CK935253

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1D1_RABIT (3-oxo-5-beta-steroid 4-dehydrogenase OS=Oryctolagus cuniculus GN=AKR1D1 PE=2 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 1.481e-38
Identity = 68/167 (40.72%), Postives = 93/167 (55.69%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGT--VSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            Y+DLY++  P+A K    G      D +G      T +L  TW A+E     GLV+S+G+SN+     ++ L +  L   K KPV NQ E HPYF +  L+KFCQ+H I + A++PL G   N  W  T     L D +L  L +KYK+T AQIVLR+ +QR   VI
Sbjct:  113 YIDLYIIEIPMAFKP---GDVVYPRDENGKWLYHKT-NLCATWEALEACKDAGLVKSLGVSNFNRQQLELLLNKPGL---KHKPVCNQVECHPYFTQPKLLKFCQQHDIIIVAYSPL-GTCRNPMWVNTSLPPLLKDTLLNSLGKKYKKTAAQIVLRFNVQRGVVVI 271          

HSP 2 Score: 72.0182 bits (175), Expect = 1.481e-38
Identity = 42/103 (40.78%), Postives = 60/103 (58.25%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKI----GYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVL--EACKDSLKKLQLD 359
            I L +G  +PIIGLG +   ++  +     ++KI    GYRHID A  Y+NE EVGE   E  + G V+RED+F   KLW ++H  V+     + +LK L+LD
Sbjct:   10 IPLGDGNSIPIIGLGTYSEPKTTPKGSCATSVKIAIDTGYRHIDGAYIYQNEHEVGETFREKIAEGKVRREDIFYCGKLWATNHDPVMVRPTLERTLKVLKLD 112          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1D1_HUMAN (3-oxo-5-beta-steroid 4-dehydrogenase OS=Homo sapiens GN=AKR1D1 PE=1 SV=1)

HSP 1 Score: 105.916 bits (263), Expect = 2.513e-38
Identity = 68/167 (40.72%), Postives = 94/167 (56.29%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVS--CLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            Y+DLY++  P+A K    G      D +G      + +L  TW AME     GLV+S+G+SN+     ++ L +  L   K KPV NQ E HPYF +  L+KFCQ+H I +TA++PLG +  N  W    S   L D +L  L ++Y +T AQIVLR+ IQR   VI
Sbjct:  113 YVDLYIIEVPMAFKP---GDEIYPRDENGKWLYHKS-NLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGL---KHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTS-RNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVI 271          

HSP 2 Score: 74.3294 bits (181), Expect = 2.513e-38
Identity = 43/103 (41.75%), Postives = 62/103 (60.19%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKI----GYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            I L++G  +PIIGLG +   +S  +     ++K+    GYRHID A  Y+NE EVGEA+ E  + G V+RED+F   KLW ++H    V    + +L+ LQLD
Sbjct:   10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLD 112          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1A1_CRIGR (Alcohol dehydrogenase [NADP+] (Fragment) OS=Cricetulus griseus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 3.293e-38
Identity = 55/142 (38.73%), Postives = 83/142 (58.45%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKR 784
            YLDLYL+H+P A +    G      + DG +  D+T   ET W A+E LV+ GLV+++G+SN++     D L+ + V+P V Q E HPY  ++ L+  CQ  G+ VTA++PLG +            L++PV+  LAEK+ R
Sbjct:   91 YLDLYLMHWPYAFER---GDNPFPKNDDGTIRYDSTHYKET-WKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGR 228          

HSP 2 Score: 82.8037 bits (203), Expect = 3.293e-38
Identity = 43/90 (47.78%), Postives = 58/90 (64.44%), Query Frame = 3

Query:   99 IIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            +IGLG W+ +   ++  I  A+ +GYRHIDCAA Y NE E+GEAL E    G  V RE+LF+T+KLWN+ H    V  A + +L  LQL+
Sbjct:    1 LIGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLE 90          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1C1_HUMAN (Aldo-keto reductase family 1 member C1 OS=Homo sapiens GN=AKR1C1 PE=1 SV=1)

HSP 1 Score: 105.145 bits (261), Expect = 4.266e-38
Identity = 68/173 (39.31%), Postives = 94/173 (54.34%), Query Frame = 2

Query:  341 KEAPTGYLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVS--CLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            K     Y+DLYL+HFPV+ K    G      D +G +  DT + L  TW A+E     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPYF +  L+ FC+   I + A++ L G+     W    S   L+DPVL  LA+K+KRT A I LR+ +QR   V+
Sbjct:  104 KNLQLDYVDLYLIHFPVSVKP---GEEVIPKDENGKILFDT-VDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL-GSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268          

HSP 2 Score: 74.3294 bits (181), Expect = 4.266e-38
Identity = 43/102 (42.16%), Postives = 60/102 (58.82%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVW---RMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSLKKLQLD 359
            + LN+G  MP++G G +    + +S   +    AI+ G+RHID A  Y NE +VG A+    + G VKRED+F T+KLW + H    V  A + SLK LQLD
Sbjct:    8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLD 109          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1C1_PONAB (Aldo-keto reductase family 1 member C1 homolog OS=Pongo abelii GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 9.433e-38
Identity = 69/173 (39.88%), Postives = 95/173 (54.91%), Query Frame = 2

Query:  341 KEAPTGYLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVS--CLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            K     Y+DLYLVHFPV+ K    G      D +G +  DT + L  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPYF +  L+ FC+   I + A++ L G+    +W    S   L+DPVL  LA+K+K+T A I LR+ +QR   V+
Sbjct:  104 KNLQLDYVDLYLVHFPVSVKP---GEEVIPKDENGKILFDT-VDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL-GSHREEKWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVL 268          

HSP 2 Score: 72.0182 bits (175), Expect = 9.433e-38
Identity = 43/102 (42.16%), Postives = 58/102 (56.86%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSLKKLQLD 359
            + LN+   MP++G G +   E   S   +    AI+ G+RHID A  Y NE +VG A+    + G VKRED+F T+KLW + H    V  A + SLK LQLD
Sbjct:    8 VKLNDSHFMPVLGFGTYAPPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLD 109          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: PE2R_RABIT (Prostaglandin-E(2) 9-reductase OS=Oryctolagus cuniculus GN=AKR1C5 PE=1 SV=1)

HSP 1 Score: 101.293 bits (251), Expect = 2.717e-37
Identity = 63/173 (36.42%), Postives = 93/173 (53.76%), Query Frame = 2

Query:  341 KEAPTGYLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVS--CLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            K     Y+DLY++HFP A K    G      D  G    DT + +  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPY  +  L++FC+  GI + A++ L G+    EW    +   L+DP++  LA+K+++T A I LR+ +QR   V+
Sbjct:  104 KNLQLDYVDLYIIHFPTALKP---GVEIIPTDEHGKAIFDT-VDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSAL-GSHREPEWVDQSAPVLLEDPLIGALAKKHQQTPALIALRYQLQRGIVVL 268          

HSP 2 Score: 75.485 bits (184), Expect = 2.717e-37
Identity = 43/102 (42.16%), Postives = 61/102 (59.80%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSLKKLQLD 359
            + L++G  +P++G G +  +E   S   +    AI  G+RHID A  Y+NE EVG A+    + G VKRED+F T+KLW + H    V  + +DSLK LQLD
Sbjct:    8 VALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLD 109          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: YPR1_YEAST (Putative reductase 1 OS=Saccharomyces cerevisiae GN=YPR1 PE=1 SV=1)

HSP 1 Score: 92.0485 bits (227), Expect = 2.718e-37
Identity = 57/172 (33.14%), Postives = 88/172 (51.16%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSALDA---------DGVLEIDTTI-SLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAY--SKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            Y+DLYL+H+PV  K      TD   D          DG ++IDT   +   TW  M++L   G  +++G+SN+ I   ++ L    +KV P  NQ E HP   +D L+ FC++ GI V A++P G A A          L +  +  +A+K+    AQ+++ W IQR   V+
Sbjct:  105 YVDLYLMHWPVPLK------TDRVTDGNVLCIPTLEDGTVDIDTKEWNFIKTWELMQELPKTGKTKAVGVSNFSINNIKELLESPNNKVVPATNQIEIHPLLPQDELIAFCKEKGIVVEAYSPFGSANA--------PLLKEQAIIDMAKKHGVEPAQLIISWSIQRGYVVL 262          

HSP 2 Score: 84.7297 bits (208), Expect = 2.718e-37
Identity = 44/97 (45.36%), Postives = 60/97 (61.86%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVLEACKDSLKKLQLD 359
            + LN G  +P++G G WR  ++N    +I A+K GYRHID AA Y NE EVG A+ ++     V RE++FITTKLW ++      A   SLK+L LD
Sbjct:   12 LKLNTGASIPVLGFGTWRSVDNNGYHSVIAALKAGYRHIDAAAIYLNEEEVGRAIKDSG----VPREEIFITTKLWGTEQRDPEAALNKSLKRLGLD 104          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1C1_MACFU (Aldo-keto reductase family 1 member C1 homolog OS=Macaca fuscata fuscata GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 104.375 bits (259), Expect = 3.540e-37
Identity = 69/173 (39.88%), Postives = 93/173 (53.76%), Query Frame = 2

Query:  341 KEAPTGYLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVS--CLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            K     Y+DLYL+HFPV+ K    G      D +G L  DT + L  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPY  +  L+ FC+   I + A++ L G+     W    S   L+DPVL  LA+K+KRT A I LR+ +QR   V+
Sbjct:  104 KNLQLDYVDLYLIHFPVSLKP---GEELIPKDENGKLLFDT-VDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSAL-GSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268          

HSP 2 Score: 72.0182 bits (175), Expect = 3.540e-37
Identity = 42/102 (41.18%), Postives = 59/102 (57.84%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVW---RMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSLKKLQLD 359
            + LN+G  MP++G G +    + ++   +    AI+ G+RHID A  Y NE  VG A+    + G VKRED+F T+KLW + H    V  A + SLK LQLD
Sbjct:    8 VKLNDGHFMPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLD 109          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: AK1CN_HORSE (Aldo-keto reductase family 1 member C23 OS=Equus caballus GN=AKR1C23 PE=1 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 4.611e-37
Identity = 68/173 (39.31%), Postives = 91/173 (52.60%), Query Frame = 2

Query:  341 KEAPTGYLDLYLVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVS--CLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            K     Y+DLY++HFPVA K    G      D  G +  DT + L  TW AME     GL +SIG+SN+     ++ L +  L   K KPV NQ E HPY  +  L+ FC+   I + A++ LG       W    S   L+DPVL  +A+KYKRT A I LR+ +QR   V+
Sbjct:  104 KNLQLDYVDLYIIHFPVAVKP---GEEHLPQDEQGRMIFDT-VDLCATWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGL---KHKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAYSALGS--QREHWIDQSSPVLLEDPVLCAMAKKYKRTPALIALRYQLQRGVVVL 267          

HSP 2 Score: 69.3218 bits (168), Expect = 4.611e-37
Identity = 43/102 (42.16%), Postives = 57/102 (55.88%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSD--HGHVLEACKDSLKKLQLD 359
            + LN+G  +  +G G +  +E   S   +   +AI  G+RHIDCA  Y NE EVG A+      G VKRED+F T+KLW +      V  A + SLK LQLD
Sbjct:    8 VELNDGHFIHALGFGTYAPNEVPKSKAVEATKSAIDAGFRHIDCAHLYDNEKEVGLAIRSKIQDGTVKREDIFCTSKLWATSLRLQLVRPALEKSLKNLQLD 109          

BLAST of CK935253 vs. ExPASy Swiss-Prot
Match: GCY_YEAST (Protein GCY OS=Saccharomyces cerevisiae GN=GCY1 PE=1 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 4.613e-37
Identity = 53/166 (31.93%), Postives = 82/166 (49.40%), Query Frame = 2

Query:  359 YLDLYLVHFPVATKHTGVGTTDSA---LDADGVLEID-TTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAY--SKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVANTEWFGTVSCLDDPVLKGLAEKYKRTVAQIVLRWGIQRNTAVI 838
            Y+DLYL+H+P       +   D        DG   +D T  +   TW  M++L   G  +++G+SN+ I   +D LA   +K+ P  NQ E HP   +D L+ FC+  GI V A++PLG   A          L +PV+  +A+K       +V+ W +QR   V+
Sbjct:  105 YVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTDA--------PLLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVL 262          

HSP 2 Score: 87.4261 bits (215), Expect = 4.613e-37
Identity = 44/97 (45.36%), Postives = 64/97 (65.98%), Query Frame = 3

Query:   69 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVLEACKDSLKKLQLD 359
            ++LN G ++P IGLG W+  E++    ++ A+K GYRHID AA YRNE +VG+A+ ++     V RE++F+TTKLW + H     A   SLK+L LD
Sbjct:   12 LSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSG----VPREEIFVTTKLWCTQHHEPEVALDQSLKRLGLD 104