EY728543

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: MYLKF_DICDI (Probable myosin light chain kinase DDB_G0279831 OS=Dictyostelium discoideum GN=DDB_G0279831 PE=3 SV=1)

HSP 1 Score: 131.339 bits (329), Expect = 4.373e-38
Identity = 84/252 (33.33%), Postives = 122/252 (48.41%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIED--VRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVAR--------GHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFF---------------------------------RPGEQFNEIVGSPYYMAPEVLKR-NYGPEVDVWSAGVILYILLCGVPPFWAETEQGGTQAIIRSV 636
            G F   YLC +  NG+++A K I K  +       D  V  EV I+K    HP+++ + D +E +   +IV EL +GGEL  ++            +YTE  A  ++K +++ V   H   ++HRDLKPEN LF +K   S LK IDFGL+ +                                   P  +  ++ G+P + APE++KR  Y   VD+WS G+ILYILLCG PPF     QG    I+ S+
Sbjct:  575 GTFSDVYLCINKENGKQYAMKIIDKSLVTMIAQHTDMKVETEVNILKQ-SFHPHVIQIIDHFESELYYYIVTELLQGGELLYQLEKNHPSTNENVSNYTEEHARKIIKQVIQAVGFLHSNKIVHRDLKPENILFRDKSLGSILKIIDFGLASYVDHDCNCNNNNDNNNNNNNNNNNNTNGEVIQPSSPPPTKLIDVCGTPEFQAPEMVKRLGYSYPVDIWSTGIILYILLCGHPPF-----QGKNNMIVMSL 820          

HSP 2 Score: 48.521 bits (114), Expect = 4.373e-38
Identity = 19/32 (59.38%), Postives = 27/32 (84.38%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  V E+AKDL++KMLNPDP+ +LTA+++L H
Sbjct:  834 WDNVSESAKDLIRKMLNPDPEKRLTAQQVLLH 865          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: CSKP_MOUSE (Peripheral plasma membrane protein CASK OS=Mus musculus GN=Cask PE=1 SV=2)

HSP 1 Score: 143.28 bits (360), Expect = 5.697e-38
Identity = 80/206 (38.83%), Postives = 121/206 (58.74%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTA--VDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGH----YTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSV-FFRPGEQFNEIVGSPYYMAPEVLKRN-YGPEVDVWSAGVILYILLCGVPPFWAETEQ 606
            G F V   C +   G++FA K +   K  ++  +  ED++RE  I  H+ KHP+IV L +TY  D  +++V E  +G +L   IV R      Y+E  A+  M+ I+E ++ CH+  ++HRD+KP   L A+K+ S+P+K   FG+++     G      VG+P++MAPEV+KR  YG  VDVW  GVIL+ILL G  PF+   E+
Sbjct:   21 GPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASIC-HMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKER 225          

HSP 2 Score: 36.1946 bits (82), Expect = 5.697e-38
Identity = 15/32 (46.88%), Postives = 21/32 (65.62%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  + E+AKDLV++ML  DP  ++T  E L H
Sbjct:  242 WSHISESAKDLVRRMLMLDPAERITVYEALNH 273          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: CSKP_HUMAN (Peripheral plasma membrane protein CASK OS=Homo sapiens GN=CASK PE=1 SV=3)

HSP 1 Score: 143.28 bits (360), Expect = 5.697e-38
Identity = 80/206 (38.83%), Postives = 121/206 (58.74%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTA--VDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGH----YTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSV-FFRPGEQFNEIVGSPYYMAPEVLKRN-YGPEVDVWSAGVILYILLCGVPPFWAETEQ 606
            G F V   C +   G++FA K +   K  ++  +  ED++RE  I  H+ KHP+IV L +TY  D  +++V E  +G +L   IV R      Y+E  A+  M+ I+E ++ CH+  ++HRD+KP   L A+K+ S+P+K   FG+++     G      VG+P++MAPEV+KR  YG  VDVW  GVIL+ILL G  PF+   E+
Sbjct:   21 GPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASIC-HMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKER 225          

HSP 2 Score: 36.1946 bits (82), Expect = 5.697e-38
Identity = 15/32 (46.88%), Postives = 21/32 (65.62%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  + E+AKDLV++ML  DP  ++T  E L H
Sbjct:  242 WSHISESAKDLVRRMLMLDPAERITVYEALNH 273          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: CSKP_RAT (Peripheral plasma membrane protein CASK OS=Rattus norvegicus GN=Cask PE=1 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 5.698e-38
Identity = 80/206 (38.83%), Postives = 121/206 (58.74%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTA--VDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGH----YTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSV-FFRPGEQFNEIVGSPYYMAPEVLKRN-YGPEVDVWSAGVILYILLCGVPPFWAETEQ 606
            G F V   C +   G++FA K +   K  ++  +  ED++RE  I  H+ KHP+IV L +TY  D  +++V E  +G +L   IV R      Y+E  A+  M+ I+E ++ CH+  ++HRD+KP   L A+K+ S+P+K   FG+++     G      VG+P++MAPEV+KR  YG  VDVW  GVIL+ILL G  PF+   E+
Sbjct:   21 GPFSVVRRCINRETGQQFAVKIVDVAKFTSSPGLSTEDLKREASIC-HMLKHPHIVELLETYSSDGMLYMVFEFMDGADLCFEIVKRADAGFVYSEAVASHYMRQILEALRYCHDNNIIHRDVKPHCVLLASKENSAPVKLGGFGVAIQLGESGLVAGGRVGTPHFMAPEVVKREPYGKPVDVWGCGVILFILLSGCLPFYGTKER 225          

HSP 2 Score: 36.1946 bits (82), Expect = 5.698e-38
Identity = 15/32 (46.88%), Postives = 21/32 (65.62%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  + E+AKDLV++ML  DP  ++T  E L H
Sbjct:  242 WSHISESAKDLVRRMLMLDPAERITVYEALNH 273          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: PHKG2_MOUSE (Phosphorylase b kinase gamma catalytic chain, testis/liver isoform OS=Mus musculus GN=Phkg2 PE=2 SV=1)

HSP 1 Score: 142.51 bits (358), Expect = 5.753e-38
Identity = 75/205 (36.59%), Postives = 118/205 (57.56%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVD-IEDVR----REVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLK-------RNYGPEVDVWSAGVILYILLCGVPPFW 591
            G   V   C     G++FA K +     R +++ +E+VR    RE+ I++ +  HP+I++L D+YE  S + +V +L   GELFD +  +   +E+   ++M++++E V   H   ++HRDLKPEN L     ++  ++  DFG S     GE+  E+ G+P Y+APE+LK         YG EVD+W+ GVIL+ LL G PPFW
Sbjct:   33 GVSSVVRRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILL---DDNMQIRLSDFGFSCHLEAGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFW 234          

HSP 2 Score: 36.965 bits (84), Expect = 5.753e-38
Identity = 16/42 (38.10%), Postives = 26/42 (61.90%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEHLGY-KCQKAQ 781
            W       KDL+ K+L  DP+ +LTAE+ L+H  + +C+ +Q
Sbjct:  257 WDDCSNTVKDLISKLLQVDPEARLTAEQALQHPFFERCEGSQ 298          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: FHKE_DICDI (Probable serine/threonine-protein kinase fhkE OS=Dictyostelium discoideum GN=fhkE PE=3 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 7.443e-38
Identity = 78/201 (38.81%), Postives = 114/201 (56.72%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKK--LRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANK--KESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVL-----KRNYGPEVDVWSAGVILYILLCGVPPF 588
            G F    L  +   G K+A K + KKK  + ++   + +  EV I++ L  HPNI+ + + +E++  + +++EL E GEL + IV+   YTE  A  + + IV+ V   H +G+ HRDLKPEN L  +K   ++  +K  DFGLS     G     + G+P Y+APE+L        YG EVD WS G ILYI+LCG PPF
Sbjct:  154 GNFATVKLAVERTTGVKYAVKIVDKKKYFMNSSARKDSLMDEVNILRGL-SHPNIIQIIEVFENEKVLSLILELVECGELLNDIVSNLFYTEDKAKTLFRQIVDGVLYLHNKGIAHRDLKPENILLKHKNFNQNDAIKLTDFGLSRTVSDGSFMKTMCGTPQYLAPEILTSSGGHNGYGLEVDCWSMGAILYIMLCGYPPF 353          

HSP 2 Score: 35.8094 bits (81), Expect = 7.443e-38
Identity = 14/32 (43.75%), Postives = 20/32 (62.50%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  V E AKDL+K++L  DP  + T   I++H
Sbjct:  377 WSSVSEEAKDLIKRLLCVDPHKRYTCNNIIQH 408          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: DCLK3_HUMAN (Serine/threonine-protein kinase DCLK3 OS=Homo sapiens GN=DCLK3 PE=1 SV=2)

HSP 1 Score: 142.124 bits (357), Expect = 7.451e-38
Identity = 80/195 (41.03%), Postives = 119/195 (61.03%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLF-ANKKESSPLKAIDFGLSV-FFRPGEQFNEIVGSPYYMAPEVL-KRNYGPEVDVWSAGVILYILLCGVPPF 588
            G F V   C      + +A K I K +L+   D+ D   E+ I++ L  HPNIV L + YE D  +++++E  +GG+LFD I+    + E  AA ++  + + +   H++ ++HRDLKPEN L   N+ +S+ LK  DFGL+    RP      + G+P Y+APE+L ++ YG EVD+W+AGVILYILLCG PPF
Sbjct:  365 GNFAVVKECRHRETRQAYAMKIIDKSRLKGKEDMVD--SEILIIQSL-SHPNIVKLHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHRDLKPENLLVQRNEDKSTTLKLADFGLAKHVVRP---IFTVCGTPTYVAPEILSEKGYGLEVDMWAAGVILYILLCGFPPF 553          

HSP 2 Score: 36.965 bits (84), Expect = 7.451e-38
Identity = 14/32 (43.75%), Postives = 22/32 (68.75%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            W  + + AKDLV ++L  DPK + TA ++L+H
Sbjct:  579 WDNISDAAKDLVSRLLVVDPKKRYTAHQVLQH 610          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: MYLKC_DICDI (Probable myosin light chain kinase DDB_G0282429 OS=Dictyostelium discoideum GN=DDB_G0282429 PE=3 SV=1)

HSP 1 Score: 157.532 bits (397), Expect = 9.243e-38
Identity = 83/194 (42.78%), Postives = 116/194 (59.79%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLK-RNYGPEVDVWSAGVILYILLCGVPPFW 591
            G F +    T    G K A KSI+ + ++  +    + RE++IMK +  HPNI+ L + YE    +H+V+EL  GGELFD+IV RG Y+E+ A+ +++ IV  V   H  G+ HRDLKP+N L A  +E   ++  DFGLS  F  G+      GSP Y+APEVL+ + Y    D+WS GVI Y+LL G  PFW
Sbjct:   47 GAFSIVREATSRATGTKVAIKSINTRFIKNKL----LMREIEIMKKVGDHPNILKLYEVYETTKHLHLVLELVTGGELFDKIVQRGEYSEQDASKIVRQIVSAVGHLHANGIAHRDLKPQNLLCAG-EEGDDIRVADFGLSKIFGDGDYLETCCGSPEYVAPEVLECKPYDKACDLWSVGVITYVLLTGCFPFW 235          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: PHKG2_BOVIN (Phosphorylase b kinase gamma catalytic chain, testis/liver isoform OS=Bos taurus GN=PHKG2 PE=2 SV=1)

HSP 1 Score: 144.05 bits (362), Expect = 9.763e-38
Identity = 76/205 (37.07%), Postives = 117/205 (57.07%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVD-IEDVR----REVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLSVFFRPGEQFNEIVGSPYYMAPEVLK-------RNYGPEVDVWSAGVILYILLCGVPPFW 591
            G   V   C     G++FA K +     R + + +E+VR    RE  I++ +  HP+I++L D+YE  S + +V +L   GELFD +  +   +E+   ++M++++E V   H   ++HRDLKPEN L     ++  ++  DFG S    PGE+  E+ G+P Y+APE+LK         YG EVD+W+ GVIL+ LL G PPFW
Sbjct:   33 GVSSVVRRCVHRATGQEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHNNNIVHRDLKPENILL---DDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFW 234          

HSP 2 Score: 34.6538 bits (78), Expect = 9.763e-38
Identity = 15/42 (35.71%), Postives = 26/42 (61.90%), Query Frame = 2

Query:  659 WPKVPENAKDLVKKMLNPDPKPKLTAEEILEHLGY-KCQKAQ 781
            W    +  KDL+ ++L  DP  +LTAE+ L+H  + +C+ +Q
Sbjct:  257 WDDRSDTVKDLISRLLQVDPVERLTAEQALQHPFFERCEGSQ 298          

BLAST of EY728543 vs. ExPASy Swiss-Prot
Match: KS6A2_HUMAN (Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens GN=RPS6KA2 PE=1 SV=2)

HSP 1 Score: 138.272 bits (347), Expect = 1.263e-37
Identity = 77/198 (38.89%), Postives = 113/198 (57.07%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNNGEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKES-SPLKAIDFGLSVFFRPGEQFNEIVGSPYY----MAPEVLKR-NYGPEVDVWSAGVILYILLCGVPPF 588
            G + V   C       ++A K I K K        D   E++I+    +HPNI++LKD Y+D   V++VMEL  GGEL DRI+ + +++ER A+ V+ TI + +   H QGV+HRDLKP N L+ ++  S   ++  DFG +   R G   N ++ +P Y    +APEVLKR  Y    D+WS G++LY +L G  PF
Sbjct:  424 GSYSVCKRCVHKATDTEYAVKIIDKSK-------RDPSEEIEILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAG---NGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPF 611          

HSP 2 Score: 40.0466 bits (92), Expect = 1.263e-37
Identity = 17/37 (45.95%), Postives = 25/37 (67.57%), Query Frame = 2

Query:  644 LRGTPWPKVPENAKDLVKKMLNPDPKPKLTAEEILEH 754
            L G  W  + + AKD+V KML+ DP  +LTA ++L+H
Sbjct:  633 LSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKH 669          

HSP 3 Score: 85.8853 bits (211), Expect = 3.418e-16
Identity = 64/238 (26.89%), Postives = 111/238 (46.64%), Query Frame = 1

Query:   13 GEFGVTYLCTDVNN---GEKFACKSISKKKLRTAVDIEDVRREVQIMKHLPKHPNIVSLKDTYEDDSAVHIVMELCEGGELFDRIVARGHYTERAAAAVMKTIVEVVQVCHEQGVMHRDLKPENFLFANKKESSPLKAIDFGLS-VFFRPGEQFNEIVGSPYYMAPEVL-KRNYGPEVDVWSAGVILYILLCGVPPFWAETEQ------------------GGTQAIIRSVD*FKRDP 657
            G +G  +L   V     G+ +A K + K  L+    +   + E  I+  +  HP IV L   ++ +  ++++++   GG+LF R+     +TE      +  +   +   H  G+++RDLKPEN L     E   +K  DFGLS       ++     G+  YMAPEV+ +R +    D WS GV+++ +L G  PF  +  +                  G  Q+++R++  FKR+P
Sbjct:   68 GSYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRS-KMERDILAEV-NHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILL---DEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRAL--FKRNP 298