EY756177

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: ACK1_HUMAN (Activated CDC42 kinase 1 OS=Homo sapiens GN=TNK2 PE=1 SV=3)

HSP 1 Score: 70.8626 bits (172), Expect = 1.150e-11
Identity = 70/236 (29.66%), Postives = 109/236 (46.19%), Query Frame = 3

Query:   12 EDFYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKH-VMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVIL--SEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQIL 710
            +DF REV  +    H NLI L G   TP +K +V++ AP GSL  +L +       L   +R+ V    A+G+ +L        IH +L   N+LL      +I DFGL R L + D H VM    +    + APE + ++   +   D + FGV + E+ T      YG++  + L  S+ +  + +EG  L    P   D P+D    +  + + C  H P  RP+   +   L
Sbjct:  172 DDFIREVNAMHSLDHRNLIRLYGVVLTPPMK-MVTELAPLGSLLDRLRKH-QGHFLLGTLSRYAV--QVAEGMGYLESK---RFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPE-SLKTRTFSHASDTWMFGVTLWEMFT------YGQEPWIGLNGSQILHKIDKEGERL----PRPEDCPQD----IYNVMVQCWAHKPEDRPTFVALRDFL 385          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: SNF1_SCHPO (SNF1-like protein kinase ssp2 OS=Schizosaccharomyces pombe GN=ssp2 PE=1 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 52/163 (31.90%), Postives = 81/163 (49.69%), Query Frame = 3

Query:   24 REVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVE 512
            RE+  L   RHP++I L     TP   ++V +YA  G L   + E+   T       RF   +  A    H H      I+H +LKP N+LLDDN N +I+DFGL+ ++T  D + +     S   Y APE+    L    + D++  G+++  ++ GR P +
Sbjct:   81 REISYLKLLRHPHIIKLYDVITTPTDIVMVIEYA-GGELFDYIVEKKRMTEDEG--RRFFQQIICAIEYCHRHK-----IVHRDLKPENLLLDDNLNVKIADFGLSNIMT--DGNFLKTSCGSP-NYAAPEVINGKLYAGPEVDVWSCGIVLYVMLVGRLPFD 232          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: RIPK1_MOUSE (Receptor-interacting serine/threonine-protein kinase 1 OS=Mus musculus GN=Ripk1 PE=1 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 64/238 (26.89%), Postives = 110/238 (46.22%), Query Frame = 3

Query:   12 EDFYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLT---------RLDKHVMSNRFQS---ALGYVAPE-LTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPS 686
            E    E +++ + RH  ++ L+G         LV +Y   G+L   L  ++    PLS   R  +I+   +G+ +LH      +IH +LKP NIL+D +++ +I+D G+A   T            K V S   ++    L Y+APE L   + +  EK D+Y FG+++  +   + P E      VI +E   + ++ GN      P++ +  E     ++ L   C   IP  RP+
Sbjct:   58 EVLLEEGKMMHRLRHSRVVKLLGIIIEEGNYSLVMEYMEKGNLMHVLKTQIDV--PLSLKGR--IIVEAIEGMCYLHDK---GVIHKDLKPENILVDRDFHIKIADLGVASFKTWSKLTKEKDNKQKEVSSTTKKNNGGTLYYMAPEHLNDINAKPTEKSDVYSFGIVLWAIFAKKEPYEN-----VICTEQFVICIKSGN-----RPNVEEILEYCPREIISLMERCWQAIPEDRPT 278          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: RAF1_PONAB (RAF proto-oncogene serine/threonine-protein kinase OS=Pongo abelii GN=RAF1 PE=2 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 56/246 (22.76%), Postives = 111/246 (45.12%), Query Frame = 3

Query:   18 FYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNE------KCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQILQVIKTPLPQ 737
            F  EV VL K RH N++  +G Y T     +V+ +    SL   LH +              +   TA+G+ +LH      IIH ++K +NI L +    +I DFGLA + +R        +   ++ ++APE+    +R+ +      + D+Y +G+++ EL+TG  P  +       ++   +++   G       P +    ++    + +L   C   +   RP   +++  +++++  LP+
Sbjct:  390 FRNEVAVLRKTRHVNILLFMG-YMTKDNLAIVTQWCEGSSLYKHLHVQ---ETKFQMFQLIDIARQTAQGMDYLHAK---NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEV----IRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSH-------INNRDQIIFMVGR--GYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPK 615          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: RAF1_HUMAN (RAF proto-oncogene serine/threonine-protein kinase OS=Homo sapiens GN=RAF1 PE=1 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 56/246 (22.76%), Postives = 111/246 (45.12%), Query Frame = 3

Query:   18 FYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNE------KCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQILQVIKTPLPQ 737
            F  EV VL K RH N++  +G Y T     +V+ +    SL   LH +              +   TA+G+ +LH      IIH ++K +NI L +    +I DFGLA + +R        +   ++ ++APE+    +R+ +      + D+Y +G+++ EL+TG  P  +       ++   +++   G       P +    ++    + +L   C   +   RP   +++  +++++  LP+
Sbjct:  390 FRNEVAVLRKTRHVNILLFMG-YMTKDNLAIVTQWCEGSSLYKHLHVQ---ETKFQMFQLIDIARQTAQGMDYLHAK---NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEV----IRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSH-------INNRDQIIFMVGR--GYASPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPK 615          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: RAF1_CHICK (RAF proto-oncogene serine/threonine-protein kinase OS=Gallus gallus GN=RAF1 PE=2 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 56/242 (23.14%), Postives = 109/242 (45.04%), Query Frame = 3

Query:   18 FYREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPEL--TCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCVDPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQILQVIKTPLPQ 737
            F  EV VL K RH N++  +G Y T     +V+ +    SL   LH +              +   TA+G+ +LH      IIH ++K +NI L +    +I DFGLA + +R        +   ++ ++APE+     S   + + D+Y +G+++ EL+TG  P  +       ++   +++   G       P +    ++    + +L   C   +   RP   +++  +++++  LP+
Sbjct:  390 FRNEVAVLRKTRHVNILLFMG-YMTKDNLAIVTQWCEGSSLYKHLHVQ---ETKFQMFQLIDIARQTAQGMDYLHAK---NIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSILWMAPEVIRMQDSNPFSFQSDVYSYGIVLYELMTGELPYSH-------INNRDQIIFMVGR--GYASPDLSKLYKNCPKAMKRLVADCLKKVREERPLFPQILSSIELLQHSLPK 615          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: MPKC_ASPNC (Mitogen-activated protein kinase mpkC OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=mpkC PE=3 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 55/170 (32.35%), Postives = 88/170 (51.76%), Query Frame = 3

Query:   21 YREVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNV 530
            YREV++L   RH NLI L   + +P    L   Y     L   L+ RL ++ PL             +GL ++H +    +IH +LKPSNIL+++N + +I DFGLARL        +S R+     Y APE+     +   + DI+  G ++ E++ G +P+  G+D++
Sbjct:   65 YREVKLLKHLRHENLIGLSDIFISP----LEDVYLVTDLLGTDLN-RLLTSKPLDGKFVQYFTYQLLRGLKYIHSA---GVIHRDLKPSNILINENCDLKICDFGLARLQEPQMTGYVSTRY-----YRAPEIMLTWQKYGMQVDIWSAGCIVAEMLRG-KPLFPGKDHI 220          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: MPK1_ORYSJ (Mitogen-activated protein kinase 1 OS=Oryza sativa subsp. japonica GN=MPK1 PE=1 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 51/181 (28.18%), Postives = 87/181 (48.07%), Query Frame = 3

Query:   24 REVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLE 566
            RE+++L    H N++++      PQ       Y     +   LH+ + S   LS  +    +    +GL ++H +    ++H +LKPSN+LL+ N + +I DFGLAR  +  D       +     Y APEL   S       D++  G + +EL+  R+P+  G D+V      +R+L+E
Sbjct:  113 REIKLLRHMDHENIVAIRDIIPPPQRNSFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSA---NVLHRDLKPSNLLLNANCDLKICDFGLARTTSETD---FMTEYVVTRWYRAPELLLNSSEYTAAIDVWSVGCIFMELM-DRKPLFPGRDHV----HQLRLLME 282          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: MAPK_PEA (Mitogen-activated protein kinase homolog D5 OS=Pisum sativum PE=2 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 50/181 (27.62%), Postives = 90/181 (49.72%), Query Frame = 3

Query:   24 REVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYNPRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILELVTGRRPVEYGEDNVVILSEHVRVLLE 566
            RE++++    H N++++      PQ ++    Y     +   LH+ + S   LS  +    +    +GL ++H +    ++H +LKPSN+LL+ N + +I DFGLAR+ +  D       +     Y APEL   S       D++  G + +EL+  R+P+  G D+V      +R+L+E
Sbjct:  108 REIKLVRHMDHENVVAIRDIVPPPQREVFNDVYIAYELMDTDLHQIIRSNQALSEEHCQYFLYQILRGLKYIHSA---NVLHRDLKPSNLLLNANCDLKICDFGLARVTSETD---FMTEYVVTRWYRAPELLLNSSDYTAAIDVWSVGCIFMELM-DRKPLFPGRDHV----HQLRLLME 277          

BLAST of EY756177 vs. ExPASy Swiss-Prot
Match: LRRK2_MOUSE (Leucine-rich repeat serine/threonine-protein kinase 2 OS=Mus musculus GN=Lrrk2 PE=2 SV=1)

HSP 1 Score: 70.4774 bits (171), Expect = 1.502e-11
Identity = 70/236 (29.66%), Postives = 113/236 (47.88%), Query Frame = 3

Query:   24 REVRVLGKARHPNLISLVGHYWTPQLKLLVSDYAPNGSLQAKLHERLPSTPPLSWTNRFKVILGTAKGLAHLHHSFRPPIIHYNLKPSNILLDDNYN-----PRISDFGLARLLTRLDKHVMSNRFQSALGYVAPELTCQSLRVNEKCDIYGFGVLILEL-VTGRRPVEYGEDNVVILSEHVRVLLEEGNVLDCV-DPSMGDYPEDEVLPVLKLALVCTCHIPSSRPSMAEVVQIL 710
            +E+ VL    HP+LISL+     P  ++LV + A  GSL   L +   S   L+ T + ++ L  A GL +LH +    II+ +LKP N+LL   Y       +I+D+G+A+   R+         +   G+ APE+   ++  N++ D+Y FG+L+ ++  TG R +E      +        L  +G + D V +     +P  E     KL   C    P  RP+ A+V  IL
Sbjct: 1919 QELVVLCHLHHPSLISLLAAGIRP--RMLVMELASKGSLDRLLQQDKAS---LTRTLQHRIALHVADGLRYLHSAM---IIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTS----EGTPGFRAPEVARGNVIYNQQADVYSFGLLLHDIWTTGSRIME-----GLRFPNEFDELAIQGKLPDPVKEYGCAPWPMVE-----KLITKCLKENPQERPTSAQVFDIL 2132