EY728655

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: XYL1_PICGU (NADPH-dependent D-xylose reductase OS=Pichia guilliermondii GN=XYL1 PE=1 SV=2)

HSP 1 Score: 174.866 bits (442), Expect = 5.533e-43
Identity = 103/290 (35.52%), Postives = 153/290 (52.76%), Query Frame = 1

Query:   43 MAITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGT--TDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG----AVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            M+ITLN+G++MP +G G W++D++   D I NAIK+GYR  D A DY NE EVGE +  A   GLV R++LF+ +KLWNS H   +V +A   +             +HFP+A K               DG   I   + +  TW A+E +V  G +RSIGISN+   L +D L  +K+KP V Q E HPY Q+  L+++ Q  GI +TA++  G      + +          +  V+K + EK  +T AQ++LRW               +    N +V+DFDL+++
Sbjct:    1 MSITLNSGYEMPSVGFGCWKVDKATCADTIYNAIKVGYRLFDGAEDYGNEKEVGEGINRALDEGLVARDELFVVSKLWNSFHDPKNVEKALDRTLSDLKVDYLDLFLIHFPIAFKFVPFEEKYPPGFYCGDGDKFIYEGVPIIDTWRALEKMVEKGKIRSIGISNFPGALIQDLLRGAKIKPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFVELNHPRVKDVKPLFEHDVIKSVAEKANKTPAQVLLRWATQRGLAVIPKSNNPDRLLSNLKVNDFDLSQE 290          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALRA_DICDI (Aldose reductase A OS=Dictyostelium discoideum GN=alrA PE=2 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 5.533e-43
Identity = 96/252 (38.10%), Postives = 143/252 (56.75%), Query Frame = 1

Query:   55 LNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFST-GLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLG-GAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            L++G K+P++G G W+ + + +   +  A+  GYRHIDCAA Y NE EVGEA  + F+T   VKRED+FIT+KLWN+ H   HV  A + +             VH+PVA ++T      S    + V       S+  TW  ME LV  GLV+SIG+SN+++    + L+Y+++KP  NQ E HP+  +  L KFC KH I +TA++PLG GA  + E  G ++           +KY +T+  ++ +W I
Sbjct:    7 LSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSNDIQTSGSTQEFV-------SIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGNGAFVDNEEVGAIA-----------KKYNKTIPNVLCKWAI 240          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1A1_PONAB (Alcohol dehydrogenase [NADP+] OS=Pongo abelii GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 174.866 bits (442), Expect = 5.533e-43
Identity = 99/253 (39.13%), Postives = 145/253 (57.31%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            + L+ G KMP+IGLG W+ +   ++  +  A+ +GYRHIDCAA Y NE E+GEAL E    G  V RE+LF+T+KLWN+ H    V  A + +             +H+P A +    G      +ADG +  D+T   ET W A+E LV+ GLVR++G+SN++     D L+ + V+P V Q E HPY  ++ L+  CQ  G+ VTA++PLG +            L++PV+  L EKY  + AQI+LRW +
Sbjct:    6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALQKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNADGTICYDSTHYKET-WKALEALVAKGLVRALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLAVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGGSPAQILLRWQV 254          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1A1_HUMAN (Alcohol dehydrogenase [NADP+] OS=Homo sapiens GN=AKR1A1 PE=1 SV=3)

HSP 1 Score: 174.866 bits (442), Expect = 5.533e-43
Identity = 99/253 (39.13%), Postives = 146/253 (57.71%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            + L+ G KMP+IGLG W+ +   ++  +  A+ +GYRHIDCAA Y NE E+GEAL E    G  V RE+LF+T+KLWN+ H    V  A + +             +H+P A +    G      +ADG +  D+T   ET W A+E LV+ GLV+++G+SN++     D L+ + V+P V Q E HPY  ++ L+  CQ  G+ VTA++PLG +            L++PV+  L EKY R+ AQI+LRW +
Sbjct:    6 VLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNADGTICYDSTHYKET-WKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEKYGRSPAQILLRWQV 254          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALDR_BOVIN (Aldose reductase OS=Bos taurus GN=AKR1B1 PE=1 SV=1)

HSP 1 Score: 174.481 bits (441), Expect = 7.226e-43
Identity = 108/284 (38.03%), Postives = 149/284 (52.46%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            I L  G KMPI+GLG W+     + + +  AI +GYRHIDCA  Y+NE EVG AL       +VKREDLFI +KLW + H    V  AC+ +             +H+P   K    G     LD DG + I +      TW AME+LV  GLV++IG+SN++       L     K KP VNQ E HPY  ++ L+++C   GI VTA++PLG            S L+DP +K + +KY +T AQ+++R+ I             E   EN +V DF+L K+
Sbjct:    4 IVLYTGAKMPILGLGTWKSPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLALQAKLQEQVVKREDLFIVSKLWCTYHDKDLVKGACQKTLSDLKLDYLDLYLIHWPTGFK---PGKDFFPLDEDGNV-IPSEKDFVDTWTAMEELVDEGLVKAIGVSNFNHLQVEKILNKPGLKYKPAVNQIECHPYLTQEKLIQYCNSKGIVVTAYSPLGSPDRPWAKPEDPSILEDPRIKAIADKYNKTTAQVLIRFPIQRNLIVIPKSVTPERIAENFQVFDFELDKE 283          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1A1_MOUSE (Alcohol dehydrogenase [NADP+] OS=Mus musculus GN=Akr1a1 PE=1 SV=3)

HSP 1 Score: 174.481 bits (441), Expect = 7.226e-43
Identity = 96/254 (37.80%), Postives = 148/254 (58.27%), Query Frame = 1

Query:   46 AITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            ++ L+ G KMP+IGLG W+ +   ++  I +A+  GYRHIDCA+ Y NE E+GEAL E+  +G  V RE+LF+T+KLWN+ H    V  A + +             +H+P A +    G      +ADG +  D+T   + TW A+E LV+ GLV+++G+SN++     D L+ + V+P V Q E HPY  ++ L+  C   G+ VTA++PLG +            L++PV+  L EK+ R+ AQI+LRW +
Sbjct:    5 SVLLHTGQKMPLIGLGTWKSEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNADGTVRYDST-HYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGRSPAQILLRWQV 254          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALRB_DICDI (Aldose reductase B OS=Dictyostelium discoideum GN=alrB PE=3 SV=2)

HSP 1 Score: 173.326 bits (438), Expect = 1.610e-42
Identity = 95/245 (38.78%), Postives = 142/245 (57.96%), Query Frame = 1

Query:   73 MPIIGLGVWRMDE-SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGV-GTTDSAL-DADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRW 792
            +P+IGLG +   +   + D +  A+K GYRHID AA Y NE E+G AL E F+ G +KRED+F  +KLWNS H    V + C+ +             +H+P+A ++    GTT   L D+DG   +   +S+  TW  ME LV  GLV+SIG+SN+++    D L Y+K+KP +NQ E HPY  + +L  FC ++GI +TA++PLG         G    L +  LK + +K+ +TVA ++ +W
Sbjct:   17 IPMIGLGTYNGAKVGEVGDAVKVALKSGYRHIDGAAIYMNEKEIGHALKEVFAEGEIKREDIFYVSKLWNSCHHASLVRKHCEKTLEDLGLEYLDLYLIHWPIAFENADPSGTTTQPLRDSDGE-PVLAAVSIRETWQEMEKLVEYGLVKSIGVSNFNVQNLVDLLTYAKIKPAINQVEVHPYLSQPNLKYFCDRYGIVLTAYSPLGQ--------GKCDLLSNETLKSIADKHNKTVANVIFKW 252          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALRC_DICDI (Aldose reductase C OS=Dictyostelium discoideum GN=alrC PE=3 SV=1)

HSP 1 Score: 172.94 bits (437), Expect = 2.103e-42
Identity = 95/250 (38.00%), Postives = 142/250 (56.80%), Query Frame = 1

Query:   55 LNNGFKMPIIGLGVWRMDE-SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTG-VGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRW 792
            LN+G ++P IGLG +  +    + D I NA+K GYRHID AA Y NE  +G +L E F  G +KRED+F T+KLWNS H    V++ C  +             +H+P+A +++  +G T   L       I   +S+  TW  ME LV +GLV+SIG+SN+++    D L Y+K+KPVVNQ E HPY  +  L ++C K+ I + A++PLG         G      + +LK +  KY ++VA ++ +W
Sbjct:   19 LNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLGQ--------GKCDFFSNKILKSIAGKYKKSVANVIFKW 260          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: XYL2_CANTR (NADPH-dependent D-xylose reductase II,III OS=Candida tropicalis GN=xyrB PE=1 SV=1)

HSP 1 Score: 172.555 bits (436), Expect = 2.746e-42
Identity = 103/290 (35.52%), Postives = 148/290 (51.03%), Query Frame = 1

Query:   40 IMAITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGT--TDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG----AVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTK 882
            I  I LN+G++MP++G G W+++     D I NAIK GYR  D A DY NE EVGE +  A   GLVKRE+LFIT+KLWN+ H   +V  A   +             +HFP+A K   +           DG       + L  TW A+E LV  G ++SIGISN+   L  D +  + +KP V Q E HPY Q+  L+++ QK GI +T ++  G      + +     T +  +   +K + +K+ ++ AQ++LRW               E   +N  V DFDLTK
Sbjct:    7 IPTIKLNSGYEMPLVGFGCWKVNNETAADQIYNAIKTGYRLFDGAEDYGNEKEVGEGINRAIKEGLVKREELFITSKLWNNFHDPKNVETALNKTLSDLNLDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFHYEDVPLLDTWKALEKLVEAGKIKSIGISNFTGALIYDLIRGATIKPAVLQIEHHPYLQQPKLIEYVQKAGIAITGYSSFGPQSFLELESKRALNTPTLFEHETIKSIADKHGKSPAQVLLRWATQRNIAVIPKSNNPERLAQNLSVVDFDLTK 296          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALDR_RAT (Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3)

HSP 1 Score: 172.555 bits (436), Expect = 2.746e-42
Identity = 108/285 (37.89%), Postives = 149/285 (52.28%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADG-VLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI-XXXXXXXXXXXXXETGENSRVDDFDLTKK 885
            + LNNG KMP +GLG W+     + + +  AI +GYRHIDCA  Y+NE EVG AL E     +VKR+DLFI +KLW +  D   V  AC+ +             +H+P   K    G     LDA G V+  DT      TW AME LV  GLV++IG+SN++       L     K KP VNQ E HPY  ++ L+++C   GI VTA++PLG            S L+DP +K +  KY +T AQ+++R+ I                 EN +V DF+L+ +
Sbjct:    5 LELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFK---PGPDYFPLDASGNVIPSDT--DFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNE 284