EY728655

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AKC1H_RAT (Aldo-keto reductase family 1 member C18 OS=Rattus norvegicus GN=Akr1c18 PE=1 SV=1)

HSP 1 Score: 138.272 bits (347), Expect = 5.739e-32
Identity = 99/294 (33.67%), Postives = 146/294 (49.66%), Query Frame = 1

Query:   40 IMAITLNNGFKMPIIGLGVWRMDESNIRDLIIN----AIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWF------GTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDL 876
            I  + LN+G  +P++G G +  +E N+R   +     AI +G+RHIDC+  Y+NE E+G+A+      G VKRED+F T+KLW++ H    V  + ++S             +HFPV+ K    G      D  G L +D T+ L  TW AME     GL +SIG+SN++       L     K +PV NQ E H Y  +  L+ +C+ + I + A+  LG     T+ +       T   LDDP+L  + +KY RT A I LR+ +             E   EN +V DF L
Sbjct:    5 IQKMELNDGHSIPVLGFGTYATEE-NLRKKSMESTKIAIDVGFRHIDCSHLYQNEEEIGQAIVSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSLK---PGDELLPQDEHGNLILD-TVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALG-----TQRYKYCINEDTPVLLDDPILCTMAKKYKRTPALIALRYQLERGIVTLVKSFNEERIRENLQVFDFQL 288          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: GCY_YEAST (Protein GCY OS=Saccharomyces cerevisiae GN=GCY1 PE=1 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 7.495e-32
Identity = 81/257 (31.52%), Postives = 131/257 (50.97%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXVHFPVA-----TKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAY--SKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI 798
            ++LN G ++P IGLG W+  E++    ++ A+K GYRHID AA YRNE +VG+A+ ++     V RE++F+TTKLW + H     A   S             +H+P        K+  + +  +  D    ++I T  +   TW  M++L   G  +++G+SN+ I   +D LA   +K+ P  NQ E HP   +D L+ FC+  GI V A++PLG              L +PV+  + +K       +V+ W +
Sbjct:   12 LSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQAIKDSG----VPREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYIKNEDILSVPTKKDGSRAVDI-TNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGST--------DAPLLKEPVILEIAKKNNVQPGHVVISWHV 255          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1C4_HUMAN (Aldo-keto reductase family 1 member C4 OS=Homo sapiens GN=AKR1C4 PE=1 SV=2)

HSP 1 Score: 137.887 bits (346), Expect = 7.495e-32
Identity = 100/292 (34.25%), Postives = 143/292 (48.97%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            + LN+G  MP++G G +   E   +   ++   AI+ G+RHID A  Y NE +VG A+    + G VKRED+F T+KLW +      V  A + S             +HFP+A K    G T    D +G +  D T+ L  TW  ME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPY  +  L+ FC+   I + AH+ L G   +  W    S   L+DPVL  L +K+ RT A I LR+ +             +   EN +V +F LT +
Sbjct:    8 VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALK---PGETPLPKDENGKVIFD-TVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKY---KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL-GTQRHKLWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSE 291          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1C1_PONAB (Aldo-keto reductase family 1 member C1 homolog OS=Pongo abelii GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 137.887 bits (346), Expect = 7.495e-32
Identity = 101/292 (34.59%), Postives = 144/292 (49.32%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            + LN+   MP++G G +   E   S   +    AI+ G+RHID A  Y NE +VG A+    + G VKRED+F T+KLW + H    V  A + S             VHFPV+ K    G      D +G +  D T+ L  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPYF +  L+ FC+   I + A++ L G+    +W    S   L+DPVL  L +K+ +T A I LR+ +             +   +N +V DF LT +
Sbjct:    8 VKLNDSHFMPVLGFGTYAPPEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLVHFPVSVK---PGEEVIPKDENGKILFD-TVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL-GSHREEKWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRQNMQVFDFQLTSE 291          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: PGFS2_BOVIN (Prostaglandin F synthase 2 OS=Bos taurus PE=2 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 1.279e-31
Identity = 95/290 (32.76%), Postives = 148/290 (51.03%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLW-NSDHGHVLE-ACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLT 879
            +  N+G  +P++G G +  +E   S   +    AI++G+RH+D A  Y+NE +VG+A+    + G VKRED+F T+KLW NS    ++  A + S             +H PV+ K    G      D  G L  D ++ L  TW A+E     GL +SIG+SN+     +  L +  L Y   KPV NQ E HPY  +  L++FC+ H I + A+  LG  +  +EW  + +   L+DPVL  + +K+ +T A + LR+ +             +   EN +V DF+LT
Sbjct:    8 VKFNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQVGQAIRSKIADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPVSLK---PGNKFVPKDESGKLIFD-SVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKPGLKY---KPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLL-SEWVNSNNPVLLEDPVLCAIAKKHKQTPALVALRYQVQRGVVVLAKSFNKKRIKENMQVFDFELT 289          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: PE2R_RABIT (Prostaglandin-E(2) 9-reductase OS=Oryctolagus cuniculus GN=AKR1C5 PE=1 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 1.279e-31
Identity = 91/260 (35.00%), Postives = 134/260 (51.54%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRW 792
            + L++G  +P++G G +  +E   S   +    AI  G+RHID A  Y+NE EVG A+    + G VKRED+F T+KLW + H    V  + +DS             +HFP A K    G      D  G    D T+ +  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPY  +  L++FC+  GI + A++ L G+    EW    +   L+DP++  L +K+ +T A I LR+
Sbjct:    8 VALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSKIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALK---PGVEIIPTDEHGKAIFD-TVDICATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSAL-GSHREPEWVDQSAPVLLEDPLIGALAKKHQQTPALIALRY 259          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1C1_HUMAN (Aldo-keto reductase family 1 member C1 OS=Homo sapiens GN=AKR1C1 PE=1 SV=1)

HSP 1 Score: 137.117 bits (344), Expect = 1.279e-31
Identity = 94/260 (36.15%), Postives = 134/260 (51.54%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVW---RMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRW 792
            + LN+G  MP++G G +    + +S   +    AI+ G+RHID A  Y NE +VG A+    + G VKRED+F T+KLW + H    V  A + S             +HFPV+ K    G      D +G +  D T+ L  TW A+E     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPYF +  L+ FC+   I + A++ L G+     W    S   L+DPVL  L +K+ RT A I LR+
Sbjct:    8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK---PGEEVIPKDENGKILFD-TVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSAL-GSHREEPWVDPNSPVLLEDPVLCALAKKHKRTPALIALRY 259          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1CO_HORSE (Aldo-keto reductase family 1 member C23-like protein OS=Equus caballus GN=PGFS PE=1 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 2.848e-31
Identity = 101/290 (34.83%), Postives = 139/290 (47.93%), Query Frame = 1

Query:   55 LNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNS--DHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            LN+G  +P++G G +  +E   S   ++   AI  G+RHID A  Y NE EVG+A+      G VKRED+F T+KLW +      V  A + S             +HFP+A K    G      D  G L  D T+ L  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPY  +  L+ FC+   I + A+  L G      W    S   L+DPVL  + +KY RT A I LR+ +             +   EN +V +F LT +
Sbjct:   10 LNDGHVIPVLGFGTYAPEEVPKSRTVEVTKLAIDAGFRHIDSAYSYNNEKEVGQAIRSKIEDGTVKREDIFYTSKLWLTFLRPELVRPALEKSLTNLQLDYVDLYIIHFPIALK---PGEELFPEDEHGKLIFD-TVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAYGAL-GTQRLKRWLAPNSPVLLEDPVLCAMAKKYKRTPALIALRYLLQRGVVVLAKSYNEKRIKENMQVFEFQLTSE 291          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFA (Aldo-keto reductase family 1 member C4 OS=Macaca fascicularis GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 2.848e-31
Identity = 98/292 (33.56%), Postives = 144/292 (49.32%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWF--GTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            + LN+G  MP++G G +   E   + + ++   AI+ G+RHID A  Y NE +VG A+    + G VKRED+F T+KLW +      V  A + S             +HFP+A K    G T    D +G +  D T+ L   W AME     GL +SIG+SN+     ++ L    L Y   KPV NQ E HPY  +  L+ FC+   I + AH+ L G   +  W    + + L+DPVL  L +K+ R+ A I LR+ +             +   EN +V +F LT +
Sbjct:    8 VALNDGHFMPVLGFGTYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALK---PGETPLPKDENGKVMFD-TVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKY---KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL-GTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSE 291          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1C1_MACFU (Aldo-keto reductase family 1 member C1 homolog OS=Macaca fuscata fuscata GN=AKR1C1 PE=2 SV=1)

HSP 1 Score: 135.961 bits (341), Expect = 2.848e-31
Identity = 100/292 (34.25%), Postives = 143/292 (48.97%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVW---RMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            + LN+G  MP++G G +    + ++   +    AI+ G+RHID A  Y NE  VG A+    + G VKRED+F T+KLW + H    V  A + S             +HFPV+ K    G      D +G L  D T+ L  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPY  +  L+ FC+   I + A++ L G+     W    S   L+DPVL  L +K+ RT A I LR+ +             +   EN +V +F LT +
Sbjct:    8 VKLNDGHFMPVLGFGTYAPAEVPKNKAIEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLK---PGEELIPKDENGKLLFD-TVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSAL-GSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSE 291