EY728655

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: XYL1_PICST (NAD(P)H-dependent D-xylose reductase OS=Pichia stipitis GN=XYL1 PE=3 SV=1)

HSP 1 Score: 152.91 bits (385), Expect = 2.252e-36
Identity = 92/267 (34.46%), Postives = 133/267 (49.81%), Query Frame = 1

Query:   46 AITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATK------------HTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGG----AVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRW 792
            +I LN+G+ MP +G G W++D     + I  AIK GYR  D A DY NE  VG  + +A   G+VKREDLF+T+KLWN+ H   +V +A   +             +HFPV  K            + G G      D          + +  TW A+E LV  G +RSIG+SN+   L  D L  + +KP V Q E HPY Q+  L++F Q  GI VTA++  G      +       T    ++  +K +  K+ ++ AQ++LRW
Sbjct:    3 SIKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDYED----------VPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAIAAKHGKSPAQVLLRW 259          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALD2_CRIGR (Aldose reductase-related protein 2 OS=Cricetulus griseus GN=AKR1B8 PE=1 SV=3)

HSP 1 Score: 152.525 bits (384), Expect = 2.941e-36
Identity = 92/256 (35.94%), Postives = 138/256 (53.91%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWF--GTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            + L+   KMPI+GLG W+     +++ +  AI  GYRHIDCA  Y NE EVGEA+ E      V+REDLFI +KLW +  +   + EA + +             +H+P   +    G      D  G + + + I+    W  ME+LV  GLV+++G+SN++ F     L     K KPV NQ E HPY  ++ L+++C   GI VTA++PLG    N  W      S L+DP +K +  K+ +T AQ+++R+ I
Sbjct:    5 VELSTKAKMPIVGLGTWQSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQEKIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQ---PGKELFPKDDQGNV-LTSKITFLDAWEVMEELVDEGLVKALGVSNFNHFQIERILNKPGLKHKPVTNQVECHPYLTQEKLIEYCHSKGITVTAYSPLGS--PNRPWAKPEDPSLLEDPKIKEIAAKHKKTSAQVLIRFHI 254          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: YTBE_BACSU (Uncharacterized oxidoreductase ytbE OS=Bacillus subtilis GN=ytbE PE=1 SV=1)

HSP 1 Score: 150.599 bits (379), Expect = 1.117e-35
Identity = 94/281 (33.45%), Postives = 141/281 (50.18%), Query Frame = 1

Query:   52 TLNNGFKMPIIGLGVWRMDE-SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI-XXXXXXXXXXXXXETGENSRVDDFDLTK 882
            TL+NG +MP  GLGV++++E S + + +  AI  GYR ID AA Y NEA VGE + E      + REDLFIT+K+WN+D G+   L A + S             +H+PV  K+                        +  W A+E L   G +++IG+SN+ I    D +  +++KP++NQ E HP   +  L+++CQ  GI + A +PL               LD PVL  + + Y ++VAQI+LRW +                 EN+ V DF+LT+
Sbjct:   10 TLHNGVEMPWFGLGVFQVEEGSELVNAVKTAIVHGYRSIDTAAIYGNEAGVGEGIREGIEEAGISREDLFITSKVWNADLGYEETLAAFETSLSKLGLDYLDLYLIHWPVEGKY------------------------KEAWRALETLYKEGRIKAIGVSNFQIHHLEDLMTAAEIKPMINQVEFHPRLTQKELIRYCQNQGIQMEAWSPLMQG----------QLLDHPVLADIAQTYNKSVAQIILRWDLQHGIITIPKSTKEHRIKENASVFDFELTQ 256          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: ALDR_ENCCU (Aldose reductase OS=Encephalitozoon cuniculi GN=ECU01_0970 PE=1 SV=1)

HSP 1 Score: 150.599 bits (379), Expect = 1.117e-35
Identity = 89/247 (36.03%), Postives = 128/247 (51.82%), Query Frame = 1

Query:   55 LNNGFKMPIIGLGVWRM-DESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRW 792
            LNNG ++P +GLG W M DE+ +   I NA+ +GYRHID A  Y NE  +G  L + F  G+V+R+DLFIT+KLWN+ HG   +  + S             +H+PV       GT +S      V + D        W  ME LV +GL +SIGISN+    T   L   ++ P   Q E HPY  +  LV+F +  GI V +++ LG A  +     +    DD  +K + +KY    +QI+L +
Sbjct:    8 LNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTVESCGKKYNVGKFDAV----GVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAPGS-----SAKVRDDKTIKAIAKKYGCAPSQIILSY 245          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AKCL2_MACFA (1,5-anhydro-D-fructose reductase OS=Macaca fascicularis GN=AKR1E2 PE=2 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 1.906e-35
Identity = 101/297 (34.01%), Postives = 146/297 (49.16%), Query Frame = 1

Query:   73 MPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATK------------------HTGVGTTDSALD-ADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI-XXXXXXXXXXXXXETGENSRVDDFDLTK 882
            +P +GL  W+     + + +  AI  GYRH +CA  Y NE EVG  +      G V+REDLFI +KLW + H    V  AC+ S             +H+P+  K                  H GV   D  LD +D V+  DT      TW AMEDLV  GLV++IG+SN+     +  L +  L +   KPV NQ E HPY  + +L+ FCQ  G+ VTA+ PLGG+         V  +DDPV++ + +++ ++ AQI++R+                   EN +V DF+LT+
Sbjct:    4 IPAVGLSCWKASPGKVTEAVKVAIDAGYRHFNCAYFYHNEKEVGAGIRYKIKEGAVRREDLFIASKLWCTCHKKSLVKTACRRSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPGV--HDLPLDESDMVIPGDT--DFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRF---KPVTNQIECHPYLTQKNLISFCQSRGVSVTAYRPLGGSCEG------VDLIDDPVIQRIAKEHSKSPAQILIRFQTQRNVIVIPGSITPSHIKENIQVFDFELTQ 287          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1A1_CRIGR (Alcohol dehydrogenase [NADP+] (Fragment) OS=Cricetulus griseus GN=AKR1A1 PE=2 SV=1)

HSP 1 Score: 149.828 bits (377), Expect = 1.906e-35
Identity = 87/232 (37.50%), Postives = 129/232 (55.60%), Query Frame = 1

Query:   79 IIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTG-LVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXR 765
            +IGLG W+ +   ++  I  A+ +GYRHIDCAA Y NE E+GEAL E    G  V RE+LF+T+KLWN+ H    V  A + +             +H+P A +    G      + DG +  D+T   ET W A+E LV+ GLV+++G+SN++     D L+ + V+P V Q E HPY  ++ L+  CQ  G+ VTA++PLG +            L++PV+  L EK+ R
Sbjct:    1 LIGLGTWKSNPGQVKAAIKYALSVGYRHIDCAAVYGNEIEIGEALKENVGPGKAVPREELFVTSKLWNTKHHPEDVEAALRKTLADLQLEYLDLYLMHWPYAFER---GDNPFPKNDDGTIRYDSTHYKET-WKALEALVAKGLVKALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHGR 228          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AKCL2_HUMAN (1,5-anhydro-D-fructose reductase OS=Homo sapiens GN=AKR1E2 PE=1 SV=2)

HSP 1 Score: 149.058 bits (375), Expect = 3.251e-35
Identity = 99/296 (33.45%), Postives = 144/296 (48.65%), Query Frame = 1

Query:   73 MPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVL--EACKDSXXXXXXXXXXXXXVHFPVATK------------------HTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI-XXXXXXXXXXXXXETGENSRVDDFDLTK 882
            +P +GL  W+     + + +  AI  GYRH DCA  Y NE EVG  +      G V+REDLFI TKLW + H   L   AC+ S             +H+P+  K                  H  V   D  LD   ++    T  L+ TW AMEDLV  GLV++IG+SN+     +  L +  L +   KP+ NQ E HPY  + +L+ FCQ   + VTA+ PLGG+         V  +D+PV+K + +++ ++ AQI++R+ I                 EN +V DF+LT+
Sbjct:    4 IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRV--QDLPLDESNMVIPSDTDFLD-TWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRF---KPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEG------VDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQ 287          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1D1_HUMAN (3-oxo-5-beta-steroid 4-dehydrogenase OS=Homo sapiens GN=AKR1D1 PE=1 SV=1)

HSP 1 Score: 147.132 bits (370), Expect = 1.235e-34
Identity = 105/293 (35.84%), Postives = 151/293 (51.54%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKI----GYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            I L++G  +PIIGLG +   +S  +     ++K+    GYRHID A  Y+NE EVGEA+ E  + G V+RED+F   KLW ++H    V    + +             +  P+A K    G      D +G      + +L  TW AME     GLV+S+G+SN+     ++ L +  L   K KPV NQ E HPYF +  L+KFCQ+H I +TA++PLG +  N  W    S   L D +L  L ++Y +T AQIVLR+ I             E   EN ++ DF LT++
Sbjct:   10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKP---GDEIYPRDENGKWLYHKS-NLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGL---KHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTS-RNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEE 294          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1D1_RABIT (3-oxo-5-beta-steroid 4-dehydrogenase OS=Oryctolagus cuniculus GN=AKR1D1 PE=2 SV=1)

HSP 1 Score: 145.976 bits (367), Expect = 2.752e-34
Identity = 103/293 (35.15%), Postives = 147/293 (50.17%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKI----GYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVL--EACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGT--VSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            I L +G  +PIIGLG +   ++  +     ++KI    GYRHID A  Y+NE EVGE   E  + G V+RED+F   KLW ++H  V+     + +             +  P+A K    G      D +G      T +L  TW A+E     GLV+S+G+SN+     ++ L +  L   K KPV NQ E HPYF +  L+KFCQ+H I + A++PL G   N  W  T     L D +L  L +KY +T AQIVLR+ +             E   EN ++ DF LT++
Sbjct:   10 IPLGDGNSIPIIGLGTYSEPKTTPKGSCATSVKIAIDTGYRHIDGAYIYQNEHEVGETFREKIAEGKVRREDIFYCGKLWATNHDPVMVRPTLERTLKVLKLDYIDLYIIEIPMAFK---PGDVVYPRDENGKWLYHKT-NLCATWEALEACKDAGLVKSLGVSNFNRQQLELLLNKPGL---KHKPVCNQVECHPYFTQPKLLKFCQQHDIIIVAYSPL-GTCRNPMWVNTSLPPLLKDTLLNSLGKKYKKTAAQIVLRFNVQRGVVVIPKSFNPERIKENFQIFDFSLTEE 294          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: P100_LEIMA (Probable reductase OS=Leishmania major GN=P100/11E PE=2 SV=2)

HSP 1 Score: 144.436 bits (363), Expect = 8.008e-34
Identity = 98/280 (35.00%), Postives = 133/280 (47.50%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIIN-AIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDL 876
            +TL+NG KMP  GLGVW+     + +  +N A+  GYRHID AA Y+NE  VG  L  +     V RED+FITTKLWN++ G+   L A ++S             +H+P              L  +G   +D+       W A E L     VR+IG+SN+ I    D LA   V P+VNQ E HP   +  L  FC    I V A +PLG              L +P+L  +  KY +T AQ++LRW I             E   EN+ + DF+L
Sbjct:    9 VTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGLRASG----VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGK---------DILSKEGKKYLDS-------WRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQG----------KLLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFEL 258