EY728655

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1C4_MACFU (Aldo-keto reductase family 1 member C4 OS=Macaca fuscata fuscata GN=AKR1C4 PE=1 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 4.858e-31
Identity = 98/292 (33.56%), Postives = 144/292 (49.32%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWF--GTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            + LN+G  MP++G G +   E   + + ++   AI+ G+RHID A  Y NE +VG A+    + G VKRED+F T+KLW +      V  A + S             +HFP+A K    G T    D +G +  D T+ L   W AME     GL +SIG+SN+     ++ L    L Y   KPV NQ E HPY  +  L+ FC+   I + AH+ L G   +  W    + + L+DPVL  L +K+ R+ A I LR+ +             +   EN +V +F LT +
Sbjct:    8 VALNDGHFMPVLGFGSYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYLIHFPMALK---PGETPLPKDENGKVMFD-TVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNNPGLKY---KPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSAL-GTQRHKLWVDQNSPALLEDPVLCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSE 291          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1C1_MACFA (Aldo-keto reductase family 1 member C1 homolog OS=Macaca fascicularis GN=AKR1C1 PE=1 SV=1)

HSP 1 Score: 135.191 bits (339), Expect = 4.858e-31
Identity = 100/292 (34.25%), Postives = 142/292 (48.63%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVW---RMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH--GHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            + LN+G  MP++G G +    + ++   +    AI+ G+RHID A  Y NE  VG A+    + G VKRED+F T+KLW + H    V  A + S             +HFPV+ K    G      D +G L  D T+ L  TW AME     GL +SIG+SN+     ++ L +  L Y   KPV NQ E HPY  +  L+ FC+   I + A + L G+     W    S   L+DPVL  L +K+ RT A I LR+ +             +   EN +V +F LT +
Sbjct:    8 VKLNDGHFMPVLGFGTYAPAEVPKNKALEATKLAIEAGFRHIDSAHLYNNEEYVGLAIRSKIADGTVKREDIFYTSKLWCNSHRPEFVRPALERSLKNLQLDYVDLYLIHFPVSLK---PGEELIPKDENGKLLFD-TVDLCATWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKY---KPVCNQVECHPYLNQRKLLDFCKSKDIVLVAFSAL-GSHREKPWVDQNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENMKVFEFQLTSE 291          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: DHB5_MOUSE (Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 8.287e-31
Identity = 97/289 (33.56%), Postives = 142/289 (49.13%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDH-GHVLEAC-KDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYS--KVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            + L++G  +PI+G G +   E   S   +    AI  G+RHID A+ Y+NE EVG A+    + G VKRED+F T+K+W + H   ++  C + S             +HFP+A K    G      D +G L  D  + +  TW AME     GL +SIG+SN++       L     K KPV NQ E HPY  +  L+ FC+   I + A++ L G+    +W    S   LD+PVL  + +KY RT A I LR+ +             +   EN +V +F LT +
Sbjct:    8 VRLSDGHFIPILGFGTYAPQEVPKSKATEATKIAIDAGFRHIDSASMYQNEKEVGLAIRSKIADGTVKREDIFYTSKVWCTFHRPELVRVCLEQSLKQLQLDYVDLYLIHFPMAMK---PGENYLPKDENGKLIYD-AVDICDTWEAMEKCKDAGLAKSIGVSNFNRRQLEKILKKPGLKYKPVCNQVECHPYLNQGKLLDFCRSKDIVLVAYSAL-GSHREKQWVDQSSPVLLDNPVLGSMAKKYNRTPALIALRYQLQRGVVVLAKSFSEKRIKENMQVFEFQLTSE 291          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1CN_HORSE (Aldo-keto reductase family 1 member C23 OS=Equus caballus GN=AKR1C23 PE=1 SV=1)

HSP 1 Score: 134.42 bits (337), Expect = 8.287e-31
Identity = 95/260 (36.54%), Postives = 128/260 (49.23%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDE---SNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSD--HGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRW 792
            + LN+G  +  +G G +  +E   S   +   +AI  G+RHIDCA  Y NE EVG A+      G VKRED+F T+KLW +      V  A + S             +HFPVA K    G      D  G +  D T+ L  TW AME     GL +SIG+SN+     ++ L +  L   K KPV NQ E HPY  +  L+ FC+   I + A++ LG       W    S   L+DPVL  + +KY RT A I LR+
Sbjct:    8 VELNDGHFIHALGFGTYAPNEVPKSKAVEATKSAIDAGFRHIDCAHLYDNEKEVGLAIRSKIQDGTVKREDIFCTSKLWATSLRLQLVRPALEKSLKNLQLDYVDLYIIHFPVAVK---PGEEHLPQDEQGRMIFD-TVDLCATWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGL---KHKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAYSALGS--QREHWIDQSSPVLLEDPVLCAMAKKYKRTPALIALRY 258          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: DKGA_ECOLI (2,5-diketo-D-gluconic acid reductase A OS=Escherichia coli (strain K12) GN=dkgA PE=1 SV=3)

HSP 1 Score: 133.65 bits (335), Expect = 1.414e-30
Identity = 87/248 (35.08%), Postives = 118/248 (47.58%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRW 792
            I L +G  MP +GLGVW+     +   I  A+++GYR ID AA Y+NE  VG+AL  A     V RE+LFITTKLWN DH    EA  DS             +H+PV                     ID  +     W  M +L   GL++SIG+ N+ I   +  +  + V PV+NQ E HP  Q+  L  +   H I   + +PL          G     D  V++ L +KY +T AQIV+RW
Sbjct:    7 IKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNA----SVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYIDLYLMHWPVPA-------------------IDHYVE---AWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQRQLHAWNATHKIQTESWSPLAQ--------GGKGVFDQKVIRDLADKYGKTPAQIVIRW 220          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: Y2408_MYCS2 (Uncharacterized oxidoreductase MSMEG_2408 OS=Mycobacterium smegmatis GN=MSMEG_2408 PE=3 SV=1)

HSP 1 Score: 133.265 bits (334), Expect = 1.846e-30
Identity = 92/280 (32.86%), Postives = 128/280 (45.71%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLT 879
            ITLN+G  +P +GLGVW+    +    +  A++ GYRHID AA YRNE E G A+A +     V RED+F+ TKLWNSD G+   L A   S             +H+PV   +  V                       T+ A   L   G +RSIG+SN++       +  + + P VNQ E HP   +  L     K GI   A +PLG            S L DPV+ G+ E++ +T AQ+++RW I             E    N  V DF+L+
Sbjct:    5 ITLNDGNSIPQVGLGVWQTPAEDTERAVAAALQAGYRHIDTAAAYRNETETGRAIANSG----VPREDIFLVTKLWNSDQGYDATLAAFDASVQRLGVDYLDLYLIHWPVPENNKFV----------------------DTFKAFAHLRDQGRIRSIGVSNFEPEHLTTLIEETGIVPAVNQIELHPLLPQQELRDVHAKLGIATEAWSPLGQG----------SLLADPVITGIAEQHGKTPAQVLIRWHIQLGNIVIPKSVNPERIASNFDVFDFELS 248          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: DKGA_ECO57 (2,5-diketo-D-gluconic acid reductase A OS=Escherichia coli O157:H7 GN=dkgA PE=3 SV=1)

HSP 1 Score: 132.88 bits (333), Expect = 2.411e-30
Identity = 86/248 (34.68%), Postives = 117/248 (47.18%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRW 792
            I L +G  MP +GLGVW+     +   I  A+++GYR  D AA Y+NE  VG+AL  A     V RE+LFITTKLWN DH    EA  DS             +H+PV                     ID  +     W  M +L   GL++SIG+ N+ I   +  +  + V PV+NQ E HP  Q+  L  +   H I   + +PL          G     D  V++ L +KY +T AQIV+RW
Sbjct:    7 IKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSFDTAAAYKNEEGVGKALKNA----SVNREELFITTKLWNDDHNRPREALLDSLKKLQLDYIDLYLMHWPVPA-------------------IDHYVE---AWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQIELHPLMQQRQLHAWNATHKIQTESWSPLAQ--------GGKGVFDQKVIRDLADKYGKTPAQIVIRW 220          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: NADO1_ORYSJ (Probable NAD(P)H-dependent oxidoreductase 1 OS=Oryza sativa subsp. japonica GN=Os10g0113000 PE=1 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 7.015e-30
Identity = 81/246 (32.93%), Postives = 131/246 (53.25%), Query Frame = 1

Query:   73 MPIIGLGVWRMDESNIRDL---IINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLV-KREDLFITTKLWNSD--HGHVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRW 792
            MP +G+G      ++  D    ++ AI++GYRH D A  Y  E  VGEA+AEA   GL+  R D+F+T+K+W SD   G V+ A +++             VH+PV+      G  D     + +L    +  +E  W  ME+   +GL R+IG+SN+        L+ + V+P VNQ E +P +Q+ +L + C++ G+ +  ++PLG     T W G+ + +D  VL+ +     +T+AQI LRW
Sbjct:   16 MPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTP---GNYDFPFPKEVILP---SFDMEGVWRGMEECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLG--AKGTPW-GSAAVMDSGVLQEIAGAKGKTLAQICLRW 252          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: AK1D1_RAT (3-oxo-5-beta-steroid 4-dehydrogenase OS=Rattus norvegicus GN=Akr1d1 PE=1 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 9.162e-30
Identity = 105/293 (35.84%), Postives = 143/293 (48.81%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVW---RMDESNIRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHG--HVLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNY-----DIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKF-CQKHGICVTAHTPLGGAVXNTEWFGTVS--CLDDPVLKGLPEKYXRTVAQIVLRWGIXXXXXXXXXXXXXE-TGENSRVDDFDLTKK 885
            I LN+G  +PIIGLG +   R         +  AI  GYRHID A  YRNE EVGEA+ E  + G VKRE++F   KLW++DH    V  A + +             +  P+A K    G      D +G + I    +L  TW A+E     GLV+S+G+SN+     ++ L +  L Y   KPV NQ E HPYF +  L++         + A++PL G   N  W    S   L D +L  L +KY +T AQIVLR+ I             E   EN ++ DF LTK+
Sbjct:   10 IPLNDGNSIPIIGLGTYSDPRPVPGKTFIAVKTAIDEGYRHIDGAYVYRNEHEVGEAIREKVAEGKVKREEIFYCGKLWSTDHDPEMVRPALERTLQTLKLDYIDLYIIEMPMAFK---PGEEFYPKDENGRV-IYHKSNLCATWEALEACKDAGLVKSLGVSNFNRRQLEVILNKPGLKY---KPVTNQVECHPYFTQTKLLEVSASSMTSFIVAYSPL-GTCRNPLWVNVSSPPLLKDELLTSLGKKYNKTQAQIVLRFDIQRGLVVIPKSTTPERIKENFQIFDFSLTKE 294          

BLAST of EY728655 vs. ExPASy Swiss-Prot
Match: GR_BACSU (Glyoxal reductase OS=Bacillus subtilis GN=yvgN PE=1 SV=1)

HSP 1 Score: 130.183 bits (326), Expect = 1.563e-29
Identity = 88/283 (31.10%), Postives = 139/283 (49.12%), Query Frame = 1

Query:   49 ITLNNGFKMPIIGLGVWRMDESN-IRDLIINAIKIGYRHIDCAADYRNEAEVGEALAEAFSTGLVKREDLFITTKLWNSDHGH--VLEACKDSXXXXXXXXXXXXXVHFPVATKHTGVGTTDSALDADGVLEIDTTISLETTWHAMEDLVSMGLVRSIGISNYDIFLTRDCLAYSKVKPVVNQFETHPYFQRDSLVKFCQKHGICVTAHTPLGGAVXNTEWFGTVSCLDDPVLKGLPEKYXRTVAQIVLRWGI-XXXXXXXXXXXXXETGENSRVDDFDLTKK 885
            + L+NG +MP  GLGV++++  N   + +  AIK GYR ID AA Y+NE  VG  + E+     V RE+LFIT+K+WN D G+   L A + S             +H+P   K+                        + TW A+E L   G +R+IG+SN+ +    + L  +++KP+VNQ E HP   +  L  +C+  GI + A +PL               LD+ VL  + EK+ ++VAQ++LRW +                 EN+ + DF+L+++
Sbjct:    9 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGIKESG----VAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWPGKDKY------------------------KDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQG----------QLLDNEVLTQIAEKHNKSVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQE 253