EY728772

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: SAE2_DICDI (SUMO-activating enzyme subunit 2 OS=Dictyostelium discoideum GN=uba2 PE=3 SV=1)

HSP 1 Score: 112.079 bits (279), Expect = 4.134e-24
Identity = 66/198 (33.33%), Postives = 98/198 (49.49%), Query Frame = 1

Query:   16 ISVFGAKLQKKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEF 609
            I   G     K++  K+ +VG+G +GCE LKN+ L G        + I D D I+ SNL+RQFLFR  +IG              N ++NI A     G    + F   F++    V+NALDN++AR +V++ CL    P++ESGT G      ++    TE +        KQ  +CT+ + P    HC+ WA+  F
Sbjct:    9 IQALGQSTFDKIQTCKILVVGAGGIGCELLKNLVLTGFK-----NIDIIDLDTIDISNLNRQFLFRKQHIGMSKAKIAKESVMKYNEQVNITAHH---GDVKSSEFGSEFFKQFDLVMNALDNISARRHVNRLCLSVDVPMIESGTAGYLGQVSVIRKGKTECFECQPIAVPKQFAVCTIRTNPSAPIHCIVWAKMLF 198          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: SAE2A_XENLA (SUMO-activating enzyme subunit 2-A OS=Xenopus laevis GN=uba2-A PE=2 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 9.209e-24
Identity = 71/212 (33.49%), Postives = 109/212 (51.42%), Query Frame = 1

Query:   16 ISVFGAKLQKKLEDA----KVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAE 639
            ++V GA L K++ +A    ++ +VG+G +GCE LKN+ L G +      L + D D I+ SNL+RQFLF+  ++G+              P  NI A  + +     NV    F++  T  +NALDN  AR +V++ CL    PL+ESGT G      ++   +TE Y     P +K  P CT+ + P    HC+ WA+  F  L  +  A+
Sbjct:    1 MAVIGA-LPKEVAEAVSASRLLVVGAGGIGCELLKNLVLTGFT-----NLDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPDANITAYHDSIMNPDYNV---EFFKQFTMAMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVSVIKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDAD 203          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: SAE2_HUMAN (SUMO-activating enzyme subunit 2 OS=Homo sapiens GN=UBA2 PE=1 SV=2)

HSP 1 Score: 110.153 bits (274), Expect = 1.571e-23
Identity = 66/202 (32.67%), Postives = 101/202 (50.00%), Query Frame = 1

Query:   34 KLQKKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAE 639
            +L + +   +V +VG+G +GCE LKN+ L G S      + + D D I+ SNL+RQFLF+  ++G+              P+ NI A  + +     NV    F+     V+NALDN  AR +V++ CL    PL+ESGT G       +   +TE Y     P ++  P CT+ + P    HC+ WA+  F  L  +  A+
Sbjct:   10 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFS-----HIDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNV---EFFRQFILVMNALDNRAARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDAD 203          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: UBA2_YEAST (Ubiquitin-activating enzyme E1-like OS=Saccharomyces cerevisiae GN=UBA2 PE=1 SV=1)

HSP 1 Score: 108.997 bits (271), Expect = 3.499e-23
Identity = 68/201 (33.83%), Postives = 102/201 (50.75%), Query Frame = 1

Query:   16 ISVFGAKLQKKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFD-DTF----WENITCVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARS 603
            +++ G    KKL  ++  +VG+G +G E LK++ LM       G++ I D D I+ SNL+RQFLFR  +I Q             N         +++ P   NV D  TF    +E    + NALDN+ AR YV++   +   PL+ESGT G     Q +IP  TE +  ++    K  P+CT+ S P    HC+ WA++
Sbjct:    8 VTIIGEDSYKKLRSSRCLLVGAGGIGSELLKDIILMEF-----GEIHIVDLDTIDLSNLNRQFLFRQKDIKQPKSTTAVKAVQHFN--------NSKLVPYQGNVMDISTFPLHWFEQFDIIFNALDNLAARRYVNKISQFLSLPLIESGTAGFDGYMQPIIPGKTECFECTKKETPKTFPVCTIRSTPSQPIHCIVWAKN 195          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: SAE2B_XENLA (SUMO-activating enzyme subunit 2-B OS=Xenopus laevis GN=uba2-B PE=2 SV=2)

HSP 1 Score: 108.997 bits (271), Expect = 3.499e-23
Identity = 70/212 (33.02%), Postives = 109/212 (51.42%), Query Frame = 1

Query:   16 ISVFGAKLQKKLEDA----KVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAE 639
            ++V GA L K++ +A    ++ +VG+G +GCE LKN+ L G +      L + D D I+ SNL+RQFLF+  ++G+              P  +I A  + +     NV    F++  T  +NALDN  AR +V++ CL    PL+ESGT G      ++   +TE Y     P +K  P CT+ + P    HC+ WA+  F  L  +  A+
Sbjct:    1 MAVIGA-LPKEVAEAVSASRLLVVGAGGIGCELLKNLVLTGFT-----NLDVIDLDTIDVSNLNRQFLFQKKHVGRSKAQVAKESVLQFCPDASITAYHDSIMNPDYNV---EFFKQFTMAMNALDNNAARNHVNRMCLAAGIPLIESGTAGYLGQVSVIKKGVTECYECQPKPTQKTFPGCTIRNTPSEPIHCIVWAKYLFNQLFGEEDAD 203          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: UBA3_PONAB (NEDD8-activating enzyme E1 catalytic subunit OS=Pongo abelii GN=UBA3 PE=2 SV=2)

HSP 1 Score: 100.523 bits (249), Expect = 1.245e-20
Identity = 62/202 (30.69%), Postives = 101/202 (50.00%), Query Frame = 1

Query:   37 LQKKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQK------------PLLESGTLGAKCNTQMVIPHLTENYGASRD--PPEKQAPMCTVHSFPHNIDHCLTWAR 600
            LQ  L+  KV ++G+G LGCE LKN+AL G       ++ + D D I+ SNL+RQFLFR  +IG+              P  N+    N++       F+DTF+     ++  LD++ AR +++   +                PL++ GT G K N ++++P +T     + +  PP+   PMCT+ S P   +HC+ + R
Sbjct:   63 LQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-----QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKI-----QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVR 254          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: UBA3_HUMAN (NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens GN=UBA3 PE=1 SV=2)

HSP 1 Score: 100.523 bits (249), Expect = 1.245e-20
Identity = 62/202 (30.69%), Postives = 101/202 (50.00%), Query Frame = 1

Query:   37 LQKKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQK------------PLLESGTLGAKCNTQMVIPHLTENYGASRD--PPEKQAPMCTVHSFPHNIDHCLTWAR 600
            LQ  L+  KV ++G+G LGCE LKN+AL G       ++ + D D I+ SNL+RQFLFR  +IG+              P  N+    N++       F+DTF+     ++  LD++ AR +++   +                PL++ GT G K N ++++P +T     + +  PP+   PMCT+ S P   +HC+ + R
Sbjct:   63 LQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-----QIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKI-----QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVR 254          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: UBA3_RAT (NEDD8-activating enzyme E1 catalytic subunit OS=Rattus norvegicus GN=Uba3 PE=1 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.626e-20
Identity = 61/202 (30.20%), Postives = 101/202 (50.00%), Query Frame = 1

Query:   37 LQKKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQK------------PLLESGTLGAKCNTQMVIPHLTENYGASRD--PPEKQAPMCTVHSFPHNIDHCLTWAR 600
            LQ  L+  KV ++G+G LGCE LKN+AL G       ++ + D D I+ SNL+RQFLFR  ++G+              P  N+    N++       F+DTF+     ++  LD++ AR +++   +                PL++ GT G K N ++++P +T     + +  PP+   PMCT+ S P   +HC+ + R
Sbjct:   63 LQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-----QIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKI-----QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVR 254          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: UBA3_MOUSE (NEDD8-activating enzyme E1 catalytic subunit OS=Mus musculus GN=Uba3 PE=2 SV=1)

HSP 1 Score: 100.138 bits (248), Expect = 1.626e-20
Identity = 61/202 (30.20%), Postives = 101/202 (50.00%), Query Frame = 1

Query:   37 LQKKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQK------------PLLESGTLGAKCNTQMVIPHLTENYGASRD--PPEKQAPMCTVHSFPHNIDHCLTWAR 600
            LQ  L+  KV ++G+G LGCE LKN+AL G       ++ + D D I+ SNL+RQFLFR  ++G+              P  N+    N++       F+DTF+     ++  LD++ AR +++   +                PL++ GT G K N ++++P +T     + +  PP+   PMCT+ S P   +HC+ + R
Sbjct:   63 LQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-----QIHVIDMDTIDVSNLNRQFLFRPKDVGRPKAEVAAEFLNDRVPNCNVVPHFNKI-----QDFNDTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIASMPRLPEHCIEYVR 254          

BLAST of EY728772 vs. ExPASy Swiss-Prot
Match: SAE2_CAEEL (SUMO-activating enzyme subunit uba-2 OS=Caenorhabditis elegans GN=uba-2 PE=2 SV=3)

HSP 1 Score: 96.6709 bits (239), Expect = 1.797e-19
Identity = 58/193 (30.05%), Postives = 98/193 (50.78%), Query Frame = 1

Query:   43 KKLEDAKVFIVGSGALGCEFLKNVALMGVSCGNQGKLTITDDDVIEKSNLSRQFLFRDWNIGQXXXXXXXXXXXXINPRLNIEALQNRVGPETENVFDDTFWENITCVINALDNVNARLYVDQRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQA-PMCTVHSFPHNIDHCLTWARSEFEGL 618
            +K+  +K+ ++G+G +GCE LKN+A+ G       K+ + D D I+ SNL+RQFLFR  ++                P++ +    + +    E  ++  F++    V+NALDN  AR YV++ C    +PL++SG+ G      +++   TE Y     P ++   P CT+ + P    HC  WA+  F  L
Sbjct:    9 EKIVQSKILVIGAGGIGCELLKNLAVTGFR-----KVHVIDLDTIDISNLNRQFLFRKEHVSSSKAATATQVVKQFCPQIELTFDHDSI---FEKKYNMEFFQAYDIVLNALDNRAARNYVNRMCHAANRPLIDSGSGGYFGQVSVIMRGKTECYECVDKPVQQTTYPGCTIRNTPSEHIHCTVWAKHVFNQL 193