EY756287

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK3_CAEEL (Glycogen synthase kinase-3 OS=Caenorhabditis elegans GN=gsk-3 PE=1 SV=1)

HSP 1 Score: 325.479 bits (833), Expect = 2.605e-88
Identity = 164/252 (65.08%), Postives = 200/252 (79.37%), Query Frame = 3

Query:   15 EIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXX-TVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFKSVYPQK---LWTSSVDFSVLSQTT 758
            E+VAIKKVLQDKR+KNRELQIM+ L+HPNIV LK+ F+S+ +K               TV R+AR+YS+  Q++P+IYVKLY YQ+ R+LAYIH+ IGICHRDIKPQNLL++P +  LKLCDFGSAK LV+ EPNVSYICSRYYRAPELIFGAT YT +ID+WS G VMAELLLGQP+FPG+SGVDQLVEIIKVLGTPTRE+I+ MNPNY EF  PQIK HPW+KVF+   P +   L +  ++++  S+ T
Sbjct:   60 EMVAIKKVLQDKRFKNRELQIMRKLNHPNIVKLKYFFYSSGEKKDELYLNLILEYVPETVYRVARHYSKQRQQIPMIYVKLYMYQLLRSLAYIHS-IGICHRDIKPQNLLIDPESGVLKLCDFGSAKYLVRNEPNVSYICSRYYRAPELIFGATNYTNSIDVWSAGTVMAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIQSMNPNYKEFKFPQIKAHPWNKVFRVHTPAEAIDLISKIIEYTPTSRPT 310          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK3A_RAT (Glycogen synthase kinase-3 alpha OS=Rattus norvegicus GN=Gsk3a PE=1 SV=1)

HSP 1 Score: 322.398 bits (825), Expect = 4.366e-88
Identity = 160/232 (68.97%), Postives = 191/232 (82.33%), Query Frame = 3

Query:   15 EIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXX-TVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFKSVYP 707
            E+VAIKKVLQDKR+KNRELQIM+ LDH NIV L++ F+S+ +K               TV R+AR++++    +P+IYVK+Y YQ+ R+LAYIH+  G+CHRDIKPQNLLV+P T  LKLCDFGSAK LV+GEPNVSYICSRYYRAPELIFGAT+YT++ID+WS GCV+AELLLGQP+FPG+SGVDQLVEIIKVLGTPTRE+I+ MNPNYTEF  PQIK HPW KVFKS  P
Sbjct:  143 ELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLIIPIIYVKVYMYQLFRSLAYIHSQ-GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTP 373          

HSP 2 Score: 23.483 bits (49), Expect = 4.366e-88
Identity = 9/23 (39.13%), Postives = 13/23 (56.52%), Query Frame = 1

Query:  733 IFQYSPKLRCTALGAWVHPFLDE 801
            + +Y+P  R + L A  H F DE
Sbjct:  383 LLEYTPSSRLSPLEACAHSFFDE 405          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK3A_HUMAN (Glycogen synthase kinase-3 alpha OS=Homo sapiens GN=GSK3A PE=1 SV=2)

HSP 1 Score: 322.398 bits (825), Expect = 4.366e-88
Identity = 159/232 (68.53%), Postives = 191/232 (82.33%), Query Frame = 3

Query:   15 EIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXX-TVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFKSVYP 707
            E+VAIKKVLQDKR+KNRELQIM+ LDH NIV L++ F+S+ +K               TV R+AR++++    +P++YVK+Y YQ+ R+LAYIH+  G+CHRDIKPQNLLV+P T  LKLCDFGSAK LV+GEPNVSYICSRYYRAPELIFGAT+YT++ID+WS GCV+AELLLGQP+FPG+SGVDQLVEIIKVLGTPTRE+I+ MNPNYTEF  PQIK HPW KVFKS  P
Sbjct:  143 ELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLTIPILYVKVYMYQLFRSLAYIHSQ-GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKSRTP 373          

HSP 2 Score: 23.483 bits (49), Expect = 4.366e-88
Identity = 9/23 (39.13%), Postives = 13/23 (56.52%), Query Frame = 1

Query:  733 IFQYSPKLRCTALGAWVHPFLDE 801
            + +Y+P  R + L A  H F DE
Sbjct:  383 LLEYTPSSRLSPLEACAHSFFDE 405          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK3A_MOUSE (Glycogen synthase kinase-3 alpha OS=Mus musculus GN=Gsk3a PE=1 SV=2)

HSP 1 Score: 320.472 bits (820), Expect = 1.649e-87
Identity = 158/229 (69.00%), Postives = 189/229 (82.53%), Query Frame = 3

Query:   15 EIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXX-TVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFKS 698
            E+VAIKKVLQDKR+KNRELQIM+ LDH NIV L++ F+S+ +K               TV R+AR++++     P+IY+K+Y YQ+ R+LAYIH+  G+CHRDIKPQNLLV+P T  LKLCDFGSAK LV+GEPNVSYICSRYYRAPELIFGAT+YT++ID+WS GCV+AELLLGQP+FPG+SGVDQLVEIIKVLGTPTRE+I+ MNPNYTEF  PQIK HPW KVFKS
Sbjct:  143 ELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDELYLNLVLEYVPETVYRVARHFTKAKLITPIIYIKVYMYQLFRSLAYIHSQ-GVCHRDIKPQNLLVDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFKS 370          

HSP 2 Score: 23.483 bits (49), Expect = 1.649e-87
Identity = 9/23 (39.13%), Postives = 13/23 (56.52%), Query Frame = 1

Query:  733 IFQYSPKLRCTALGAWVHPFLDE 801
            + +Y+P  R + L A  H F DE
Sbjct:  384 LLEYTPSSRLSPLEACAHSFFDE 406          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: SGG_DROME (Protein kinase shaggy OS=Drosophila melanogaster GN=sgg PE=1 SV=2)

HSP 1 Score: 313.153 bits (801), Expect = 8.090e-87
Identity = 152/229 (66.38%), Postives = 185/229 (80.79%), Query Frame = 3

Query:   12 GEIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXX-TVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFK 695
            GE+VAIKKVLQD+R+KNRELQIM+ L+H NIV L + F+S+ +K               TV ++AR Y++  Q +P+ +++LY YQ+ R+LAYIH+ +GICHRDIKPQNLL++P T  LKLCDFGSAK L+ GEPNVSYICSRYYRAPELIFGA  YTT ID+WS GCV+AELLLGQP+FPG+SGVDQLVE+IKVLGTPTRE+I+ MNPNYTEF  PQIK HPW KVF+
Sbjct:  630 GELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHS-LGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKVFR 857          

HSP 2 Score: 28.4906 bits (62), Expect = 8.090e-87
Identity = 11/23 (47.83%), Postives = 14/23 (60.87%), Query Frame = 1

Query:  733 IFQYSPKLRCTALGAWVHPFLDE 801
            + +Y+P  R T L A  HPF DE
Sbjct:  871 LLEYTPSARITPLKACAHPFFDE 893          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK3_DICDI (Glycogen synthase kinase-3 OS=Dictyostelium discoideum GN=gskA PE=1 SV=2)

HSP 1 Score: 310.842 bits (795), Expect = 2.573e-85
Identity = 151/228 (66.23%), Postives = 185/228 (81.14%), Query Frame = 3

Query:   15 EIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXXTVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFKS 698
            E+VAIKKVLQD+RYKNRELQIM+ML+H NIV+LK+ F+ T+D               TV R++R+YS   Q +P I+VKLY YQ+CR++ YIH+ +GICHRDIKPQNLL++  T  LKLCDFGSAK+L+KGE NVSYICSR+YRAPELIFG+T YTT ID+WS GCV+AELLLGQPLFPGE+G+DQLVEIIKVLGTPT+E+I  MNP YT F  P+IK +PW +VFK+
Sbjct:   80 EVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFY-TSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHS-LGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKA 305          

HSP 2 Score: 25.7942 bits (55), Expect = 2.573e-85
Identity = 11/27 (40.74%), Postives = 12/27 (44.44%), Query Frame = 1

Query:  733 IFQYSPKLRCTALGAWVHPFLDEXXDP 813
            I  Y P  R   +    HPF DE  DP
Sbjct:  319 ILLYDPSSRLKPVEICAHPFFDELRDP 345          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK3H_DROME (Putative glycogen synthase kinase-3 homolog OS=Drosophila melanogaster GN=gskt PE=2 SV=1)

HSP 1 Score: 292.352 bits (747), Expect = 1.975e-79
Identity = 138/228 (60.53%), Postives = 179/228 (78.51%), Query Frame = 3

Query:   15 EIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXX-TVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFK 695
            E+VAIKKVLQD+R+KNRELQIM+ L H NI+ LK  FFS+ +K               T+ ++ R Y+R  Q +P+ +V+LY YQ+ R++ Y+H+ +G CHRDIKPQN+L++  T  LKLCDFGSAK L+ GEPNVSYICSRYYRAPELIFG+T+YTT ID+WS GCVM+ELLLGQ +FPG+SGVDQ+VEI+KV+GTPT E++  MNP+Y +F LP++KPHPW KVF+
Sbjct:   57 EMVAIKKVLQDRRFKNRELQIMRKLRHDNIITLKWFFFSSGEKRDEVYLNLVMEFLPETLYKVERQYARAKQTLPVNFVRLYMYQLLRSMGYLHS-LGFCHRDIKPQNMLLDSETGVLKLCDFGSAKQLISGEPNVSYICSRYYRAPELIFGSTDYTTKIDMWSAGCVMSELLLGQLIFPGDSGVDQIVEIVKVMGTPTSEQLHDMNPHYKQFKLPELKPHPWSKVFR 283          

HSP 2 Score: 24.6386 bits (52), Expect = 1.975e-79
Identity = 10/20 (50.00%), Postives = 11/20 (55.00%), Query Frame = 1

Query:  742 YSPKLRCTALGAWVHPFLDE 801
            YSP  R + L    HPF DE
Sbjct:  300 YSPNARVSPLMGCAHPFFDE 319          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK3_SCHPO (Protein kinase gsk3 OS=Schizosaccharomyces pombe GN=gsk3 PE=1 SV=3)

HSP 1 Score: 295.819 bits (756), Expect = 2.211e-79
Identity = 149/229 (65.07%), Postives = 175/229 (76.42%), Query Frame = 3

Query:   24 AIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXX-TVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFKSVYP 707
            AIK+VLQDKR+KNRELQIM+++ HPNIV L   +++T D                T+ R +R Y+R    MP++ VKLY YQ+ R+LAYIH   GICHRDIKPQNLL++P    LKLCDFGSAK+LV GEPNVSYICSRYYRAPELIFGAT+YT AIDIWSTGCVMAEL+LG PLFPGESG+DQLVEIIK+LGTP+RE+IK MNPNY E   PQI+P P  +VF    P
Sbjct:   59 AIKRVLQDKRFKNRELQIMRIMKHPNIVDLIAYYYTTGDNSDEVYLNLVLEFMPETIYRASRLYTRQKLSMPMLEVKLYIYQLLRSLAYIH-ASGICHRDIKPQNLLLDPENGILKLCDFGSAKILVAGEPNVSYICSRYYRAPELIFGATDYTHAIDIWSTGCVMAELMLGHPLFPGESGIDQLVEIIKILGTPSREQIKTMNPNYMEHRFPQIRPQPLSRVFSRSVP 286          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: MDS1_YEAST (Serine/threonine-protein kinase MDS1/RIM11 OS=Saccharomyces cerevisiae GN=MDS1 PE=1 SV=1)

HSP 1 Score: 278.87 bits (712), Expect = 2.797e-74
Identity = 139/229 (60.70%), Postives = 171/229 (74.67%), Query Frame = 3

Query:   15 EIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTDKXXXXXXXXXXXXXXTVNRIARNYSRIHQRMPL--IYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFK 695
            E VAIKKVLQDKR+KNREL+IM+ML H NI+ LK+ F+    +              ++ +  R++  +HQR P+  + +K Y +Q+ ++L Y+H+   +CHRDIKPQNLLV+P T  LKLCDFGSAK L   EPNVSYICSRYYRAPELIFGAT YT  IDIWS+GCVMAELLLGQP+FPGESG+DQLVEIIK+LGTP+++EI  MNPNY E   PQIKP P  +VFK
Sbjct:   63 EKVAIKKVLQDKRFKNRELEIMKMLSHINIIDLKYFFYERDSQDEIYLNLILEYMPQSLYQRLRHF--VHQRTPMSRLEIKYYMFQLFKSLNYLHHFANVCHRDIKPQNLLVDPETWSLKLCDFGSAKQLKPTEPNVSYICSRYYRAPELIFGATNYTNQIDIWSSGCVMAELLLGQPMFPGESGIDQLVEIIKILGTPSKQEICSMNPNYMEHKFPQIKPIPLSRVFK 289          

BLAST of EY756287 vs. ExPASy Swiss-Prot
Match: GSK31_SCHPO (Protein kinase gsk31 OS=Schizosaccharomyces pombe GN=gsk31 PE=1 SV=1)

HSP 1 Score: 262.307 bits (669), Expect = 2.351e-71
Identity = 138/244 (56.56%), Postives = 171/244 (70.08%), Query Frame = 3

Query:    9 PGEIVAIKKVLQDKRYKNRELQIMQMLDHPNIVALKHCFFSTTD--KXXXXXXXXXXXXXXTVNRIARNYSRIHQRMPLIYVKLYTYQICRALAYIHNCIGICHRDIKPQNLLVNPHTHQLKLCDFGSAKVLVKGEPNVSYICSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEF*LPQIKPHPWHKVFKSVYPQKLWTSSVD 734
            PG  +A+K+VLQDKRYKNRELQIM+ + HPNI+ L   FF T +  K              TV    R Y+R  + +P + +KLY +Q+ RALAY+H+  G+CHRDIKPQNLLV+  T  LKLCDFGSAKVLV  EPNVSYICSRYYRAPEL+FGAT YTT ID+WS  CV+AEL +G+PLFPG+S V+QLVEII+VLGTP+  EI  MNPNY    LP ++PH      +SV P     +++D
Sbjct:   48 PG-FIAVKRVLQDKRYKNRELQIMRAISHPNIIKLI-AFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYAFQLFRALAYLHST-GVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPNVSYICSRYYRAPELVFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMNPNYVNHSLPNVRPH----TLESVMPHNCTKNAMD 284          

HSP 2 Score: 27.7202 bits (60), Expect = 2.351e-71
Identity = 11/24 (45.83%), Postives = 13/24 (54.17%), Query Frame = 1

Query:  742 YSPKLRCTALGAWVHPFLDEXXDP 813
            Y P  R +A+    HPF DE  DP
Sbjct:  292 YVPSKRISAIEVLTHPFFDELRDP 315