EY728655

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1A1_XENLA (Alcohol dehydrogenase [NADP+] OS=Xenopus laevis GN=akr1a1 PE=2 SV=1)

HSP 1 Score: 163.31 bits (412), Expect = 1.666e-39
Identity = 93/252 (36.90%), Postives = 140/252 (55.56%), Query Frame = 1

Query:   52 TLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGL-VKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            TL  G KMP+IGLG W+     ++D +  A+ +GYRHIDCA  Y NE EVGEA+ E+      +KRE++F+T+KLWN+ H    V  A + +             +H+P A K    G      + DG ++ D T   + TW AME LV  GL ++IG+SN++     D L+ + VKP V Q E HPY  ++ L+  C+ HG+ +T ++PLG    +         L++P +  + +KY  + AQI+LRW +
Sbjct:    9 TLYTGQKMPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGPDKGLKREEVFVTSKLWNNKHHPDDVECALRKTLQELQLDYLDLYLMHWPYAFKR---GDQVFPQNPDGSVQYDLT-DYKDTWKAMEKLVEKGLAKAIGLSNFNKRQMDDILSIATVKPAVLQVECHPYLAQNELIACCRSHGLVLTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYNISEAQILLRWQV 256          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: GRE3_YEAST (NADPH-dependent aldose reductase GRE3 OS=Saccharomyces cerevisiae GN=GRE3 PE=1 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 2.842e-39
Identity = 95/265 (35.85%), Postives = 144/265 (54.34%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGV------GTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG--------AVXNTEWFGTVSCLDDPVLKGLPEKY-XRTVAQIVLRW 792
            +TLNNG KMP++GLG W++D+    + I  AIK+GYR  D A DY NE EVGE + +A S GLV R+D+F+ +KLWN+ H   HV  A K +             +HFP+A K+         G    A D       +  + +  T+ A+E+ V  GL++SIG+SN+   L +D L   ++KPV  Q E HPY  ++ LV+FC+ H I V A++  G          +  T    T +  ++ V+K + + +   T +Q++LRW
Sbjct:    5 VTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKYVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQSFIEMDLQLAKT----TPTLFENDVIKKVSQNHPGSTTSQVLLRW 265          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1A1_XENTR (Alcohol dehydrogenase [NADP+] OS=Xenopus tropicalis GN=akr1a1 PE=2 SV=1)

HSP 1 Score: 162.54 bits (410), Expect = 2.842e-39
Identity = 90/252 (35.71%), Postives = 140/252 (55.56%), Query Frame = 1

Query:   52 TLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGL-VKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            TL  G K+P+IGLG W+     ++D +  A+ +GYRHIDCA  Y NE EVGEA+ E+  +   + RE++F+T+KLWN+ H    V  A + +             +H+P A K    G      + DG ++ D T   + TW AME LV  GL ++IG+SN++     D ++ + VKP V Q E HPY  ++ L+ +C  HG+  T ++PLG    +         L++P +  + +KY ++ AQI+LRW +
Sbjct:    9 TLYTGQKIPLIGLGTWKSAPGQVKDAVKYALGVGYRHIDCAFVYGNETEVGEAIKESVGSDKGLSREEVFVTSKLWNNKHHPDDVECALRKTLQDLQLDYLDLYLMHWPYAFKR---GDQIFPQNPDGSVQYDLT-DYKDTWKAMEKLVKQGLTKAIGLSNFNKRQIDDIISIATVKPAVLQVECHPYLAQNELIAYCHAHGLVFTGYSPLGSPDRSWRKPEDPVLLEEPGIIAMAKKYGKSEAQILLRWQV 256          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: XYL1_CANPA (NADH-dependent D-xylose reductase OS=Candida parapsilosis GN=XYL1 PE=1 SV=1)

HSP 1 Score: 159.844 bits (403), Expect = 1.842e-38
Identity = 98/288 (34.03%), Postives = 144/288 (50.00%), Query Frame = 1

Query:   46 AITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGT--TDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG----AVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTK 882
            A+ LN+G+++P++G G W++      D I  AIK GYR  D A DY NE EVGE +  A   G+VKRE+LFIT+KLWNS H   +V  A   +             +HFP+A K   +           DG       + L  TW A+E LV  GL +SIGISN+   L  D +    +KPV  Q E HPY  +  LV++ Q H I +T ++  G      +       T   L++P +K + +K+ ++ AQ++LR+               +   +N  V DF+LT+
Sbjct:    9 AVKLNSGYEIPLVGFGCWKLTNDVASDQIYRAIKSGYRLFDGAEDYANEQEVGEGIKRAIKEGIVKREELFITSKLWNSFHDKKNVEVALMKTLSDLNLDYVDLFYIHFPIAQKPVPIEKKYPPGFYCGDGDKWSIEEVPLLDTWRALEKLVDQGLAKSIGISNFSAQLIYDLIRGCTIKPVALQIEHHPYLTQPKLVEYVQLHDIQITGYSSFGPQSFLEMDLKRALDTPVLLEEPTVKSIADKHGKSPAQVLLRYQTQRGIAVIPRSNSPDRMAQNLSVIDFELTQ 296          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1D1_MOUSE (3-oxo-5-beta-steroid 4-dehydrogenase OS=Mus musculus GN=Akr1d1 PE=2 SV=1)

HSP 1 Score: 159.458 bits (402), Expect = 2.406e-38
Identity = 110/292 (37.67%), Postives = 152/292 (52.05%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVW---RMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            I+L++G  +P+IGLG +   R         +  AI  GYRHID A  Y NE EVGEA+ E  + G VKRE++F   KLWN++H    VL A + +             +  P+A K    G      D +G +  D T +L  TW A+E     GLV+S+G+SN+     ++ L +  L Y   KPV NQ E HPYF +  L+KFCQ+H I + AH+PL G   N  W    S   L+D +L  L +KY +T AQIVLR+ I             E   EN ++ DF LT++
Sbjct:   10 ISLSDGNNIPLIGLGTYSDPRPVPGKTYVAVKTAIDEGYRHIDGAYVYHNEHEVGEAIREKIAEGKVKREEIFYCGKLWNTEHVPSMVLPALERTLKALKLDYIDLYIIELPMAFK---PGKEIYPRDENGRIIYDKT-NLCATWEALEACKDAGLVKSLGVSNFNRRQLELILNKPGLKY---KPVTNQVECHPYFTQTKLLKFCQQHDIVIVAHSPL-GTCRNPSWVNVSSPPLLNDELLTSLGKKYNKTQAQIVLRFNIQRGIVVIPKSFTPERIKENFQIFDFSLTEE 293          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALD1_MOUSE (Aldose reductase-related protein 1 OS=Mus musculus GN=Akr1b7 PE=2 SV=4)

HSP 1 Score: 158.688 bits (400), Expect = 4.103e-38
Identity = 97/284 (34.15%), Postives = 149/284 (52.46%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI-XXXXXXXXXXXXXETGENSRVDDFDLTKK 885
            + L+   KMP++GLG W+     +++ +  AI  GYRHIDCA  Y NE EVGEA+ E      VKREDLFI +KLW +  +   V +A +++             VH+P   +    G      D  G + +  +  L+  W AME+LV  GLV+++GISN++ F     L     K KPV NQ E+HPY  ++ L+++CQ  GI VTA++PLG              ++ P +K +  K+ +TVAQ+++R+ +                 EN +V DF L+++
Sbjct:    5 VELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQ---AGNALLPKDNKGKVLLSKSTFLD-AWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEE 284          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: XYL1_CANTE (NAD(P)H-dependent D-xylose reductase OS=Candida tenuis GN=XYL1 PE=1 SV=1)

HSP 1 Score: 157.918 bits (398), Expect = 6.999e-38
Identity = 95/288 (32.99%), Postives = 143/288 (49.65%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGT--TDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG----AVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            I L++G  MP IG G W++  +   + +  AIK GYR  D A DY NE EVG+ +  A   GLVKRE++F+T+KLWN+ H   +V  A   +             +HFP+A K   +           DG   +   + +  TW A+E LV+ G ++SIG+SN+   L  D L  + +KP V Q E HPY Q+  L++F QK G+ +TA++  G      +       T +      +K +  KY +T A+++LRW               E   +N   + FDLTK+
Sbjct:    8 IKLSSGHLMPSIGFGCWKLANATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGNNFVYEDVPILETWKALEKLVAAGKIKSIGVSNFPGALLLDLLRGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRALNTPTLFAHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTKE 295          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALD2_MOUSE (Aldose reductase-related protein 2 OS=Mus musculus GN=Akr1b8 PE=1 SV=2)

HSP 1 Score: 155.221 bits (391), Expect = 4.537e-37
Identity = 92/254 (36.22%), Postives = 137/254 (53.94%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            + L+   KMPI+GLG W+   + +++ +  AI  GYRHIDCA  Y NE EVGEA+ E      V+REDLFI +KLW +  +   + EA + +             +H+P   +    G      D  G +    T  LE  W  ME+LV  GLV+++G+SN++ F     L     K KPV NQ E HPY  ++ L+++C   GI VTA++PLG     +      S L+DP +K +  K+ +T AQ+++R+ I
Sbjct:    5 VELSTKAKMPIVGLGTWKSPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQEKIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQ---PGKELFPKDDQGRILTSKTTFLE-AWEGMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSLLEDPKIKEIAAKHEKTSAQVLIRFHI 254          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1BA_HUMAN (Aldo-keto reductase family 1 member B10 OS=Homo sapiens GN=AKR1B10 PE=1 SV=1)

HSP 1 Score: 154.451 bits (389), Expect = 7.739e-37
Identity = 92/254 (36.22%), Postives = 133/254 (52.36%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            + L+   KMPI+GLG W+     +++ +  AI  GYRHIDCA  Y+NE EVGEA+ E      VKREDLFI +KLW +  +   V +A + +             +H+P   K       D     D    I    +    W AME+LV  GLV+++G+SN+  F     L     K KPV NQ E HPY  ++ L+++C   GI VTA++PLG            S L+DP +K +  K+ +T AQ+++R+ I
Sbjct:    5 VELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK----SGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAKHKKTAAQVLIRFHI 254          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: DTDH_MUCMU (4-dihydromethyl-trisporate dehydrogenase OS=Mucor mucedo GN=tdh PE=1 SV=1)

HSP 1 Score: 153.295 bits (386), Expect = 1.724e-36
Identity = 94/260 (36.15%), Postives = 138/260 (53.08%), Query Frame = 1

Query:   49 ITLNN-GFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDS----ALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLG--GAVXNTEWFGT-VSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            +TLN  G KMPI G G W++D  +  + +  AIK GYR  D A DY NE EVG  + +A + GLVKREDLFI TKLWN+ H   HV                    +HFPV  ++    T         DA   L+ + +  +   W  +E +V  GL R+IG++N++     D L Y+++KP V Q E HPY  ++ LVK+ ++ GI +TA++  G    V  TE   T  S L+   +K + +K+  +  Q++LRW +
Sbjct:    6 LTLNRTGDKMPIRGFGCWKIDTKDCEETVYQAIKTGYRLFDGACDYGNEVEVGRGINKAINEGLVKREDLFIVTKLWNTFHSKKHVRALFDRQLKDTGLEYFDLYLIHFPVPLQYVDPATVYPPGWYVGDAKS-LQFEQS-PIHECWAELEKIVDAGLARNIGVANFNCQAILDLLTYARIKPAVLQIELHPYLPQERLVKWVKEQGIQITAYSSFGPTSYVDLTESGKTYTSLLEHASVKSVADKHNVSTGQVLLRWAL 263