EY756166

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: TIE1_BOVIN (Tyrosine-protein kinase receptor Tie-1 OS=Bos taurus GN=TIE1 PE=2 SV=1)

HSP 1 Score: 53.9138 bits (128), Expect = 3.904e-12
Identity = 31/88 (35.23%), Postives = 49/88 (55.68%), Query Frame = 3

Query:  318 ESLLGEGGFGRVYKGYL--ESINQVVAIKQLDRNGVQGN-REFLVEVLMLSLL-HHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHL 569
            E L+GEG FG+V +  +  + +    AIK L     + + R+F  E+ +L  L HHPN++NL+G C +     +  EY P G++ D L
Sbjct:  840 EDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACENRGYLYIAIEYAPYGNLLDFL 927          

HSP 2 Score: 38.5058 bits (88), Expect = 3.904e-12
Identity = 18/49 (36.73%), Postives = 31/49 (63.27%), Query Frame = 1

Query:  634 MKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAK 780
            ++ A+ AA G++YL +K     I+RDL   N+L+      K++DFGL++
Sbjct:  955 LRFASDAANGMQYLSEKQ---FIHRDLAARNVLVGENLASKIADFGLSR 1000          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: TIE1_MOUSE (Tyrosine-protein kinase receptor Tie-1 OS=Mus musculus GN=Tie1 PE=2 SV=2)

HSP 1 Score: 53.9138 bits (128), Expect = 3.905e-12
Identity = 31/88 (35.23%), Postives = 49/88 (55.68%), Query Frame = 3

Query:  318 ESLLGEGGFGRVYKGYL--ESINQVVAIKQLDRNGVQGN-REFLVEVLMLSLL-HHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHL 569
            E L+GEG FG+V +  +  + +    AIK L     + + R+F  E+ +L  L HHPN++NL+G C +     +  EY P G++ D L
Sbjct:  838 EDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACENRGYLYIAIEYAPYGNLLDFL 925          

HSP 2 Score: 38.5058 bits (88), Expect = 3.905e-12
Identity = 18/49 (36.73%), Postives = 31/49 (63.27%), Query Frame = 1

Query:  634 MKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAK 780
            ++ A+ AA G++YL +K     I+RDL   N+L+      K++DFGL++
Sbjct:  953 LRFASDAANGMQYLSEKQ---FIHRDLAARNVLVGENLASKIADFGLSR 998          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: Y9871_DICDI (Probable serine/threonine-protein kinase DDB_G0271682 OS=Dictyostelium discoideum GN=DDB_G0271682 PE=3 SV=2)

HSP 1 Score: 54.6842 bits (130), Expect = 3.915e-12
Identity = 24/60 (40.00%), Postives = 41/60 (68.33%), Query Frame = 1

Query:  607 KKPLDWNTRMKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAKLV 786
            K  L  + ++K+    A+G+ YLH  + PP+I+RDLK  N+L+D  ++ K+SDFGL++ +
Sbjct:  451 KSELSLSVKVKMLIDVAQGMNYLHTYS-PPIIHRDLKSLNLLVDNNFNVKVSDFGLSRFI 509          

HSP 2 Score: 37.7354 bits (86), Expect = 3.915e-12
Identity = 26/83 (31.33%), Postives = 43/83 (51.81%), Query Frame = 3

Query:  327 LGEGGFGRVYKGYLESINQVVAIKQLDRNGVQGNR--EFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHL 569
            +G G  G V +   E     VA+K + ++ ++ ++  EF  EV +L  L HPN+V  +G C       ++ EY+  GS+ D L
Sbjct:  366 IGSGACGEVCQ--YEWKGTPVAVKTIFKSLLRKDKKEEFEKEVSILKCLRHPNVVLFMGTCLLNGNLAIITEYLNRGSLRDVL 446          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: TIE2_HUMAN (Angiopoietin-1 receptor OS=Homo sapiens GN=TEK PE=1 SV=2)

HSP 1 Score: 50.8322 bits (120), Expect = 5.070e-12
Identity = 30/92 (32.61%), Postives = 51/92 (55.43%), Query Frame = 3

Query:  306 NFRSESLLGEGGFGRVYKGYL--ESINQVVAIKQLDRNGVQGN-REFLVEVLMLSLL-HHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHL 569
            + + + ++GEG FG+V K  +  + +    AIK++     + + R+F  E+ +L  L HHPN++NL+G C       L  EY P G++ D L
Sbjct:  823 DIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFL 914          

HSP 2 Score: 41.2022 bits (95), Expect = 5.070e-12
Identity = 21/49 (42.86%), Postives = 30/49 (61.22%), Query Frame = 1

Query:  634 MKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAK 780
            +  AA  ARG++YL  K     I+RDL   NIL+   Y  K++DFGL++
Sbjct:  942 LHFAADVARGMDYLSQKQ---FIHRDLAARNILVGENYVAKIADFGLSR 987          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: TIE2_BOVIN (Angiopoietin-1 receptor OS=Bos taurus GN=TEK PE=2 SV=1)

HSP 1 Score: 50.8322 bits (120), Expect = 5.070e-12
Identity = 30/92 (32.61%), Postives = 51/92 (55.43%), Query Frame = 3

Query:  306 NFRSESLLGEGGFGRVYKGYL--ESINQVVAIKQLDRNGVQGN-REFLVEVLMLSLL-HHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHL 569
            + + + ++GEG FG+V K  +  + +    AIK++     + + R+F  E+ +L  L HHPN++NL+G C       L  EY P G++ D L
Sbjct:  824 DIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFL 915          

HSP 2 Score: 41.2022 bits (95), Expect = 5.070e-12
Identity = 21/49 (42.86%), Postives = 30/49 (61.22%), Query Frame = 1

Query:  634 MKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAK 780
            +  AA  ARG++YL  K     I+RDL   NIL+   Y  K++DFGL++
Sbjct:  943 LHFAADVARGMDYLSQKQ---FIHRDLAARNILVGENYVAKIADFGLSR 988          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: TIE2_MOUSE (Angiopoietin-1 receptor OS=Mus musculus GN=Tek PE=1 SV=2)

HSP 1 Score: 50.8322 bits (120), Expect = 5.071e-12
Identity = 30/92 (32.61%), Postives = 51/92 (55.43%), Query Frame = 3

Query:  306 NFRSESLLGEGGFGRVYKGYL--ESINQVVAIKQLDRNGVQGN-REFLVEVLMLSLL-HHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHL 569
            + + + ++GEG FG+V K  +  + +    AIK++     + + R+F  E+ +L  L HHPN++NL+G C       L  EY P G++ D L
Sbjct:  821 DIKFQDVIGEGNFGQVLKARIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAIEYAPHGNLLDFL 912          

HSP 2 Score: 41.2022 bits (95), Expect = 5.071e-12
Identity = 21/49 (42.86%), Postives = 30/49 (61.22%), Query Frame = 1

Query:  634 MKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAK 780
            +  AA  ARG++YL  K     I+RDL   NIL+   Y  K++DFGL++
Sbjct:  940 LHFAADVARGMDYLSQKQ---FIHRDLAARNILVGENYIAKIADFGLSR 985          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: M3K7_RAT (Mitogen-activated protein kinase kinase kinase 7 OS=Rattus norvegicus GN=Map3k7 PE=2 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 6.690e-12
Identity = 44/126 (34.92%), Postives = 66/126 (52.38%), Query Frame = 3

Query:  204 MNSSLRVKEASEDGASDQITA--QTLTFRELAAATKNFRSESLLGEGGFGRVYKGYLESINQVVAIKQLDRNGVQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHLHG 575
            M+++     +S   AS+ I A  Q L F E+    K    E ++G G FG V K    + +  VAIKQ++    +  + F+VE+  LS ++HPN+V L G C   +   LV EY   GS+ + LHG
Sbjct:    1 MSTASAASSSSSSSASEMIEAPSQVLNFEEIDY--KEIEVEEVVGRGAFGVVCKAKWRAKD--VAIKQIESESER--KAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLYNVLHG 118          

HSP 2 Score: 33.8834 bits (76), Expect = 6.690e-12
Identity = 23/62 (37.10%), Postives = 32/62 (51.61%), Query Frame = 1

Query:  604 GKKPLDWNTR---MKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHP-KLSDFGLA 777
            G +PL + T    M      ++G+ YLH      +I+RDLK  N+LL  G    K+ DFG A
Sbjct:  118 GAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTA 179          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: M3K7_MOUSE (Mitogen-activated protein kinase kinase kinase 7 OS=Mus musculus GN=Map3k7 PE=1 SV=1)

HSP 1 Score: 57.7658 bits (138), Expect = 6.699e-12
Identity = 44/126 (34.92%), Postives = 66/126 (52.38%), Query Frame = 3

Query:  204 MNSSLRVKEASEDGASDQITA--QTLTFRELAAATKNFRSESLLGEGGFGRVYKGYLESINQVVAIKQLDRNGVQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHLHG 575
            M+++     +S   AS+ I A  Q L F E+    K    E ++G G FG V K    + +  VAIKQ++    +  + F+VE+  LS ++HPN+V L G C   +   LV EY   GS+ + LHG
Sbjct:    1 MSTASAASSSSSSSASEMIEAPSQVLNFEEIDY--KEIEVEEVVGRGAFGVVCKAKWRAKD--VAIKQIESESER--KAFIVELRQLSRVNHPNIVKLYGACL--NPVCLVMEYAEGGSLYNVLHG 118          

HSP 2 Score: 33.8834 bits (76), Expect = 6.699e-12
Identity = 23/62 (37.10%), Postives = 32/62 (51.61%), Query Frame = 1

Query:  604 GKKPLDWNTR---MKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHP-KLSDFGLA 777
            G +PL + T    M      ++G+ YLH      +I+RDLK  N+LL  G    K+ DFG A
Sbjct:  118 GAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTA 179          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: Y9963_DICDI (Probable serine/threonine-protein kinase DDB_G0272254 OS=Dictyostelium discoideum GN=DDB_G0272254 PE=3 SV=1)

HSP 1 Score: 45.8246 bits (107), Expect = 8.508e-12
Identity = 22/55 (40.00%), Postives = 38/55 (69.09%), Query Frame = 1

Query:  616 LDWNTRMKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAK 780
            LD    + IA   ARG+++LH +    +I+RDLK SN+L+D+ ++ K++D G+A+
Sbjct: 1172 LDSTLILAIAFDIARGMQHLHTRN---IIHRDLKSSNLLMDKHFNIKIADLGIAR 1223          

HSP 2 Score: 45.4394 bits (106), Expect = 8.508e-12
Identity = 29/86 (33.72%), Postives = 48/86 (55.81%), Query Frame = 3

Query:  327 LGEGGFGRVYKGYLESINQVVAIKQLDRNGVQGN----REFLVEVLMLSLLHHPNLVNLIGYCADGDQRLLVYEYMPLGSVEDHLH 572
            +G+G F +V KG  +  +  VA+K+L+ N  +      +EF  EV +L  L HPNLV   GY    +   +V E++P G++ + +H
Sbjct: 1079 IGKGHFSKVLKGNWKGKD--VAVKKLNSNKDKAREEMIQEFKAEVELLGSLQHPNLVTCYGYSL--NPMCIVMEFLPSGNLFELIH 1160          

BLAST of EY756166 vs. ExPASy Swiss-Prot
Match: JAK2_CHICK (Tyrosine-protein kinase JAK2 OS=Gallus gallus GN=JAK2 PE=2 SV=1)

HSP 1 Score: 53.1434 bits (126), Expect = 8.544e-12
Identity = 31/87 (35.63%), Postives = 48/87 (55.17%), Query Frame = 3

Query:  327 LGEGGFGRV----YKGYLESINQVVAIKQLDRNGVQGNREFLVEVLMLSLLHHPNLVNLIGYCADGDQR--LLVYEYMPLGSVEDHL 569
            LG+G FG V    Y    ++  +VVA+K+L  +  +  R+F  E+ +L  L H N+V   G C    +R   L+ EY+P GS+ D+L
Sbjct:  852 LGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYL 938          

HSP 2 Score: 38.1206 bits (87), Expect = 8.544e-12
Identity = 22/64 (34.38%), Postives = 34/64 (53.12%), Query Frame = 1

Query:  595 LSPGKKPLDWNTRMKIAAGAARGLEYLHDKAKPPVIYRDLKCSNILLDRGYHPKLSDFGLAKLV 786
            L   K+ LD    +  A+   +G+EYL  K     ++RDL   NIL++     K+ DFGL K++
Sbjct:  938 LQKHKERLDHKKLLLYASQICKGMEYLGTKR---YVHRDLATRNILVENENRVKIGDFGLTKVL 998