EY756177

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: CHK1_CHICK (Serine/threonine-protein kinase Chk1 OS=Gallus gallus GN=CHEK1 PE=1 SV=1)

HSP 1 Score: 72.4034 bits (176), Expect = 3.954e-12
Identity = 50/173 (28.90%), Postives = 81/173 (46.82%), Query Frame = 3

Query:    9 PEDFYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDN 527
            PE+  +E+ +     H N++   GH      + L  +Y   G L  ++   +    P +   RF   L    G+ +LH      I H +LKP N+LLD+  N +ISDFGLA +     +  + N+    L YVAPEL  +     E  D++  GV++  ++ G  P +   D+
Sbjct:   49 PENIKKEICINKMLNHENVVKFYGHRREGATQYLFLEYCSGGELFDRIEPDIGMPEPEA--QRFFQQL--IAGVVYLHSM---GITHRDLKPENLLLDERDNLKISDFGLATVFKHNGRERLLNKMCGTLPYVAPELLRRPEFRAEPVDVWACGVVLTAMLAGELPWDQPSDS 214          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: AIR2_CAEEL (Aurora/Ipl1-related protein kinase 2 OS=Caenorhabditis elegans GN=air-2 PE=1 SV=2)

HSP 1 Score: 72.4034 bits (176), Expect = 3.954e-12
Identity = 47/171 (27.49%), Postives = 83/171 (48.54%), Query Frame = 3

Query:   24 REVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALG---YVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDN 527
            RE+ +     HPN+I L  ++W  +   LV +YAP G    +++++L  +   S     K +   A  L++ H   R  +IH ++KP N+L+      +I DFG +        H  SN+ Q+  G   Y+ PE+       ++  D++  GVL  E + G+ P E+ + +
Sbjct:   77 REIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGG----EMYKQLTVSKRFSEPTAAKYMYEIADALSYCH---RKNVIHRDIKPENLLIGSQGELKIGDFGWS-------VHAPSNKRQTMCGTMDYLPPEMV-NGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQS 232          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: Y9866_DICDI (Probable serine/threonine-protein kinase DDB_G0271402 OS=Dictyostelium discoideum GN=DDB_G0271402 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 71/278 (25.54%), Postives = 119/278 (42.81%), Query Frame = 3

Query:   24 REVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSL-------------QAKLHERL----PSTPPLS--------------WTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALG---YVAPELTCQSLRVNEKCDIYGFGVLILELVT------GRRP--VEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQILQVIKTPL 731
            REV +L +  HPNL+  +G         +V+++   G L             +  +H ++     STP LS              W  R K+    A  +A+LH      +IH +LK +N+L+ DN+  ++ D G AR   ++     + R  +  G    +APE+       NE CD++ +G+++ E++T        RP  ++YG D                     VD  +   P+D   P LKL L CT + P +RP+  E+ + L+ +   L
Sbjct:   82 REVAML-RFSHPNLVQFIGVSERGSSLYIVTEFVQGGDLAYYLFRNKFDDTPEQYIHRKVNVGSSSTPDLSDPTVHNGEKLVQLAWPLRIKIAYDVACAMAYLHSR---NVIHRDLKSTNLLVGDNWRIKVCDMGFAR-TAQVGGGSRAKRTMTICGTTNCMAPEVVL-GQDYNEACDVFSYGIVLSEIITRMDTTNNLRPSSLKYGLD---------------------VDVLLPLVPKDCPPPFLKLVLDCTEYDPDNRPTFKEITERLKSLTKKL 332          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: Y9849_DICDI (Probable serine/threonine-protein kinase DDB_G0278535 OS=Dictyostelium discoideum GN=DDB_G0278535 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 57/238 (23.95%), Postives = 109/238 (45.80%), Query Frame = 3

Query:   12 EDFYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTC-QSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQILQVIK 722
            E+F +E +++G  R   +++  G    P+L  +V +Y    SL    H        + W   F+  +    G+  LH+ + P I+H + K  N+L+++++  ++SDFGL+R  T  +   +S + +    Y +PE+          K DIY  G++  ELVT     EY        SE+  + ++   +L+  +      P++    +  L   C     + RPS  E+++ L  ++
Sbjct:  568 EEFKKEFQIMGSIRSQFMVTFYGACIEPKL-CMVMEYCSRDSLY---HVMNTKKYDIGWDRFFQFTMQMTLGVQCLHN-WTPQIVHRDFKSLNLLVNEDWECKVSDFGLSRFNTADNLETLS-KIRGTFAYCSPEVAVGNGSLYTTKSDIYSIGIVFWELVTRVINGEYSRP----YSEYSHIKMDFQIMLNSKEGLRPTLPQNTPPGLEALYKQCVNQEQTLRPSCEEIIETLNRLR 795          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: Y9847_DICDI (Probable serine/threonine-protein kinase DDB_G0267686 OS=Dictyostelium discoideum GN=DDB_G0267686 PE=3 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 45/158 (28.48%), Postives = 82/158 (51.90%), Query Frame = 3

Query:   15 DFYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILEL 488
            DF +E+ ++   R P+++   G    P++  ++ +Y  N +L   +H ++  T    W   FK  +   +G+  LH S++P I+H +LK  N+L+ DN+  +++DFGL+R  T   K   +   +    Y APE+         K DI+  G+++ EL
Sbjct: 1989 DFLKELEIMSSLRSPHVVYFYGMVLDPKI-CMIMEYCSNQTLYHLMHLQMNFT----WDWVFKFAIEMVRGVNCLH-SWKPVIVHRDLKSLNLLVSDNWTIKVADFGLSRFATA--KSASNRTTRGTFAYCAPEVFYGI--HTTKGDIFSIGIILWEL 2136          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: RAF1_XENLA (RAF proto-oncogene serine/threonine-protein kinase OS=Xenopus laevis GN=raf1 PE=2 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 59/246 (23.98%), Postives = 111/246 (45.12%), Query Frame = 3

Query:   18 FYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNE------KCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQILQVIKTPLPQ 737
            F  EV VL K RH N++  +G Y T     +V+ +    SL   LH                +   TA+G+ +LH      IIH ++K +NI L +    +I DFGLA + TR        +   ++ ++APE+    +R+ +      + D+Y +G+++ EL+TG  P  +  D      + +  L+  G V+    P +    ++    + +L       +   RP   +++  +++++  LP+
Sbjct:  381 FRNEVAVLRKTRHVNILLFMG-YMTKDNLAIVTQWCEGSSLYYHLHVL---DTKFQMFQLIDIARQTAQGMDYLHAK---NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKTRWSGSQQVEQLTGSILWMAPEV----IRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHIRDR-----DQIIFLVGRGGVV----PDLSKLYKNCPKAMKRLVADSIKKLRDERPLFPQILSSIELLQHSLPK 606          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: M3K9_HUMAN (Mitogen-activated protein kinase kinase kinase 9 OS=Homo sapiens GN=MAP3K9 PE=1 SV=3)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 73/246 (29.67%), Postives = 112/246 (45.53%), Query Frame = 3

Query:   12 EDFYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLH-ERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILL--------DDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQILQVIK 722
            E+  +E ++    +HPN+I+L G         LV ++A  G L   L  +R+P    ++W  +       A+G+ +LH     PIIH +LK SNIL+          N   +I+DFGLAR   R  K   +  +     ++APE+   S+  ++  D++ +GVL+ EL+TG  P   G D + +            N L    PS    PE    P  KL   C    P SRPS   ++  L  I+
Sbjct:  186 ENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQI------ARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTY----AWMAPEVIRASM-FSKGSDVWSYGVLLWELLTGEVPFR-GIDGLAVAYGVAM------NKLALPIPS--TCPE----PFAKLMEDCWNPDPHSRPSFTNILDQLTTIE 407          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: M3K12_RAT (Mitogen-activated protein kinase kinase kinase 12 OS=Rattus norvegicus GN=Map3k12 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 53/172 (30.81%), Postives = 91/172 (52.91%), Query Frame = 3

Query:   27 EVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPL--SWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVI 536
            +++ L K +HPN+I+  G         ++ ++   G L   L    P TP L   W+      +G A G+ +LH      IIH +LK  N+L+  +   +ISDFG ++ L+  DK    + F   + ++APE+  ++  V+EK DI+ FGV++ EL+TG  P +  + + +I
Sbjct:  194 DIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWS------MGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKELS--DKSTKMS-FAGTVAWMAPEVI-RNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAII 352          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: M3K12_MOUSE (Mitogen-activated protein kinase kinase kinase 12 OS=Mus musculus GN=Map3k12 PE=1 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 53/172 (30.81%), Postives = 91/172 (52.91%), Query Frame = 3

Query:   27 EVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPL--SWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVI 536
            +++ L K +HPN+I+  G         ++ ++   G L   L    P TP L   W+      +G A G+ +LH      IIH +LK  N+L+  +   +ISDFG ++ L+  DK    + F   + ++APE+  ++  V+EK DI+ FGV++ EL+TG  P +  + + +I
Sbjct:  194 DIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWS------MGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKELS--DKSTKMS-FAGTVAWMAPEVI-RNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAII 352          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: M3K12_HUMAN (Mitogen-activated protein kinase kinase kinase 12 OS=Homo sapiens GN=MAP3K12 PE=1 SV=2)

HSP 1 Score: 72.0182 bits (175), Expect = 5.164e-12
Identity = 53/172 (30.81%), Postives = 91/172 (52.91%), Query Frame = 3

Query:   27 EVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPL--SWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVI 536
            +++ L K +HPN+I+  G         ++ ++   G L   L    P TP L   W+      +G A G+ +LH      IIH +LK  N+L+  +   +ISDFG ++ L+  DK    + F   + ++APE+  ++  V+EK DI+ FGV++ EL+TG  P +  + + +I
Sbjct:  161 DIKHLRKLKHPNIITFKGVCTQAPCYCILMEFCAQGQLYEVLRAGRPVTPSLLVDWS------MGIAGGMNYLHLH---KIIHRDLKSPNMLITYDDVVKISDFGTSKELS--DKSTKMS-FAGTVAWMAPEVI-RNEPVSEKVDIWSFGVVLWELLTGEIPYKDVDSSAII 319