  +   +DIA+G+ Y+ N+   I+HRDL+  N+ L +   +S    K+ DFGLS+         VY   G LG
Sbjct: 1310 QEFQHEVFIMSNLNHPNIVKLYGLM--HNPPRMVMEYVEHGDLYHLCQDKERYASLGWTLKLRLMIDIAKGIGYMQNQNPPIVHRDLRSPNIFLKSLDENSPVCAKIADFGLSQ-------QSVYSVSGLLG 1432          

HSP 2 Score: 44.2838 bits (103), Expect = 7.606e-20
Identity = 21/49 (42.86%), Postives = 32/49 (65.31%), Query Frame = 1

Query:  382 MTGETGSYRYMAPEVF--KHRKYDKKVDVFSFAMILYEMLEGEPPLANY 522
            ++G  G++++MAPE    +   Y +KVD +SFAMIL+ +L GE P   Y
Sbjct: 1427 VSGLLGNFQWMAPETIGVEDESYTEKVDTYSFAMILFTILTGEIPFDEY 1475          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: TESK1_MOUSE (Dual specificity testis-specific protein kinase 1 OS=Mus musculus GN=Tesk1 PE=2 SV=3)

HSP 1 Score: 76.6406 bits (187), Expect = 7.732e-20
Identity = 43/106 (40.57%), Postives = 62/106 (58.49%), Query Frame = 2

Query:   38 EVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNSSADHLK-VGDFGLSKLI 352
            EV L+ +LRHPNI++F+G    +  L  +TEY+ GG L + L     LS    ++ ALDIA+G+ YLH +   + HRDL  +N L+          VGDFGL++ I
Sbjct:   95 EVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKG--VFHRDLTSKNCLVRREDRGFTAVVGDFGLAEKI 198          

HSP 2 Score: 41.2022 bits (95), Expect = 7.732e-20
Identity = 19/44 (43.18%), Postives = 28/44 (63.64%), Query Frame = 1

Query:  397 GSYRYMAPEVFKHRKYDKKVDVFSFAMILYEMLEGEPPLANYEP 528
            GS  +MAPEV +   YD+K DVF+F ++L E++   P   +Y P
Sbjct:  214 GSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLP 257          

BLAST of CK739758 vs. ExPASy Swiss-Prot
Match: CDPK1_PLAFK (Calcium-dependent protein kinase 1 OS=Plasmodium falciparum (isolate K1 / Thailand) GN=CPK1 PE=1 SV=2)

HSP 1 Score: 77.7962 bits (190), Expect = 7.759e-20
Identity = 41/120 (34.17%), Postives = 65/120 (54.17%), Query Frame = 2

Query:    8 DRLVIQDFRHEVNLLVKLRHPNIVQFLGAVTERKPLMLITEYLRGGDLHKYLKEKGALSPSTAVNFALDIARGMAYLHNEPNVIIHRDLKPRNVLLVNS-SADHLKVGDFGLSKLIKGQN 364
            D  + ++  +E++LL  L HPNI++      ++K   L+TE+  GG+L + +  +       A N    I  G+ YLH   + I+HRD+KP N+LL N  S  ++K+ DFGLS      N
Sbjct:  106 DDKIHEEIYNEISLLKSLDHPNIIKLFDVFEDKKYFYLVTEFYEGGELFEQIINRHKFDECDAANIMKQILSGICYLHK--HNIVHRDIKPENILLENKHSLLNIKIVDFGLSSFFSKDN 223          

HSP 2 Score: 40.0466 bits (92), Expect = 7.759e-20
Identity = 24/64 (37.50%), Postives = 36/64 (56.25%), Query Frame = 1

Query:  358 SEFS*CVQMTGETGSYRYMAPEVFKHRKYDKKVDVFSFAMILYEMLEGEPPLANYEPYEAAKYV 549
            S FS   ++    G+  Y+APEV + +KY++K DV+S  +ILY +L G PP       +  K V
Sbjct:  217 SFFSKDNKLRDRLGTAYYIAPEVLR-KKYNEKCDVWSCGVILYILLCGYPPFGGQNDQDIIKKV 279